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The map label for this gene is pfbA [H]

Identifier: 52787290

GI number: 52787290

Start: 3435702

End: 3437657

Strand: Reverse

Name: pfbA [H]

Synonym: BLi03603

Alternate gene names: 52787290

Gene position: 3437657-3435702 (Counterclockwise)

Preceding gene: 52787291

Following gene: 52787289

Centisome position: 81.41

GC content: 41.92

Gene sequence:

>1956_bases
ATGCAACGGCTGATAAAAGACTATGATCAAACCCGGAATTCCCGTTATCAAGCACAACTAAGAGCAGATATGCAAAGCAT
AGAAAACAGCTTGAATGAGCAAGAAAGACAGATTCAATCGCATCAAACATCAAAAAAAGCTCATACGTCTGATCAGATTG
CTCACAGCAGCGGGCTTACAGTATCCCAAGAAATCGAAACTGCCAAAGCAAGGGCCAGAAATTTAGTGTTAAATGCCGAC
GGAACGAACATAAAGGAAGTTGTTGACGCGCGTGTTGATCGTAGGGGAACAATTTACCCGACTTTATGGGACCGTCTGGC
TGCAGATGGGCAGTATATTGAAACGAGATTTAACTTTAAAAATGCGCTTAACTATGGTGCGGACCCGACCGGAAAAAGCC
CATCTGCCTGGGCCATACAAAAGGCGCTGGATGAAATTCGTCGAGAAGGCGGCGGGCAGCTTGTGATACCAGGCGGTATT
TATTTAATCGAAAAAAGAATGATTGTGTATGAAAATACCCGTGTCACTATGGCCGCGGATTGTGTACTTCTTAGAGGATG
GGCCGGCGGATTCTTTGTCAACGGAAGGCCGGATGATAGCTTCAGCGGCTTTTCCGGAAGAAGCAACATCATTATTGAAG
GCGGTATTTTAGACGGTAACTATGCCAATATAGACAAATACCCGTCTACTGCGATGGACTCAATCATTTTAGGTCATGCA
AATAATATTTGGATTGACCGCGTAACTTTCAAAGACACGATTACCGCCCATGCCATTGATGCCAATGGGATCAACAATCT
CCAGATCACAAGGAGCAATTTTTTTGGATTCATAGACTTGAGCGGAAAACGCCCTTTCTCAGAAGCCATACAGCTTGGGG
AATTTGTTGAAATGGGCGTCAATCAATTCGGAGAGTTTGACGGCACCCCTAATCAAAACGTTTATATCGCCCATAATCAT
TTTGGTAAATCTGAGCTGTTGGGCGGCTGGGGTTCTGCGATAGGAAATCACTATGCTGTTTATGATATTTTCCAAAAAAA
CATCACAATCTTTGACAATACGATTGAGGACTGTGGTTTTGCAGGAGTAAGAACGTTTAAATGGGGCGAAGTTAAGATTT
TAAACAATCGATTTAAGCGCAATAATGAATGTATTCGAATTTCCCAAGCAGCCGGAGGAATTGAAAGTTCTAAAAATGTT
GAAGGAGTCCAAATGAATCGCCCCCAAAATGCACAAAACGTCTTGATTCAGGGAAATGATTTTTATGATTACAAGTCATA
CGGAATCTTATCGTTTGGGCAAATATATAACAACGAAGTCGCCTGGAGCGATGGCATTCGTATTTTTGGGAACTACTTTA
AATTAAAGGCAAAAGAGATTGGTGAATATGACGATGAGCAAGCCATAAAATTAGTCTTTGCAAGAAATGCTTTCATCTCT
GATAACCGGATTTTTGGGGGAAGAAGAGGGATGTGGATAGAAGGCTGTTACAACACCTTTATTGATCGAAATTATGTTTC
CTGTGTTGATACAGAAGCAATCTACGTCGAAAAAAGCAGAGACAAAACTTCTACCGTGCCGAAATCATATCACCTTTCTA
TTGATCGAAACGAAATTAACACTACTGGCCGCAACGGTATTTTCATTCAAAACTGCGATCACTTTGATGTGAGAGATAAT
AATGTGATGAATACCAATAAAGAGCAAAGCAGTACGAGAGGGCGCGGCGGCATTTATGTGGAAAACGGATACGACGGACG
AATTGAAAATAGCCGGATACGAGGCGTCGAGAAGGCGTTTGCGATTTTAGTAAAAGACGCTGCAACAGAGGTGAATGTCA
CCAACACAAAAGGGACTGGCCGCGTCATCGTTCAAGGAGATTCCAATTTTAACGGGTATTATGGGACAACAAAAGATGAC
TATATTAGAAAAATCATTACAAAAAGCAGCAGCTAA

Upstream 100 bases:

>100_bases
TCAAGCGAAAAGGCTTAGAGATCAAAAACGATATATTGACCAGCTTTTCAAAACGCTCAGGTAGGCGTTTTTTTATTTTG
CCAAAAAAGGAGTGAAAGAG

Downstream 100 bases:

>100_bases
TTGAAAGGGGAGGTGAACCAATGATTTATAAAAATACGGCTGTGCACTTTGATGTCAATGCACAAGTGAAGCGAAGTGTA
TCAGCAAATATTCAGTTCAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 651; Mature: 651

Protein sequence:

>651_residues
MQRLIKDYDQTRNSRYQAQLRADMQSIENSLNEQERQIQSHQTSKKAHTSDQIAHSSGLTVSQEIETAKARARNLVLNAD
GTNIKEVVDARVDRRGTIYPTLWDRLAADGQYIETRFNFKNALNYGADPTGKSPSAWAIQKALDEIRREGGGQLVIPGGI
YLIEKRMIVYENTRVTMAADCVLLRGWAGGFFVNGRPDDSFSGFSGRSNIIIEGGILDGNYANIDKYPSTAMDSIILGHA
NNIWIDRVTFKDTITAHAIDANGINNLQITRSNFFGFIDLSGKRPFSEAIQLGEFVEMGVNQFGEFDGTPNQNVYIAHNH
FGKSELLGGWGSAIGNHYAVYDIFQKNITIFDNTIEDCGFAGVRTFKWGEVKILNNRFKRNNECIRISQAAGGIESSKNV
EGVQMNRPQNAQNVLIQGNDFYDYKSYGILSFGQIYNNEVAWSDGIRIFGNYFKLKAKEIGEYDDEQAIKLVFARNAFIS
DNRIFGGRRGMWIEGCYNTFIDRNYVSCVDTEAIYVEKSRDKTSTVPKSYHLSIDRNEINTTGRNGIFIQNCDHFDVRDN
NVMNTNKEQSSTRGRGGIYVENGYDGRIENSRIRGVEKAFAILVKDAATEVNVTNTKGTGRVIVQGDSNFNGYYGTTKDD
YIRKIITKSSS

Sequences:

>Translated_651_residues
MQRLIKDYDQTRNSRYQAQLRADMQSIENSLNEQERQIQSHQTSKKAHTSDQIAHSSGLTVSQEIETAKARARNLVLNAD
GTNIKEVVDARVDRRGTIYPTLWDRLAADGQYIETRFNFKNALNYGADPTGKSPSAWAIQKALDEIRREGGGQLVIPGGI
YLIEKRMIVYENTRVTMAADCVLLRGWAGGFFVNGRPDDSFSGFSGRSNIIIEGGILDGNYANIDKYPSTAMDSIILGHA
NNIWIDRVTFKDTITAHAIDANGINNLQITRSNFFGFIDLSGKRPFSEAIQLGEFVEMGVNQFGEFDGTPNQNVYIAHNH
FGKSELLGGWGSAIGNHYAVYDIFQKNITIFDNTIEDCGFAGVRTFKWGEVKILNNRFKRNNECIRISQAAGGIESSKNV
EGVQMNRPQNAQNVLIQGNDFYDYKSYGILSFGQIYNNEVAWSDGIRIFGNYFKLKAKEIGEYDDEQAIKLVFARNAFIS
DNRIFGGRRGMWIEGCYNTFIDRNYVSCVDTEAIYVEKSRDKTSTVPKSYHLSIDRNEINTTGRNGIFIQNCDHFDVRDN
NVMNTNKEQSSTRGRGGIYVENGYDGRIENSRIRGVEKAFAILVKDAATEVNVTNTKGTGRVIVQGDSNFNGYYGTTKDD
YIRKIITKSSS
>Mature_651_residues
MQRLIKDYDQTRNSRYQAQLRADMQSIENSLNEQERQIQSHQTSKKAHTSDQIAHSSGLTVSQEIETAKARARNLVLNAD
GTNIKEVVDARVDRRGTIYPTLWDRLAADGQYIETRFNFKNALNYGADPTGKSPSAWAIQKALDEIRREGGGQLVIPGGI
YLIEKRMIVYENTRVTMAADCVLLRGWAGGFFVNGRPDDSFSGFSGRSNIIIEGGILDGNYANIDKYPSTAMDSIILGHA
NNIWIDRVTFKDTITAHAIDANGINNLQITRSNFFGFIDLSGKRPFSEAIQLGEFVEMGVNQFGEFDGTPNQNVYIAHNH
FGKSELLGGWGSAIGNHYAVYDIFQKNITIFDNTIEDCGFAGVRTFKWGEVKILNNRFKRNNECIRISQAAGGIESSKNV
EGVQMNRPQNAQNVLIQGNDFYDYKSYGILSFGQIYNNEVAWSDGIRIFGNYFKLKAKEIGEYDDEQAIKLVFARNAFIS
DNRIFGGRRGMWIEGCYNTFIDRNYVSCVDTEAIYVEKSRDKTSTVPKSYHLSIDRNEINTTGRNGIFIQNCDHFDVRDN
NVMNTNKEQSSTRGRGGIYVENGYDGRIENSRIRGVEKAFAILVKDAATEVNVTNTKGTGRVIVQGDSNFNGYYGTTKDD
YIRKIITKSSS

Specific function: Acts as a fibronectin-dependent adhesin and invasin. Binds host (in this case human) fibronectin, plasmin, plasminogen, and human serum albumin. Where the bacteria adhere to human cells there is major recruitment of microvilli which seem to fuse to cover

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 5 PbH1 repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005877
- InterPro:   IPR006626
- InterPro:   IPR012334
- InterPro:   IPR011050 [H]

Pfam domain/function: PF04650 YSIRK_signal [H]

EC number: NA

Molecular weight: Translated: 73126; Mature: 73126

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRLIKDYDQTRNSRYQAQLRADMQSIENSLNEQERQIQSHQTSKKAHTSDQIAHSSGLT
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCE
VSQEIETAKARARNLVLNADGTNIKEVVDARVDRRGTIYPTLWDRLAADGQYIETRFNFK
EHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHCCCCCCCHHHHHHHCCCCCEEEEEECHH
NALNYGADPTGKSPSAWAIQKALDEIRREGGGQLVIPGGIYLIEKRMIVYENTRVTMAAD
HHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCEEEEEEEEEEEECCEEEEEEE
CVLLRGWAGGFFVNGRPDDSFSGFSGRSNIIIEGGILDGNYANIDKYPSTAMDSIILGHA
EEEEEECCCCEEECCCCCCCCCCCCCCCCEEEECCEECCCCCCCCCCCCHHHHHEEEECC
NNIWIDRVTFKDTITAHAIDANGINNLQITRSNFFGFIDLSGKRPFSEAIQLGEFVEMGV
CCEEEEEEEECCCEEEEEEECCCCCCEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHH
NQFGEFDGTPNQNVYIAHNHFGKSELLGGWGSAIGNHYAVYDIFQKNITIFDNTIEDCGF
HHHCCCCCCCCCCEEEEECCCCCHHHCCCHHHHHCCCEEEEEEECCCEEEEECCHHHCCC
AGVRTFKWGEVKILNNRFKRNNECIRISQAAGGIESSKNVEGVQMNRPQNAQNVLIQGND
CCEEEEECCEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCEEECCCCCCCEEEEECCC
FYDYKSYGILSFGQIYNNEVAWSDGIRIFGNYFKLKAKEIGEYDDEQAIKLVFARNAFIS
EECCCCCCCEEEHHHHCCCEEECCCEEEEEEEEEEEEHHCCCCCCCHHEEEEEECCCEEC
DNRIFGGRRGMWIEGCYNTFIDRNYVSCVDTEAIYVEKSRDKTSTVPKSYHLSIDRNEIN
CCEEECCCCCCEEHHHHHHHHCCCCEEEECCCEEEEECCCCCCCCCCCEEEEEEECCCCC
TTGRNGIFIQNCDHFDVRDNNVMNTNKEQSSTRGRGGIYVENGYDGRIENSRIRGVEKAF
CCCCCCEEEECCCCCCCCCCCCCCCCCHHHCCCCCCCEEEECCCCCCCCCCHHHHHHHHH
AILVKDAATEVNVTNTKGTGRVIVQGDSNFNGYYGTTKDDYIRKIITKSSS
HHEEECCCCEEEEECCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MQRLIKDYDQTRNSRYQAQLRADMQSIENSLNEQERQIQSHQTSKKAHTSDQIAHSSGLT
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCE
VSQEIETAKARARNLVLNADGTNIKEVVDARVDRRGTIYPTLWDRLAADGQYIETRFNFK
EHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHCCCCCCCHHHHHHHCCCCCEEEEEECHH
NALNYGADPTGKSPSAWAIQKALDEIRREGGGQLVIPGGIYLIEKRMIVYENTRVTMAAD
HHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCEEEEEEEEEEEECCEEEEEEE
CVLLRGWAGGFFVNGRPDDSFSGFSGRSNIIIEGGILDGNYANIDKYPSTAMDSIILGHA
EEEEEECCCCEEECCCCCCCCCCCCCCCCEEEECCEECCCCCCCCCCCCHHHHHEEEECC
NNIWIDRVTFKDTITAHAIDANGINNLQITRSNFFGFIDLSGKRPFSEAIQLGEFVEMGV
CCEEEEEEEECCCEEEEEEECCCCCCEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHH
NQFGEFDGTPNQNVYIAHNHFGKSELLGGWGSAIGNHYAVYDIFQKNITIFDNTIEDCGF
HHHCCCCCCCCCCEEEEECCCCCHHHCCCHHHHHCCCEEEEEEECCCEEEEECCHHHCCC
AGVRTFKWGEVKILNNRFKRNNECIRISQAAGGIESSKNVEGVQMNRPQNAQNVLIQGND
CCEEEEECCEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCEEECCCCCCCEEEEECCC
FYDYKSYGILSFGQIYNNEVAWSDGIRIFGNYFKLKAKEIGEYDDEQAIKLVFARNAFIS
EECCCCCCCEEEHHHHCCCEEECCCEEEEEEEEEEEEHHCCCCCCCHHEEEEEECCCEEC
DNRIFGGRRGMWIEGCYNTFIDRNYVSCVDTEAIYVEKSRDKTSTVPKSYHLSIDRNEIN
CCEEECCCCCCEEHHHHHHHHCCCCEEEECCCEEEEECCCCCCCCCCCEEEEEEECCCCC
TTGRNGIFIQNCDHFDVRDNNVMNTNKEQSSTRGRGGIYVENGYDGRIENSRIRGVEKAF
CCCCCCEEEECCCCCCCCCCCCCCCCCHHHCCCCCCCEEEECCCCCCCCCCHHHHHHHHH
AILVKDAATEVNVTNTKGTGRVIVQGDSNFNGYYGTTKDDYIRKIITKSSS
HHEEECCCCEEEEECCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11544234 [H]