Click here to switch to the map view.

The map label for this gene is lexA [H]

Identifier: 52787279

GI number: 52787279

Start: 3426592

End: 3426810

Strand: Reverse

Name: lexA [H]

Synonym: BLi03592

Alternate gene names: 52787279

Gene position: 3426810-3426592 (Counterclockwise)

Preceding gene: 52787280

Following gene: 52787278

Centisome position: 81.15

GC content: 36.99

Gene sequence:

>219_bases
ATGAAAAAATCCGAACAAATATTAGAAGCCATAGACGAACTAACTAAAGAAAAAGGTTTCCCGCCATCTGTTAGGGAAAT
AGGTGAAAGGGTTGGTTTAAAATCTTCAAGTACAACAAAAGGTCATCTTGACCGGTTGCGTAAAAAGGGGCTTGTTGATT
GGGAAGAAGGTAAGCCGAGAACATTGCATATTTTGTATAAAGAAAAAGCCACCATTTAA

Upstream 100 bases:

>100_bases
TAATGCTCTGCATGCAAAAATACGTTCTCTTCCTGTAGGAAAAAGAACGAATGTTTGGTATAATTGTCATAGGTAAAACA
AACCAATGGAGGGGGATACT

Downstream 100 bases:

>100_bases
CGATTTGGAGAGACCCAAATAAATGAGACAAGGAAAAAACACCCCCTGAATCGTATTAATACAATATGATTCTTAGGAGG
GTGTTTTTCTATGGGCACAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 72; Mature: 72

Protein sequence:

>72_residues
MKKSEQILEAIDELTKEKGFPPSVREIGERVGLKSSSTTKGHLDRLRKKGLVDWEEGKPRTLHILYKEKATI

Sequences:

>Translated_72_residues
MKKSEQILEAIDELTKEKGFPPSVREIGERVGLKSSSTTKGHLDRLRKKGLVDWEEGKPRTLHILYKEKATI
>Mature_72_residues
MKKSEQILEAIDELTKEKGFPPSVREIGERVGLKSSSTTKGHLDRLRKKGLVDWEEGKPRTLHILYKEKATI

Specific function: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, recA interacts with lexA causing an autocatalytic cleavage which disrupts the DNA-binding part of lexA, lea

COG id: COG1974

COG function: function code KT; SOS-response transcriptional repressors (RecA-mediated autopeptidases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S24 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006199
- InterPro:   IPR006200
- InterPro:   IPR006197
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01726 LexA_DNA_bind; PF00717 Peptidase_S24 [H]

EC number: =3.4.21.88 [H]

Molecular weight: Translated: 8232; Mature: 8232

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKSEQILEAIDELTKEKGFPPSVREIGERVGLKSSSTTKGHLDRLRKKGLVDWEEGKPR
CCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCC
TLHILYKEKATI
EEEEEECCCCCC
>Mature Secondary Structure
MKKSEQILEAIDELTKEKGFPPSVREIGERVGLKSSSTTKGHLDRLRKKGLVDWEEGKPR
CCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCC
TLHILYKEKATI
EEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA