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The map label for this gene is yvmA [H]

Identifier: 52787254

GI number: 52787254

Start: 3410091

End: 3411317

Strand: Reverse

Name: yvmA [H]

Synonym: BLi03565

Alternate gene names: 52787254

Gene position: 3411317-3410091 (Counterclockwise)

Preceding gene: 52787257

Following gene: 52787251

Centisome position: 80.79

GC content: 47.03

Gene sequence:

>1227_bases
ATGAGACCAATGAAATCAAATGCTTCTTTCATTATGTATTTTGTGTGTATCAGCGCTTTTTTCGCATCGTTGAATCAAAA
TATTTATTCACCTATCATTCCTTTAATCAGAGACTCGTTTCACGTTTCTGTTTCGATGGTAAACCTGTCCGTCTCGCTGT
TCATCTTCATTACAGCTGCGATGCAGATCATTGTCGGCTCGATTGTTGATTTTAAAGGAGCGAGATTTGTAATGATGGCG
AGCATGATCGTAACGGTCATCGCCACAATCGGCTGCGCAGCCTCCCGGGACTTTGGCCTGTTTCTTTTTTTCAGGGTGCT
GCAGGCTTTGGGGACTGCTGCGCTTCCATTAATTGCGGCAACCACAATCGGATCTCTGTTTAAGGGAACGAAGCGGGGCA
GTGCGATGGGAACTTATCAAATGCTGCTTTCCCTTGCACCGGCAGCGGCGCCTATTCTCGGCGGTTTTATCGGGGAGCGC
TATAATTATCCGGGTATTTTTTGGTTTTTGACAGTATTGTCTGTTCTTTTGCTTTTCGGCAATTTGTTTTGCTTTCCGCG
CAGCCATTCGGAGAAAAAGACCAATCTCAGCGCGGGCAGCCTGCTGTCGCATTATAAGGACATATTCAAAAACAGGGCGG
GCAATGCCGTTTTAATATTAAGCTACCTTATTTTCTTTATTTATTTTTCAATGATCGTGTATTTGCCGATTTTGCTGACC
GATCACTATCACCTTGATCTGCAGATCGTCGGCTTGCTGTATTTGCCGATAGCGGTCAGCACGATTGCCGGCAGCGTGCT
GTTTAAGTGGATACAAAAGAGATTATCGCTCAGACGCCTGTTTTTGATCGGCAATCTGACCGCCGCAGGGAGCGTCGTCT
GTTTTGCCTTTTCCCATTTGTTTTCGCTTTTCGCCATGTCGGCGGCTCTGGTTCTTTTCGGCGTTACGATGGGGCTGATT
CCGCCGCTCTTCTCTACGATGATGGCGAATGAATTTGAGGAGAACCGCGGCAGTGCGATGGGCATGTTTAATTTTATCAG
GTATACGGGAATGGCCTGCGGTCCTGTTATATCAGGCATGTTATTGGGGATGTCATCTTCTGTTTTCGTTTTCGGCTGTT
TCGGTATCGTTTATGCCGCAGCCGCCCTTTTGATGACCGCGGTCATGCGGAAAGCAGCTCACACAAAGACGCTGCAAGAA
CCAAACAAAAAAGCTGCCAGGTCTTAA

Upstream 100 bases:

>100_bases
GACAATGATAAAGGGGTCATCTACAATTAATATTGTTAACCAGTAAACGATATTAGGTAAATTGTTAACGAATAAACAAA
AACAAGGCAGGCGGTTTGAA

Downstream 100 bases:

>100_bases
GCCGGGCAGCTTTTTGATTACAGGTCCGTTCCCCACATGTCTTCTTTCACTTGTCTTTTCTCAGACATATAGGCGAACAT
CGTAAGCGTCAGCCCGCACA

Product: YvmA

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MRPMKSNASFIMYFVCISAFFASLNQNIYSPIIPLIRDSFHVSVSMVNLSVSLFIFITAAMQIIVGSIVDFKGARFVMMA
SMIVTVIATIGCAASRDFGLFLFFRVLQALGTAALPLIAATTIGSLFKGTKRGSAMGTYQMLLSLAPAAAPILGGFIGER
YNYPGIFWFLTVLSVLLLFGNLFCFPRSHSEKKTNLSAGSLLSHYKDIFKNRAGNAVLILSYLIFFIYFSMIVYLPILLT
DHYHLDLQIVGLLYLPIAVSTIAGSVLFKWIQKRLSLRRLFLIGNLTAAGSVVCFAFSHLFSLFAMSAALVLFGVTMGLI
PPLFSTMMANEFEENRGSAMGMFNFIRYTGMACGPVISGMLLGMSSSVFVFGCFGIVYAAAALLMTAVMRKAAHTKTLQE
PNKKAARS

Sequences:

>Translated_408_residues
MRPMKSNASFIMYFVCISAFFASLNQNIYSPIIPLIRDSFHVSVSMVNLSVSLFIFITAAMQIIVGSIVDFKGARFVMMA
SMIVTVIATIGCAASRDFGLFLFFRVLQALGTAALPLIAATTIGSLFKGTKRGSAMGTYQMLLSLAPAAAPILGGFIGER
YNYPGIFWFLTVLSVLLLFGNLFCFPRSHSEKKTNLSAGSLLSHYKDIFKNRAGNAVLILSYLIFFIYFSMIVYLPILLT
DHYHLDLQIVGLLYLPIAVSTIAGSVLFKWIQKRLSLRRLFLIGNLTAAGSVVCFAFSHLFSLFAMSAALVLFGVTMGLI
PPLFSTMMANEFEENRGSAMGMFNFIRYTGMACGPVISGMLLGMSSSVFVFGCFGIVYAAAALLMTAVMRKAAHTKTLQE
PNKKAARS
>Mature_408_residues
MRPMKSNASFIMYFVCISAFFASLNQNIYSPIIPLIRDSFHVSVSMVNLSVSLFIFITAAMQIIVGSIVDFKGARFVMMA
SMIVTVIATIGCAASRDFGLFLFFRVLQALGTAALPLIAATTIGSLFKGTKRGSAMGTYQMLLSLAPAAAPILGGFIGER
YNYPGIFWFLTVLSVLLLFGNLFCFPRSHSEKKTNLSAGSLLSHYKDIFKNRAGNAVLILSYLIFFIYFSMIVYLPILLT
DHYHLDLQIVGLLYLPIAVSTIAGSVLFKWIQKRLSLRRLFLIGNLTAAGSVVCFAFSHLFSLFAMSAALVLFGVTMGLI
PPLFSTMMANEFEENRGSAMGMFNFIRYTGMACGPVISGMLLGMSSSVFVFGCFGIVYAAAALLMTAVMRKAAHTKTLQE
PNKKAARS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. TCR/tet family [H]

Homologues:

Organism=Escherichia coli, GI48994889, Length=349, Percent_Identity=21.2034383954155, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790794, Length=343, Percent_Identity=23.9067055393586, Blast_Score=65, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6324264, Length=154, Percent_Identity=27.9220779220779, Blast_Score=86, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6322071, Length=280, Percent_Identity=23.5714285714286, Blast_Score=80, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6322070, Length=302, Percent_Identity=23.1788079470199, Blast_Score=70, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6319657, Length=141, Percent_Identity=28.3687943262411, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319517, Length=164, Percent_Identity=25.609756097561, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 44589; Mature: 44589

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCC
>Mature Secondary Structure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HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]