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The map label for this gene is yvtA [H]

Identifier: 52787172

GI number: 52787172

Start: 3321875

End: 3323245

Strand: Reverse

Name: yvtA [H]

Synonym: BLi03481

Alternate gene names: 52787172

Gene position: 3323245-3321875 (Counterclockwise)

Preceding gene: 52787175

Following gene: 52787169

Centisome position: 78.7

GC content: 50.91

Gene sequence:

>1371_bases
ATGGATTTTAGACGCGATGACGAACAAAAACATGCAAATGAAGAGCAGTTTCACGAAGAAGCGCAGACGCCGCAAACGGC
AGGTTCTGAGGAGCAGCAGTCAGAACAGCCGGCAAAGGAGCCCGAGCTGATTTTAAAGAAGGATACAGACGATCAGTCAG
ATCTTACGAATAAAGAAACCGCTGCAGCCCTGGAAGATGCCAGGGAAACGAGAGCGGCAAAAGAAAAGCGGCGCAAGGCT
TCGTGGCTGAGCCCGATTTTGGGCGGGATCATCGGAGGCGGCTTGGTGCTTGGAATCTCCCCGTATCTGCCGGGCGATCA
TCCGAGCGAAACTGCCGGAACCGGACAGACAGAGCCAAAGCAGTCGCAGAATTTCACCACAAAACCTGTCACGAACGCAG
ATAACGTACCTGATATGGTGGAAGATTTGGAGCCTGCGATCGTCGGAGTTTCAAATATTCAAACGAGCTTCGGCTTCTCT
GAAGACGACGTGGAGGAGAGCGGCACGGGATCAGGCGTCATCTTTAAGAAAGACGGCGGCAAGGCCTACATTATCACAAA
CAACCATGTCGTTGAAGGCGCCTCGAAGGTGACCATCTCCTTATACAACGGAAAGACCGCGGATGCCAAGATTATCGGCA
GCGACGCTTTGACTGATCTGGCTGTTTTAGAGATCAGCAGCAAAGGCGTTGATAAGGTTGCAAGTTTCGGAGACTCCGCA
AAACTGCGCGCCGGCGAAAAAGTAATTGCGATCGGGAACCCTCTCGGCCTTCAATTTTCAAGAACGGTTACAGAAGGCAT
CATCAGCGGTGTCAACCGGACGATTGAAGTCTCAACATCTGAAGGGAATTGGGATATGAACGTCCTTCAGACAGATGCGG
CGATCAACCCTGGAAACAGCGGCGGGCCTCTGATTAACAGCAGCGGGCAGGTCATCGGCATCAACAGCCTGAAGATCAGC
CAAAGCGGTGTTGAATCGCTTGGCTTCGCGATTCCGAGCAACGATGTTCAGCCGATCGTTGACGAGCTTTTGGAAAAAGG
GAAAGTGGAACGGCCTTTCCTCGGCGTGCAAATGATCGATATGCAGCAGGTGCCTGAACAGTACCAGCAAAATACGCTCG
GCCTATTCGGAGACCAGCTTAATAAAGGCGTGTACATCGATAAAGTATCGCCGAAATCGCCTGCGGCAGACGCGGGTATG
AAAGCCGGCGACGTCATCACCAAAATGAACGGCAAAAACGTCGAAACCACCTCAGACCTCAGAAAAATTCTTTATACAGA
AGCAAAAGCAGGAGATACTGTCACATTTGAGGTGCTGAGAAACGGAAAGCAAACAACAATGAAAGCAAAACTTGCGAAAA
GCAAATCATAA

Upstream 100 bases:

>100_bases
ACAGAGTGAACGATGGCCGGGTCTCTTTTTTTGTGGATGTTAAAGCTTTAATGCCATTTGCGATAGTTGAAGACAAGAAA
AATAAAGGAAGTGTACGCTT

Downstream 100 bases:

>100_bases
ATAAAAGCCATGGCAAACGCCATGGCTTTTTCATATTACTTGTCCAAAAATGAAGAAAGCATCCAAATCTGCTTATCAAT
TTCCTCTGTCAGGGCGATAT

Product: YvtA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MDFRRDDEQKHANEEQFHEEAQTPQTAGSEEQQSEQPAKEPELILKKDTDDQSDLTNKETAAALEDARETRAAKEKRRKA
SWLSPILGGIIGGGLVLGISPYLPGDHPSETAGTGQTEPKQSQNFTTKPVTNADNVPDMVEDLEPAIVGVSNIQTSFGFS
EDDVEESGTGSGVIFKKDGGKAYIITNNHVVEGASKVTISLYNGKTADAKIIGSDALTDLAVLEISSKGVDKVASFGDSA
KLRAGEKVIAIGNPLGLQFSRTVTEGIISGVNRTIEVSTSEGNWDMNVLQTDAAINPGNSGGPLINSSGQVIGINSLKIS
QSGVESLGFAIPSNDVQPIVDELLEKGKVERPFLGVQMIDMQQVPEQYQQNTLGLFGDQLNKGVYIDKVSPKSPAADAGM
KAGDVITKMNGKNVETTSDLRKILYTEAKAGDTVTFEVLRNGKQTTMKAKLAKSKS

Sequences:

>Translated_456_residues
MDFRRDDEQKHANEEQFHEEAQTPQTAGSEEQQSEQPAKEPELILKKDTDDQSDLTNKETAAALEDARETRAAKEKRRKA
SWLSPILGGIIGGGLVLGISPYLPGDHPSETAGTGQTEPKQSQNFTTKPVTNADNVPDMVEDLEPAIVGVSNIQTSFGFS
EDDVEESGTGSGVIFKKDGGKAYIITNNHVVEGASKVTISLYNGKTADAKIIGSDALTDLAVLEISSKGVDKVASFGDSA
KLRAGEKVIAIGNPLGLQFSRTVTEGIISGVNRTIEVSTSEGNWDMNVLQTDAAINPGNSGGPLINSSGQVIGINSLKIS
QSGVESLGFAIPSNDVQPIVDELLEKGKVERPFLGVQMIDMQQVPEQYQQNTLGLFGDQLNKGVYIDKVSPKSPAADAGM
KAGDVITKMNGKNVETTSDLRKILYTEAKAGDTVTFEVLRNGKQTTMKAKLAKSKS
>Mature_456_residues
MDFRRDDEQKHANEEQFHEEAQTPQTAGSEEQQSEQPAKEPELILKKDTDDQSDLTNKETAAALEDARETRAAKEKRRKA
SWLSPILGGIIGGGLVLGISPYLPGDHPSETAGTGQTEPKQSQNFTTKPVTNADNVPDMVEDLEPAIVGVSNIQTSFGFS
EDDVEESGTGSGVIFKKDGGKAYIITNNHVVEGASKVTISLYNGKTADAKIIGSDALTDLAVLEISSKGVDKVASFGDSA
KLRAGEKVIAIGNPLGLQFSRTVTEGIISGVNRTIEVSTSEGNWDMNVLQTDAAINPGNSGGPLINSSGQVIGINSLKIS
QSGVESLGFAIPSNDVQPIVDELLEKGKVERPFLGVQMIDMQQVPEQYQQNTLGLFGDQLNKGVYIDKVSPKSPAADAGM
KAGDVITKMNGKNVETTSDLRKILYTEAKAGDTVTFEVLRNGKQTTMKAKLAKSKS

Specific function: May be involved in processing, maturation, or secretion of extracellular enzymes [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=344, Percent_Identity=35.1744186046512, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI22129776, Length=313, Percent_Identity=35.1437699680511, Blast_Score=149, Evalue=7e-36,
Organism=Homo sapiens, GI24308541, Length=315, Percent_Identity=35.8730158730159, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI7019477, Length=321, Percent_Identity=33.0218068535826, Blast_Score=132, Evalue=6e-31,
Organism=Escherichia coli, GI1789629, Length=361, Percent_Identity=35.1800554016621, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI1786356, Length=298, Percent_Identity=37.9194630872483, Blast_Score=178, Evalue=5e-46,
Organism=Escherichia coli, GI1789630, Length=322, Percent_Identity=35.7142857142857, Blast_Score=159, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24646839, Length=291, Percent_Identity=36.7697594501718, Blast_Score=140, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 48667; Mature: 48667

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFRRDDEQKHANEEQFHEEAQTPQTAGSEEQQSEQPAKEPELILKKDTDDQSDLTNKET
CCCCCCCHHHHCCHHHHHHHHCCCCCCCCCHHHHCCCCCCCCEEEECCCCCHHHCCCHHH
AAALEDARETRAAKEKRRKASWLSPILGGIIGGGLVLGISPYLPGDHPSETAGTGQTEPK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCC
QSQNFTTKPVTNADNVPDMVEDLEPAIVGVSNIQTSFGFSEDDVEESGTGSGVIFKKDGG
CCCCCCCCCCCCCCCCHHHHHHCCHHHEEHHHHHHHCCCCHHHHHHCCCCCEEEEEECCC
KAYIITNNHVVEGASKVTISLYNGKTADAKIIGSDALTDLAVLEISSKGVDKVASFGDSA
EEEEEECCEEECCCCEEEEEEECCCCCCEEEECCHHHHHEEEEEECCCCHHHHHHCCCCC
KLRAGEKVIAIGNPLGLQFSRTVTEGIISGVNRTIEVSTSEGNWDMNVLQTDAAINPGNS
EECCCCEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCCCCCCCC
GGPLINSSGQVIGINSLKISQSGVESLGFAIPSNDVQPIVDELLEKGKVERPFLGVQMID
CCCEECCCCCEEEEEEEEECHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEHH
MQQVPEQYQQNTLGLFGDQLNKGVYIDKVSPKSPAADAGMKAGDVITKMNGKNVETTSDL
HHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHH
RKILYTEAKAGDTVTFEVLRNGKQTTMKAKLAKSKS
HHHHHHHCCCCCEEEHHHHHCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MDFRRDDEQKHANEEQFHEEAQTPQTAGSEEQQSEQPAKEPELILKKDTDDQSDLTNKET
CCCCCCCHHHHCCHHHHHHHHCCCCCCCCCHHHHCCCCCCCCEEEECCCCCHHHCCCHHH
AAALEDARETRAAKEKRRKASWLSPILGGIIGGGLVLGISPYLPGDHPSETAGTGQTEPK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCC
QSQNFTTKPVTNADNVPDMVEDLEPAIVGVSNIQTSFGFSEDDVEESGTGSGVIFKKDGG
CCCCCCCCCCCCCCCCHHHHHHCCHHHEEHHHHHHHCCCCHHHHHHCCCCCEEEEEECCC
KAYIITNNHVVEGASKVTISLYNGKTADAKIIGSDALTDLAVLEISSKGVDKVASFGDSA
EEEEEECCEEECCCCEEEEEEECCCCCCEEEECCHHHHHEEEEEECCCCHHHHHHCCCCC
KLRAGEKVIAIGNPLGLQFSRTVTEGIISGVNRTIEVSTSEGNWDMNVLQTDAAINPGNS
EECCCCEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCCCCCCCC
GGPLINSSGQVIGINSLKISQSGVESLGFAIPSNDVQPIVDELLEKGKVERPFLGVQMID
CCCEECCCCCEEEEEEEEECHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEHH
MQQVPEQYQQNTLGLFGDQLNKGVYIDKVSPKSPAADAGMKAGDVITKMNGKNVETTSDL
HHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHH
RKILYTEAKAGDTVTFEVLRNGKQTTMKAKLAKSKS
HHHHHHHCCCCCEEEHHHHHCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10692364; 9353931; 9384377; 10568751; 11133960 [H]