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The map label for this gene is comP [H]

Identifier: 52787052

GI number: 52787052

Start: 3208224

End: 3209375

Strand: Reverse

Name: comP [H]

Synonym: BLi03357

Alternate gene names: 52787052

Gene position: 3209375-3208224 (Counterclockwise)

Preceding gene: 52787053

Following gene: 52787051

Centisome position: 76.0

GC content: 29.86

Gene sequence:

>1152_bases
ATGCGTGTTAATTATAATAAACTATCTTTAATTATTATTTTGCTAAGCCTCTCCTTGGTTCCTTATATTATCTATGTAAA
TCTGCATTCTAGTTACCTTGGAATGACAATGCAATTTAATGAAAAAAACGAATACCAAGTATTCGAGATTGAAAAAGGGT
CACTGGCTCAATCCCTAGGATTTAAAAAAGGGGATGTTATTCTAGAGATAAATGGTAAAAGTGTAGAAAAATTAAGGGCT
GATGATGGGAAATTAGCTGATGAATTAAGTGATGTTAAATCGATGATCGTTGAAAGAGATGGAGAGATAGGGTTTGTAGA
GACCGGATATGAATTGGTGAGTTATGAAAGTCTATTTCTATTTATTATTCCAATGATGTTTTATCTCCTTTCTCTTTTTT
GTGTTTATTTCATAATAAAATCAAACAAAAGATTAAATTCGGCTTCAGCTTTTATTTTAATTGTTTTTCTGCTTGTTACA
TCAACAGCTTATTCTTGTTCTGTGGGATCTGCAAAGGGAGATAGTTTAAGTATCTATATAACAATGATAACTTTTCAATT
CGTTCCTGTTTTGTATCTCCACTATATTTATCAATATTTCAAGGAAAAAGGAAAAGAGTTTTTCAATAATAAAATATTTC
TTTTCCTATACCCTGTGGGTTTATTGAATTTGCTATTGGAAATTTCCAGTGATAATTTGCAGATTTCTTATAGTTCCATT
AAGCTCTTTAACCTGGTATCTTTCTTGGTTGTTACCATTATAGCCTTTGCTCTTATCATTTATGGTGTAATAAAAAATAA
AGCTTCTGAGCAAGCCTATTTTTTAAGGATACTTGTTATCACAAATTTTGTTGCGTTTATTCCGTTCTTAATTTTCTATG
TCATTCCATATGTATTTATCGGTGATTATATATTCCCGGCAATGTTTGTTGTACCCTTTTTGTTGATTATTCCTTTCTCA
TTAGTGTATCAATTTATTGCTACCAAAATATATGACATTGAATTCTTATTGGGACGTTTTAAATACTATGGATTGTTAGC
CATTTTACCAAGCTTGACAGCTGTAGGTGTATTTACTTTAACACAAGAATTAAGTAATAGTCTAAATACAGTTAAAAACA
CTATATTTATCTATTTGGAGAGACCCAAATAA

Upstream 100 bases:

>100_bases
AGTGGTTGACAGTATTAGATTATTAGGTAAGAGTTGGGGTGGAGGAGGATTTTGGATTTAAAATTCTTCCTTAACTATCT
ATTATAAGGATGTAAAATTA

Downstream 100 bases:

>100_bases
ATGAGACAAGGAAAAAACACCCCCTGAATCGTATTAATACAATATGATTCTTAGGAGGGTGTTTTTCTATGGGCACAAGA
GTACATTACGCAGAAGAAGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MRVNYNKLSLIIILLSLSLVPYIIYVNLHSSYLGMTMQFNEKNEYQVFEIEKGSLAQSLGFKKGDVILEINGKSVEKLRA
DDGKLADELSDVKSMIVERDGEIGFVETGYELVSYESLFLFIIPMMFYLLSLFCVYFIIKSNKRLNSASAFILIVFLLVT
STAYSCSVGSAKGDSLSIYITMITFQFVPVLYLHYIYQYFKEKGKEFFNNKIFLFLYPVGLLNLLLEISSDNLQISYSSI
KLFNLVSFLVVTIIAFALIIYGVIKNKASEQAYFLRILVITNFVAFIPFLIFYVIPYVFIGDYIFPAMFVVPFLLIIPFS
LVYQFIATKIYDIEFLLGRFKYYGLLAILPSLTAVGVFTLTQELSNSLNTVKNTIFIYLERPK

Sequences:

>Translated_383_residues
MRVNYNKLSLIIILLSLSLVPYIIYVNLHSSYLGMTMQFNEKNEYQVFEIEKGSLAQSLGFKKGDVILEINGKSVEKLRA
DDGKLADELSDVKSMIVERDGEIGFVETGYELVSYESLFLFIIPMMFYLLSLFCVYFIIKSNKRLNSASAFILIVFLLVT
STAYSCSVGSAKGDSLSIYITMITFQFVPVLYLHYIYQYFKEKGKEFFNNKIFLFLYPVGLLNLLLEISSDNLQISYSSI
KLFNLVSFLVVTIIAFALIIYGVIKNKASEQAYFLRILVITNFVAFIPFLIFYVIPYVFIGDYIFPAMFVVPFLLIIPFS
LVYQFIATKIYDIEFLLGRFKYYGLLAILPSLTAVGVFTLTQELSNSLNTVKNTIFIYLERPK
>Mature_383_residues
MRVNYNKLSLIIILLSLSLVPYIIYVNLHSSYLGMTMQFNEKNEYQVFEIEKGSLAQSLGFKKGDVILEINGKSVEKLRA
DDGKLADELSDVKSMIVERDGEIGFVETGYELVSYESLFLFIIPMMFYLLSLFCVYFIIKSNKRLNSASAFILIVFLLVT
STAYSCSVGSAKGDSLSIYITMITFQFVPVLYLHYIYQYFKEKGKEFFNNKIFLFLYPVGLLNLLLEISSDNLQISYSSI
KLFNLVSFLVVTIIAFALIIYGVIKNKASEQAYFLRILVITNFVAFIPFLIFYVIPYVFIGDYIFPAMFVVPFLLIIPFS
LVYQFIATKIYDIEFLLGRFKYYGLLAILPSLTAVGVFTLTQELSNSLNTVKNTIFIYLERPK

Specific function: Sensor in the two-component regulatory system ComP/ComA involved in a major quorum response pathway that regulates the development of genetic competence. Plays a role in sporulation, at least partly interchangeable with that of SpoIIJ. Probably activates

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011712
- InterPro:   IPR005467 [H]

Pfam domain/function: PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 43903; Mature: 43903

Theoretical pI: Translated: 8.07; Mature: 8.07

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVNYNKLSLIIILLSLSLVPYIIYVNLHSSYLGMTMQFNEKNEYQVFEIEKGSLAQSLG
CCCCHHHHHHHHHHHHHHHHHEEEEEEECCHHHCEEEEECCCCCEEEEEECCCCHHHHCC
FKKGDVILEINGKSVEKLRADDGKLADELSDVKSMIVERDGEIGFVETGYELVSYESLFL
CCCCCEEEEECCCHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHH
FIIPMMFYLLSLFCVYFIIKSNKRLNSASAFILIVFLLVTSTAYSCSVGSAKGDSLSIYI
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEE
TMITFQFVPVLYLHYIYQYFKEKGKEFFNNKIFLFLYPVGLLNLLLEISSDNLQISYSSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHCCCCCEEEEEHHH
KLFNLVSFLVVTIIAFALIIYGVIKNKASEQAYFLRILVITNFVAFIPFLIFYVIPYVFI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GDYIFPAMFVVPFLLIIPFSLVYQFIATKIYDIEFLLGRFKYYGLLAILPSLTAVGVFTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQELSNSLNTVKNTIFIYLERPK
HHHHHHHHHHHHCEEEEEEECCC
>Mature Secondary Structure
MRVNYNKLSLIIILLSLSLVPYIIYVNLHSSYLGMTMQFNEKNEYQVFEIEKGSLAQSLG
CCCCHHHHHHHHHHHHHHHHHEEEEEEECCHHHCEEEEECCCCCEEEEEECCCCHHHHCC
FKKGDVILEINGKSVEKLRADDGKLADELSDVKSMIVERDGEIGFVETGYELVSYESLFL
CCCCCEEEEECCCHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHH
FIIPMMFYLLSLFCVYFIIKSNKRLNSASAFILIVFLLVTSTAYSCSVGSAKGDSLSIYI
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEE
TMITFQFVPVLYLHYIYQYFKEKGKEFFNNKIFLFLYPVGLLNLLLEISSDNLQISYSSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHCCCCCEEEEEHHH
KLFNLVSFLVVTIIAFALIIYGVIKNKASEQAYFLRILVITNFVAFIPFLIFYVIPYVFI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GDYIFPAMFVVPFLLIIPFSLVYQFIATKIYDIEFLLGRFKYYGLLAILPSLTAVGVFTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQELSNSLNTVKNTIFIYLERPK
HHHHHHHHHHHHCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2116363; 9274030; 9384377; 1715859 [H]