Click here to switch to the map view.

The map label for this gene is sglT [H]

Identifier: 52786972

GI number: 52786972

Start: 3138072

End: 3139700

Strand: Direct

Name: sglT [H]

Synonym: BLi03272

Alternate gene names: 52786972

Gene position: 3138072-3139700 (Clockwise)

Preceding gene: 52786971

Following gene: 52786975

Centisome position: 74.32

GC content: 49.91

Gene sequence:

>1629_bases
ATGAATTATGCTGAGAAGAAAAAAAACTGGATCAAATTAGGTATTTTTGCGCTGTTTGCGGGAGGCATACTCGCGTATAT
CGGCATTTCGAATGCGGACATTCATTGGGGCGGCTTTATCTCCATGATGATATTCTTTGCTTTCACCTATTATTTAGGCG
CTTTTTACGCAGCAAAGAAATCAAATTCTTTTTCCGATATGATCGTGGCAAAAAGGAGCATGCCGTTTTTCGTCGGAATG
GTGACGATGGCCGCAACATGGGTCGGCGGCGGATATATTAACGGAACGGCCGAATCGACTTACAGCGACGGCCTCATCTG
GGCCCAAGCGCCTTGGGGCTACGCATTGAGCCTGATTATCGGCGGTATTTTCTTCGCCAGAAAAATGCGCCGTCATCAAT
TTATGACCATTATCGATCCTCTCGAACAGCGCTTCGGTAAGCGGATGGCCGGCGTTTTATATATACCGGCGCTGTTAGGA
GAATTGTTTTGGAGCGCCGCGATCTTAACGGCATTGGGCACGACTTTCGGAATGATTCTGAATATCGATTTCCAAACGTC
GATTATTCTTTCGGCGATGATCGCCATCGCTTATACGGTGGCCGGAGGCATGTGGGCAGTTGCTTTCACAGATGTCTTTC
AAATGATTGTCATTTTGCTCGGGCTGTTTTTAGTCGTCCCATTTGTATTGTCGAATGTCGGTGCTCTCGATAGCGTATGG
GCAAATTACAGGCACGATTTCGGCAGCAGCGCCAATCTGCTTCCGCCGTTGGACGGCTGGAAAAACCCGGATTGGGGAAA
CCTGTTTTGGAACTGGTGGGATAATGCGCTCCTCTTAATTTTCGGAGGTATCGCATGGCAGGTGTACTTTCAGCGCGTTC
TTTCGGCAAAATCGGAAAGCGCCGCCATGTGGCAGTCGATAATTGCCGGAGTGATCTGCATCATTGCCGCCATTCCGTGC
GTAATCATCGGAGCTGCCGGAAACAGTACCGATTGGAGCCTGTTCGGAGCGAGCGCTCCGGATAACCCGGCGATGATTTT
GCCGCAAACGCTTGCGTATTTGACGCCAGGAATCATCGCAGGCCTCGGCTTGGGTGCAATCGCAGCAGCCGTCATGTCAA
GCATGGACTCATCGATTCTATCGGCATCATCAATGGCCGCATGGAATATTTACCGTCCGCTCATCAAGCCGAAGGCCACC
CAAAAACAGCTGCAAAAAGTCGTCAAACGCTCAATCATTTTGTTCGGCGCGGGAGCAGCGGTCATCGCGCTGAATGTCAA
AAGCGTTTATACTTTATGGTATTTGGCTTCGGATTTAGTTTATTGCATTCTTTTTCCCCAGTTAACAATGGCCCTCTTTT
ATAAAAGAGCAAATCTTTACGGGTCGATTGCTGGATTTGCAGTTGCAGTCATTCTGAGGCTCGGCGGTGGTGAACCCGCA
TTCGGCATTCCGCCGCTTCTGCCGTATCCGATGATTGAAGACGGCACGGTCCTCTTTCCTTTCCGGACGCTGGCTGCAGT
CACAGCATTTATGACGATCTTCGCTGTGTCCGAATTGACGCAGCGCAAATGCCCTCCTAAACAGCTTGTACTCCCCCAAG
AAAAACAGAAAGACGACCGCGCGGCTTAA

Upstream 100 bases:

>100_bases
AAGTCAGCAATTTGCATACTTCCCAGAGTGGGGCAAAACCTTTTTTCATATTTTAATTTCAAGAAAATTCAAAAAATATT
TTCGGAGGCGATGTGCATAC

Downstream 100 bases:

>100_bases
ATAGGAAAAACGCCCGGCCCCGGGCGTTTTTCTAGATTTATGTTTATTTTTTTACGGCAAGAATGTAATGAATCGTTTCA
AAGGCTGACAGATCATCTTT

Product: hypothetical protein

Products: Na (I) [Cytoplasm]; pantothenate [Cytoplasm] [C]

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 542; Mature: 542

Protein sequence:

>542_residues
MNYAEKKKNWIKLGIFALFAGGILAYIGISNADIHWGGFISMMIFFAFTYYLGAFYAAKKSNSFSDMIVAKRSMPFFVGM
VTMAATWVGGGYINGTAESTYSDGLIWAQAPWGYALSLIIGGIFFARKMRRHQFMTIIDPLEQRFGKRMAGVLYIPALLG
ELFWSAAILTALGTTFGMILNIDFQTSIILSAMIAIAYTVAGGMWAVAFTDVFQMIVILLGLFLVVPFVLSNVGALDSVW
ANYRHDFGSSANLLPPLDGWKNPDWGNLFWNWWDNALLLIFGGIAWQVYFQRVLSAKSESAAMWQSIIAGVICIIAAIPC
VIIGAAGNSTDWSLFGASAPDNPAMILPQTLAYLTPGIIAGLGLGAIAAAVMSSMDSSILSASSMAAWNIYRPLIKPKAT
QKQLQKVVKRSIILFGAGAAVIALNVKSVYTLWYLASDLVYCILFPQLTMALFYKRANLYGSIAGFAVAVILRLGGGEPA
FGIPPLLPYPMIEDGTVLFPFRTLAAVTAFMTIFAVSELTQRKCPPKQLVLPQEKQKDDRAA

Sequences:

>Translated_542_residues
MNYAEKKKNWIKLGIFALFAGGILAYIGISNADIHWGGFISMMIFFAFTYYLGAFYAAKKSNSFSDMIVAKRSMPFFVGM
VTMAATWVGGGYINGTAESTYSDGLIWAQAPWGYALSLIIGGIFFARKMRRHQFMTIIDPLEQRFGKRMAGVLYIPALLG
ELFWSAAILTALGTTFGMILNIDFQTSIILSAMIAIAYTVAGGMWAVAFTDVFQMIVILLGLFLVVPFVLSNVGALDSVW
ANYRHDFGSSANLLPPLDGWKNPDWGNLFWNWWDNALLLIFGGIAWQVYFQRVLSAKSESAAMWQSIIAGVICIIAAIPC
VIIGAAGNSTDWSLFGASAPDNPAMILPQTLAYLTPGIIAGLGLGAIAAAVMSSMDSSILSASSMAAWNIYRPLIKPKAT
QKQLQKVVKRSIILFGAGAAVIALNVKSVYTLWYLASDLVYCILFPQLTMALFYKRANLYGSIAGFAVAVILRLGGGEPA
FGIPPLLPYPMIEDGTVLFPFRTLAAVTAFMTIFAVSELTQRKCPPKQLVLPQEKQKDDRAA
>Mature_542_residues
MNYAEKKKNWIKLGIFALFAGGILAYIGISNADIHWGGFISMMIFFAFTYYLGAFYAAKKSNSFSDMIVAKRSMPFFVGM
VTMAATWVGGGYINGTAESTYSDGLIWAQAPWGYALSLIIGGIFFARKMRRHQFMTIIDPLEQRFGKRMAGVLYIPALLG
ELFWSAAILTALGTTFGMILNIDFQTSIILSAMIAIAYTVAGGMWAVAFTDVFQMIVILLGLFLVVPFVLSNVGALDSVW
ANYRHDFGSSANLLPPLDGWKNPDWGNLFWNWWDNALLLIFGGIAWQVYFQRVLSAKSESAAMWQSIIAGVICIIAAIPC
VIIGAAGNSTDWSLFGASAPDNPAMILPQTLAYLTPGIIAGLGLGAIAAAVMSSMDSSILSASSMAAWNIYRPLIKPKAT
QKQLQKVVKRSIILFGAGAAVIALNVKSVYTLWYLASDLVYCILFPQLTMALFYKRANLYGSIAGFAVAVILRLGGGEPA
FGIPPLLPYPMIEDGTVLFPFRTLAAVTAFMTIFAVSELTQRKCPPKQLVLPQEKQKDDRAA

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI11141885, Length=520, Percent_Identity=45, Blast_Score=409, Evalue=1e-114,
Organism=Homo sapiens, GI4507035, Length=400, Percent_Identity=23.5, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI4507031, Length=436, Percent_Identity=24.0825688073394, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI110835708, Length=544, Percent_Identity=24.6323529411765, Blast_Score=70, Evalue=7e-12,
Organism=Homo sapiens, GI109659836, Length=505, Percent_Identity=24.1584158415842, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI109659839, Length=521, Percent_Identity=24.3761996161228, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI256985183, Length=362, Percent_Identity=23.7569060773481, Blast_Score=68, Evalue=3e-11,
Organism=Homo sapiens, GI17941285, Length=400, Percent_Identity=23.5, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI87082237, Length=376, Percent_Identity=25.7978723404255, Blast_Score=66, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17539284, Length=507, Percent_Identity=44.1814595660749, Blast_Score=417, Evalue=1e-117,
Organism=Drosophila melanogaster, GI24648033, Length=526, Percent_Identity=44.106463878327, Blast_Score=409, Evalue=1e-114,
Organism=Drosophila melanogaster, GI21356865, Length=526, Percent_Identity=44.106463878327, Blast_Score=409, Evalue=1e-114,
Organism=Drosophila melanogaster, GI24650192, Length=354, Percent_Identity=24.0112994350282, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI28573698, Length=453, Percent_Identity=22.5165562913907, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 59060; Mature: 59060

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYAEKKKNWIKLGIFALFAGGILAYIGISNADIHWGGFISMMIFFAFTYYLGAFYAAKK
CCCHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
SNSFSDMIVAKRSMPFFVGMVTMAATWVGGGYINGTAESTYSDGLIWAQAPWGYALSLII
CCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCEECCCCCCCCCCCEEEEECCHHHHHHHHH
GGIFFARKMRRHQFMTIIDPLEQRFGKRMAGVLYIPALLGELFWSAAILTALGTTFGMIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
NIDFQTSIILSAMIAIAYTVAGGMWAVAFTDVFQMIVILLGLFLVVPFVLSNVGALDSVW
EECHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
ANYRHDFGSSANLLPPLDGWKNPDWGNLFWNWWDNALLLIFGGIAWQVYFQRVLSAKSES
HHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHH
AAMWQSIIAGVICIIAAIPCVIIGAAGNSTDWSLFGASAPDNPAMILPQTLAYLTPGIIA
HHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCEEEECCCCCCCCEEHHHHHHHHCHHHHH
GLGLGAIAAAVMSSMDSSILSASSMAAWNIYRPLIKPKATQKQLQKVVKRSIILFGAGAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEEEECCCE
VIALNVKSVYTLWYLASDLVYCILFPQLTMALFYKRANLYGSIAGFAVAVILRLGGGEPA
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
FGIPPLLPYPMIEDGTVLFPFRTLAAVTAFMTIFAVSELTQRKCPPKQLVLPQEKQKDDR
CCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCHHCCCCC
AA
CC
>Mature Secondary Structure
MNYAEKKKNWIKLGIFALFAGGILAYIGISNADIHWGGFISMMIFFAFTYYLGAFYAAKK
CCCHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
SNSFSDMIVAKRSMPFFVGMVTMAATWVGGGYINGTAESTYSDGLIWAQAPWGYALSLII
CCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCEECCCCCCCCCCCEEEEECCHHHHHHHHH
GGIFFARKMRRHQFMTIIDPLEQRFGKRMAGVLYIPALLGELFWSAAILTALGTTFGMIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
NIDFQTSIILSAMIAIAYTVAGGMWAVAFTDVFQMIVILLGLFLVVPFVLSNVGALDSVW
EECHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
ANYRHDFGSSANLLPPLDGWKNPDWGNLFWNWWDNALLLIFGGIAWQVYFQRVLSAKSES
HHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHH
AAMWQSIIAGVICIIAAIPCVIIGAAGNSTDWSLFGASAPDNPAMILPQTLAYLTPGIIA
HHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCEEEECCCCCCCCEEHHHHHHHHCHHHHH
GLGLGAIAAAVMSSMDSSILSASSMAAWNIYRPLIKPKATQKQLQKVVKRSIILFGAGAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEEEECCCE
VIALNVKSVYTLWYLASDLVYCILFPQLTMALFYKRANLYGSIAGFAVAVILRLGGGEPA
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
FGIPPLLPYPMIEDGTVLFPFRTLAAVTAFMTIFAVSELTQRKCPPKQLVLPQEKQKDDR
CCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCHHCCCCC
AA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; pantothenate [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + pantothenate [Periplasm] = Na (I) [Cytoplasm] + pantothenate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]