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The map label for this gene is acuC [H]

Identifier: 52786847

GI number: 52786847

Start: 3004453

End: 3005613

Strand: Direct

Name: acuC [H]

Synonym: BLi03122

Alternate gene names: 52786847

Gene position: 3004453-3005613 (Clockwise)

Preceding gene: 52786846

Following gene: 52786861

Centisome position: 71.15

GC content: 50.65

Gene sequence:

>1161_bases
ATGAAGGACAGCGTATTTATTTTTTCTCCCTCATATCAAACCTATCAATTTCATCAAGACCACCCGTTTAATCAGCTGCG
AGTCTATGTAACATACGATCTTTTGAACACGGTCGGCGCATTTGAACCGGGAGAAACGATTGCCCCGCGCGCAGCGACAG
AAACCGAGCTCGAGCTTGTTCACACGGGCGATTATATCAGGGCCGTCCAGCTTGCAGGGGCGGGAAAGCTCCCGGCAGCC
GAAAGCGAAAACTACGGGCTTGGAACGGAGGATACCCCTGTTTTTGCCGGGATGCATGAAGCCGCCTCCCTTTTGGTAGG
CGGAACGCTGACGGCTGCAGACTATGTCATGACGGGCAAAGCTAGACACGCCCTCAATCTTGGAGGCGGGCTTCACCACG
GGTTCAGAGGAAGGGCTTCAGGCTTTTGCGTCTATAATGACAGTTCAGTTGTGATACGTTACTTGCAGAAAAAATATCAT
GCGAAAGTTTTATATATTGATACAGACGCCCATCACGGCGACGGGGTGCAGTTTACGTTCTATGATGATCCTTCCGTCTG
CACCGTCTCGATACATGAAACAGGCCGCTACCTATTCCCGGGAACGGGGCAGGTTCAGGAAAGAGGTCATGGCGAAGGCT
ACGGCTATGCTTTTAATATCCCGCTCGATGCCTTCACAGAAGATGAGTCTTTTCTTGATTCCTACCGGACGGCTGTTTCT
GAAATAGCCGAGTTTTTCAAACCGGATGTCATTTTGTCGCAAAACGGAGCTGACGCACATTACTACGATCCGCTGACACA
CTTGTGCACGACGATGAAGATTTACGAAGAGATTCCAAAGCTCGCTCACGAACTTGCACACACCTATTGCAGCGGAAGAT
GGATCGCTGTCGGCGGAGGCGGCTACGACATTTGGCGCGTCGTACCGAGGGCATGGGCAAGAATCTGGCTTGAAATGAAA
GGGATGGAACCAGAGGAGAAAATGCCTGAAAAATGGCTGAAAAAATGGGGGAAACAGGCATCTGTCCGGCTTCCTGCCAA
CTGGTCCGACCCGGAAGATTTGTATCCTCCAATTCCAAGAAAAACCGAAATAACGGAAAAAAACGCACAAACCGTTGCCA
AAGCCCTTTATCCGATTCGCTCTGCCCAGCGTACCACTTAA

Upstream 100 bases:

>100_bases
TCGTGTTTCGCGTTCAAACGATGAATCCCGCCTCTATCATCAAAGACGTAAAATCCAAAGGGTATCAGGTTCTTTGGCCG
GCTGTTCAAAGGGATTTGCC

Downstream 100 bases:

>100_bases
TATGAAAATTGCGGCACACAGAAAAGGCCTTGCTTTTGTGCAAGACCTTGCTTTCTTCTCATTATTGTTTTGCGATGACA
ATCTCGACGCGCCTGTTTTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MKDSVFIFSPSYQTYQFHQDHPFNQLRVYVTYDLLNTVGAFEPGETIAPRAATETELELVHTGDYIRAVQLAGAGKLPAA
ESENYGLGTEDTPVFAGMHEAASLLVGGTLTAADYVMTGKARHALNLGGGLHHGFRGRASGFCVYNDSSVVIRYLQKKYH
AKVLYIDTDAHHGDGVQFTFYDDPSVCTVSIHETGRYLFPGTGQVQERGHGEGYGYAFNIPLDAFTEDESFLDSYRTAVS
EIAEFFKPDVILSQNGADAHYYDPLTHLCTTMKIYEEIPKLAHELAHTYCSGRWIAVGGGGYDIWRVVPRAWARIWLEMK
GMEPEEKMPEKWLKKWGKQASVRLPANWSDPEDLYPPIPRKTEITEKNAQTVAKALYPIRSAQRTT

Sequences:

>Translated_386_residues
MKDSVFIFSPSYQTYQFHQDHPFNQLRVYVTYDLLNTVGAFEPGETIAPRAATETELELVHTGDYIRAVQLAGAGKLPAA
ESENYGLGTEDTPVFAGMHEAASLLVGGTLTAADYVMTGKARHALNLGGGLHHGFRGRASGFCVYNDSSVVIRYLQKKYH
AKVLYIDTDAHHGDGVQFTFYDDPSVCTVSIHETGRYLFPGTGQVQERGHGEGYGYAFNIPLDAFTEDESFLDSYRTAVS
EIAEFFKPDVILSQNGADAHYYDPLTHLCTTMKIYEEIPKLAHELAHTYCSGRWIAVGGGGYDIWRVVPRAWARIWLEMK
GMEPEEKMPEKWLKKWGKQASVRLPANWSDPEDLYPPIPRKTEITEKNAQTVAKALYPIRSAQRTT
>Mature_386_residues
MKDSVFIFSPSYQTYQFHQDHPFNQLRVYVTYDLLNTVGAFEPGETIAPRAATETELELVHTGDYIRAVQLAGAGKLPAA
ESENYGLGTEDTPVFAGMHEAASLLVGGTLTAADYVMTGKARHALNLGGGLHHGFRGRASGFCVYNDSSVVIRYLQKKYH
AKVLYIDTDAHHGDGVQFTFYDDPSVCTVSIHETGRYLFPGTGQVQERGHGEGYGYAFNIPLDAFTEDESFLDSYRTAVS
EIAEFFKPDVILSQNGADAHYYDPLTHLCTTMKIYEEIPKLAHELAHTYCSGRWIAVGGGGYDIWRVVPRAWARIWLEMK
GMEPEEKMPEKWLKKWGKQASVRLPANWSDPEDLYPPIPRKTEITEKNAQTVAKALYPIRSAQRTT

Specific function: Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI13128860, Length=301, Percent_Identity=35.2159468438538, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI293336691, Length=274, Percent_Identity=35.036496350365, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI13128862, Length=332, Percent_Identity=31.6265060240964, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI8923769, Length=321, Percent_Identity=30.8411214953271, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI262073092, Length=228, Percent_Identity=33.3333333333333, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI30795204, Length=315, Percent_Identity=30.1587301587302, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI30795202, Length=315, Percent_Identity=30.1587301587302, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI17158039, Length=315, Percent_Identity=30.1587301587302, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI20070354, Length=297, Percent_Identity=29.2929292929293, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI153085395, Length=351, Percent_Identity=29.6296296296296, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI262073088, Length=202, Percent_Identity=33.6633663366337, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI62750347, Length=314, Percent_Identity=30.2547770700637, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI62750349, Length=314, Percent_Identity=30.2547770700637, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI148539870, Length=271, Percent_Identity=30.2583025830258, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI169234807, Length=271, Percent_Identity=30.2583025830258, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI13128864, Length=303, Percent_Identity=29.3729372937294, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI226529806, Length=213, Percent_Identity=31.924882629108, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI217272877, Length=278, Percent_Identity=24.8201438848921, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI209862883, Length=253, Percent_Identity=23.7154150197628, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17508561, Length=313, Percent_Identity=34.8242811501597, Blast_Score=168, Evalue=5e-42,
Organism=Caenorhabditis elegans, GI17534739, Length=318, Percent_Identity=32.0754716981132, Blast_Score=162, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17561978, Length=328, Percent_Identity=31.7073170731707, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI193209491, Length=308, Percent_Identity=28.2467532467532, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI193206283, Length=308, Percent_Identity=29.2207792207792, Blast_Score=101, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17540332, Length=308, Percent_Identity=29.2207792207792, Blast_Score=101, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17540334, Length=308, Percent_Identity=29.2207792207792, Blast_Score=101, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI25154020, Length=295, Percent_Identity=23.0508474576271, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI25154022, Length=295, Percent_Identity=23.0508474576271, Blast_Score=71, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17537347, Length=225, Percent_Identity=26.2222222222222, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI193207430, Length=262, Percent_Identity=26.3358778625954, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6321244, Length=326, Percent_Identity=32.8220858895706, Blast_Score=183, Evalue=5e-47,
Organism=Saccharomyces cerevisiae, GI6323999, Length=310, Percent_Identity=32.258064516129, Blast_Score=161, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6325325, Length=224, Percent_Identity=28.5714285714286, Blast_Score=104, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6324307, Length=338, Percent_Identity=26.3313609467456, Blast_Score=100, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24657891, Length=313, Percent_Identity=34.8242811501597, Blast_Score=175, Evalue=4e-44,
Organism=Drosophila melanogaster, GI24644244, Length=331, Percent_Identity=31.7220543806647, Blast_Score=164, Evalue=7e-41,
Organism=Drosophila melanogaster, GI24642144, Length=290, Percent_Identity=28.2758620689655, Blast_Score=104, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24642142, Length=290, Percent_Identity=28.2758620689655, Blast_Score=104, Evalue=9e-23,
Organism=Drosophila melanogaster, GI24642146, Length=290, Percent_Identity=28.2758620689655, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI281360899, Length=290, Percent_Identity=28.2758620689655, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI281360801, Length=261, Percent_Identity=29.5019157088123, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI281360799, Length=261, Percent_Identity=29.5019157088123, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24641720, Length=261, Percent_Identity=29.5019157088123, Blast_Score=95, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24649807, Length=277, Percent_Identity=25.2707581227437, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003085
- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 43190; Mature: 43190

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDSVFIFSPSYQTYQFHQDHPFNQLRVYVTYDLLNTVGAFEPGETIAPRAATETELELV
CCCCEEEECCCCCEEEECCCCCCCCEEEEEEEEHHHHHCCCCCCCCCCCCCCCCCEEEEE
HTGDYIRAVQLAGAGKLPAAESENYGLGTEDTPVFAGMHEAASLLVGGTLTAADYVMTGK
ECCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHCHHHHHHHHCCCCHHHHHEEEECC
ARHALNLGGGLHHGFRGRASGFCVYNDSSVVIRYLQKKYHAKVLYIDTDAHHGDGVQFTF
CHHEEECCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCEEEEEEECCCCCCCCEEEEE
YDDPSVCTVSIHETGRYLFPGTGQVQERGHGEGYGYAFNIPLDAFTEDESFLDSYRTAVS
ECCCCEEEEEEECCCCEECCCCCCHHHCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHH
EIAEFFKPDVILSQNGADAHYYDPLTHLCTTMKIYEEIPKLAHELAHTYCSGRWIAVGGG
HHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCC
GYDIWRVVPRAWARIWLEMKGMEPEEKMPEKWLKKWGKQASVRLPANWSDPEDLYPPIPR
CHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHCCCCCCC
KTEITEKNAQTVAKALYPIRSAQRTT
CCCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKDSVFIFSPSYQTYQFHQDHPFNQLRVYVTYDLLNTVGAFEPGETIAPRAATETELELV
CCCCEEEECCCCCEEEECCCCCCCCEEEEEEEEHHHHHCCCCCCCCCCCCCCCCCEEEEE
HTGDYIRAVQLAGAGKLPAAESENYGLGTEDTPVFAGMHEAASLLVGGTLTAADYVMTGK
ECCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHCHHHHHHHHCCCCHHHHHEEEECC
ARHALNLGGGLHHGFRGRASGFCVYNDSSVVIRYLQKKYHAKVLYIDTDAHHGDGVQFTF
CHHEEECCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCEEEEEEECCCCCCCCEEEEE
YDDPSVCTVSIHETGRYLFPGTGQVQERGHGEGYGYAFNIPLDAFTEDESFLDSYRTAVS
ECCCCEEEEEEECCCCEECCCCCCHHHCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHH
EIAEFFKPDVILSQNGADAHYYDPLTHLCTTMKIYEEIPKLAHELAHTYCSGRWIAVGGG
HHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCC
GYDIWRVVPRAWARIWLEMKGMEPEEKMPEKWLKKWGKQASVRLPANWSDPEDLYPPIPR
CHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHCCCCCCC
KTEITEKNAQTVAKALYPIRSAQRTT
CCCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7934817; 9387221; 9384377 [H]