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The map label for this gene is rnhC

Identifier: 52786740

GI number: 52786740

Start: 2891589

End: 2892530

Strand: Direct

Name: rnhC

Synonym: BLi03009

Alternate gene names: 52786740

Gene position: 2891589-2892530 (Clockwise)

Preceding gene: 52786726

Following gene: 52786741

Centisome position: 68.48

GC content: 50.53

Gene sequence:

>942_bases
GTGTCACATTCTGTTTTAAAAGTTCCCCCGTCTGTTATTGAACGGATGCAAAGCCACTACGGGCCTGACATTACTTCACT
TTCCGTACAGGGCGCAGTTTTCCAAGCCAAACCCCAAGGGTGCACCATTACAGCATACCGGTCGGGGAAGGTGCTGTTCC
AAGGAAAAAACGCGGAAAAGGAAGCGGAGCGCTGGACGGCGGATGCTGAAACACCGGCTCCCAAAAAGCCCGCATCGAAA
AAAAGCATCCCGTCCGTCTATCAGCCGCCTGAAGGCATCGGTTCCATGTCTGTGATCGGCTCCGATGAAGTCGGGACAGG
CGATTATTTCGGCCCGATCACCGTCGCGTGCGTATACGCTGACAAGGCGAAGCTTCCGCTGTTAAAAGAACTCGGTGTTA
AAGACTCGAAAAACTTAAAAGATCCGCAAATCGTTCAGATCGCGCGCGACTTAATCAAGACAGTCCCTTACAGCCTGCTC
GTTTTAAGAAACGAAAAGTATAATGAAATGCAGGAAAAAGGGATGAGCCAAGGAAAAATGAAAGCTCTTCTCCACAACCA
GGCGATCGGCAACCTTCTCAAAAAATTGGACGGAACCCGGCCTGAAGCGATTTTAATCGACCAGTTCGCCGAACCGGCCG
TATACTTCAAGCATCTGGCAGGCAAAACCGCCGTCAAAGAACGTACATATTTCAGCACAAAAGCGGAAGGCATCCATCTT
TCAGTTGCAGCAGCCTCGATCATTGCACGCTATTCATTTTTAATGGAAATGGATAAGCTGTCAAAACAAGCCGGCATTAC
GCTTCCGAAAGGAGCGGGCCCGCTCGTCGATGAAGCCGGCGCCAAGCTGATCAAGAAACACGGCGAAGACGCATTGCGGG
TATTCACAAAGCTGCATTTTGCCAATACGCAGAAGGCGAAGCGGATTGCGTCGAAACGGTAA

Upstream 100 bases:

>100_bases
ATGTTTACAGATTGAATGGAAAGACGAGCCCTCCGCTGTTATGATACACTTATGAAAACAATGATTTAGCGTATTTAAAG
CTAATAAAGGAGATTAGAAC

Downstream 100 bases:

>100_bases
GCGGTGCGGACTAGGCTGGATAAGCGGGTCCGTTGCAACTAGACCCGCATATTTCACTAAAACATTAACAATAAATGAAA
AATAAGGATTGAAAATTCAA

Product: ribonuclease HIII

Products: NA

Alternate protein names: RNase HIII

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MSHSVLKVPPSVIERMQSHYGPDITSLSVQGAVFQAKPQGCTITAYRSGKVLFQGKNAEKEAERWTADAETPAPKKPASK
KSIPSVYQPPEGIGSMSVIGSDEVGTGDYFGPITVACVYADKAKLPLLKELGVKDSKNLKDPQIVQIARDLIKTVPYSLL
VLRNEKYNEMQEKGMSQGKMKALLHNQAIGNLLKKLDGTRPEAILIDQFAEPAVYFKHLAGKTAVKERTYFSTKAEGIHL
SVAAASIIARYSFLMEMDKLSKQAGITLPKGAGPLVDEAGAKLIKKHGEDALRVFTKLHFANTQKAKRIASKR

Sequences:

>Translated_313_residues
MSHSVLKVPPSVIERMQSHYGPDITSLSVQGAVFQAKPQGCTITAYRSGKVLFQGKNAEKEAERWTADAETPAPKKPASK
KSIPSVYQPPEGIGSMSVIGSDEVGTGDYFGPITVACVYADKAKLPLLKELGVKDSKNLKDPQIVQIARDLIKTVPYSLL
VLRNEKYNEMQEKGMSQGKMKALLHNQAIGNLLKKLDGTRPEAILIDQFAEPAVYFKHLAGKTAVKERTYFSTKAEGIHL
SVAAASIIARYSFLMEMDKLSKQAGITLPKGAGPLVDEAGAKLIKKHGEDALRVFTKLHFANTQKAKRIASKR
>Mature_312_residues
SHSVLKVPPSVIERMQSHYGPDITSLSVQGAVFQAKPQGCTITAYRSGKVLFQGKNAEKEAERWTADAETPAPKKPASKK
SIPSVYQPPEGIGSMSVIGSDEVGTGDYFGPITVACVYADKAKLPLLKELGVKDSKNLKDPQIVQIARDLIKTVPYSLLV
LRNEKYNEMQEKGMSQGKMKALLHNQAIGNLLKKLDGTRPEAILIDQFAEPAVYFKHLAGKTAVKERTYFSTKAEGIHLS
VAAASIIARYSFLMEMDKLSKQAGITLPKGAGPLVDEAGAKLIKKHGEDALRVFTKLHFANTQKAKRIASKR

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG1039

COG function: function code L; Ribonuclease HIII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family. RnhC subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH3_BACLD (Q65GD8)

Other databases:

- EMBL:   AE017333
- EMBL:   CP000002
- RefSeq:   YP_080154.1
- RefSeq:   YP_092569.1
- ProteinModelPortal:   Q65GD8
- SMR:   Q65GD8
- STRING:   Q65GD8
- EnsemblBacteria:   EBBACT00000054372
- EnsemblBacteria:   EBBACT00000061802
- GeneID:   3028735
- GeneID:   3098545
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi03009
- KEGG:   bli:BL00302
- NMPDR:   fig|279010.5.peg.3358
- eggNOG:   COG1039
- GeneTree:   EBGT00050000000939
- HOGENOM:   HBG288559
- OMA:   ASIIARY
- ProtClustDB:   PRK00996
- BioCyc:   BLIC279010-1:BLI03009-MONOMER
- BioCyc:   BLIC279010:BL00302-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00053
- InterPro:   IPR001352
- InterPro:   IPR004641
- InterPro:   IPR012337
- PIRSF:   PIRSF037748
- TIGRFAMs:   TIGR00716

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 34148; Mature: 34017

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHSVLKVPPSVIERMQSHYGPDITSLSVQGAVFQAKPQGCTITAYRSGKVLFQGKNAEK
CCCCCEECCHHHHHHHHHHCCCCCEEEEECCEEEEECCCCCEEEEEECCEEEEECCCCHH
EAERWTADAETPAPKKPASKKSIPSVYQPPEGIGSMSVIGSDEVGTGDYFGPITVACVYA
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCEEEEEEEC
DKAKLPLLKELGVKDSKNLKDPQIVQIARDLIKTVPYSLLVLRNEKYNEMQEKGMSQGKM
CCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHCCCCHHHH
KALLHNQAIGNLLKKLDGTRPEAILIDQFAEPAVYFKHLAGKTAVKERTYFSTKAEGIHL
HHHHHHHHHHHHHHHHCCCCCCEEEEHHHCCHHHHHHHHHCHHHHHHHHHHCCCCCCEEE
SVAAASIIARYSFLMEMDKLSKQAGITLPKGAGPLVDEAGAKLIKKHGEDALRVFTKLHF
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHH
ANTQKAKRIASKR
HCHHHHHHHHCCC
>Mature Secondary Structure 
SHSVLKVPPSVIERMQSHYGPDITSLSVQGAVFQAKPQGCTITAYRSGKVLFQGKNAEK
CCCCEECCHHHHHHHHHHCCCCCEEEEECCEEEEECCCCCEEEEEECCEEEEECCCCHH
EAERWTADAETPAPKKPASKKSIPSVYQPPEGIGSMSVIGSDEVGTGDYFGPITVACVYA
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCEEEEEEEC
DKAKLPLLKELGVKDSKNLKDPQIVQIARDLIKTVPYSLLVLRNEKYNEMQEKGMSQGKM
CCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHCCCCHHHH
KALLHNQAIGNLLKKLDGTRPEAILIDQFAEPAVYFKHLAGKTAVKERTYFSTKAEGIHL
HHHHHHHHHHHHHHHHCCCCCCEEEEHHHCCHHHHHHHHHCHHHHHHHHHHCCCCCCEEE
SVAAASIIARYSFLMEMDKLSKQAGITLPKGAGPLVDEAGAKLIKKHGEDALRVFTKLHF
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHH
ANTQKAKRIASKR
HCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA