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The map label for this gene is holA [H]

Identifier: 52786483

GI number: 52786483

Start: 2644295

End: 2645359

Strand: Reverse

Name: holA [H]

Synonym: BLi02748

Alternate gene names: 52786483

Gene position: 2645359-2644295 (Counterclockwise)

Preceding gene: 52786485

Following gene: 52786481

Centisome position: 62.65

GC content: 46.67

Gene sequence:

>1065_bases
ATGAAAGAGGGGAAAGTGCAGATGACGGTATTTGATGTTTGGAAAAGCTTGAAAAAAGGCGACATTCATCCCGTTTATTG
CTTGTACGGGAAAGAGACGCATCTTCTGCAGGAGACGGTTCAAAGGATCAGACAAGCCGTTGTTGATGAAGAGACGAAAG
ACTTTAACTTCTCGATATTTGATCTGGAAGAAGACGCGCTCGATCTTGCCGTGGAGGATGCGGAAACCTTTCCGTTTATG
GGGGAAAGGCGTCTTGTCGTGGCGAAAAACCCGGCGTTTTTAACAGCTGAAAAAAAGAAGGATAAGCTTGAGCATAATCT
CGGTGTACTGGAAGCTTACATTACGCAGCCGGCACCTTATTCCGTGTTTGTTTTGCTTGCGCCTTATGAAAAGCTCGATG
AACGGAAAAAGCTGACCAAGCTCCTGAAAAAGCATGCGCACATGGTGGAAGCGAAGGAATTAACCGCCAAAGAAACGGCT
GACTTTATCGCAGGCCTCGCGAAGTCGGAAGGCAAACAAATCGAACCGGAAGCGGCGGAGGAGCTTGTCCTGTTATGTCA
TGCAAGTCTGTCAGCCATTGCCCAGGAGGTTAAAAAGCTCAGTACATATACCGGTGACCGCGGAGAGATCACCATAGAGG
ATGTCAGAAAGCTTGTAGCGAGAGGGCTTGAACAAAATATTTTCGAACTGATCAATAAGGTCGTCAATCGGAAACGTACA
GAAGCGCTGCAGATTTTCTACGATCTATTAAAGCAAAATGAAGAGCCGATTAAAATGATGGCGCTGATTGCTAATCAGTT
CAGGCTGCTGATGCAGACCAAATATTTTTCTGACCAGGGATACGGACAAAAGCAAATCGCCTCAAACCTTAAAGTGCACC
CGTTCAGGGTGAAGCTGGCGATCGAGCAGGCGAGGCTTTTTTCAGAGCAGGAGCTTAGGAACATTATCGAGCAGCTCGCC
GTGATGGATTATGAAATGAAGACAGGCAAAAAAGACAAGCAGCTCCTGCTTGAACTGTTTTTGCTGAAGCTGCTGCAGCC
TCATGAAAAAAACGGCCTCCTTTAA

Upstream 100 bases:

>100_bases
CCCGGGGGTTTATGGAAGGCGTTTATTATAAATGAGAGAGCGGGTGACTCCGCTTCTCTCTTTACTAATTGCAAAACACG
CTTTAGGATAGAAAGGAAGG

Downstream 100 bases:

>100_bases
AGAGAGCCGTTTTTTTCATCCTTCACGCAAGCAAAAAAGCTTGGCATAGCCAAGCTTTCTATTATGCAGAAAGTCCGTTC
ACTTTTTTCGCTAGGTTTGA

Product: DNA polymerase III subunit delta

Products: diphosphate; DNAn+1

Alternate protein names: NA

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MKEGKVQMTVFDVWKSLKKGDIHPVYCLYGKETHLLQETVQRIRQAVVDEETKDFNFSIFDLEEDALDLAVEDAETFPFM
GERRLVVAKNPAFLTAEKKKDKLEHNLGVLEAYITQPAPYSVFVLLAPYEKLDERKKLTKLLKKHAHMVEAKELTAKETA
DFIAGLAKSEGKQIEPEAAEELVLLCHASLSAIAQEVKKLSTYTGDRGEITIEDVRKLVARGLEQNIFELINKVVNRKRT
EALQIFYDLLKQNEEPIKMMALIANQFRLLMQTKYFSDQGYGQKQIASNLKVHPFRVKLAIEQARLFSEQELRNIIEQLA
VMDYEMKTGKKDKQLLLELFLLKLLQPHEKNGLL

Sequences:

>Translated_354_residues
MKEGKVQMTVFDVWKSLKKGDIHPVYCLYGKETHLLQETVQRIRQAVVDEETKDFNFSIFDLEEDALDLAVEDAETFPFM
GERRLVVAKNPAFLTAEKKKDKLEHNLGVLEAYITQPAPYSVFVLLAPYEKLDERKKLTKLLKKHAHMVEAKELTAKETA
DFIAGLAKSEGKQIEPEAAEELVLLCHASLSAIAQEVKKLSTYTGDRGEITIEDVRKLVARGLEQNIFELINKVVNRKRT
EALQIFYDLLKQNEEPIKMMALIANQFRLLMQTKYFSDQGYGQKQIASNLKVHPFRVKLAIEQARLFSEQELRNIIEQLA
VMDYEMKTGKKDKQLLLELFLLKLLQPHEKNGLL
>Mature_354_residues
MKEGKVQMTVFDVWKSLKKGDIHPVYCLYGKETHLLQETVQRIRQAVVDEETKDFNFSIFDLEEDALDLAVEDAETFPFM
GERRLVVAKNPAFLTAEKKKDKLEHNLGVLEAYITQPAPYSVFVLLAPYEKLDERKKLTKLLKKHAHMVEAKELTAKETA
DFIAGLAKSEGKQIEPEAAEELVLLCHASLSAIAQEVKKLSTYTGDRGEITIEDVRKLVARGLEQNIFELINKVVNRKRT
EALQIFYDLLKQNEEPIKMMALIANQFRLLMQTKYFSDQGYGQKQIASNLKVHPFRVKLAIEQARLFSEQELRNIIEQLA
VMDYEMKTGKKDKQLLLELFLLKLLQPHEKNGLL

Specific function: Unknown

COG id: COG1466

COG function: function code L; DNA polymerase III, delta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008921
- InterPro:   IPR010372
- InterPro:   IPR005790 [H]

Pfam domain/function: PF06144 DNA_pol3_delta [H]

EC number: 2.7.7.7

Molecular weight: Translated: 40723; Mature: 40723

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEGKVQMTVFDVWKSLKKGDIHPVYCLYGKETHLLQETVQRIRQAVVDEETKDFNFSIF
CCCCCEEHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
DLEEDALDLAVEDAETFPFMGERRLVVAKNPAFLTAEKKKDKLEHNLGVLEAYITQPAPY
ECCHHHHHHHHHCCCCCCCCCCCEEEEECCCCEEECHHHHHHHHHHHHHHHHHHCCCCCC
SVFVLLAPYEKLDERKKLTKLLKKHAHMVEAKELTAKETADFIAGLAKSEGKQIEPEAAE
EEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
ELVLLCHASLSAIAQEVKKLSTYTGDRGEITIEDVRKLVARGLEQNIFELINKVVNRKRT
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EALQIFYDLLKQNEEPIKMMALIANQFRLLMQTKYFSDQGYGQKQIASNLKVHPFRVKLA
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCEEEEEEH
IEQARLFSEQELRNIIEQLAVMDYEMKTGKKDKQLLLELFLLKLLQPHEKNGLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKEGKVQMTVFDVWKSLKKGDIHPVYCLYGKETHLLQETVQRIRQAVVDEETKDFNFSIF
CCCCCEEHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
DLEEDALDLAVEDAETFPFMGERRLVVAKNPAFLTAEKKKDKLEHNLGVLEAYITQPAPY
ECCHHHHHHHHHCCCCCCCCCCCEEEEECCCCEEECHHHHHHHHHHHHHHHHHHCCCCCC
SVFVLLAPYEKLDERKKLTKLLKKHAHMVEAKELTAKETADFIAGLAKSEGKQIEPEAAE
EEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
ELVLLCHASLSAIAQEVKKLSTYTGDRGEITIEDVRKLVARGLEQNIFELINKVVNRKRT
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EALQIFYDLLKQNEEPIKMMALIANQFRLLMQTKYFSDQGYGQKQIASNLKVHPFRVKLA
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCEEEEEEH
IEQARLFSEQELRNIIEQLAVMDYEMKTGKKDKQLLLELFLLKLLQPHEKNGLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: deoxynucleoside triphosphate; DNAn

Specific reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]