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The map label for this gene is prmA

Identifier: 52786472

GI number: 52786472

Start: 2631904

End: 2632839

Strand: Reverse

Name: prmA

Synonym: BLi02737

Alternate gene names: 52786472

Gene position: 2632839-2631904 (Counterclockwise)

Preceding gene: 52786473

Following gene: 52786471

Centisome position: 62.35

GC content: 46.37

Gene sequence:

>936_bases
ATGAAATGGTCCGAAATCTGCATTCACACGACACATGAAGCGGTTGAGCCCATCTCGAATATTTTGCATGAAGCTGGTGC
GAGTGGAGTAGTGATTGAAGATCCGCTTGATTTAATTAAAGAGCGTGAGAATGTATACGGAGAAATCTACCAGCTCGATC
CCAATGATTATCCTGATGAAGGAGTCATCATCAAAGCGTATCTTCCGATCAACAGCTTTTTGGGGGAGACCGTAGAAGGA
ATCAAAGAAACGATCAATAATCTGCTGCTGTATGATATTGACCTTGGACGCAACAAAATCACCATCAGCGAGGTTAACGA
AGAAGAATGGGCGACAGCATGGAAAAAATATTATCATCCCGTGAAAATTTCCGAGAAGTTTACGATTGTTCCGACTTGGG
AAGAGTACACACCGGTTCATACGGATGAACTCATCATCGAGATGGACCCGGGAATGGCGTTTGGAACAGGCACCCACCCG
ACAACCGTCCTTTGCATACAGGCGCTTGAAAGGTATGTGAAAGAAGGGGATTCGGTCGTGGACGTCGGAACGGGAACCGG
CATTTTGAGCATTGCTTCAGCCATGCTTCGCGCCAAACAGGTTGAAGGATATGATCTCGATCCTGTAGCCGTTGAAAGCG
CCCGCTTGAACTCCAAGCTCAATAAAGTCAGCGATCATATCGAGATTAAGCAAAATAATCTGCTTGACGGCGTCGAAGGC
GAAAAAGACATCATCGTCGCCAATATCCTGGCCGAGGTCATCTTGCGCTTTACGGATCAAGCATACAGCCTGTTGAAAGA
CGGCGGCTATTTCATCACTTCGGGGATCATCCAGCAGAAAAAACAGGAAGTCAAAGATGCACTGGTGAAAGAAGGCTTTA
CGATCGTTGAGGTTCTTTCAATGGAGGACTGGGTCAGCATCATCGCTAAAAAATAA

Upstream 100 bases:

>100_bases
AAGTGAGCGGAAATATGCCGGATGAACAGGAAATGAGTTTTTTCGATAAAGTAAAGCGCGCCTTTAAAGGCGATTAATGA
TTGGATGAGGAGTTGGTAGT

Downstream 100 bases:

>100_bases
TCGTTAGTAGGTGTGACAAGCGTATGCAACGATATTTTATCGAACAATCAAAACAAGAGGTCACAGCCGCACCCGCATTC
TCGATCAAAGGCGAAGACGT

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MKWSEICIHTTHEAVEPISNILHEAGASGVVIEDPLDLIKERENVYGEIYQLDPNDYPDEGVIIKAYLPINSFLGETVEG
IKETINNLLLYDIDLGRNKITISEVNEEEWATAWKKYYHPVKISEKFTIVPTWEEYTPVHTDELIIEMDPGMAFGTGTHP
TTVLCIQALERYVKEGDSVVDVGTGTGILSIASAMLRAKQVEGYDLDPVAVESARLNSKLNKVSDHIEIKQNNLLDGVEG
EKDIIVANILAEVILRFTDQAYSLLKDGGYFITSGIIQQKKQEVKDALVKEGFTIVEVLSMEDWVSIIAKK

Sequences:

>Translated_311_residues
MKWSEICIHTTHEAVEPISNILHEAGASGVVIEDPLDLIKERENVYGEIYQLDPNDYPDEGVIIKAYLPINSFLGETVEG
IKETINNLLLYDIDLGRNKITISEVNEEEWATAWKKYYHPVKISEKFTIVPTWEEYTPVHTDELIIEMDPGMAFGTGTHP
TTVLCIQALERYVKEGDSVVDVGTGTGILSIASAMLRAKQVEGYDLDPVAVESARLNSKLNKVSDHIEIKQNNLLDGVEG
EKDIIVANILAEVILRFTDQAYSLLKDGGYFITSGIIQQKKQEVKDALVKEGFTIVEVLSMEDWVSIIAKK
>Mature_311_residues
MKWSEICIHTTHEAVEPISNILHEAGASGVVIEDPLDLIKERENVYGEIYQLDPNDYPDEGVIIKAYLPINSFLGETVEG
IKETINNLLLYDIDLGRNKITISEVNEEEWATAWKKYYHPVKISEKFTIVPTWEEYTPVHTDELIIEMDPGMAFGTGTHP
TTVLCIQALERYVKEGDSVVDVGTGTGILSIASAMLRAKQVEGYDLDPVAVESARLNSKLNKVSDHIEIKQNNLLDGVEG
EKDIIVANILAEVILRFTDQAYSLLKDGGYFITSGIIQQKKQEVKDALVKEGFTIVEVLSMEDWVSIIAKK

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=313, Percent_Identity=30.6709265175719, Blast_Score=119, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_BACLD (Q65H56)

Other databases:

- EMBL:   CP000002
- EMBL:   AE017333
- RefSeq:   YP_079884.1
- RefSeq:   YP_092301.1
- HSSP:   Q84BQ9
- ProteinModelPortal:   Q65H56
- SMR:   Q65H56
- STRING:   Q65H56
- EnsemblBacteria:   EBBACT00000057414
- EnsemblBacteria:   EBBACT00000061971
- GeneID:   3029139
- GeneID:   3097773
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi02737
- KEGG:   bli:BL02099
- NMPDR:   fig|279010.5.peg.3008
- eggNOG:   COG2264
- GeneTree:   EBGT00050000002784
- HOGENOM:   HBG584653
- OMA:   IELNPGM
- ProtClustDB:   PRK00517
- BioCyc:   BLIC279010-1:BLI02737-MONOMER
- BioCyc:   BLIC279010:BL02099-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 34767; Mature: 34767

Theoretical pI: Translated: 4.32; Mature: 4.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKWSEICIHTTHEAVEPISNILHEAGASGVVIEDPLDLIKERENVYGEIYQLDPNDYPDE
CCCHHEEEECCHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHCEEEEEECCCCCCCC
GVIIKAYLPINSFLGETVEGIKETINNLLLYDIDLGRNKITISEVNEEEWATAWKKYYHP
CEEEEEECCHHHHHHHHHHHHHHHHHCEEEEEEECCCCEEEEEECCHHHHHHHHHHHCCC
VKISEKFTIVPTWEEYTPVHTDELIIEMDPGMAFGTGTHPTTVLCIQALERYVKEGDSVV
EEECCCEEEEECHHHCCCCCCCCEEEEECCCCEECCCCCHHHHHHHHHHHHHHHCCCCEE
DVGTGTGILSIASAMLRAKQVEGYDLDPVAVESARLNSKLNKVSDHIEIKQNNLLDGVEG
EECCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCC
EKDIIVANILAEVILRFTDQAYSLLKDGGYFITSGIIQQKKQEVKDALVKEGFTIVEVLS
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHCCCCEEHHHH
MEDWVSIIAKK
HHHHHHHHCCC
>Mature Secondary Structure
MKWSEICIHTTHEAVEPISNILHEAGASGVVIEDPLDLIKERENVYGEIYQLDPNDYPDE
CCCHHEEEECCHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHCEEEEEECCCCCCCC
GVIIKAYLPINSFLGETVEGIKETINNLLLYDIDLGRNKITISEVNEEEWATAWKKYYHP
CEEEEEECCHHHHHHHHHHHHHHHHHCEEEEEEECCCCEEEEEECCHHHHHHHHHHHCCC
VKISEKFTIVPTWEEYTPVHTDELIIEMDPGMAFGTGTHPTTVLCIQALERYVKEGDSVV
EEECCCEEEEECHHHCCCCCCCCEEEEECCCCEECCCCCHHHHHHHHHHHHHHHCCCCEE
DVGTGTGILSIASAMLRAKQVEGYDLDPVAVESARLNSKLNKVSDHIEIKQNNLLDGVEG
EECCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCC
EKDIIVANILAEVILRFTDQAYSLLKDGGYFITSGIIQQKKQEVKDALVKEGFTIVEVLS
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHCCCCEEHHHH
MEDWVSIIAKK
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA