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The map label for this gene is hfq [H]

Identifier: 52785720

GI number: 52785720

Start: 1919705

End: 1919926

Strand: Direct

Name: hfq [H]

Synonym: BLi01962

Alternate gene names: 52785720

Gene position: 1919705-1919926 (Clockwise)

Preceding gene: 52785719

Following gene: 52785721

Centisome position: 45.46

GC content: 37.84

Gene sequence:

>222_bases
ATGAAATCGATAAATATTCAAGATCAGTTTTTGAATCAGATTCGGAAAGAAAATACATTTGTCACGGTCTTTTTACTGAA
TGGATTTCAGCTGCGCGGACAAGTAAAAGGATTTGACAACTTTACAGTGTTGATTGAATCGGAAGGAAAGCAGCAGCTCA
TATACAAACACGCCATTTCTACGTTTGCACCGCAAAAAAACGTTCAGCTCGAACTGGAATAG

Upstream 100 bases:

>100_bases
ATATCGAGCAGAAAAAACAGGAAATTTTCACTTACATAGCAGGAAAGCTCGAACTTTAATCGAAACAATATGGTATAGAG
AAACAAGGAGGACCAGAAAC

Downstream 100 bases:

>100_bases
CGATTCACGGACTAAAAGACCATGCCTTGCATGGTTTTTTCAGATTGCCTGACAAAATCCTGAAACAGGTTACTGTTTTG
GGATTTTTCGTTTTCAAAGC

Product: RNA-binding protein Hfq

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 73; Mature: 73

Protein sequence:

>73_residues
MKSINIQDQFLNQIRKENTFVTVFLLNGFQLRGQVKGFDNFTVLIESEGKQQLIYKHAISTFAPQKNVQLELE

Sequences:

>Translated_73_residues
MKSINIQDQFLNQIRKENTFVTVFLLNGFQLRGQVKGFDNFTVLIESEGKQQLIYKHAISTFAPQKNVQLELE
>Mature_73_residues
MKSINIQDQFLNQIRKENTFVTVFLLNGFQLRGQVKGFDNFTVLIESEGKQQLIYKHAISTFAPQKNVQLELE

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs [H]

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family [H]

Homologues:

Organism=Escherichia coli, GI1790614, Length=67, Percent_Identity=43.2835820895522, Blast_Score=67, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163 [H]

Pfam domain/function: PF01423 LSM [H]

EC number: NA

Molecular weight: Translated: 8488; Mature: 8488

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSINIQDQFLNQIRKENTFVTVFLLNGFQLRGQVKGFDNFTVLIESEGKQQLIYKHAIS
CCCCCCHHHHHHHHHCCCCEEEEEEECCEEEEEEECCCCCEEEEEECCCCHHHHHHHHHH
TFAPQKNVQLELE
HCCCCCCEEEEEC
>Mature Secondary Structure
MKSINIQDQFLNQIRKENTFVTVFLLNGFQLRGQVKGFDNFTVLIESEGKQQLIYKHAIS
CCCCCCHHHHHHHHHCCCCEEEEEEECCEEEEEEECCCCCEEEEEECCCCHHHHHHHHHH
TFAPQKNVQLELE
HCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA