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The map label for this gene is pgsA [H]

Identifier: 52785674

GI number: 52785674

Start: 1875515

End: 1876096

Strand: Direct

Name: pgsA [H]

Synonym: BLi01916

Alternate gene names: 52785674

Gene position: 1875515-1876096 (Clockwise)

Preceding gene: 52785673

Following gene: 52785675

Centisome position: 44.42

GC content: 48.28

Gene sequence:

>582_bases
ATGTTTAATTTACCGAATAAAATCACGCTTTCTAGAATCGCATTAATTCCTGTTTTTATGGTCATCATGCTTGTGCCGTT
TCAGTGGGGGGCTGTCTCCTTCGGCAGCGAGTCGATTCCGGTCACCCATTTGATCGGCGCACTGCTGTTTATTTTCGCTT
CGGTCACCGATTGGGTTGACGGCTATTATGCAAGAAAGCTGAACCTTGTAACAAACTTTGGGAAATTCCTTGACCCGCTT
GCAGACAAGCTGCTCGTGTCTTCCGCTTTGATTATTCTGGTGCATTACCATCTTGCTCCGGCCTGGATGGCCATTGTCAT
TATCAGCCGGGAATTTGCCGTAACGGGACTGCGGCTCGTCCTTGCGGGAACGGGGGAAGTCGTCGCAGCCAACATGCTTG
GAAAAGTGAAAACATGGGCCCAGATCATCGCGATCTCTGCCCTTTTGCTTCACAATCTCCCATTTGAGCTTGTATCCTTC
CCGTTCGGCTCTCTTGCTTTATGGGTGGCTGTCTTTTTCACAGTCGTATCCGGCTGGGATTATTTCGCTAAAAACTGGGA
TGCTTTAAAAACATCGAACTAA

Upstream 100 bases:

>100_bases
GATTCAAAATAAAAAGGAGGAAAAGTCATCTTAATTGCACAGATGACTTTTTCTTGCGTTCATCATCATTAGGAAAACAT
ACATATATGGAGGAACCTTT

Downstream 100 bases:

>100_bases
ACGTAGGGAAGTGGAAACAATGAAGTTGGAAAGAAAAGCGGAAATTATCGCTGTCGGCTCTGAGCTTCTGCTCGGACAAA
TCGTTAATACAAATGCTCAG

Product: hypothetical protein

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MFNLPNKITLSRIALIPVFMVIMLVPFQWGAVSFGSESIPVTHLIGALLFIFASVTDWVDGYYARKLNLVTNFGKFLDPL
ADKLLVSSALIILVHYHLAPAWMAIVIISREFAVTGLRLVLAGTGEVVAANMLGKVKTWAQIIAISALLLHNLPFELVSF
PFGSLALWVAVFFTVVSGWDYFAKNWDALKTSN

Sequences:

>Translated_193_residues
MFNLPNKITLSRIALIPVFMVIMLVPFQWGAVSFGSESIPVTHLIGALLFIFASVTDWVDGYYARKLNLVTNFGKFLDPL
ADKLLVSSALIILVHYHLAPAWMAIVIISREFAVTGLRLVLAGTGEVVAANMLGKVKTWAQIIAISALLLHNLPFELVSF
PFGSLALWVAVFFTVVSGWDYFAKNWDALKTSN
>Mature_193_residues
MFNLPNKITLSRIALIPVFMVIMLVPFQWGAVSFGSESIPVTHLIGALLFIFASVTDWVDGYYARKLNLVTNFGKFLDPL
ADKLLVSSALIILVHYHLAPAWMAIVIISREFAVTGLRLVLAGTGEVVAANMLGKVKTWAQIIAISALLLHNLPFELVSF
PFGSLALWVAVFFTVVSGWDYFAKNWDALKTSN

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=155, Percent_Identity=40, Blast_Score=102, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 21300; Mature: 21300

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNLPNKITLSRIALIPVFMVIMLVPFQWGAVSFGSESIPVTHLIGALLFIFASVTDWVD
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
GYYARKLNLVTNFGKFLDPLADKLLVSSALIILVHYHLAPAWMAIVIISREFAVTGLRLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
LAGTGEVVAANMLGKVKTWAQIIAISALLLHNLPFELVSFPFGSLALWVAVFFTVVSGWD
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHCHH
YFAKNWDALKTSN
HHHCCCCCCCCCC
>Mature Secondary Structure
MFNLPNKITLSRIALIPVFMVIMLVPFQWGAVSFGSESIPVTHLIGALLFIFASVTDWVD
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
GYYARKLNLVTNFGKFLDPLADKLLVSSALIILVHYHLAPAWMAIVIISREFAVTGLRLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
LAGTGEVVAANMLGKVKTWAQIIAISALLLHNLPFELVSFPFGSLALWVAVFFTVVSGWD
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHCHH
YFAKNWDALKTSN
HHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7750561; 9384377 [H]