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The map label for this gene is hslU

Identifier: 52785595

GI number: 52785595

Start: 1793910

End: 1795313

Strand: Direct

Name: hslU

Synonym: BLi01836

Alternate gene names: 52785595

Gene position: 1793910-1795313 (Clockwise)

Preceding gene: 52785594

Following gene: 52785596

Centisome position: 42.48

GC content: 48.01

Gene sequence:

>1404_bases
ATGGAAAAAAAGCCGCTGACTCCTAGGCAGATCGTCGAAAGGCTTGATCAATACATCGTCGGCCAGCTCGATGCGAAAAA
AGCGGTCGCCGTGGCATTGAGGAACCGCTACAGAAGAAGTCTTCTTGATGAAAAACTGCGCGAAGAAATCGTTCCGAAAA
ACATATTGATGATGGGCCCGACAGGTGTGGGAAAAACCGAGATTGCAAGACGAATCGCGAAACTCGTCGGCGCTCCGTTC
GTCAAAATCGAAGCGACGAAGTTCACGGAAGTCGGTTATGTGGGCAGAGATGTGGAGTCGATGGTCAGGGATCTTGTGGA
AACGTCAGTCCGCCTCGTCAAAGAGGAAAAAATGAACGAAGTGAAAGGCATCGCTGAAGAAAACGCAAATAAACGCCTCG
TCCGCCTGCTTGTACCGGGAAGAAAAAAACAGACAGGTGCGAAAAATCCTTTTGAAATGCTGTTTGGCGGAAATCAGGAT
CAAGAAACTGGTGAAGCGGAAAAGCAAGAAGACGCGGATATCGAAAACAACCGAAAACGGATTGCGCATCAGCTTGCTCT
CGGCGAACTTGAAGACCATTATGTCACCGTTGAGGTGGAGGAGCAGCAGCCGTCCATGTTTGATATGCTCCAAGGCTCGG
GTATGGAACAGATGGGCATGAACATGCAGGATGCGCTCAGCAGCCTGATGCCGAAAAAGAAAAAGCGCCGCAAGCTTACG
GTCAGGGAAGCGCGAAAAGTGCTGACGAATGAAGAAGCGGCAAAGCTCATCGATATGGACGAAGCTGCCCAGGAAGCTGT
CCAGAGAGCCGAACAGTCGGGAATCATCTTTATCGATGAGATCGATAAAATCGCCAAAAAGAGCGGTGCTTCTTCATCGG
CAGACGTCTCAAGAGAAGGCGTGCAGCGCGATATTCTTCCGATTGTTGAAGGATCTACCGTCATGACAAAGTACGGTGCG
GTCAAAACGGATCACGTTCTGTTCATTGCTGCAGGTGCATTCCACATGGCGAAGCCTTCAGATCTAATTCCTGAGCTGCA
GGGGCGCTTTCCAATACGCGTTGAGCTTCAAAAGCTGAGCATCGATGACTTTGTGAAAATTTTAACTGAGCCTGACAACG
CTCTTCTTAAGCAGTATAAGGCTTTATTGAAGACGGAAGGTATATCTCTTGAATTTTCTGACGATGCTATTCGTAAGATT
GCAGAAGTGGCTTATCATGTGAACCAGGACACAGACAATATTGGGGCGAGAAGGCTTCACACCATTTTGGAACGTCTTTT
GGAAGAACTGTCATTCGAGGCTCCGGATGTGACGATGGAAGAAGTGGTCATCACGCCTCAATATGTTGAAGAAAAGCTCG
GTTCGATCGCTAAGAATAAGGATTTAAGCCAGTTTATTTTATAA

Upstream 100 bases:

>100_bases
GCGATTGCGAGGGCTTCACTTGAAACCGCGGGCGAAATCTGTGTGTATACGAACGATCAGATCATTGTAGAAGAACTTGA
ATAGAAAGGATATGAGGCAT

Downstream 100 bases:

>100_bases
ACAATTAAATAAGAGTAATTTAGGAGGATCAATTTATTATGGCTTTATTACAAAAAACAAGAAAGATTAATGCAATGCTG
CAAAATGCGGCAGGGAAGCC

Product: ATP-dependent protease ATP-binding subunit HslU

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MEKKPLTPRQIVERLDQYIVGQLDAKKAVAVALRNRYRRSLLDEKLREEIVPKNILMMGPTGVGKTEIARRIAKLVGAPF
VKIEATKFTEVGYVGRDVESMVRDLVETSVRLVKEEKMNEVKGIAEENANKRLVRLLVPGRKKQTGAKNPFEMLFGGNQD
QETGEAEKQEDADIENNRKRIAHQLALGELEDHYVTVEVEEQQPSMFDMLQGSGMEQMGMNMQDALSSLMPKKKKRRKLT
VREARKVLTNEEAAKLIDMDEAAQEAVQRAEQSGIIFIDEIDKIAKKSGASSSADVSREGVQRDILPIVEGSTVMTKYGA
VKTDHVLFIAAGAFHMAKPSDLIPELQGRFPIRVELQKLSIDDFVKILTEPDNALLKQYKALLKTEGISLEFSDDAIRKI
AEVAYHVNQDTDNIGARRLHTILERLLEELSFEAPDVTMEEVVITPQYVEEKLGSIAKNKDLSQFIL

Sequences:

>Translated_467_residues
MEKKPLTPRQIVERLDQYIVGQLDAKKAVAVALRNRYRRSLLDEKLREEIVPKNILMMGPTGVGKTEIARRIAKLVGAPF
VKIEATKFTEVGYVGRDVESMVRDLVETSVRLVKEEKMNEVKGIAEENANKRLVRLLVPGRKKQTGAKNPFEMLFGGNQD
QETGEAEKQEDADIENNRKRIAHQLALGELEDHYVTVEVEEQQPSMFDMLQGSGMEQMGMNMQDALSSLMPKKKKRRKLT
VREARKVLTNEEAAKLIDMDEAAQEAVQRAEQSGIIFIDEIDKIAKKSGASSSADVSREGVQRDILPIVEGSTVMTKYGA
VKTDHVLFIAAGAFHMAKPSDLIPELQGRFPIRVELQKLSIDDFVKILTEPDNALLKQYKALLKTEGISLEFSDDAIRKI
AEVAYHVNQDTDNIGARRLHTILERLLEELSFEAPDVTMEEVVITPQYVEEKLGSIAKNKDLSQFIL
>Mature_467_residues
MEKKPLTPRQIVERLDQYIVGQLDAKKAVAVALRNRYRRSLLDEKLREEIVPKNILMMGPTGVGKTEIARRIAKLVGAPF
VKIEATKFTEVGYVGRDVESMVRDLVETSVRLVKEEKMNEVKGIAEENANKRLVRLLVPGRKKQTGAKNPFEMLFGGNQD
QETGEAEKQEDADIENNRKRIAHQLALGELEDHYVTVEVEEQQPSMFDMLQGSGMEQMGMNMQDALSSLMPKKKKRRKLT
VREARKVLTNEEAAKLIDMDEAAQEAVQRAEQSGIIFIDEIDKIAKKSGASSSADVSREGVQRDILPIVEGSTVMTKYGA
VKTDHVLFIAAGAFHMAKPSDLIPELQGRFPIRVELQKLSIDDFVKILTEPDNALLKQYKALLKTEGISLEFSDDAIRKI
AEVAYHVNQDTDNIGARRLHTILERLLEELSFEAPDVTMEEVVITPQYVEEKLGSIAKNKDLSQFIL

Specific function: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity

COG id: COG1220

COG function: function code O; ATP-dependent protease HslVU (ClpYQ), ATPase subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family. HslU subfamily

Homologues:

Organism=Homo sapiens, GI7242140, Length=111, Percent_Identity=38.7387387387387, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1790366, Length=462, Percent_Identity=51.0822510822511, Blast_Score=472, Evalue=1e-134,
Organism=Escherichia coli, GI1786642, Length=232, Percent_Identity=34.4827586206897, Blast_Score=103, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71982905, Length=247, Percent_Identity=31.9838056680162, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI71982908, Length=247, Percent_Identity=31.9838056680162, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI71988663, Length=258, Percent_Identity=26.7441860465116, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6319704, Length=141, Percent_Identity=36.1702127659575, Blast_Score=80, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24648291, Length=253, Percent_Identity=31.6205533596838, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24648289, Length=253, Percent_Identity=31.6205533596838, Blast_Score=108, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CLPY_BACLD (Q65JN3)

Other databases:

- EMBL:   CP000002
- EMBL:   AE017333
- RefSeq:   YP_079009.1
- RefSeq:   YP_091424.1
- HSSP:   P43773
- ProteinModelPortal:   Q65JN3
- SMR:   Q65JN3
- STRING:   Q65JN3
- EnsemblBacteria:   EBBACT00000057738
- EnsemblBacteria:   EBBACT00000060334
- GeneID:   3031008
- GeneID:   3100236
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi01836
- KEGG:   bli:BL01277
- NMPDR:   fig|279010.5.peg.2539
- eggNOG:   COG1220
- GeneTree:   EBGT00050000000359
- HOGENOM:   HBG745965
- OMA:   EASKFTE
- ProtClustDB:   PRK05201
- BioCyc:   BLIC279010-1:BLI01836-MONOMER
- BioCyc:   BLIC279010:BL01277-MONOMER
- HAMAP:   MF_00249
- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR019489
- InterPro:   IPR004491
- PANTHER:   PTHR11262:SF3
- SMART:   SM00382
- TIGRFAMs:   TIGR00390

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF10431 ClpB_D2-small

EC number: NA

Molecular weight: Translated: 52539; Mature: 52539

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: BINDING 20-20 BINDING 279-279 BINDING 345-345 BINDING 417-417

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKKPLTPRQIVERLDQYIVGQLDAKKAVAVALRNRYRRSLLDEKLREEIVPKNILMMGP
CCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECC
TGVGKTEIARRIAKLVGAPFVKIEATKFTEVGYVGRDVESMVRDLVETSVRLVKEEKMNE
CCCCHHHHHHHHHHHHCCCCEEEEECHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VKGIAEENANKRLVRLLVPGRKKQTGAKNPFEMLFGGNQDQETGEAEKQEDADIENNRKR
HHHHHHCCCCHHEEEEECCCCCCCCCCCCCHHHHCCCCCCCCCCCHHHHHCCCHHHHHHH
IAHQLALGELEDHYVTVEVEEQQPSMFDMLQGSGMEQMGMNMQDALSSLMPKKKKRRKLT
HHHHHHHCCCCCCEEEEEECCCCCHHHHHHHCCCHHHHCCCHHHHHHHHCCCHHHHHHHH
VREARKVLTNEEAAKLIDMDEAAQEAVQRAEQSGIIFIDEIDKIAKKSGASSSADVSREG
HHHHHHHHCCHHHHHHHCHHHHHHHHHHHHHHCCEEEEHHHHHHHHHCCCCCCCHHHHHH
VQRDILPIVEGSTVMTKYGAVKTDHVLFIAAGAFHMAKPSDLIPELQGRFPIRVELQKLS
HHHHHHHHCCCCCHHHHCCCCCCCCEEEEEECCHHCCCCHHHHHHHCCCCCEEEEHHHCC
IDDFVKILTEPDNALLKQYKALLKTEGISLEFSDDAIRKIAEVAYHVNQDTDNIGARRLH
HHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHCCCCCHHHHHHHH
TILERLLEELSFEAPDVTMEEVVITPQYVEEKLGSIAKNKDLSQFIL
HHHHHHHHHHCCCCCCCCHHHEEECHHHHHHHHHHHHCCCCHHHHCC
>Mature Secondary Structure
MEKKPLTPRQIVERLDQYIVGQLDAKKAVAVALRNRYRRSLLDEKLREEIVPKNILMMGP
CCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECC
TGVGKTEIARRIAKLVGAPFVKIEATKFTEVGYVGRDVESMVRDLVETSVRLVKEEKMNE
CCCCHHHHHHHHHHHHCCCCEEEEECHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VKGIAEENANKRLVRLLVPGRKKQTGAKNPFEMLFGGNQDQETGEAEKQEDADIENNRKR
HHHHHHCCCCHHEEEEECCCCCCCCCCCCCHHHHCCCCCCCCCCCHHHHHCCCHHHHHHH
IAHQLALGELEDHYVTVEVEEQQPSMFDMLQGSGMEQMGMNMQDALSSLMPKKKKRRKLT
HHHHHHHCCCCCCEEEEEECCCCCHHHHHHHCCCHHHHCCCHHHHHHHHCCCHHHHHHHH
VREARKVLTNEEAAKLIDMDEAAQEAVQRAEQSGIIFIDEIDKIAKKSGASSSADVSREG
HHHHHHHHCCHHHHHHHCHHHHHHHHHHHHHHCCEEEEHHHHHHHHHCCCCCCCHHHHHH
VQRDILPIVEGSTVMTKYGAVKTDHVLFIAAGAFHMAKPSDLIPELQGRFPIRVELQKLS
HHHHHHHHCCCCCHHHHCCCCCCCCEEEEEECCHHCCCCHHHHHHHCCCCCEEEEHHHCC
IDDFVKILTEPDNALLKQYKALLKTEGISLEFSDDAIRKIAEVAYHVNQDTDNIGARRLH
HHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHCCCCCHHHHHHHH
TILERLLEELSFEAPDVTMEEVVITPQYVEEKLGSIAKNKDLSQFIL
HHHHHHHHHHCCCCCCCCHHHEEECHHHHHHHHHHHHCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA