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The map label for this gene is coaD

Identifier: 52785479

GI number: 52785479

Start: 1674430

End: 1674924

Strand: Direct

Name: coaD

Synonym: BLi01719

Alternate gene names: 52785479

Gene position: 1674430-1674924 (Clockwise)

Preceding gene: 52785478

Following gene: 52785481

Centisome position: 39.65

GC content: 45.25

Gene sequence:

>495_bases
ATGGCTAGCATTGCCGTTTGTCCCGGAAGTTTTGATCCGGTGACTTTTGGACATTTGGATATCATCAGGCGCGGGGCGAA
AGTGTTTGATAAAGTTTATGTATGCGTTTTGAACAATTCTTCGAAGAAGCCGCTGTTTACAGTGGAAGAACGCTGTGGGC
TGCTTCGCGAAGTGACGCAGGATATCCCGAATGTGCAAGTGGAATCTTTTCAGGGGCTTTTGATTGATTATGCAAAGAGC
AAGCAGGCAAACGTCATCCTGCGGGGGCTTAGAGCGGTATCTGACTTTGAATACGAGATGCAGGGAACCTCGATGAACAA
AGTGCTCGATGAAAATATTGAAACGTTTTTTATGATGACGAATAACCAATACTCGTTCCTCAGTTCAAGCATTGTCAAAG
AAGTGGCAAAATATAAAGGTTCAGTCGCAGAACTCGTGCCGGAAGCGGTCGAGGCTGCACTTGAAAAAAAGTTTGCAAAA
AATGAGCGGCCGTAA

Upstream 100 bases:

>100_bases
GAAGTCATGCTGCCGGATGCGGCGGGCGGACTTCAGCTTGCCCGGCAGGAAATATACGGCTTAACAGGCGTGACCATATA
CAGAAAGAGAGGGAATGGGG

Downstream 100 bases:

>100_bases
CCGGCTGCTCATTTTTTAACAGGGGCGTAAGATTTGGCATAAAGAATGATATAGATGAGAAGGGTGCCGATTGTTAGGAG
CGGACCGATCTCTGCTAAAG

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MASIAVCPGSFDPVTFGHLDIIRRGAKVFDKVYVCVLNNSSKKPLFTVEERCGLLREVTQDIPNVQVESFQGLLIDYAKS
KQANVILRGLRAVSDFEYEMQGTSMNKVLDENIETFFMMTNNQYSFLSSSIVKEVAKYKGSVAELVPEAVEAALEKKFAK
NERP

Sequences:

>Translated_164_residues
MASIAVCPGSFDPVTFGHLDIIRRGAKVFDKVYVCVLNNSSKKPLFTVEERCGLLREVTQDIPNVQVESFQGLLIDYAKS
KQANVILRGLRAVSDFEYEMQGTSMNKVLDENIETFFMMTNNQYSFLSSSIVKEVAKYKGSVAELVPEAVEAALEKKFAK
NERP
>Mature_163_residues
ASIAVCPGSFDPVTFGHLDIIRRGAKVFDKVYVCVLNNSSKKPLFTVEERCGLLREVTQDIPNVQVESFQGLLIDYAKSK
QANVILRGLRAVSDFEYEMQGTSMNKVLDENIETFFMMTNNQYSFLSSSIVKEVAKYKGSVAELVPEAVEAALEKKFAKN
ERP

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=159, Percent_Identity=45.9119496855346, Blast_Score=166, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_BACLD (Q65JZ9)

Other databases:

- EMBL:   CP000002
- EMBL:   AE017333
- RefSeq:   YP_078896.1
- RefSeq:   YP_091308.1
- HSSP:   O34797
- ProteinModelPortal:   Q65JZ9
- SMR:   Q65JZ9
- STRING:   Q65JZ9
- EnsemblBacteria:   EBBACT00000056700
- EnsemblBacteria:   EBBACT00000061467
- GeneID:   3030863
- GeneID:   3100218
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi01719
- KEGG:   bli:BL02991
- NMPDR:   fig|279010.5.peg.1567
- eggNOG:   COG0669
- GeneTree:   EBGT00050000002538
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- ProtClustDB:   PRK00168
- BioCyc:   BLIC279010-1:BLI01719-MONOMER
- BioCyc:   BLIC279010:BL02991-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 18368; Mature: 18237

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASIAVCPGSFDPVTFGHLDIIRRGAKVFDKVYVCVLNNSSKKPLFTVEERCGLLREVTQ
CCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHEEEEECCCCCCCEEEHHHHHHHHHHHHH
DIPNVQVESFQGLLIDYAKSKQANVILRGLRAVSDFEYEMQGTSMNKVLDENIETFFMMT
HCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHCCCCHHHHHHHCCCEEEEEEE
NNQYSFLSSSIVKEVAKYKGSVAELVPEAVEAALEKKFAKNERP
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ASIAVCPGSFDPVTFGHLDIIRRGAKVFDKVYVCVLNNSSKKPLFTVEERCGLLREVTQ
CCEEECCCCCCCCCHHHHHHHHHHHHHHHHHEEEEECCCCCCCEEEHHHHHHHHHHHHH
DIPNVQVESFQGLLIDYAKSKQANVILRGLRAVSDFEYEMQGTSMNKVLDENIETFFMMT
HCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHCCCCHHHHHHHCCCEEEEEEE
NNQYSFLSSSIVKEVAKYKGSVAELVPEAVEAALEKKFAKNERP
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA