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The map label for this gene is kinC [H]

Identifier: 52785425

GI number: 52785425

Start: 1623467

End: 1624804

Strand: Direct

Name: kinC [H]

Synonym: BLi01665

Alternate gene names: 52785425

Gene position: 1623467-1624804 (Clockwise)

Preceding gene: 52785424

Following gene: 52785426

Centisome position: 38.45

GC content: 45.59

Gene sequence:

>1338_bases
ATGAAAAGATATCAAGGACGAATCATTGCAACCGTGCTGGCAATGACTTTTATCATGTTTTGGAATTTTTTATTCTATGG
GGTGTTGGGAAATAAAATCAATTGGACGGTTGATCTGCTGTTTACGCTGGTGACATTAATCAGCGTTTGGTGGCTCACAC
TTTATATCGATGAGTCAAATCAGCTTGTCTATAAATTGAAGGAAAGCGAAAAGAAATATAAAGAGCTTTCCTCAGAAACC
AACCGCATAATGGATAATCTTCAGGAAATCGTCTTTCAAACGGACCGGATAGGATACATTACATTTCTGAATCAGGCGTG
GACAACCCTGACCGGATACAGTGTCGAAGAGAGCCTTGGAACGATGTACAACGATTATTTTGACCATGAAGAACGGATCT
CGAATCACCTGATCGCCCAGTTGAAGAACAAGGAGCCCGAAGGCAGGATCGAGGTGCTCTACCATCGCAAAGACGGGAGC
AAGTTCTGGGGCGAAGTTCACTATAAACTTTATTATAAAAACGGTCAATTTACGGGCAGCTTGGGGACGCTGACTGATGT
GACAGAACGGAAAAAAGCGGAGATGGAACTGTTTAAGTCGAATCAGCGGCTGGCCATGCAGTCTCAAAAGCTGGCGATGG
CCGGGCAGCTCGCAGCGGGGATCGCTCACGAAGTCAGGAACCCGCTGACATCTGTAAACGGATTTTTGCAGCTGATGAAA
GCGGAATATCCTGACCGGAAAGATTACTTTGACATTATTTTCTCAGAGATTAAACGAATCGATTCTGTGCTCGGAGAACT
GCTTGTGCTGGCCAAACCGCACCAGGTTCAATTTAAAAAGATCAAAATCAATTCGGTTCTTCAGCAAGTGGCAACGCTTC
TTGAGACGAACGCCGTGCTTTCCCACATTAAGATCGAAAAAGCGTTTCAGCACGGGGAGGAGTGGGAAATAAACGGTGAT
GAAAATCAAATCAAACAGGTATTCATCAATTTAATTAAAAACGGGATAGAAGCGATGCCTGACGGCGGTAAAATTACGAT
TTCCTCAAAGGCAGAAGGAGACTGTGTGAAAATCAGCATCAAAGACGAAGGCGGGGGCATTTCCCAAGCCGACTTGGCAA
AGCTCGGGGAGCCTTTCTTCTCAACGAAAGAAGAAGGGACAGGTCTTGGGCTGACAATTTGCCTGAATATCATCGGCGCC
CACAACGGAGAAATGAAAATCGACAGCAAATTGGGCGAGGGAAGCACATTCCACATTTTGCTTCCGGTCGATAAAGGTGC
GGCGTCCGAAGAGAACGACATTCAGCAAGGATGCTGCAGCCGCGCAACTATAAAATAA

Upstream 100 bases:

>100_bases
AAATTCAGCCATAGAGACGATAAATACTTCGAACAATCCTCTCAAATGTGGTGTAAAGAATGTTACAATTGACTGAGAAA
TACAAGTGGCAGGTGGGGGT

Downstream 100 bases:

>100_bases
AAGAGGAAAAATTCCACTTCATATGATAGAATTTGTTCAAGATTGACCCATGGAGGAATTACCGATGAAAAAAGAATTTG
CAGTAATTGGACTCGGCCGG

Product: KinC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MKRYQGRIIATVLAMTFIMFWNFLFYGVLGNKINWTVDLLFTLVTLISVWWLTLYIDESNQLVYKLKESEKKYKELSSET
NRIMDNLQEIVFQTDRIGYITFLNQAWTTLTGYSVEESLGTMYNDYFDHEERISNHLIAQLKNKEPEGRIEVLYHRKDGS
KFWGEVHYKLYYKNGQFTGSLGTLTDVTERKKAEMELFKSNQRLAMQSQKLAMAGQLAAGIAHEVRNPLTSVNGFLQLMK
AEYPDRKDYFDIIFSEIKRIDSVLGELLVLAKPHQVQFKKIKINSVLQQVATLLETNAVLSHIKIEKAFQHGEEWEINGD
ENQIKQVFINLIKNGIEAMPDGGKITISSKAEGDCVKISIKDEGGGISQADLAKLGEPFFSTKEEGTGLGLTICLNIIGA
HNGEMKIDSKLGEGSTFHILLPVDKGAASEENDIQQGCCSRATIK

Sequences:

>Translated_445_residues
MKRYQGRIIATVLAMTFIMFWNFLFYGVLGNKINWTVDLLFTLVTLISVWWLTLYIDESNQLVYKLKESEKKYKELSSET
NRIMDNLQEIVFQTDRIGYITFLNQAWTTLTGYSVEESLGTMYNDYFDHEERISNHLIAQLKNKEPEGRIEVLYHRKDGS
KFWGEVHYKLYYKNGQFTGSLGTLTDVTERKKAEMELFKSNQRLAMQSQKLAMAGQLAAGIAHEVRNPLTSVNGFLQLMK
AEYPDRKDYFDIIFSEIKRIDSVLGELLVLAKPHQVQFKKIKINSVLQQVATLLETNAVLSHIKIEKAFQHGEEWEINGD
ENQIKQVFINLIKNGIEAMPDGGKITISSKAEGDCVKISIKDEGGGISQADLAKLGEPFFSTKEEGTGLGLTICLNIIGA
HNGEMKIDSKLGEGSTFHILLPVDKGAASEENDIQQGCCSRATIK
>Mature_445_residues
MKRYQGRIIATVLAMTFIMFWNFLFYGVLGNKINWTVDLLFTLVTLISVWWLTLYIDESNQLVYKLKESEKKYKELSSET
NRIMDNLQEIVFQTDRIGYITFLNQAWTTLTGYSVEESLGTMYNDYFDHEERISNHLIAQLKNKEPEGRIEVLYHRKDGS
KFWGEVHYKLYYKNGQFTGSLGTLTDVTERKKAEMELFKSNQRLAMQSQKLAMAGQLAAGIAHEVRNPLTSVNGFLQLMK
AEYPDRKDYFDIIFSEIKRIDSVLGELLVLAKPHQVQFKKIKINSVLQQVATLLETNAVLSHIKIEKAFQHGEEWEINGD
ENQIKQVFINLIKNGIEAMPDGGKITISSKAEGDCVKISIKDEGGGISQADLAKLGEPFFSTKEEGTGLGLTICLNIIGA
HNGEMKIDSKLGEGSTFHILLPVDKGAASEENDIQQGCCSRATIK

Specific function: Phosphorylates the sporulation-regulatory protein spo0A [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=371, Percent_Identity=29.9191374663073, Blast_Score=193, Evalue=2e-50,
Organism=Escherichia coli, GI1790436, Length=222, Percent_Identity=34.6846846846847, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI145693157, Length=270, Percent_Identity=27.037037037037, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790300, Length=250, Percent_Identity=28, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1786600, Length=217, Percent_Identity=26.2672811059908, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1788713, Length=225, Percent_Identity=27.5555555555556, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI87081816, Length=263, Percent_Identity=27.7566539923954, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1790346, Length=239, Percent_Identity=28.4518828451883, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1786783, Length=217, Percent_Identity=24.8847926267281, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788393, Length=238, Percent_Identity=25.2100840336134, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1789149, Length=267, Percent_Identity=23.9700374531835, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI48994928, Length=401, Percent_Identity=21.9451371571072, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1790861, Length=219, Percent_Identity=22.3744292237443, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI87082128, Length=251, Percent_Identity=24.3027888446215, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50439; Mature: 50439

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRYQGRIIATVLAMTFIMFWNFLFYGVLGNKINWTVDLLFTLVTLISVWWLTLYIDESN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEEEEECCC
QLVYKLKESEKKYKELSSETNRIMDNLQEIVFQTDRIGYITFLNQAWTTLTGYSVEESLG
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCHHHHHH
TMYNDYFDHEERISNHLIAQLKNKEPEGRIEVLYHRKDGSKFWGEVHYKLYYKNGQFTGS
HHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCEEEEEEEEEECCEEECC
LGTLTDVTERKKAEMELFKSNQRLAMQSQKLAMAGQLAAGIAHEVRNPLTSVNGFLQLMK
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEYPDRKDYFDIIFSEIKRIDSVLGELLVLAKPHQVQFKKIKINSVLQQVATLLETNAVL
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHH
SHIKIEKAFQHGEEWEINGDENQIKQVFINLIKNGIEAMPDGGKITISSKAEGDCVKISI
HHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEE
KDEGGGISQADLAKLGEPFFSTKEEGTGLGLTICLNIIGAHNGEMKIDSKLGEGSTFHIL
ECCCCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCEEEEE
LPVDKGAASEENDIQQGCCSRATIK
EEECCCCCCCCHHHHHHHCCCCCCC
>Mature Secondary Structure
MKRYQGRIIATVLAMTFIMFWNFLFYGVLGNKINWTVDLLFTLVTLISVWWLTLYIDESN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEEEEECCC
QLVYKLKESEKKYKELSSETNRIMDNLQEIVFQTDRIGYITFLNQAWTTLTGYSVEESLG
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCHHHHHH
TMYNDYFDHEERISNHLIAQLKNKEPEGRIEVLYHRKDGSKFWGEVHYKLYYKNGQFTGS
HHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCEEEEEEEEEECCEEECC
LGTLTDVTERKKAEMELFKSNQRLAMQSQKLAMAGQLAAGIAHEVRNPLTSVNGFLQLMK
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEYPDRKDYFDIIFSEIKRIDSVLGELLVLAKPHQVQFKKIKINSVLQQVATLLETNAVL
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHH
SHIKIEKAFQHGEEWEINGDENQIKQVFINLIKNGIEAMPDGGKITISSKAEGDCVKISI
HHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEE
KDEGGGISQADLAKLGEPFFSTKEEGTGLGLTICLNIIGAHNGEMKIDSKLGEGSTFHIL
ECCCCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCEEEEE
LPVDKGAASEENDIQQGCCSRATIK
EEECCCCCCCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8002615; 8002614; 8969500; 9384377 [H]