| Definition | Bacillus licheniformis ATCC 14580, complete genome. |
|---|---|
| Accession | NC_006322 |
| Length | 4,222,645 |
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The map label for this gene is ykuF [H]
Identifier: 52785382
GI number: 52785382
Start: 1585763
End: 1586527
Strand: Direct
Name: ykuF [H]
Synonym: BLi01620
Alternate gene names: 52785382
Gene position: 1585763-1586527 (Clockwise)
Preceding gene: 52785376
Following gene: 52785383
Centisome position: 37.55
GC content: 55.03
Gene sequence:
>765_bases ATGGACAGAAAAGTTGTAATCGTGACCGGCGGGTCGAGCGGAATGGGAAAAGCGATCGCCAAAAAGCAGGCTGAAGAAGG ATGGAATGTGATGATTACGGGCAGAACACAAGAAACGCTCGAAGCGGCCAAAGAAGAAATTGAAACTTTTGCCGGGCAGG TGGCCGTATGCCGGATGGATGTCCGGTCTGTTGAAGATGTGGAACAGATGATCACAGAGGCGGCAGGACGGTTTGGCACG ATCGACGCTTTGGTTAACAATGCCGCAGGCAACTTTATCTGCCCGGCTGAAAAACTATCGGTCAACGGCTGGAAGGCGGT CATCGATATCGTGCTGAACGGCACATTTTATTGCAGCCAAGCAGCCGGCCGCTACTGGATCAAGGAAAAGAAACGCGGCC AGATTTTAAATATGGTCGCGACGTATGCATGGGGCGCCGGTGCCGGTGTCGTTCACTCCGCGGCGGCAAAAGCAGGCGTT CTGTCGCTGACAAGGACGCTTGCCGTCGAGTGGGGAAGTGCATACGGGATTAGGTGCAACGCCATTGCGCCCGGTCCGAT CGAGAGGACGGGCGGAGCCGAAAAATTATTTGAATCGGAAGAAGCCGCGCACGCGACAATCAAAAGCGTTCCGCTCAAAA GGCTGGGCACCCCTGAAGAAATCGCGGGACTCGCCGCATTTTTGCTTTCTGAGCAGGCGGGATATGTCAACGGGGAGTGT GTGACGATGGACGGAGGTCAATGGCTGAATCCCCGTCCGTTTTAG
Upstream 100 bases:
>100_bases AAGCCATTTTAGGACAGTCCGCATGTTTTGTTAATTTTTTTTAATTTATATGATAAACTATCAATTGAATGAATACTCAT TCATAACAAGGGGGATGGAT
Downstream 100 bases:
>100_bases ATTTCAAATTCAAAGGTGCGAGCCGGTATGGTATAATCAGACAAAGATTAGAAGCAGGTGATATGCCATGTTGGATCCAC TCGATATTTTAACGAACATT
Product: short chain dehydrogenase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 254; Mature: 254
Protein sequence:
>254_residues MDRKVVIVTGGSSGMGKAIAKKQAEEGWNVMITGRTQETLEAAKEEIETFAGQVAVCRMDVRSVEDVEQMITEAAGRFGT IDALVNNAAGNFICPAEKLSVNGWKAVIDIVLNGTFYCSQAAGRYWIKEKKRGQILNMVATYAWGAGAGVVHSAAAKAGV LSLTRTLAVEWGSAYGIRCNAIAPGPIERTGGAEKLFESEEAAHATIKSVPLKRLGTPEEIAGLAAFLLSEQAGYVNGEC VTMDGGQWLNPRPF
Sequences:
>Translated_254_residues MDRKVVIVTGGSSGMGKAIAKKQAEEGWNVMITGRTQETLEAAKEEIETFAGQVAVCRMDVRSVEDVEQMITEAAGRFGT IDALVNNAAGNFICPAEKLSVNGWKAVIDIVLNGTFYCSQAAGRYWIKEKKRGQILNMVATYAWGAGAGVVHSAAAKAGV LSLTRTLAVEWGSAYGIRCNAIAPGPIERTGGAEKLFESEEAAHATIKSVPLKRLGTPEEIAGLAAFLLSEQAGYVNGEC VTMDGGQWLNPRPF >Mature_254_residues MDRKVVIVTGGSSGMGKAIAKKQAEEGWNVMITGRTQETLEAAKEEIETFAGQVAVCRMDVRSVEDVEQMITEAAGRFGT IDALVNNAAGNFICPAEKLSVNGWKAVIDIVLNGTFYCSQAAGRYWIKEKKRGQILNMVATYAWGAGAGVVHSAAAKAGV LSLTRTLAVEWGSAYGIRCNAIAPGPIERTGGAEKLFESEEAAHATIKSVPLKRLGTPEEIAGLAAFLLSEQAGYVNGEC VTMDGGQWLNPRPF
Specific function: Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3- enoyl-CoA
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily [H]
Homologues:
Organism=Homo sapiens, GI19923817, Length=255, Percent_Identity=38.4313725490196, Blast_Score=170, Evalue=9e-43, Organism=Homo sapiens, GI4503301, Length=222, Percent_Identity=40.5405405405405, Blast_Score=162, Evalue=3e-40, Organism=Homo sapiens, GI10190704, Length=248, Percent_Identity=38.7096774193548, Blast_Score=157, Evalue=1e-38, Organism=Homo sapiens, GI32483357, Length=244, Percent_Identity=30.327868852459, Blast_Score=108, Evalue=6e-24, Organism=Homo sapiens, GI15277342, Length=259, Percent_Identity=30.1158301158301, Blast_Score=103, Evalue=2e-22, Organism=Homo sapiens, GI5031737, Length=251, Percent_Identity=29.0836653386454, Blast_Score=95, Evalue=5e-20, Organism=Homo sapiens, GI126723750, Length=253, Percent_Identity=28.4584980237154, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI59889578, Length=196, Percent_Identity=33.1632653061224, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI40254992, Length=249, Percent_Identity=29.3172690763052, Blast_Score=81, Evalue=8e-16, Organism=Homo sapiens, GI7705925, Length=243, Percent_Identity=26.3374485596708, Blast_Score=78, Evalue=9e-15, Organism=Homo sapiens, GI4504505, Length=193, Percent_Identity=34.1968911917098, Blast_Score=78, Evalue=9e-15, Organism=Homo sapiens, GI40254986, Length=140, Percent_Identity=33.5714285714286, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI4758504, Length=264, Percent_Identity=27.6515151515151, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI66933014, Length=255, Percent_Identity=29.4117647058824, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI33667109, Length=193, Percent_Identity=30.0518134715026, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI4503817, Length=200, Percent_Identity=31.5, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI83715985, Length=262, Percent_Identity=25.5725190839695, Blast_Score=65, Evalue=7e-11, Organism=Escherichia coli, GI1789208, Length=249, Percent_Identity=30.1204819277108, Blast_Score=123, Evalue=1e-29, Organism=Escherichia coli, GI1788459, Length=253, Percent_Identity=29.6442687747036, Blast_Score=113, Evalue=1e-26, Organism=Escherichia coli, GI1787335, Length=246, Percent_Identity=32.1138211382114, Blast_Score=107, Evalue=1e-24, Organism=Escherichia coli, GI87082160, Length=246, Percent_Identity=31.7073170731707, Blast_Score=106, Evalue=2e-24, Organism=Escherichia coli, GI1790717, Length=243, Percent_Identity=29.6296296296296, Blast_Score=101, Evalue=5e-23, Organism=Escherichia coli, GI1787905, Length=252, Percent_Identity=30.1587301587302, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI87082100, Length=257, Percent_Identity=32.295719844358, Blast_Score=99, Evalue=2e-22, Organism=Escherichia coli, GI2367175, Length=255, Percent_Identity=31.7647058823529, Blast_Score=88, Evalue=7e-19, Organism=Escherichia coli, GI1787820, Length=244, Percent_Identity=29.5081967213115, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI1789378, Length=255, Percent_Identity=27.4509803921569, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1786812, Length=254, Percent_Identity=28.3464566929134, Blast_Score=75, Evalue=5e-15, Organism=Escherichia coli, GI2367365, Length=243, Percent_Identity=30.4526748971193, Blast_Score=74, Evalue=8e-15, Organism=Escherichia coli, GI1787526, Length=238, Percent_Identity=23.9495798319328, Blast_Score=62, Evalue=2e-11, Organism=Escherichia coli, GI1789057, Length=260, Percent_Identity=22.3076923076923, Blast_Score=61, Evalue=9e-11, Organism=Caenorhabditis elegans, GI17536025, Length=248, Percent_Identity=41.9354838709677, Blast_Score=170, Evalue=8e-43, Organism=Caenorhabditis elegans, GI17561272, Length=237, Percent_Identity=42.1940928270042, Blast_Score=166, Evalue=1e-41, Organism=Caenorhabditis elegans, GI17536651, Length=250, Percent_Identity=39.6, Blast_Score=160, Evalue=5e-40, Organism=Caenorhabditis elegans, GI17562910, Length=262, Percent_Identity=30.5343511450382, Blast_Score=109, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17560150, Length=260, Percent_Identity=31.1538461538462, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17562904, Length=265, Percent_Identity=29.811320754717, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17561402, Length=252, Percent_Identity=30.5555555555556, Blast_Score=95, Evalue=4e-20, Organism=Caenorhabditis elegans, GI17562906, Length=262, Percent_Identity=28.2442748091603, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI17562908, Length=268, Percent_Identity=28.3582089552239, Blast_Score=93, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17559104, Length=267, Percent_Identity=31.8352059925094, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17555706, Length=248, Percent_Identity=31.4516129032258, Blast_Score=91, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17563726, Length=266, Percent_Identity=30.8270676691729, Blast_Score=91, Evalue=7e-19, Organism=Caenorhabditis elegans, GI17531453, Length=263, Percent_Identity=29.6577946768061, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17560676, Length=246, Percent_Identity=26.4227642276423, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17560332, Length=264, Percent_Identity=30.6818181818182, Blast_Score=88, Evalue=3e-18, Organism=Caenorhabditis elegans, GI71994600, Length=262, Percent_Identity=26.7175572519084, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17562990, Length=260, Percent_Identity=30, Blast_Score=87, Evalue=8e-18, Organism=Caenorhabditis elegans, GI17551412, Length=269, Percent_Identity=28.2527881040892, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI193204405, Length=269, Percent_Identity=28.996282527881, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17560220, Length=268, Percent_Identity=27.9850746268657, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI72000259, Length=283, Percent_Identity=30.0353356890459, Blast_Score=84, Evalue=9e-17, Organism=Caenorhabditis elegans, GI71994604, Length=261, Percent_Identity=26.8199233716475, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI25147288, Length=250, Percent_Identity=29.2, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17538486, Length=267, Percent_Identity=27.7153558052434, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17538480, Length=265, Percent_Identity=29.0566037735849, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17544670, Length=267, Percent_Identity=25.0936329588015, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI71982365, Length=142, Percent_Identity=32.3943661971831, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17565030, Length=269, Percent_Identity=28.2527881040892, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17538182, Length=256, Percent_Identity=31.25, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI115534694, Length=246, Percent_Identity=26.4227642276423, Blast_Score=70, Evalue=8e-13, Organism=Caenorhabditis elegans, GI17568967, Length=193, Percent_Identity=29.0155440414508, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI17508651, Length=256, Percent_Identity=28.125, Blast_Score=67, Evalue=9e-12, Organism=Caenorhabditis elegans, GI17558628, Length=142, Percent_Identity=30.9859154929577, Blast_Score=64, Evalue=6e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=249, Percent_Identity=36.144578313253, Blast_Score=144, Evalue=1e-35, Organism=Saccharomyces cerevisiae, GI6322861, Length=270, Percent_Identity=29.6296296296296, Blast_Score=86, Evalue=8e-18, Organism=Drosophila melanogaster, GI21355319, Length=251, Percent_Identity=32.6693227091633, Blast_Score=127, Evalue=7e-30, Organism=Drosophila melanogaster, GI24639444, Length=249, Percent_Identity=33.7349397590361, Blast_Score=115, Evalue=2e-26, Organism=Drosophila melanogaster, GI23397609, Length=261, Percent_Identity=31.8007662835249, Blast_Score=105, Evalue=2e-23, Organism=Drosophila melanogaster, GI21357041, Length=260, Percent_Identity=30.3846153846154, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI24644339, Length=260, Percent_Identity=30, Blast_Score=94, Evalue=8e-20, Organism=Drosophila melanogaster, GI28571526, Length=260, Percent_Identity=30, Blast_Score=92, Evalue=3e-19, Organism=Drosophila melanogaster, GI24643142, Length=246, Percent_Identity=26.4227642276423, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI18859837, Length=197, Percent_Identity=31.9796954314721, Blast_Score=80, Evalue=2e-15, Organism=Drosophila melanogaster, GI17737361, Length=260, Percent_Identity=30.7692307692308, Blast_Score=77, Evalue=8e-15, Organism=Drosophila melanogaster, GI21357673, Length=203, Percent_Identity=29.064039408867, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI24644337, Length=202, Percent_Identity=29.7029702970297, Blast_Score=67, Evalue=1e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.3.1.34 [H]
Molecular weight: Translated: 27013; Mature: 27013
Theoretical pI: Translated: 5.89; Mature: 5.89
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.0 %Cys (Translated Protein) 2.8 %Met (Translated Protein) 4.7 %Cys+Met (Translated Protein) 2.0 %Cys (Mature Protein) 2.8 %Met (Mature Protein) 4.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDRKVVIVTGGSSGMGKAIAKKQAEEGWNVMITGRTQETLEAAKEEIETFAGQVAVCRMD CCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHCCEEEEEHH VRSVEDVEQMITEAAGRFGTIDALVNNAAGNFICPAEKLSVNGWKAVIDIVLNGTFYCSQ HHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCEECCHHHHCCCHHHHHHHHHHCCCEEECC AAGRYWIKEKKRGQILNMVATYAWGAGAGVVHSAAAKAGVLSLTRTLAVEWGSAYGIRCN CCCCHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEC AIAPGPIERTGGAEKLFESEEAAHATIKSVPLKRLGTPEEIAGLAAFLLSEQAGYVNGEC CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHCCCCCCCEE VTMDGGQWLNPRPF EEECCCCCCCCCCC >Mature Secondary Structure MDRKVVIVTGGSSGMGKAIAKKQAEEGWNVMITGRTQETLEAAKEEIETFAGQVAVCRMD CCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHCCEEEEEHH VRSVEDVEQMITEAAGRFGTIDALVNNAAGNFICPAEKLSVNGWKAVIDIVLNGTFYCSQ HHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCEECCHHHHCCCHHHHHHHHHHCCCEEECC AAGRYWIKEKKRGQILNMVATYAWGAGAGVVHSAAAKAGVLSLTRTLAVEWGSAYGIRCN CCCCHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEC AIAPGPIERTGGAEKLFESEEAAHATIKSVPLKRLGTPEEIAGLAAFLLSEQAGYVNGEC CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHCCCCCCCEE VTMDGGQWLNPRPF EEECCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9384377 [H]