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The map label for this gene is clpP1 [H]

Identifier: 52785314

GI number: 52785314

Start: 1519622

End: 1520368

Strand: Direct

Name: clpP1 [H]

Synonym: BLi01550

Alternate gene names: 52785314

Gene position: 1519622-1520368 (Clockwise)

Preceding gene: 52785313

Following gene: 52785315

Centisome position: 35.99

GC content: 47.93

Gene sequence:

>747_bases
GTGAGGACGATAAAGAAGTTCTGGGAAATCAAAGCGGCGAAGAATGACGCTAAAACAGGCGAGATTTACATTTACAGTGA
AATCAGTTCGGCCCAGTTCTGGGGGGACGAAGTGACTACGCAAACTTTCAAGGAGGATTTAGACGGACTTGGCGAAGTAT
CTGCGCTAAATATCTATATTAATTCGCCAGGCGGCTCTGTTTTCGAAGGGAATTCGATCTACAACATCATAAAGCGGCAC
AAAGCCCACGTTAACGTCTACGTCGACGGGCTGGCGGCCTCTATCGCAAGTGTCATCGCAATGTCCGGTGACGCTATTTT
TATGCCTGCAAACGCGATGATGATGATTCATAATCCGTGGACTGTTGCGCAAGGCAATGCGGAAGAACTCCGCAAACAAG
CCGACGACATGGATCGTATTCGCGAAAGTCTTATCGAGGCATATCTCGGAAAAGCAGGCGAAAAACTCAATCGTGATCGT
TTGATCGAACTTATGGACGCAGAAACGTGGCTGACGGCGCAAGAATGTCTCGAATTAGGGCTGTGTGATTCTATCGAAGC
TCCTAGCGCTGCGGTTGCGAAAGTGGATACGCAGTTATTTGCGAAGTACCGGAACACTCCGGAATCGCTTCTTAATCAGA
CGAAAGAGGACGAAAAGCAGGCGGAAAAAGAGCGCCTGTTCCGTGAGCAGCTTATCGCGGAAGCACAAACGAATTTACTA
AAACTTCAAAACGGGGGAATCATTTAA

Upstream 100 bases:

>100_bases
CCAATCGACCAGGTTGCGCAACAGAAAATCACATCGGCTGATGCCCCGACGCCTCCATCGTTAGAAATTAACGAAGATGA
TAACGAGGACTCGAAAGGAG

Downstream 100 bases:

>100_bases
TGGAACTATTTGATCTGAAGGCAAACTTAAACACTGTAGGAACACAATTAGCATCGGTTGAAAAGGAAATCATGAACAAA
GCGGCTGACCCTAACGCTTC

Product: hypothetical protein

Products: NA

Alternate protein names: Endopeptidase Clp 1 [H]

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MRTIKKFWEIKAAKNDAKTGEIYIYSEISSAQFWGDEVTTQTFKEDLDGLGEVSALNIYINSPGGSVFEGNSIYNIIKRH
KAHVNVYVDGLAASIASVIAMSGDAIFMPANAMMMIHNPWTVAQGNAEELRKQADDMDRIRESLIEAYLGKAGEKLNRDR
LIELMDAETWLTAQECLELGLCDSIEAPSAAVAKVDTQLFAKYRNTPESLLNQTKEDEKQAEKERLFREQLIAEAQTNLL
KLQNGGII

Sequences:

>Translated_248_residues
MRTIKKFWEIKAAKNDAKTGEIYIYSEISSAQFWGDEVTTQTFKEDLDGLGEVSALNIYINSPGGSVFEGNSIYNIIKRH
KAHVNVYVDGLAASIASVIAMSGDAIFMPANAMMMIHNPWTVAQGNAEELRKQADDMDRIRESLIEAYLGKAGEKLNRDR
LIELMDAETWLTAQECLELGLCDSIEAPSAAVAKVDTQLFAKYRNTPESLLNQTKEDEKQAEKERLFREQLIAEAQTNLL
KLQNGGII
>Mature_248_residues
MRTIKKFWEIKAAKNDAKTGEIYIYSEISSAQFWGDEVTTQTFKEDLDGLGEVSALNIYINSPGGSVFEGNSIYNIIKRH
KAHVNVYVDGLAASIASVIAMSGDAIFMPANAMMMIHNPWTVAQGNAEELRKQADDMDRIRESLIEAYLGKAGEKLNRDR
LIELMDAETWLTAQECLELGLCDSIEAPSAAVAKVDTQLFAKYRNTPESLLNQTKEDEKQAEKERLFREQLIAEAQTNLL
KLQNGGII

Specific function: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins [H]

COG id: COG0740

COG function: function code OU; Protease subunit of ATP-dependent Clp proteases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S14 family [H]

Homologues:

Organism=Escherichia coli, GI1786641, Length=133, Percent_Identity=31.5789473684211, Blast_Score=65, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17538017, Length=133, Percent_Identity=33.8345864661654, Blast_Score=81, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001907
- InterPro:   IPR018215 [H]

Pfam domain/function: PF00574 CLP_protease [H]

EC number: =3.4.21.92 [H]

Molecular weight: Translated: 27682; Mature: 27682

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTIKKFWEIKAAKNDAKTGEIYIYSEISSAQFWGDEVTTQTFKEDLDGLGEVSALNIYI
CCHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHCCCHHHHHHHHHHHHCCCCEEEEEEEE
NSPGGSVFEGNSIYNIIKRHKAHVNVYVDGLAASIASVIAMSGDAIFMPANAMMMIHNPW
ECCCCCEEECCHHHHHHHHHHCEEEEEEHHHHHHHHHHHHHCCCEEEECCCEEEEEECCC
TVAQGNAEELRKQADDMDRIRESLIEAYLGKAGEKLNRDRLIELMDAETWLTAQECLELG
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHC
LCDSIEAPSAAVAKVDTQLFAKYRNTPESLLNQTKEDEKQAEKERLFREQLIAEAQTNLL
CCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHE
KLQNGGII
EECCCCCC
>Mature Secondary Structure
MRTIKKFWEIKAAKNDAKTGEIYIYSEISSAQFWGDEVTTQTFKEDLDGLGEVSALNIYI
CCHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHCCCHHHHHHHHHHHHCCCCEEEEEEEE
NSPGGSVFEGNSIYNIIKRHKAHVNVYVDGLAASIASVIAMSGDAIFMPANAMMMIHNPW
ECCCCCEEECCHHHHHHHHHHCEEEEEEHHHHHHHHHHHHHCCCEEEECCCEEEEEECCC
TVAQGNAEELRKQADDMDRIRESLIEAYLGKAGEKLNRDRLIELMDAETWLTAQECLELG
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHC
LCDSIEAPSAAVAKVDTQLFAKYRNTPESLLNQTKEDEKQAEKERLFREQLIAEAQTNLL
CCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHE
KLQNGGII
EECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA