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The map label for this gene is ykrY

Identifier: 52785281

GI number: 52785281

Start: 1491103

End: 1492386

Strand: Direct

Name: ykrY

Synonym: BLi01516

Alternate gene names: 52785281

Gene position: 1491103-1492386 (Clockwise)

Preceding gene: 52785280

Following gene: 52785282

Centisome position: 35.31

GC content: 51.01

Gene sequence:

>1284_bases
ATGAGAAAGCCGCTTATCATTTGCGATTTTGACGGAACGATCACAACAAACGACAACATCATCAGCATTATGAAACAATT
TGCTCCAGAAGAATGGACCGCTCTAAAAGACGGGGTTCTGTCCAAGGACATATCGATTCGGGACGGAGTCGGCAGAATGT
TTAATTTGCTTCCGGCCAGCCTGAAAGAAGACATTACGGCATATGTACTGAAACAAGCCGAGACCCGCCCCGGATTTAAA
GAATTTGTTTCTTTCCTGGATGAGAAGGGTCTTCCGTTTTACGTTGTGAGCGGAGGGATGGATTTTTTCGTCTATCCTCT
GCTTGAAGGAATTGTCGGAAAGGACCGCATTTATTGCAACGAGGCCGCTTTCACCAGCCGCAATATCGAGATCCGCTGGC
CGTATCCGTGTGACGGCGGCTGCGGAAATGACTGCGGCTGCTGCAAGCCTTCCATCATCCGCCGGCTGAAAGGCCGGGAC
GATTTCGTTGTCATGATCGGGGACTCTGTTACAGATGTTGAAGCTGCCAAATGTTCCGATTTATGCATCGCGCGCGACTA
TTTGCTGCGGGAATGTGAAGAGCTCGGCTTGAAGCATGCGGCATTCGGCGATTTCCGCGATGTAAGGCGAATACTCGAAG
AGACCGCGGAGGTGAAAGAATGGATGTCTGAGCAAAAACGGCAGGAACTAGCCGAGGTAAAAAAAGAGCTTGCGGAAAGG
GATTGGTTCCCGGCGACAAGCGGTAATCTGTCAATCAAAGTATCAGAAGACCCGCTGCGGTTTCTCATCACAGCAAGCGG
AAAAGATAAAAGAAAAGAGACCGAGGAGGATTTTCTCCTGGCGGACGAAGAGGGGAGGCCGGCGGAGACCGGACACGCGC
TGAAGCCGTCGGCGGAGACGCTGCTGCACACCTATGTCTATCAACACACAAACGCCGGCTGCTGTCTTCACGTCCACACG
GTTGACAACAATGTCATCTCAGAGCTTTATGCAAAAGAAAAGCAAGTGACATTCAGGGGCCAGGAAATCATAAAGGCGCT
CGGACTTTGGGAGGAGCACGCGGAGGTCACGGTCCCGATTATCGAAAACAGCGCTCATATTCCTGATTTGGCGGCGGATT
TTGCCGGGCACCTTTCAGGCGATTCAGGCGCAGTGCTGATTCGCAGCCACGGCATTACTGTCTGGGGAAAAACGGCATTT
GAGGCAAAGCGGATGCTTGAAGCATATGAATTCTTGTTCAGCTGGCATTTAAAGCTGAAAGCTTTGCAGGCTTATCACGT
TTAA

Upstream 100 bases:

>100_bases
TTGATGCCGTCTTAGAAGCGGAGCCTGTCGAAGAGAAAGCAAAGCGCTCTCCCGATTTGAAGCTCGCCCTTGAAAAATGG
GGAAGGGTTGAGGTCTCTGT

Downstream 100 bases:

>100_bases
CTAAAAAAGGGGGAGAAAGCATGGCGACAATTCGGATCCATGATGAACAAAACACGAGCATTGAAAACCAGGAAGAAGTA
GAACAATTTCTAAAGCGGCA

Product: YkrY

Products: NA

Alternate protein names: Methylthioribulose-1-phosphate dehydratase; MTRu-1-P dehydratase; 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase; HK-MTPenyl-1-P phosphatase

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MRKPLIICDFDGTITTNDNIISIMKQFAPEEWTALKDGVLSKDISIRDGVGRMFNLLPASLKEDITAYVLKQAETRPGFK
EFVSFLDEKGLPFYVVSGGMDFFVYPLLEGIVGKDRIYCNEAAFTSRNIEIRWPYPCDGGCGNDCGCCKPSIIRRLKGRD
DFVVMIGDSVTDVEAAKCSDLCIARDYLLRECEELGLKHAAFGDFRDVRRILEETAEVKEWMSEQKRQELAEVKKELAER
DWFPATSGNLSIKVSEDPLRFLITASGKDKRKETEEDFLLADEEGRPAETGHALKPSAETLLHTYVYQHTNAGCCLHVHT
VDNNVISELYAKEKQVTFRGQEIIKALGLWEEHAEVTVPIIENSAHIPDLAADFAGHLSGDSGAVLIRSHGITVWGKTAF
EAKRMLEAYEFLFSWHLKLKALQAYHV

Sequences:

>Translated_427_residues
MRKPLIICDFDGTITTNDNIISIMKQFAPEEWTALKDGVLSKDISIRDGVGRMFNLLPASLKEDITAYVLKQAETRPGFK
EFVSFLDEKGLPFYVVSGGMDFFVYPLLEGIVGKDRIYCNEAAFTSRNIEIRWPYPCDGGCGNDCGCCKPSIIRRLKGRD
DFVVMIGDSVTDVEAAKCSDLCIARDYLLRECEELGLKHAAFGDFRDVRRILEETAEVKEWMSEQKRQELAEVKKELAER
DWFPATSGNLSIKVSEDPLRFLITASGKDKRKETEEDFLLADEEGRPAETGHALKPSAETLLHTYVYQHTNAGCCLHVHT
VDNNVISELYAKEKQVTFRGQEIIKALGLWEEHAEVTVPIIENSAHIPDLAADFAGHLSGDSGAVLIRSHGITVWGKTAF
EAKRMLEAYEFLFSWHLKLKALQAYHV
>Mature_427_residues
MRKPLIICDFDGTITTNDNIISIMKQFAPEEWTALKDGVLSKDISIRDGVGRMFNLLPASLKEDITAYVLKQAETRPGFK
EFVSFLDEKGLPFYVVSGGMDFFVYPLLEGIVGKDRIYCNEAAFTSRNIEIRWPYPCDGGCGNDCGCCKPSIIRRLKGRD
DFVVMIGDSVTDVEAAKCSDLCIARDYLLRECEELGLKHAAFGDFRDVRRILEETAEVKEWMSEQKRQELAEVKKELAER
DWFPATSGNLSIKVSEDPLRFLITASGKDKRKETEEDFLLADEEGRPAETGHALKPSAETLLHTYVYQHTNAGCCLHVHT
VDNNVISELYAKEKQVTFRGQEIIKALGLWEEHAEVTVPIIENSAHIPDLAADFAGHLSGDSGAVLIRSHGITVWGKTAF
EAKRMLEAYEFLFSWHLKLKALQAYHV

Specific function: Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldolase class II family. MtnB subfamily

Homologues:

Organism=Homo sapiens, GI166235186, Length=210, Percent_Identity=29.5238095238095, Blast_Score=83, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6322484, Length=202, Percent_Identity=31.1881188118812, Blast_Score=77, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6324318, Length=243, Percent_Identity=28.3950617283951, Blast_Score=63, Evalue=7e-11,
Organism=Drosophila melanogaster, GI18859685, Length=216, Percent_Identity=31.0185185185185, Blast_Score=88, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTNBX_BACLD (Q65KJ7)

Other databases:

- EMBL:   CP000002
- EMBL:   AE017333
- RefSeq:   YP_078701.1
- RefSeq:   YP_091110.1
- HSSP:   O31667
- ProteinModelPortal:   Q65KJ7
- SMR:   Q65KJ7
- STRING:   Q65KJ7
- EnsemblBacteria:   EBBACT00000054672
- EnsemblBacteria:   EBBACT00000060121
- GeneID:   3030597
- GeneID:   3101005
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi01516
- KEGG:   bli:BL03541
- NMPDR:   fig|279010.5.peg.1068
- eggNOG:   COG4359
- GeneTree:   EBGT00050000002065
- ProtClustDB:   CLSK747070
- BioCyc:   BLIC279010-1:BLI01516-MONOMER
- BioCyc:   BLIC279010:BL03541-MONOMER
- HAMAP:   MF_01677
- HAMAP:   MF_01680
- InterPro:   IPR001303
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR017718
- InterPro:   IPR006383
- InterPro:   IPR017714
- InterPro:   IPR006384
- Gene3D:   G3DSA:3.40.225.10
- Gene3D:   G3DSA:3.40.50.1000
- TIGRFAMs:   TIGR01489
- TIGRFAMs:   TIGR01488
- TIGRFAMs:   TIGR03328
- TIGRFAMs:   TIGR03333

Pfam domain/function: PF00596 Aldolase_II; PF00702 Hydrolase; SSF53639 Aldolase_II_N; SSF56784 SSF56784

EC number: =4.2.1.109

Molecular weight: Translated: 48068; Mature: 48068

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKPLIICDFDGTITTNDNIISIMKQFAPEEWTALKDGVLSKDISIRDGVGRMFNLLPAS
CCCCEEEEECCCEEECCCHHHHHHHHHCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
LKEDITAYVLKQAETRPGFKEFVSFLDEKGLPFYVVSGGMDFFVYPLLEGIVGKDRIYCN
HHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHCCCCEEEEC
EAAFTSRNIEIRWPYPCDGGCGNDCGCCKPSIIRRLKGRDDFVVMIGDSVTDVEAAKCSD
CHHCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEECCCCCCCHHHHHHH
LCIARDYLLRECEELGLKHAAFGDFRDVRRILEETAEVKEWMSEQKRQELAEVKKELAER
HHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DWFPATSGNLSIKVSEDPLRFLITASGKDKRKETEEDFLLADEEGRPAETGHALKPSAET
CCCCCCCCCEEEEECCCCEEEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHH
LLHTYVYQHTNAGCCLHVHTVDNNVISELYAKEKQVTFRGQEIIKALGLWEEHAEVTVPI
HHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHEECHHHHHHHHCCCCCCCCEEEEE
IENSAHIPDLAADFAGHLSGDSGAVLIRSHGITVWGKTAFEAKRMLEAYEFLFSWHLKLK
ECCCCCCCHHHHHHHHCCCCCCCEEEEEECCEEEECCHHHHHHHHHHHHHHHHHHHHHHH
ALQAYHV
HHHHHCC
>Mature Secondary Structure
MRKPLIICDFDGTITTNDNIISIMKQFAPEEWTALKDGVLSKDISIRDGVGRMFNLLPAS
CCCCEEEEECCCEEECCCHHHHHHHHHCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
LKEDITAYVLKQAETRPGFKEFVSFLDEKGLPFYVVSGGMDFFVYPLLEGIVGKDRIYCN
HHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHCCCCEEEEC
EAAFTSRNIEIRWPYPCDGGCGNDCGCCKPSIIRRLKGRDDFVVMIGDSVTDVEAAKCSD
CHHCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEECCCCCCCHHHHHHH
LCIARDYLLRECEELGLKHAAFGDFRDVRRILEETAEVKEWMSEQKRQELAEVKKELAER
HHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DWFPATSGNLSIKVSEDPLRFLITASGKDKRKETEEDFLLADEEGRPAETGHALKPSAET
CCCCCCCCCEEEEECCCCEEEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHH
LLHTYVYQHTNAGCCLHVHTVDNNVISELYAKEKQVTFRGQEIIKALGLWEEHAEVTVPI
HHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHEECHHHHHHHHCCCCCCCCEEEEE
IENSAHIPDLAADFAGHLSGDSGAVLIRSHGITVWGKTAFEAKRMLEAYEFLFSWHLKLK
ECCCCCCCHHHHHHHHCCCCCCCEEEEEECCEEEECCHHHHHHHHHHHHHHHHHHHHHHH
ALQAYHV
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA