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The map label for this gene is pbpC [H]

Identifier: 52785270

GI number: 52785270

Start: 1478252

End: 1480252

Strand: Direct

Name: pbpC [H]

Synonym: BLi01505

Alternate gene names: 52785270

Gene position: 1478252-1480252 (Clockwise)

Preceding gene: 52785269

Following gene: 52785271

Centisome position: 35.01

GC content: 46.03

Gene sequence:

>2001_bases
ATGAAAAAGAGAGTCATCCATTTGTTTATAGCCGCCGGATTTCTATTGCTCGCCGGAGCCTGTTCTAACGAGCCGACAGC
AAAAGAAAGCATGGACCAATATGTAGACAAATGGAACGAGCAAAAATTTGAAGAAATGTATGAACAGCTGTCGGCTGAAG
CGCAAAAATCGATTTCAAAAGACGATTTCATCAAGCGTAATCAATCTATTTATGAACAGATTGGAGTTTCCGATTTGAAG
GTTTCAACCGTCGACAACGATGAAGATGAAAAAAATAAAGAGAAAAATGATTCGGTGACGATACCGTATAAAGTCAGCAT
GAAGACATTGGCCGGTCCGGTTTCTTTTCAAGGCAAGGCAAAGCTTGTCAAAGAAAAAAAAGACGGAGACACTTCATGGA
AGGTCAACTGGAACCAATCCTTTATTTTTTCACAGCTGAAGAAAGGGGAGACCATCCGGATTACCGCCAAGGAGCCAACT
AGAGGCATCATTTATGACAGAAACGGAAAGGCGCTCGCTACGAATGCGACAGTGCCTGAAATCGGCGTCGTTCCGGGGCA
GCTCGGAGATGATAAAGACGGTGTCATCAAAAAGCTCGCGAACATGCTTGATATGGAAAAAGAAGACATAGAAAAACAGC
TGTCCGCAAGCTGGGTGACGGACGATTCATTCGTTCCCCTGAAAAAAGTGAAGCCTGGCAGCACCGAGCTTCTCAAAAAA
GCGACCTCTCTCCCCGGGGTTTTGAAGCAGGATACGCAGTCAAGATACTATCCTTACGGTGAAAAAGCCGCACATCTTAC
CGGTTACATACGGCCGATTACCGAAGAGGAATTAAAACAGAATAAAGAAGGCTACAGCGAGCATTCACTGCTCGGAATCG
TCGGTCTCGAACATATTTATGAAAAAGAGCTCAGAGGAGAAATCGGCTGGACGATTTCGATCCCTGAATCAGGCGCGACG
GTTGCGTCAAAGGATGCAAAAGACGGAAAAGACATCCACACCACGATCGACATTAAGAAACAGGAAGAACTGTACAGCCA
GTTAAAAGATGACTCCGGCGCTGCCGTTGCTTTAGAACCGCAGACTGGAGAAACGCTGGCGCTTGTCAGCGCGCCTTCAT
ATGATCCGAACGGGTTTTTGTTCGGCTGGAAAAAAGGAGAATGGGAAAAGCTCAACAAAGATGCGTCTGCGCCATTCACC
TCTAAATTTAATAAAACTTATGCTCCGGGTTCAACGATCAAACCGATCACCGCTTCAATCGGTCTGAAAAATGATGCGAT
CAAAGCGGATGAACCTAAGAAGATCGAAGGGAAGGAATGGCAGAAAGATTCGTCATGGGGCGGATATAAAGTCACACGGG
TTTCCGATCGACTAAGCGACGTCAACTTGGAAAACGCGCTGATCACATCCGACAACATTTATTTCGCCCAGACTGCCCTT
GATACAGGCAAGGATCAATTTGTCGAAGGCCTGAAATCATTCGGCTTTGAGGAAAAGCTTGATTATGAATTCCCGACGAA
GTCTTCCTCCATATCAAACGAAGGAATCGACTCGGATATTCTCCTTGCCGATTCAGGATACGGACAGGGGCAAATGCTGA
TGTCGCCGATACACCTTGCGGCAAGCTATACGCCTTTCTTGAATGACGGTAATCTGATCAAGCCGCACCTGATCAAAAAG
GACGGCGAAGAGAAAGAAATATGGCATAAAAACGTACTGCCCACAGGCGGAGCAGAAGCGATTACAAAAGGGTTAAAAGG
CGTTGTAGAAGACCCGCGCGGCTCGGCTTACAAGCCGGTTGTCAAAGGGCTTACGATCGCAGGGAAAACGGGAACGGCCG
AACTGAAAACGAAAAAAGACGAAAAAGGCAAAGAAAACGGCTGGTTCACCGCCTATGATTACAAAAACAAAAACCTTTTA
ATCACGATGATGATCGAGGATGTTTCAGACCGCGGCGGCAGCTCATACGTCGTTAATAAAGTGAAAAAAGTGTTTAAATA
A

Upstream 100 bases:

>100_bases
AGTCAAACTGTCTTTTTTTATGATCATAAAGTCGGTCGCTGTATTTATTTGTATGATATAATGCTTAAATGGCGGACTTG
AAAAAAAGGGGGAAACAACG

Downstream 100 bases:

>100_bases
GCACCCTTCAGGGTGCTTATTTTTTTGCCGAAAACTGGATGTGTGGAATGTGCCGAAACGGAAAGGATATGGATGAAACG
ACTAAAGAAAGGAATGTCAT

Product: PbpC

Products: NA

Alternate protein names: PBP 3; PSPB20; Penicillin-binding protein C [H]

Number of amino acids: Translated: 666; Mature: 666

Protein sequence:

>666_residues
MKKRVIHLFIAAGFLLLAGACSNEPTAKESMDQYVDKWNEQKFEEMYEQLSAEAQKSISKDDFIKRNQSIYEQIGVSDLK
VSTVDNDEDEKNKEKNDSVTIPYKVSMKTLAGPVSFQGKAKLVKEKKDGDTSWKVNWNQSFIFSQLKKGETIRITAKEPT
RGIIYDRNGKALATNATVPEIGVVPGQLGDDKDGVIKKLANMLDMEKEDIEKQLSASWVTDDSFVPLKKVKPGSTELLKK
ATSLPGVLKQDTQSRYYPYGEKAAHLTGYIRPITEEELKQNKEGYSEHSLLGIVGLEHIYEKELRGEIGWTISIPESGAT
VASKDAKDGKDIHTTIDIKKQEELYSQLKDDSGAAVALEPQTGETLALVSAPSYDPNGFLFGWKKGEWEKLNKDASAPFT
SKFNKTYAPGSTIKPITASIGLKNDAIKADEPKKIEGKEWQKDSSWGGYKVTRVSDRLSDVNLENALITSDNIYFAQTAL
DTGKDQFVEGLKSFGFEEKLDYEFPTKSSSISNEGIDSDILLADSGYGQGQMLMSPIHLAASYTPFLNDGNLIKPHLIKK
DGEEKEIWHKNVLPTGGAEAITKGLKGVVEDPRGSAYKPVVKGLTIAGKTGTAELKTKKDEKGKENGWFTAYDYKNKNLL
ITMMIEDVSDRGGSSYVVNKVKKVFK

Sequences:

>Translated_666_residues
MKKRVIHLFIAAGFLLLAGACSNEPTAKESMDQYVDKWNEQKFEEMYEQLSAEAQKSISKDDFIKRNQSIYEQIGVSDLK
VSTVDNDEDEKNKEKNDSVTIPYKVSMKTLAGPVSFQGKAKLVKEKKDGDTSWKVNWNQSFIFSQLKKGETIRITAKEPT
RGIIYDRNGKALATNATVPEIGVVPGQLGDDKDGVIKKLANMLDMEKEDIEKQLSASWVTDDSFVPLKKVKPGSTELLKK
ATSLPGVLKQDTQSRYYPYGEKAAHLTGYIRPITEEELKQNKEGYSEHSLLGIVGLEHIYEKELRGEIGWTISIPESGAT
VASKDAKDGKDIHTTIDIKKQEELYSQLKDDSGAAVALEPQTGETLALVSAPSYDPNGFLFGWKKGEWEKLNKDASAPFT
SKFNKTYAPGSTIKPITASIGLKNDAIKADEPKKIEGKEWQKDSSWGGYKVTRVSDRLSDVNLENALITSDNIYFAQTAL
DTGKDQFVEGLKSFGFEEKLDYEFPTKSSSISNEGIDSDILLADSGYGQGQMLMSPIHLAASYTPFLNDGNLIKPHLIKK
DGEEKEIWHKNVLPTGGAEAITKGLKGVVEDPRGSAYKPVVKGLTIAGKTGTAELKTKKDEKGKENGWFTAYDYKNKNLL
ITMMIEDVSDRGGSSYVVNKVKKVFK
>Mature_666_residues
MKKRVIHLFIAAGFLLLAGACSNEPTAKESMDQYVDKWNEQKFEEMYEQLSAEAQKSISKDDFIKRNQSIYEQIGVSDLK
VSTVDNDEDEKNKEKNDSVTIPYKVSMKTLAGPVSFQGKAKLVKEKKDGDTSWKVNWNQSFIFSQLKKGETIRITAKEPT
RGIIYDRNGKALATNATVPEIGVVPGQLGDDKDGVIKKLANMLDMEKEDIEKQLSASWVTDDSFVPLKKVKPGSTELLKK
ATSLPGVLKQDTQSRYYPYGEKAAHLTGYIRPITEEELKQNKEGYSEHSLLGIVGLEHIYEKELRGEIGWTISIPESGAT
VASKDAKDGKDIHTTIDIKKQEELYSQLKDDSGAAVALEPQTGETLALVSAPSYDPNGFLFGWKKGEWEKLNKDASAPFT
SKFNKTYAPGSTIKPITASIGLKNDAIKADEPKKIEGKEWQKDSSWGGYKVTRVSDRLSDVNLENALITSDNIYFAQTAL
DTGKDQFVEGLKSFGFEEKLDYEFPTKSSSISNEGIDSDILLADSGYGQGQMLMSPIHLAASYTPFLNDGNLIKPHLIKK
DGEEKEIWHKNVLPTGGAEAITKGLKGVVEDPRGSAYKPVVKGLTIAGKTGTAELKTKKDEKGKENGWFTAYDYKNKNLL
ITMMIEDVSDRGGSSYVVNKVKKVFK

Specific function: Cell Wall Formation; Pbp-2 Is Responsible For The Determination Of The Rod Shape Of The Cell. Its Synthesize Cross- Linked Peptidoglycan From The Lipid Intermediates. [C]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786854, Length=553, Percent_Identity=27.4864376130199, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI1786272, Length=514, Percent_Identity=26.4591439688716, Blast_Score=124, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR007887
- InterPro:   IPR005311
- InterPro:   IPR001460 [H]

Pfam domain/function: PF05223 MecA_N; PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 73792; Mature: 73792

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKRVIHLFIAAGFLLLAGACSNEPTAKESMDQYVDKWNEQKFEEMYEQLSAEAQKSISK
CCCCEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
DDFIKRNQSIYEQIGVSDLKVSTVDNDEDEKNKEKNDSVTIPYKVSMKTLAGPVSFQGKA
HHHHHHHHHHHHHCCCCCEEEEECCCCCHHHCCCCCCCEEEEEEEEHHHHCCCCCCCCCH
KLVKEKKDGDTSWKVNWNQSFIFSQLKKGETIRITAKEPTRGIIYDRNGKALATNATVPE
HHHHHCCCCCCEEEEECCHHHHHHHHCCCCEEEEEECCCCCCEEEECCCCEEEECCCCCC
IGVVPGQLGDDKDGVIKKLANMLDMEKEDIEKQLSASWVTDDSFVPLKKVKPGSTELLKK
CCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCHHCCCCCHHHHHHH
ATSLPGVLKQDTQSRYYPYGEKAAHLTGYIRPITEEELKQNKEGYSEHSLLGIVGLEHIY
HHCCCCHHHHCCCCCCCCCCCCHHHHHHEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHH
EKELRGEIGWTISIPESGATVASKDAKDGKDIHTTIDIKKQEELYSQLKDDSGAAVALEP
HHHHCCCCCEEEECCCCCCEECCCCCCCCCCEEEEEECCHHHHHHHHHCCCCCCEEEECC
QTGETLALVSAPSYDPNGFLFGWKKGEWEKLNKDASAPFTSKFNKTYAPGSTIKPITASI
CCCCEEEEEECCCCCCCCEEEECCCCCHHHHCCCCCCCCHHHCCCCCCCCCCCCCEEEEC
GLKNDAIKADEPKKIEGKEWQKDSSWGGYKVTRVSDRLSDVNLENALITSDNIYFAQTAL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHCCCCCCEEEECCCEEEEEEHH
DTGKDQFVEGLKSFGFEEKLDYEFPTKSSSISNEGIDSDILLADSGYGQGQMLMSPIHLA
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHH
ASYTPFLNDGNLIKPHLIKKDGEEKEIWHKNVLPTGGAEAITKGLKGVVEDPRGSAYKPV
HCCCCCCCCCCEECCHHCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCHH
VKGLTIAGKTGTAELKTKKDEKGKENGWFTAYDYKNKNLLITMMIEDVSDRGGSSYVVNK
HCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEEECCCCCCCCHHHHHH
VKKVFK
HHHHHC
>Mature Secondary Structure
MKKRVIHLFIAAGFLLLAGACSNEPTAKESMDQYVDKWNEQKFEEMYEQLSAEAQKSISK
CCCCEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
DDFIKRNQSIYEQIGVSDLKVSTVDNDEDEKNKEKNDSVTIPYKVSMKTLAGPVSFQGKA
HHHHHHHHHHHHHCCCCCEEEEECCCCCHHHCCCCCCCEEEEEEEEHHHHCCCCCCCCCH
KLVKEKKDGDTSWKVNWNQSFIFSQLKKGETIRITAKEPTRGIIYDRNGKALATNATVPE
HHHHHCCCCCCEEEEECCHHHHHHHHCCCCEEEEEECCCCCCEEEECCCCEEEECCCCCC
IGVVPGQLGDDKDGVIKKLANMLDMEKEDIEKQLSASWVTDDSFVPLKKVKPGSTELLKK
CCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCHHCCCCCHHHHHHH
ATSLPGVLKQDTQSRYYPYGEKAAHLTGYIRPITEEELKQNKEGYSEHSLLGIVGLEHIY
HHCCCCHHHHCCCCCCCCCCCCHHHHHHEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHH
EKELRGEIGWTISIPESGATVASKDAKDGKDIHTTIDIKKQEELYSQLKDDSGAAVALEP
HHHHCCCCCEEEECCCCCCEECCCCCCCCCCEEEEEECCHHHHHHHHHCCCCCCEEEECC
QTGETLALVSAPSYDPNGFLFGWKKGEWEKLNKDASAPFTSKFNKTYAPGSTIKPITASI
CCCCEEEEEECCCCCCCCEEEECCCCCHHHHCCCCCCCCHHHCCCCCCCCCCCCCEEEEC
GLKNDAIKADEPKKIEGKEWQKDSSWGGYKVTRVSDRLSDVNLENALITSDNIYFAQTAL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHCCCCCCEEEECCCEEEEEEHH
DTGKDQFVEGLKSFGFEEKLDYEFPTKSSSISNEGIDSDILLADSGYGQGQMLMSPIHLA
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHH
ASYTPFLNDGNLIKPHLIKKDGEEKEIWHKNVLPTGGAEAITKGLKGVVEDPRGSAYKPV
HCCCCCCCCCCEECCHHCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCHH
VKGLTIAGKTGTAELKTKKDEKGKENGWFTAYDYKNKNLLITMMIEDVSDRGGSSYVVNK
HCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEEECCCCCCCCHHHHHH
VKKVFK
HHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 3145906 [H]