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The map label for this gene is ykrL

Identifier: 52785268

GI number: 52785268

Start: 1475750

End: 1476643

Strand: Direct

Name: ykrL

Synonym: BLi01503

Alternate gene names: 52785268

Gene position: 1475750-1476643 (Clockwise)

Preceding gene: 52785265

Following gene: 52785269

Centisome position: 34.95

GC content: 49.55

Gene sequence:

>894_bases
ATGGGAAAAAGAATCTTTCTCTTTCTTTTATCGAACATCTTAGTCATTACGACGATCGGTATCGTGCTTTCGATTATCGG
TTCGCTGACAGGGGTAGGCACGTATTTCACGGCTAACGGCGGCATCGATATTGTTGCGCTTCTCGTATTTAGTGCAGTTG
TCGGTTTTGTCGGCTCCTTTATGTCGCTCTTGATGTCAAGATGGATGGCGAAAATGGCGATGGGCGTTCAGGTGCTGAAT
CCTGATAAGCAAACGCTCAGCTATGAAGAACAGCAGCTCGTTGACCGGGTATATAAGCTGTCCCGCGCTGCCGGACTGAC
AAAGATGCCTGAAGTCGGCATCTACAATTCACGCGAAGTGAATGCCTTTGCGACCGGGCCGTCTAAAAACCGCTCGCTTG
TCGCTGTATCGACGGGCCTTCTTCAGGAAATGGATGACGACGCAGTGGAAGGCGTACTTGCCCACGAAGTGGCGCATATT
GCAAACGGCGATATGGTGACGATGACGCTCCTTCAAGGAATCGTCAATACGTTCGTTGTTTTCTTCGCAAGGATTGCGGC
ATGGGCTGTTTCACGCGTTGTCCGTGAAGAGCTGGCGCCGATCGTTCACTTTATCGCGGTCATCGTATTCCAAATTGTGT
TCTCTATTCTCGGAAGCCTTGTCGTGTTTGCGTACTCCCGCCACCGCGAATATCATGCGGATAGAGGAGGAGCAGACCTT
GCAGGCAAGGATAAGATGATTCACGCGCTCCGCTCGCTTGAGCAGTACACTTCAAGAGTCAAAGAAGAACAGGCATCTGT
TGCAACTTTAAAAATCAACGGGAAAAAGCATACATCGCTTTTCTCAACACACCCTGATTTAAGCGACAGAATCCGCCGTC
TGGAAGCAAAATAA

Upstream 100 bases:

>100_bases
ATAAACATTATCTTACGTCTTATCACTTGCATTTTCAATTCTATGCCGTATAATTTTATTATACGAGTTCATTTGATCTT
ATTATAACATGGAGGTAATC

Downstream 100 bases:

>100_bases
TAAAGATGCAAACCCCCTTTTTCAAGGGGGTTTGCTTTTTAAATTTAAAAATCGAAAAGCGGCTGTACATAATAGCATGT
TTCCTTTAAAATGGAACACG

Product: heat shock protein HtpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MGKRIFLFLLSNILVITTIGIVLSIIGSLTGVGTYFTANGGIDIVALLVFSAVVGFVGSFMSLLMSRWMAKMAMGVQVLN
PDKQTLSYEEQQLVDRVYKLSRAAGLTKMPEVGIYNSREVNAFATGPSKNRSLVAVSTGLLQEMDDDAVEGVLAHEVAHI
ANGDMVTMTLLQGIVNTFVVFFARIAAWAVSRVVREELAPIVHFIAVIVFQIVFSILGSLVVFAYSRHREYHADRGGADL
AGKDKMIHALRSLEQYTSRVKEEQASVATLKINGKKHTSLFSTHPDLSDRIRRLEAK

Sequences:

>Translated_297_residues
MGKRIFLFLLSNILVITTIGIVLSIIGSLTGVGTYFTANGGIDIVALLVFSAVVGFVGSFMSLLMSRWMAKMAMGVQVLN
PDKQTLSYEEQQLVDRVYKLSRAAGLTKMPEVGIYNSREVNAFATGPSKNRSLVAVSTGLLQEMDDDAVEGVLAHEVAHI
ANGDMVTMTLLQGIVNTFVVFFARIAAWAVSRVVREELAPIVHFIAVIVFQIVFSILGSLVVFAYSRHREYHADRGGADL
AGKDKMIHALRSLEQYTSRVKEEQASVATLKINGKKHTSLFSTHPDLSDRIRRLEAK
>Mature_296_residues
GKRIFLFLLSNILVITTIGIVLSIIGSLTGVGTYFTANGGIDIVALLVFSAVVGFVGSFMSLLMSRWMAKMAMGVQVLNP
DKQTLSYEEQQLVDRVYKLSRAAGLTKMPEVGIYNSREVNAFATGPSKNRSLVAVSTGLLQEMDDDAVEGVLAHEVAHIA
NGDMVTMTLLQGIVNTFVVFFARIAAWAVSRVVREELAPIVHFIAVIVFQIVFSILGSLVVFAYSRHREYHADRGGADLA
GKDKMIHALRSLEQYTSRVKEEQASVATLKINGKKHTSLFSTHPDLSDRIRRLEAK

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family

Homologues:

Organism=Escherichia coli, GI1788133, Length=301, Percent_Identity=46.843853820598, Blast_Score=236, Evalue=1e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HTPX_BACLD (Q65KL0)

Other databases:

- EMBL:   CP000002
- EMBL:   AE017333
- RefSeq:   YP_078687.1
- RefSeq:   YP_091097.1
- ProteinModelPortal:   Q65KL0
- SMR:   Q65KL0
- STRING:   Q65KL0
- MEROPS:   M48.002
- EnsemblBacteria:   EBBACT00000056797
- EnsemblBacteria:   EBBACT00000060240
- GeneID:   3030578
- GeneID:   3098739
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi01503
- KEGG:   bli:BL03531
- NMPDR:   fig|279010.5.peg.1055
- eggNOG:   COG0501
- GeneTree:   EBGT00050000002110
- HOGENOM:   HBG739460
- OMA:   NRFLTAN
- ProtClustDB:   PRK05457
- BioCyc:   BLIC279010-1:BLI01503-MONOMER
- BioCyc:   BLIC279010:BL03531-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_00188
- InterPro:   IPR022919
- InterPro:   IPR001915

Pfam domain/function: PF01435 Peptidase_M48

EC number: 3.4.24.-

Molecular weight: Translated: 32578; Mature: 32446

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: ACT_SITE 156-156

Signals:

None

Transmembrane regions:

HASH(0xf0f8bd4)-; HASH(0xf3d57bc)-; HASH(0xca124c8)-; HASH(0xdcdf764)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKRIFLFLLSNILVITTIGIVLSIIGSLTGVGTYFTANGGIDIVALLVFSAVVGFVGSF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHH
MSLLMSRWMAKMAMGVQVLNPDKQTLSYEEQQLVDRVYKLSRAAGLTKMPEVGIYNSREV
HHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
NAFATGPSKNRSLVAVSTGLLQEMDDDAVEGVLAHEVAHIANGDMVTMTLLQGIVNTFVV
CEEECCCCCCCEEEEEHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
FFARIAAWAVSRVVREELAPIVHFIAVIVFQIVFSILGSLVVFAYSRHREYHADRGGADL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
AGKDKMIHALRSLEQYTSRVKEEQASVATLKINGKKHTSLFSTHPDLSDRIRRLEAK
CCHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCHHCCHHCCCCCHHHHHHHHCCH
>Mature Secondary Structure 
GKRIFLFLLSNILVITTIGIVLSIIGSLTGVGTYFTANGGIDIVALLVFSAVVGFVGSF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHH
MSLLMSRWMAKMAMGVQVLNPDKQTLSYEEQQLVDRVYKLSRAAGLTKMPEVGIYNSREV
HHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
NAFATGPSKNRSLVAVSTGLLQEMDDDAVEGVLAHEVAHIANGDMVTMTLLQGIVNTFVV
CEEECCCCCCCEEEEEHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
FFARIAAWAVSRVVREELAPIVHFIAVIVFQIVFSILGSLVVFAYSRHREYHADRGGADL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
AGKDKMIHALRSLEQYTSRVKEEQASVATLKINGKKHTSLFSTHPDLSDRIRRLEAK
CCHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCHHCCHHCCCCCHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA