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The map label for this gene is yesM [H]

Identifier: 52785134

GI number: 52785134

Start: 1357210

End: 1358946

Strand: Direct

Name: yesM [H]

Synonym: BLi01366

Alternate gene names: 52785134

Gene position: 1357210-1358946 (Clockwise)

Preceding gene: 52785133

Following gene: 52785135

Centisome position: 32.14

GC content: 47.09

Gene sequence:

>1737_bases
GTGAACCGGTATCAGCATTTAAAAATTAAAGATCAATTGTTTATTTTGATTTCACTGATCATGGCCGTTTCGCTCATCCT
GATCTTGAGCGGCATTCAATACGCGTTCCGGGTATATGACCAGCAGATTTACAGGAAGTCGTCACAGGTGCTGATGCTAT
CATCAAAAAGCATTGAAGATGAATTGAAAAAGATTGAGGATGTGTCATATCAAATCACCACTGACGCAGACATCCAAGCG
AACCTCCTGAAAGCCGGCCGCGGCCAGAACAAATACGGACGCTACCGGATAAAAAGCAAAATTTGGGATAAGCTGGCCGA
ATATACCGGCTCTAAGCGGTACATTAAATCGATTCATTTGTTTGATGCTTCCGGCACCGAGTACTCCGCAGGGGCGAATT
TAACCGAAGCATTGCGGGAGCAAAAGAATGCACTGATCGAAAAAGCGTCGCGCCAAAAAGGCAGCAACATGTGGGAGCCC
ATGCCGGGTGAAACCGGCGAGCTGTTATCCGTCCGGGAAATCCGCTCCTATGAGCGTTTAAACCTTGACCACCTGGGAAC
AGTGGTGATTGTCGCCGATTTAAAACGGGTGATCGGCGATCTTCCGAAAGACTGGGGGGAAGGCGCGGGCAAGATTGCGA
TGTCGGACGGGCGGGAGCTGTTTTTTTCTGAAATGCCTTTCAGCCAAACCGATGGCCTCCGATTGTCTTCTCATGCTGAA
AACGGATATGACATTGTGGAGGAAAACGGCCAGCGGTTTTTCGTTTCATATGTCAAATCAGCGTATAAGAATTGGACATA
TTGGAGCCTGATCCCCTTTGACGCTATGTTTTCGAAAATTTCTGCGATGAAGACGATCCTGATTTCCCTTTTTATCCTTT
TTTTTCTGATTGCGGTTCTCTTTGGAAGAAAAATGGCCAGGGGCATTACGAGCCCGATTGAGAAGCTGGTGGCGGCCATG
AAAAATGTCCAAAACGGCGATTTTAAACTGGCGCCGCTCACTCGCGCTCCTTTAGACCGGCAGGATGAAGTCAGCGTCTT
AAACCGCAATTTCTTTACAATGGTTGAACGGATCAATGAACTGATTGCCGAGAACTACAAGAAGCAGCTGATGCTGAAAG
AGACGGAATTCAAAGCGCTTCAAGCGCAAATCAACCCCCACTTTTTATACAACACGCTCGAGTCGATCAACTGGCTTGCA
AAAACGAACCGGCAGCCGCAAATTTCAAAGATGACGGAATCTCTAGGGTTTTTGCTCAGAAATGCCATCAATATGAAAAC
CGACGTGCTGACGATCGAGGAAGAAGCTGAAATCGTGCGCCACTATTTTACGATTCAGCGGTTTCGCTTTGAGGAGCGGC
TCGTTTTTGAGCTCGACATTGAGCCGGCTGTGAAAAAATGCCGCGTACCTAAGCTTGTTCTCCAGCCTTTGGCTGAAAAC
GCGATTACATATTGCCTTGAGCCCTTCATTGAACCTTGCCATATTCAAATCAAAGCATATAAAAAAGAAGAGCTTGTCTA
TTTAACGGTTGCCGACAACGGCCCCGGCATGGATGAAGACTTTTTGGAAAAGGCGAGAAAGGAGCTTGTCCGGACAACCG
GGAGAGGAATCGGGCTGCAAAATATCGACGAGCGCATTCAGCTGATGTTTGGCAAAGGGTATGGCTTGACGATTTCAAGC
GAAAAGAATAAGGGAACCGTGATGATGATTAAAATACCATTTCAAAGCGGGGTGTGA

Upstream 100 bases:

>100_bases
ATTTTGACGAAGCTTTCGTTTCAGGCATTCCGTGCAATCGACGGGCGCCGGACAGACAAGCAGGCTGCCGCCCCACGCTT
GAAATGAAGGTGTTCGTTCG

Downstream 100 bases:

>100_bases
TGATGTATAAAGTGCTGTTGGCGGACGATGAACGGATTATTCTTGACGGCATCTCCAGCATGATCGAGTGGAATTCGTTC
GGGACGTCTTTGATCGGGGC

Product: YesM

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 578; Mature: 578

Protein sequence:

>578_residues
MNRYQHLKIKDQLFILISLIMAVSLILILSGIQYAFRVYDQQIYRKSSQVLMLSSKSIEDELKKIEDVSYQITTDADIQA
NLLKAGRGQNKYGRYRIKSKIWDKLAEYTGSKRYIKSIHLFDASGTEYSAGANLTEALREQKNALIEKASRQKGSNMWEP
MPGETGELLSVREIRSYERLNLDHLGTVVIVADLKRVIGDLPKDWGEGAGKIAMSDGRELFFSEMPFSQTDGLRLSSHAE
NGYDIVEENGQRFFVSYVKSAYKNWTYWSLIPFDAMFSKISAMKTILISLFILFFLIAVLFGRKMARGITSPIEKLVAAM
KNVQNGDFKLAPLTRAPLDRQDEVSVLNRNFFTMVERINELIAENYKKQLMLKETEFKALQAQINPHFLYNTLESINWLA
KTNRQPQISKMTESLGFLLRNAINMKTDVLTIEEEAEIVRHYFTIQRFRFEERLVFELDIEPAVKKCRVPKLVLQPLAEN
AITYCLEPFIEPCHIQIKAYKKEELVYLTVADNGPGMDEDFLEKARKELVRTTGRGIGLQNIDERIQLMFGKGYGLTISS
EKNKGTVMMIKIPFQSGV

Sequences:

>Translated_578_residues
MNRYQHLKIKDQLFILISLIMAVSLILILSGIQYAFRVYDQQIYRKSSQVLMLSSKSIEDELKKIEDVSYQITTDADIQA
NLLKAGRGQNKYGRYRIKSKIWDKLAEYTGSKRYIKSIHLFDASGTEYSAGANLTEALREQKNALIEKASRQKGSNMWEP
MPGETGELLSVREIRSYERLNLDHLGTVVIVADLKRVIGDLPKDWGEGAGKIAMSDGRELFFSEMPFSQTDGLRLSSHAE
NGYDIVEENGQRFFVSYVKSAYKNWTYWSLIPFDAMFSKISAMKTILISLFILFFLIAVLFGRKMARGITSPIEKLVAAM
KNVQNGDFKLAPLTRAPLDRQDEVSVLNRNFFTMVERINELIAENYKKQLMLKETEFKALQAQINPHFLYNTLESINWLA
KTNRQPQISKMTESLGFLLRNAINMKTDVLTIEEEAEIVRHYFTIQRFRFEERLVFELDIEPAVKKCRVPKLVLQPLAEN
AITYCLEPFIEPCHIQIKAYKKEELVYLTVADNGPGMDEDFLEKARKELVRTTGRGIGLQNIDERIQLMFGKGYGLTISS
EKNKGTVMMIKIPFQSGV
>Mature_578_residues
MNRYQHLKIKDQLFILISLIMAVSLILILSGIQYAFRVYDQQIYRKSSQVLMLSSKSIEDELKKIEDVSYQITTDADIQA
NLLKAGRGQNKYGRYRIKSKIWDKLAEYTGSKRYIKSIHLFDASGTEYSAGANLTEALREQKNALIEKASRQKGSNMWEP
MPGETGELLSVREIRSYERLNLDHLGTVVIVADLKRVIGDLPKDWGEGAGKIAMSDGRELFFSEMPFSQTDGLRLSSHAE
NGYDIVEENGQRFFVSYVKSAYKNWTYWSLIPFDAMFSKISAMKTILISLFILFFLIAVLFGRKMARGITSPIEKLVAAM
KNVQNGDFKLAPLTRAPLDRQDEVSVLNRNFFTMVERINELIAENYKKQLMLKETEFKALQAQINPHFLYNTLESINWLA
KTNRQPQISKMTESLGFLLRNAINMKTDVLTIEEEAEIVRHYFTIQRFRFEERLVFELDIEPAVKKCRVPKLVLQPLAEN
AITYCLEPFIEPCHIQIKAYKKEELVYLTVADNGPGMDEDFLEKARKELVRTTGRGIGLQNIDERIQLMFGKGYGLTISS
EKNKGTVMMIKIPFQSGV

Specific function: Member of the two-component regulatory system yesM/yesN. Probably activates yesN by phosphorylation [H]

COG id: COG2972

COG function: function code T; Predicted signal transduction protein with a C-terminal ATPase domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788446, Length=217, Percent_Identity=27.1889400921659, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1788723, Length=185, Percent_Identity=33.5135135135135, Blast_Score=99, Evalue=9e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR010559
- InterPro:   IPR005467 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 66337; Mature: 66337

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRYQHLKIKDQLFILISLIMAVSLILILSGIQYAFRVYDQQIYRKSSQVLMLSSKSIED
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHH
ELKKIEDVSYQITTDADIQANLLKAGRGQNKYGRYRIKSKIWDKLAEYTGSKRYIKSIHL
HHHHHHCCCEEEECCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHEEEE
FDASGTEYSAGANLTEALREQKNALIEKASRQKGSNMWEPMPGETGELLSVREIRSYERL
EECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHC
NLDHLGTVVIVADLKRVIGDLPKDWGEGAGKIAMSDGRELFFSEMPFSQTDGLRLSSHAE
CHHHHHHHHHHHHHHHHHHCCCHHHCCCCCEEEECCCCHHHHHCCCCCCCCCCEEECCCC
NGYDIVEENGQRFFVSYVKSAYKNWTYWSLIPFDAMFSKISAMKTILISLFILFFLIAVL
CCCHHHHCCCCCHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGRKMARGITSPIEKLVAAMKNVQNGDFKLAPLTRAPLDRQDEVSVLNRNFFTMVERINE
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHH
LIAENYKKQLMLKETEFKALQAQINPHFLYNTLESINWLAKTNRQPQISKMTESLGFLLR
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
NAINMKTDVLTIEEEAEIVRHYFTIQRFRFEERLVFELDIEPAVKKCRVPKLVLQPLAEN
HHHCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHCCCHHHHHHHHHHH
AITYCLEPFIEPCHIQIKAYKKEELVYLTVADNGPGMDEDFLEKARKELVRTTGRGIGLQ
HHHHHHHHCCCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCC
NIDERIQLMFGKGYGLTISSEKNKGTVMMIKIPFQSGV
CHHHHHHEEECCCCEEEEECCCCCCEEEEEEECCCCCC
>Mature Secondary Structure
MNRYQHLKIKDQLFILISLIMAVSLILILSGIQYAFRVYDQQIYRKSSQVLMLSSKSIED
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHH
ELKKIEDVSYQITTDADIQANLLKAGRGQNKYGRYRIKSKIWDKLAEYTGSKRYIKSIHL
HHHHHHCCCEEEECCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHEEEE
FDASGTEYSAGANLTEALREQKNALIEKASRQKGSNMWEPMPGETGELLSVREIRSYERL
EECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHC
NLDHLGTVVIVADLKRVIGDLPKDWGEGAGKIAMSDGRELFFSEMPFSQTDGLRLSSHAE
CHHHHHHHHHHHHHHHHHHCCCHHHCCCCCEEEECCCCHHHHHCCCCCCCCCCEEECCCC
NGYDIVEENGQRFFVSYVKSAYKNWTYWSLIPFDAMFSKISAMKTILISLFILFFLIAVL
CCCHHHHCCCCCHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGRKMARGITSPIEKLVAAMKNVQNGDFKLAPLTRAPLDRQDEVSVLNRNFFTMVERINE
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHH
LIAENYKKQLMLKETEFKALQAQINPHFLYNTLESINWLAKTNRQPQISKMTESLGFLLR
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
NAINMKTDVLTIEEEAEIVRHYFTIQRFRFEERLVFELDIEPAVKKCRVPKLVLQPLAEN
HHHCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHCCCHHHHHHHHHHH
AITYCLEPFIEPCHIQIKAYKKEELVYLTVADNGPGMDEDFLEKARKELVRTTGRGIGLQ
HHHHHHHHCCCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCC
NIDERIQLMFGKGYGLTISSEKNKGTVMMIKIPFQSGV
CHHHHHHEEECCCCEEEEECCCCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]