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The map label for this gene is goxB [H]

Identifier: 52785032

GI number: 52785032

Start: 1272663

End: 1273772

Strand: Direct

Name: goxB [H]

Synonym: BLi01261

Alternate gene names: 52785032

Gene position: 1272663-1273772 (Clockwise)

Preceding gene: 52785031

Following gene: 52785033

Centisome position: 30.14

GC content: 53.69

Gene sequence:

>1110_bases
ATGAGAAAGCGCTATGATACGATCGTGATCGGCGGAGGCATCATCGGGACTTCCATCGCTTATCATCTTGCGAAAGCGGG
GAAAAAAACGGCCGTGTTTGAAAGCGGGGAAGTCGGCAAAAAAGCGACGAGCGCGGCTGCGGGCATGCTCGGCGCCCATG
CGGAATGCGATAAACCCGGTACCTTTTTCGAATTTGCCAGAGCCAGTCAAAAAGCCTATAAGCGCCTGACGGGGGAATTG
AAAGACATAAGCGGCATTGATATCAGAAGGCATGACGGAGGGATATTAAAGCTGGCATTTTCAGAAAGCGACCGCGAACA
CCTGATGCAAATGGGTGCACTGGATTCTGTGGAATGGCTTGAAGCTGATGAAGTATATAAATTAGAACCGAATGCCGGAA
AAGGAATTCTCGGCGCCAATTTTATCAGGGACGACGTCCATGTCGAACCGGCTGCAGTGTGCAGGGCATTTGCCAGGGGA
GCCCGGATGCTCGGTGCAGATGTCTTCGAGTATACGCCCGTTTTATCGATAGAATCCGAAGCGGGGGCCGTCCGCGTCAC
GTCCGCTTCCGGCACAGCGGAGGCGGAGCACGCTGTCATTGCAAGCGGCGTGTGGAGCGGAGCTTTGTTTAAACAAATCG
GCTTAGACAAAAGGTTTTACCCCGTCAAAGGGGAGTGCCTGTCCGTATGGAATGACGGCATCTCTTTGACGAGAACGCTT
TACCATGATCATTGCTACATCGTTCCGCGCCATAGCGGAAGGCTTGTCGTCGGCGCGACGATGAAGCCCGGGGACTGGAA
TGAGCAGCCGGAACTTGGCGGAATCGAGGAGTTGATCCGAAAAGCCAAGTCGATGCTCCCTGGGATTGAATCCATGAAAA
TCGACCAATGCTGGGCCGGGTTGCGTCCCGAAACAGGGGATGGCAATCCGTATATCGGAAGACATCCTGAAAATGACCGG
ATTTTGTTTGCTGCCGGACATTTCAGAAACGGCATCCTCCTGGCACCTGCAACCGGTGAGATGATGGCAGACATGATCCT
CGGCAATCCGGTCAAAACAGAGTGGATCGAGGCGTTTAAAGCGGAGCGAAAGGAGGCTGTGCACAGGTGA

Upstream 100 bases:

>100_bases
AAAATGGCAGACGGCATCGCCGTGATGTCGGGGATCTTTTCCCATGACAGACCGAATGAGGCGGCCGCGCGGCTTGCCAG
TCTCGCGAAGGGAGATTCAT

Downstream 100 bases:

>100_bases
ACATTCAGCTCAACGGCCGGAAAATAGAGTGGAGAGACGACGGCGGCACGATTTATGATTTGCTCGCATCCTACAATTTG
GAAAATCGTGTTGTCGTTGT

Product: GoxB

Products: NA

Alternate protein names: GO [H]

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MRKRYDTIVIGGGIIGTSIAYHLAKAGKKTAVFESGEVGKKATSAAAGMLGAHAECDKPGTFFEFARASQKAYKRLTGEL
KDISGIDIRRHDGGILKLAFSESDREHLMQMGALDSVEWLEADEVYKLEPNAGKGILGANFIRDDVHVEPAAVCRAFARG
ARMLGADVFEYTPVLSIESEAGAVRVTSASGTAEAEHAVIASGVWSGALFKQIGLDKRFYPVKGECLSVWNDGISLTRTL
YHDHCYIVPRHSGRLVVGATMKPGDWNEQPELGGIEELIRKAKSMLPGIESMKIDQCWAGLRPETGDGNPYIGRHPENDR
ILFAAGHFRNGILLAPATGEMMADMILGNPVKTEWIEAFKAERKEAVHR

Sequences:

>Translated_369_residues
MRKRYDTIVIGGGIIGTSIAYHLAKAGKKTAVFESGEVGKKATSAAAGMLGAHAECDKPGTFFEFARASQKAYKRLTGEL
KDISGIDIRRHDGGILKLAFSESDREHLMQMGALDSVEWLEADEVYKLEPNAGKGILGANFIRDDVHVEPAAVCRAFARG
ARMLGADVFEYTPVLSIESEAGAVRVTSASGTAEAEHAVIASGVWSGALFKQIGLDKRFYPVKGECLSVWNDGISLTRTL
YHDHCYIVPRHSGRLVVGATMKPGDWNEQPELGGIEELIRKAKSMLPGIESMKIDQCWAGLRPETGDGNPYIGRHPENDR
ILFAAGHFRNGILLAPATGEMMADMILGNPVKTEWIEAFKAERKEAVHR
>Mature_369_residues
MRKRYDTIVIGGGIIGTSIAYHLAKAGKKTAVFESGEVGKKATSAAAGMLGAHAECDKPGTFFEFARASQKAYKRLTGEL
KDISGIDIRRHDGGILKLAFSESDREHLMQMGALDSVEWLEADEVYKLEPNAGKGILGANFIRDDVHVEPAAVCRAFARG
ARMLGADVFEYTPVLSIESEAGAVRVTSASGTAEAEHAVIASGVWSGALFKQIGLDKRFYPVKGECLSVWNDGISLTRTL
YHDHCYIVPRHSGRLVVGATMKPGDWNEQPELGGIEELIRKAKSMLPGIESMKIDQCWAGLRPETGDGNPYIGRHPENDR
ILFAAGHFRNGILLAPATGEMMADMILGNPVKTEWIEAFKAERKEAVHR

Specific function: Catalyzes the FAD-dependent oxidative deamination of various amines and D-amino acids to yield the corresponding alpha- keto acids, ammonia/amine, and hydrogen peroxide. Oxidizes sarcosine (N-methylglycine), N-ethylglycine and glycine. Can also oxidize th

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DAO family [H]

Homologues:

Organism=Homo sapiens, GI24797151, Length=384, Percent_Identity=27.6041666666667, Blast_Score=89, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI32563613, Length=373, Percent_Identity=26.2734584450402, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI20130091, Length=372, Percent_Identity=23.9247311827957, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR012727 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.4.3.19 [H]

Molecular weight: Translated: 40168; Mature: 40168

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKRYDTIVIGGGIIGTSIAYHLAKAGKKTAVFESGEVGKKATSAAAGMLGAHAECDKPG
CCCCCCEEEEECCHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCCCCC
TFFEFARASQKAYKRLTGELKDISGIDIRRHDGGILKLAFSESDREHLMQMGALDSVEWL
HHHHHHHHHHHHHHHHHCHHHCCCCCEEEECCCCEEEEEECCCHHHHHHHHCCCCCHHHC
EADEVYKLEPNAGKGILGANFIRDDVHVEPAAVCRAFARGARMLGADVFEYTPVLSIESE
CCCCEEEECCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHCCCEEEEECC
AGAVRVTSASGTAEAEHAVIASGVWSGALFKQIGLDKRFYPVKGECLSVWNDGISLTRTL
CCEEEEECCCCCCCCCHHEEECCHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCHHHHHEE
YHDHCYIVPRHSGRLVVGATMKPGDWNEQPELGGIEELIRKAKSMLPGIESMKIDQCWAG
ECCEEEEEECCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHCC
LRPETGDGNPYIGRHPENDRILFAAGHFRNGILLAPATGEMMADMILGNPVKTEWIEAFK
CCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEECCCHHHHHHHHHCCCCHHHHHHHHH
AERKEAVHR
HHHHHHCCC
>Mature Secondary Structure
MRKRYDTIVIGGGIIGTSIAYHLAKAGKKTAVFESGEVGKKATSAAAGMLGAHAECDKPG
CCCCCCEEEEECCHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCCCCC
TFFEFARASQKAYKRLTGELKDISGIDIRRHDGGILKLAFSESDREHLMQMGALDSVEWL
HHHHHHHHHHHHHHHHHCHHHCCCCCEEEECCCCEEEEEECCCHHHHHHHHCCCCCHHHC
EADEVYKLEPNAGKGILGANFIRDDVHVEPAAVCRAFARGARMLGADVFEYTPVLSIESE
CCCCEEEECCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHCCCEEEEECC
AGAVRVTSASGTAEAEHAVIASGVWSGALFKQIGLDKRFYPVKGECLSVWNDGISLTRTL
CCEEEEECCCCCCCCCHHEEECCHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCHHHHHEE
YHDHCYIVPRHSGRLVVGATMKPGDWNEQPELGGIEELIRKAKSMLPGIESMKIDQCWAG
ECCEEEEEECCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHCC
LRPETGDGNPYIGRHPENDRILFAAGHFRNGILLAPATGEMMADMILGNPVKTEWIEAFK
CCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEECCCHHHHHHHHHCCCCHHHHHHHHH
AERKEAVHR
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 9827558; 11744710 [H]