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The map label for this gene is citT [H]

Identifier: 52785015

GI number: 52785015

Start: 1256289

End: 1257005

Strand: Reverse

Name: citT [H]

Synonym: BLi01244

Alternate gene names: 52785015

Gene position: 1257005-1256289 (Counterclockwise)

Preceding gene: 52785016

Following gene: 52785003

Centisome position: 29.77

GC content: 47.56

Gene sequence:

>717_bases
ATGAAAGCATTACAAGTATTTATCGTAGAGGATGACATCAGAAACGCTGACATCCACCAAAAACTGATCAGCAAAATTGA
TGGATTTTCTGTCATTGGAATCGCGGAAAATTTTCAAGATGCAAAAGATTTGCTTCCGGACGTGAAGCCCGACCTTGTCC
TGCTCGACATTTTTCTGCCGGACGGCTCCGGCATGGAGCTTCTCTGGCTGATCAGACAAACGCTCAGGCATACAGACGTC
ATGATGATTACGGCGGCTAAGGAAGTCGAATATGTTGAACAGGCGATTCGCGCGGGAGCCGTCGATTATTTGATCAAGCC
GATTATGTTTTCCAGGCTGAAAGAAACGCTGTTAAACTATCGGTCTTACCGGCTCAAAGTAAATGAAATGTCTTCAATCG
ACCAGACAGACGTTGACAGCCTGATGGCAAAAAGGCGGAGCATCACGAAAGAACAAATTGCTAAAGCCGATTATCCGAAA
GGAATCGACGGACTGACGCTGAAAAAAGTAGCCGGCGTTTTAAACAAAAGCGAAAACAGCGATGGCATCACCGCCGAAAG
CCTCGGGCGCACCATCGGTGTCAGCCGGACGACCGCAAGGCGCTATTTAGAATTTTTAGCTGCCGAAAAGCATGTAAAAA
CAGAACTTTACTATGGAACCGTCGGGCGGCCCGAACGGCGCTACAAGCCCGTAAAAAATGAAAGTCCGGAAACGTAG

Upstream 100 bases:

>100_bases
AATGCGTTAAACGGGCAAATTAAAGCGGACAAAAGCGACCTTGGCGGAGCATTGTTTACTGTCGTGATACCAAAATAGAG
AAACGCTGGGGGACTGACCT

Downstream 100 bases:

>100_bases
CGTTCCGGACATCGACAGCTTAGCCTTCCAAATCGATCGACTTTTTATTTCTGTTCTTCATTGCCCGGGAAATCGGCGGC
ACGATGAGAGACAATAGAGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MKALQVFIVEDDIRNADIHQKLISKIDGFSVIGIAENFQDAKDLLPDVKPDLVLLDIFLPDGSGMELLWLIRQTLRHTDV
MMITAAKEVEYVEQAIRAGAVDYLIKPIMFSRLKETLLNYRSYRLKVNEMSSIDQTDVDSLMAKRRSITKEQIAKADYPK
GIDGLTLKKVAGVLNKSENSDGITAESLGRTIGVSRTTARRYLEFLAAEKHVKTELYYGTVGRPERRYKPVKNESPET

Sequences:

>Translated_238_residues
MKALQVFIVEDDIRNADIHQKLISKIDGFSVIGIAENFQDAKDLLPDVKPDLVLLDIFLPDGSGMELLWLIRQTLRHTDV
MMITAAKEVEYVEQAIRAGAVDYLIKPIMFSRLKETLLNYRSYRLKVNEMSSIDQTDVDSLMAKRRSITKEQIAKADYPK
GIDGLTLKKVAGVLNKSENSDGITAESLGRTIGVSRTTARRYLEFLAAEKHVKTELYYGTVGRPERRYKPVKNESPET
>Mature_238_residues
MKALQVFIVEDDIRNADIHQKLISKIDGFSVIGIAENFQDAKDLLPDVKPDLVLLDIFLPDGSGMELLWLIRQTLRHTDV
MMITAAKEVEYVEQAIRAGAVDYLIKPIMFSRLKETLLNYRSYRLKVNEMSSIDQTDVDSLMAKRRSITKEQIAKADYPK
GIDGLTLKKVAGVLNKSENSDGITAESLGRTIGVSRTTARRYLEFLAAEKHVKTELYYGTVGRPERRYKPVKNESPET

Specific function: Member of the two-component regulatory system CitT/CitS. Regulates the expression of the citM-yflN operon. Phosphorylated CitT binds to the citM promoter to activate the transcription of the citM-yflN operon [H]

COG id: COG4565

COG function: function code KT; Response regulator of citrate/malate metabolism

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786838, Length=227, Percent_Identity=39.2070484581498, Blast_Score=154, Evalue=6e-39,
Organism=Escherichia coli, GI1790566, Length=228, Percent_Identity=29.8245614035088, Blast_Score=122, Evalue=1e-29,
Organism=Escherichia coli, GI1788550, Length=126, Percent_Identity=33.3333333333333, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR013196
- InterPro:   IPR001789 [H]

Pfam domain/function: PF08279 HTH_11; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 26936; Mature: 26936

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALQVFIVEDDIRNADIHQKLISKIDGFSVIGIAENFQDAKDLLPDVKPDLVLLDIFLP
CCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCCCCCCEEEEEEEEC
DGSGMELLWLIRQTLRHTDVMMITAAKEVEYVEQAIRAGAVDYLIKPIMFSRLKETLLNY
CCCCHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSYRLKVNEMSSIDQTDVDSLMAKRRSITKEQIAKADYPKGIDGLTLKKVAGVLNKSENS
HHHEEEEHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCC
DGITAESLGRTIGVSRTTARRYLEFLAAEKHVKTELYYGTVGRPERRYKPVKNESPET
CCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHCCCCCCCCCCC
>Mature Secondary Structure
MKALQVFIVEDDIRNADIHQKLISKIDGFSVIGIAENFQDAKDLLPDVKPDLVLLDIFLP
CCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCCCCCCEEEEEEEEC
DGSGMELLWLIRQTLRHTDVMMITAAKEVEYVEQAIRAGAVDYLIKPIMFSRLKETLLNY
CCCCHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSYRLKVNEMSSIDQTDVDSLMAKRRSITKEQIAKADYPKGIDGLTLKKVAGVLNKSENS
HHHEEEEHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCC
DGITAESLGRTIGVSRTTARRYLEFLAAEKHVKTELYYGTVGRPERRYKPVKNESPET
CCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377; 10972810 [H]