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The map label for this gene is cotH [H]

Identifier: 52784940

GI number: 52784940

Start: 1175662

End: 1176738

Strand: Reverse

Name: cotH [H]

Synonym: BLi01168

Alternate gene names: 52784940

Gene position: 1176738-1175662 (Counterclockwise)

Preceding gene: 52784945

Following gene: 52784939

Centisome position: 27.87

GC content: 43.92

Gene sequence:

>1077_bases
ATGATGAGTGCCACTGCCTTGCCGGCCTTTAGGCTGCACATTCATCCGAAGCATCTGCTTGAGTTGAAAAAAGACGTCTG
GAGTGATGAAGCCGTTCCCGGCATGCTCTTGACCGGTTCAGCAAAGACGCCTGTCGCAGTGTCATACAGAGGGGCCCACA
CCCGCAAACTGACGAAAAAATCCTATTTCATTCAATATCCGGACAATAAAGAAAAGGCTGCGTTTCATTTGAACGCGGAA
TATCATGATCCGTCTTTCATCAGAAACAGGCTTTCCTTTCATTTTTTTGAACAAATCGGCGTCCTTGCGCCAGCAGCATC
ACACGTTTTCCTTTATATCAATGAAAAAAAAGAAGGCATCTATTTAAAAATCGAATCTGTTGACGATCATTTCTTAAAGA
GGAGAAATTTAGAAAGGGGGGCCATTTATTATGCCGTTGATGACGATGCTAATTTTTCTCTGCTGAGTTCCTTCAATAAA
AAGGCTAAGCAAAATCTCATGCAGGGATACGAAAGAAAAACGGGTTCAAGCCGCCACGATGACTACCTCCATGAGTTTAT
CTACTTTATCAATACCGCCAAAGACGACATATTTGAAAAAGAAATCAAACGCTATCTCGATGTCAAACAATATTTGCTGT
GGCTCATCGGCGCCGTCTGCACCCAAAATTTCGACGGCTTTGTCCATAATTACGCGCTTTATTTAAACGGTCGCACAAAA
ACGTTTCAAATCATTCCATGGGATTATGACGCGACATGGGGACGGAATATTCACGGGGAAGAAATGGAGCACAACCGGAT
TCCGGCGAAAGGCTATAATACGCTGTCTGCAAGGCTGCTCGACATCCCGGCTTTTCAATCCCAATACTTTAATTTAATGA
AAAATGTCTTGCACCGCCAATTTACAATCAGCCGGCTTTCGCGGTATGCGGTAAACTGGCACGAGACAATCGCGCCTTTT
CTTGAACATGATCCTTATACAACCGTCACATACAGCCGGCTCGAAGATGAGCAAAAACAAATTTTTCATTTCATCGATCA
GAGGAAGCGGTTCCTGCTTTTCGAGCTTTCCCGATAA

Upstream 100 bases:

>100_bases
TGTACTGAGGCAAATGACTGTTTTTGTTCAAACTTAGGCGGTCTGCTTCCGGGACAGGTTTTTTTCACATATGATATGTC
AGCTGAAAAAGGAGGAAATG

Downstream 100 bases:

>100_bases
TAGACTGTCGCTGTCCTCCGAAAAAAATGTCACATTTTTTGTCATATTGGCGAAAAAAATCCCTTTTACACAAAATAAGG
TATACTAGCAATATCAAGGA

Product: CotH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MMSATALPAFRLHIHPKHLLELKKDVWSDEAVPGMLLTGSAKTPVAVSYRGAHTRKLTKKSYFIQYPDNKEKAAFHLNAE
YHDPSFIRNRLSFHFFEQIGVLAPAASHVFLYINEKKEGIYLKIESVDDHFLKRRNLERGAIYYAVDDDANFSLLSSFNK
KAKQNLMQGYERKTGSSRHDDYLHEFIYFINTAKDDIFEKEIKRYLDVKQYLLWLIGAVCTQNFDGFVHNYALYLNGRTK
TFQIIPWDYDATWGRNIHGEEMEHNRIPAKGYNTLSARLLDIPAFQSQYFNLMKNVLHRQFTISRLSRYAVNWHETIAPF
LEHDPYTTVTYSRLEDEQKQIFHFIDQRKRFLLFELSR

Sequences:

>Translated_358_residues
MMSATALPAFRLHIHPKHLLELKKDVWSDEAVPGMLLTGSAKTPVAVSYRGAHTRKLTKKSYFIQYPDNKEKAAFHLNAE
YHDPSFIRNRLSFHFFEQIGVLAPAASHVFLYINEKKEGIYLKIESVDDHFLKRRNLERGAIYYAVDDDANFSLLSSFNK
KAKQNLMQGYERKTGSSRHDDYLHEFIYFINTAKDDIFEKEIKRYLDVKQYLLWLIGAVCTQNFDGFVHNYALYLNGRTK
TFQIIPWDYDATWGRNIHGEEMEHNRIPAKGYNTLSARLLDIPAFQSQYFNLMKNVLHRQFTISRLSRYAVNWHETIAPF
LEHDPYTTVTYSRLEDEQKQIFHFIDQRKRFLLFELSR
>Mature_358_residues
MMSATALPAFRLHIHPKHLLELKKDVWSDEAVPGMLLTGSAKTPVAVSYRGAHTRKLTKKSYFIQYPDNKEKAAFHLNAE
YHDPSFIRNRLSFHFFEQIGVLAPAASHVFLYINEKKEGIYLKIESVDDHFLKRRNLERGAIYYAVDDDANFSLLSSFNK
KAKQNLMQGYERKTGSSRHDDYLHEFIYFINTAKDDIFEKEIKRYLDVKQYLLWLIGAVCTQNFDGFVHNYALYLNGRTK
TFQIIPWDYDATWGRNIHGEEMEHNRIPAKGYNTLSARLLDIPAFQSQYFNLMKNVLHRQFTISRLSRYAVNWHETIAPF
LEHDPYTTVTYSRLEDEQKQIFHFIDQRKRFLLFELSR

Specific function: Involved in the assembly of several proteins in the inner and outer layer of the spore coat. Stabilizes CotC and CotU in the mother cell compartment of sporulating cells and promotes the assembly of both early and late forms of CotC-related polypeptides o

COG id: COG5337

COG function: function code M; Spore coat assembly protein

Gene ontology:

Cell location: Spore wall, spore coat [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CotH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014867 [H]

Pfam domain/function: PF08757 CotH [H]

EC number: NA

Molecular weight: Translated: 42255; Mature: 42255

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSATALPAFRLHIHPKHLLELKKDVWSDEAVPGMLLTGSAKTPVAVSYRGAHTRKLTKK
CCCCCCCCEEEEEECHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEEEECCCHHHHHHCC
SYFIQYPDNKEKAAFHLNAEYHDPSFIRNRLSFHFFEQIGVLAPAASHVFLYINEKKEGI
EEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCE
YLKIESVDDHFLKRRNLERGAIYYAVDDDANFSLLSSFNKKAKQNLMQGYERKTGSSRHD
EEEEECCCHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
DYLHEFIYFINTAKDDIFEKEIKRYLDVKQYLLWLIGAVCTQNFDGFVHNYALYLNGRTK
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCE
TFQIIPWDYDATWGRNIHGEEMEHNRIPAKGYNTLSARLLDIPAFQSQYFNLMKNVLHRQ
EEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHEEECCHHHHHHHHHHHHHHHHH
FTISRLSRYAVNWHETIAPFLEHDPYTTVTYSRLEDEQKQIFHFIDQRKRFLLFELSR
HHHHHHHHHHCCHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHCCEEEEEEECC
>Mature Secondary Structure
MMSATALPAFRLHIHPKHLLELKKDVWSDEAVPGMLLTGSAKTPVAVSYRGAHTRKLTKK
CCCCCCCCEEEEEECHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEEEECCCHHHHHHCC
SYFIQYPDNKEKAAFHLNAEYHDPSFIRNRLSFHFFEQIGVLAPAASHVFLYINEKKEGI
EEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCE
YLKIESVDDHFLKRRNLERGAIYYAVDDDANFSLLSSFNKKAKQNLMQGYERKTGSSRHD
EEEEECCCHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
DYLHEFIYFINTAKDDIFEKEIKRYLDVKQYLLWLIGAVCTQNFDGFVHNYALYLNGRTK
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCE
TFQIIPWDYDATWGRNIHGEEMEHNRIPAKGYNTLSARLLDIPAFQSQYFNLMKNVLHRQ
EEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHEEECCHHHHHHHHHHHHHHHHH
FTISRLSRYAVNWHETIAPFLEHDPYTTVTYSRLEDEQKQIFHFIDQRKRFLLFELSR
HHHHHHHHHHCCHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8755863; 8991897; 9353933; 9384377; 7814326; 10198031 [H]