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The map label for this gene is epr [H]

Identifier: 52784895

GI number: 52784895

Start: 1122420

End: 1124195

Strand: Reverse

Name: epr [H]

Synonym: BLi01123

Alternate gene names: 52784895

Gene position: 1124195-1122420 (Counterclockwise)

Preceding gene: 52784897

Following gene: 52784892

Centisome position: 26.62

GC content: 50.17

Gene sequence:

>1776_bases
ATGAAAAAGTTATGGAAAATCGCGGTTTCGGCTGCAATGTTCGTCGGTTTTTTCGCAAATTCACCCCGCATTCAAGCGGA
AAGCAATAAGCAGGAAAACGAGGTCATTGTTGTATATAAAAATACCAGCGGAAAAGAAACCGTCATCGAACAGGCAGACA
CGGTAGAACACGTTTACCGGCACATTCCCGCAGCCGCTGTCACTGCGGACGACAAAACAGTGCGCGAACTTGAACACGAT
CCCGACGTCCTGTATGTCGAAGACAACCTCCCGGTAGCTGCTGCCGACAGCACCGCTCTAAAAGCTTTCTCCAGCAGCAC
AGCGCAAAACGCCTCCGCGTTTTCACAGTGGAACATCAAGCTGATTCAAGCCGCACTGGCTTGGAATAAAGGTTTGACCG
GAAAACAGGTGAAGATCGCGGTTATTGACAGCGGGATTTCCCCCCATGAGGAGCTGTCGATCGCCGGCGGTGCATCGATG
GTCGGCTATACCGCTTCATACCGTGACGATAATGGCCACGGAACCCATGTTGCCGGAATCATCGGAGCGAAGCATAACGG
ACGGGGGATCGACGGCATCGCGCCCGGCGCGCAGCTGTATGCCGTAAAAGCGCTGGACCGGAATGGTGCGGGGGATCTGA
AAGGTATCTTACAAGGCATCGATTGGTCGATCCAGCACGGAATCGATATCATCAATATGAGCCTCGTCGTTTCAGGCGAC
AGTCAAGTTCTCCACGATGCAGTAGATAAAGCATACAAACGGGGAATCATTTTAGTCGGAGCGAGCGGAAATGCCGGAAA
CGGAAAATCCGTTTATTACCCGGCCGCCTACAGCAGCGTCATTGCCGTCTCGGCAACCAATGAAAAAAATCAGATCGCCT
CATTTTCCAACACCGGCAGCGCCGTCGAGTTTTCCGCTCCCGGCACATCGATTATCAGTACATCTTCCGATCGCGGCTAT
GCAATCGGAAGCGGCACTTCACAGGCAACGCCGCACGTCACCGGCATGTTTGCACTTTTGAAACAGCTGTACCCAACCGC
TTCAAATGCTGAGCTGCGCAAGAAAATGCAGTTTTATACAAGCGATTTGGGCGCTCCCGGCCGTGATCATTTGTTCGGCT
ACGGATTAATCCGCTTCAAAGAGGTCACACAGCCATTGGAAAAAGCGCAAAAAGCCGTCGGACAAGCGGAAAAGACAAAG
AAAAAAGCGGACATTCAAACCGCACAAAAAGCGATCGAACCGCTCCCTGCAGACGCAGATAAAACCGCTTTGAAAAAGAG
ACTCAATACTGTTAAAGAGCAGCTTAAAAAAACAGCCGAAAGCAAAGTGAAACTCGCTGAGAAGCAAAAAAAGAAAACCA
ATGCCGACTCCGCCCAAAAAGCGGTCAACGAACTCGACAGCGGCACTTTCAAAACGAATTTGCAAAAACGGATCAACGCG
GTCCGTTCAAGCCTCTTGAAGACCGCAAAGCAGGCCGTTGCCAAAGCTGAAAAAGCGGCAACAGACTCAAACCTCGGCAA
AGCGCAAAAAGCGATCAATGAGCTTCCCGCCGGAAAAGACAAATCAAATCTGCAAAAAAGGCTGAACACCGCGAAAAAGC
AAGCAGCTGCAGCCTATAATAAAAAAGTTTCTGCAGCAAAGGCCAAAGTCAAAACGGCCGAACAAAAGAGAACGAAAAAA
ACAAAATCAGCAGCGCAATCAGCAGTAGGCAAGCTGAAAGCATCCGCCGAAAAAACGAAGCTGCAAAAACGGATCAATGC
CATTAAGCTGAAGTAG

Upstream 100 bases:

>100_bases
TGCATGACAAGCGACCTTAAGATAAGCTTTCTTTCTCTTTGAAAATTCAAAAATCCTCCGATATATATAGCGAACGCCGC
TAAAAAAGGAGGAGAGCCGG

Downstream 100 bases:

>100_bases
TACGGAAAAAAGCCCGGAATCATCCGGGCCTTTTAATTTTCATATTTAGCAAATGCGTCATTATTGATGCTGTTGTACTA
ATTGACATTTCGGGCTCGTC

Product: Epr

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 591; Mature: 591

Protein sequence:

>591_residues
MKKLWKIAVSAAMFVGFFANSPRIQAESNKQENEVIVVYKNTSGKETVIEQADTVEHVYRHIPAAAVTADDKTVRELEHD
PDVLYVEDNLPVAAADSTALKAFSSSTAQNASAFSQWNIKLIQAALAWNKGLTGKQVKIAVIDSGISPHEELSIAGGASM
VGYTASYRDDNGHGTHVAGIIGAKHNGRGIDGIAPGAQLYAVKALDRNGAGDLKGILQGIDWSIQHGIDIINMSLVVSGD
SQVLHDAVDKAYKRGIILVGASGNAGNGKSVYYPAAYSSVIAVSATNEKNQIASFSNTGSAVEFSAPGTSIISTSSDRGY
AIGSGTSQATPHVTGMFALLKQLYPTASNAELRKKMQFYTSDLGAPGRDHLFGYGLIRFKEVTQPLEKAQKAVGQAEKTK
KKADIQTAQKAIEPLPADADKTALKKRLNTVKEQLKKTAESKVKLAEKQKKKTNADSAQKAVNELDSGTFKTNLQKRINA
VRSSLLKTAKQAVAKAEKAATDSNLGKAQKAINELPAGKDKSNLQKRLNTAKKQAAAAYNKKVSAAKAKVKTAEQKRTKK
TKSAAQSAVGKLKASAEKTKLQKRINAIKLK

Sequences:

>Translated_591_residues
MKKLWKIAVSAAMFVGFFANSPRIQAESNKQENEVIVVYKNTSGKETVIEQADTVEHVYRHIPAAAVTADDKTVRELEHD
PDVLYVEDNLPVAAADSTALKAFSSSTAQNASAFSQWNIKLIQAALAWNKGLTGKQVKIAVIDSGISPHEELSIAGGASM
VGYTASYRDDNGHGTHVAGIIGAKHNGRGIDGIAPGAQLYAVKALDRNGAGDLKGILQGIDWSIQHGIDIINMSLVVSGD
SQVLHDAVDKAYKRGIILVGASGNAGNGKSVYYPAAYSSVIAVSATNEKNQIASFSNTGSAVEFSAPGTSIISTSSDRGY
AIGSGTSQATPHVTGMFALLKQLYPTASNAELRKKMQFYTSDLGAPGRDHLFGYGLIRFKEVTQPLEKAQKAVGQAEKTK
KKADIQTAQKAIEPLPADADKTALKKRLNTVKEQLKKTAESKVKLAEKQKKKTNADSAQKAVNELDSGTFKTNLQKRINA
VRSSLLKTAKQAVAKAEKAATDSNLGKAQKAINELPAGKDKSNLQKRLNTAKKQAAAAYNKKVSAAKAKVKTAEQKRTKK
TKSAAQSAVGKLKASAEKTKLQKRINAIKLK
>Mature_591_residues
MKKLWKIAVSAAMFVGFFANSPRIQAESNKQENEVIVVYKNTSGKETVIEQADTVEHVYRHIPAAAVTADDKTVRELEHD
PDVLYVEDNLPVAAADSTALKAFSSSTAQNASAFSQWNIKLIQAALAWNKGLTGKQVKIAVIDSGISPHEELSIAGGASM
VGYTASYRDDNGHGTHVAGIIGAKHNGRGIDGIAPGAQLYAVKALDRNGAGDLKGILQGIDWSIQHGIDIINMSLVVSGD
SQVLHDAVDKAYKRGIILVGASGNAGNGKSVYYPAAYSSVIAVSATNEKNQIASFSNTGSAVEFSAPGTSIISTSSDRGY
AIGSGTSQATPHVTGMFALLKQLYPTASNAELRKKMQFYTSDLGAPGRDHLFGYGLIRFKEVTQPLEKAQKAVGQAEKTK
KKADIQTAQKAIEPLPADADKTALKKRLNTVKEQLKKTAESKVKLAEKQKKKTNADSAQKAVNELDSGTFKTNLQKRINA
VRSSLLKTAKQAVAKAEKAATDSNLGKAQKAINELPAGKDKSNLQKRLNTAKKQAAAAYNKKVSAAKAKVKTAEQKRTKK
TKSAAQSAVGKLKASAEKTKLQKRINAIKLK

Specific function: Unknown

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Homo sapiens, GI31317307, Length=284, Percent_Identity=29.5774647887324, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI4506775, Length=308, Percent_Identity=28.2467532467532, Blast_Score=82, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6319893, Length=222, Percent_Identity=34.2342342342342, Blast_Score=98, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6320775, Length=237, Percent_Identity=34.1772151898734, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6324576, Length=235, Percent_Identity=33.6170212765957, Blast_Score=94, Evalue=5e-20,
Organism=Drosophila melanogaster, GI45550681, Length=241, Percent_Identity=28.2157676348548, Blast_Score=73, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR009020
- InterPro:   IPR010259 [H]

Pfam domain/function: PF05922 Inhibitor_I9; PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 63010; Mature: 63010

Theoretical pI: Translated: 10.48; Mature: 10.48

Prosite motif: PS00136 SUBTILASE_ASP ; PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLWKIAVSAAMFVGFFANSPRIQAESNKQENEVIVVYKNTSGKETVIEQADTVEHVYR
CCHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHH
HIPAAAVTADDKTVRELEHDPDVLYVEDNLPVAAADSTALKAFSSSTAQNASAFSQWNIK
HCCCCEEECCCHHHHHHCCCCCEEEEECCCCEEECCHHHHHHHHCCCCCCHHHHHHCCHH
LIQAALAWNKGLTGKQVKIAVIDSGISPHEELSIAGGASMVGYTASYRDDNGHGTHVAGI
HHHHHHHHCCCCCCCEEEEEEEECCCCCHHHEEECCCCHHHEEEEECCCCCCCCCEEEEE
IGAKHNGRGIDGIAPGAQLYAVKALDRNGAGDLKGILQGIDWSIQHGIDIINMSLVVSGD
EECCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCHHHHCCCEEEEEEEEEECC
SQVLHDAVDKAYKRGIILVGASGNAGNGKSVYYPAAYSSVIAVSATNEKNQIASFSNTGS
HHHHHHHHHHHHHCCEEEEECCCCCCCCCEEEECCCCCCEEEEEECCCCHHHHCCCCCCC
AVEFSAPGTSIISTSSDRGYAIGSGTSQATPHVTGMFALLKQLYPTASNAELRKKMQFYT
EEEECCCCCEEEECCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
SDLGAPGRDHLFGYGLIRFKEVTQPLEKAQKAVGQAEKTKKKADIQTAQKAIEPLPADAD
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
KTALKKRLNTVKEQLKKTAESKVKLAEKQKKKTNADSAQKAVNELDSGTFKTNLQKRINA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHH
VRSSLLKTAKQAVAKAEKAATDSNLGKAQKAINELPAGKDKSNLQKRLNTAKKQAAAAYN
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
KKVSAAKAKVKTAEQKRTKKTKSAAQSAVGKLKASAEKTKLQKRINAIKLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKLWKIAVSAAMFVGFFANSPRIQAESNKQENEVIVVYKNTSGKETVIEQADTVEHVYR
CCHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHH
HIPAAAVTADDKTVRELEHDPDVLYVEDNLPVAAADSTALKAFSSSTAQNASAFSQWNIK
HCCCCEEECCCHHHHHHCCCCCEEEEECCCCEEECCHHHHHHHHCCCCCCHHHHHHCCHH
LIQAALAWNKGLTGKQVKIAVIDSGISPHEELSIAGGASMVGYTASYRDDNGHGTHVAGI
HHHHHHHHCCCCCCCEEEEEEEECCCCCHHHEEECCCCHHHEEEEECCCCCCCCCEEEEE
IGAKHNGRGIDGIAPGAQLYAVKALDRNGAGDLKGILQGIDWSIQHGIDIINMSLVVSGD
EECCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCHHHHCCCEEEEEEEEEECC
SQVLHDAVDKAYKRGIILVGASGNAGNGKSVYYPAAYSSVIAVSATNEKNQIASFSNTGS
HHHHHHHHHHHHHCCEEEEECCCCCCCCCEEEECCCCCCEEEEEECCCCHHHHCCCCCCC
AVEFSAPGTSIISTSSDRGYAIGSGTSQATPHVTGMFALLKQLYPTASNAELRKKMQFYT
EEEECCCCCEEEECCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
SDLGAPGRDHLFGYGLIRFKEVTQPLEKAQKAVGQAEKTKKKADIQTAQKAIEPLPADAD
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
KTALKKRLNTVKEQLKKTAESKVKLAEKQKKKTNADSAQKAVNELDSGTFKTNLQKRINA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHH
VRSSLLKTAKQAVAKAEKAATDSNLGKAQKAINELPAGKDKSNLQKRLNTAKKQAAAAYN
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
KKVSAAKAKVKTAEQKRTKKTKSAAQSAVGKLKASAEKTKLQKRINAIKLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2116590; 3142851; 7934828; 9384377 [H]