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The map label for this gene is yfmD [H]

Identifier: 52784884

GI number: 52784884

Start: 1112583

End: 1113581

Strand: Direct

Name: yfmD [H]

Synonym: BLi01112

Alternate gene names: 52784884

Gene position: 1112583-1113581 (Clockwise)

Preceding gene: 52784883

Following gene: 52784885

Centisome position: 26.35

GC content: 51.65

Gene sequence:

>999_bases
TTGATATATATGAAACGTTTTGCACCGCTCATTTTTGTTTTTCTTTTGCTTGCGAGTTTTGCGCTTTCTGTTTCAATCGG
TTCGTCAATGATTGCACTGTCCGATATTTGGGCGGCTGTTTTTGCGTACGACGGTTCAAAATTGCACGCGATTATTCAGT
CCATCCGAATTCCGCGCGCATTGACCGCCGCATTAATCGGCGCGAATCTAGGGGCTGCGGGCGCGCTGATGCAGGCGGTG
ACAAGAAATGCGCTCGCATCTCCGAGCATCTTCGGAATCAATGCAGGGGCCTCGCTTGCTGTCGTATGTTTGACGGTGAT
GTTTCCTGCGCTTGCAGCTCCCCAGACAGCGATGGGAGCCGCATTTGCCGGCGGTGCAGCGGCCGCGCTGATCGTGTACG
CGGTTGCCTCAGTATTCAGCGAACATGACAGGGATATCAGCTTTGCCTTGATTGGCGTTGTCATTCAGGCGATTCTTGCT
TCGATGACGCAAATGCTGCTTATCTTTCATGAAGAGTCGACGGAAACGCTATTGTTTTGGCTTTCCGGTTCTTTAGCGGG
GAGCTCATGGGATAAGCTTCATTTATTGGTTCCGGTGAGCATTGCGGGTTTGTTGACGGCTTTGGCCTTAGGGAGGGCGG
CTTCCGTCATGAGTCTCGGAGATGAAGTTTCTCATGGGCTGGGACAAAAAGTATGGCTCAGCAGATTGCTAATCGCCTTC
ACTGTTGTCGCATTGGCGGGAGTGTCCGTTTCCGCCGCCGGTCCGATTGGTTTCATCGGTTTGATGGTTCCTCATATGAT
CCGGTATCTCATCGGTGCTGACTACCGGGCGGTGATTCCGTATTCGGCATTGCTTGGAGCCGTTCTTTTGCTGTTTGCCG
ATATTTTGTCCCGCTTTGTCTATTTTCCGTACCAAACGCCTGTCGGAGTTGTCACGGCAATGATTGGGACGCCGTTTTTT
ATCTATTTGGCGAGAAGACGGAAAAAGGGGGCGGCATAA

Upstream 100 bases:

>100_bases
GATCAAAAGAAATCTTAGGAGCCTGCCGGCTTGTTGGACGGGATGACGCATGCTTTTGTAAAAAAGCATGCGCTTGTTTT
TTCTAAAGGAGTGACCTGTT

Downstream 100 bases:

>100_bases
TGAACAATCCGGCAAGAAAGACGAAAAGGCGGCGCGGACAATCGGCGGTTGTTCTCTGTGCGCTATTCGCCTGTTTGTTT
GTGCTCATTGTACTCAATTT

Product: YfmD

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric-citrate import system permease protein [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MIYMKRFAPLIFVFLLLASFALSVSIGSSMIALSDIWAAVFAYDGSKLHAIIQSIRIPRALTAALIGANLGAAGALMQAV
TRNALASPSIFGINAGASLAVVCLTVMFPALAAPQTAMGAAFAGGAAAALIVYAVASVFSEHDRDISFALIGVVIQAILA
SMTQMLLIFHEESTETLLFWLSGSLAGSSWDKLHLLVPVSIAGLLTALALGRAASVMSLGDEVSHGLGQKVWLSRLLIAF
TVVALAGVSVSAAGPIGFIGLMVPHMIRYLIGADYRAVIPYSALLGAVLLLFADILSRFVYFPYQTPVGVVTAMIGTPFF
IYLARRRKKGAA

Sequences:

>Translated_332_residues
MIYMKRFAPLIFVFLLLASFALSVSIGSSMIALSDIWAAVFAYDGSKLHAIIQSIRIPRALTAALIGANLGAAGALMQAV
TRNALASPSIFGINAGASLAVVCLTVMFPALAAPQTAMGAAFAGGAAAALIVYAVASVFSEHDRDISFALIGVVIQAILA
SMTQMLLIFHEESTETLLFWLSGSLAGSSWDKLHLLVPVSIAGLLTALALGRAASVMSLGDEVSHGLGQKVWLSRLLIAF
TVVALAGVSVSAAGPIGFIGLMVPHMIRYLIGADYRAVIPYSALLGAVLLLFADILSRFVYFPYQTPVGVVTAMIGTPFF
IYLARRRKKGAA
>Mature_332_residues
MIYMKRFAPLIFVFLLLASFALSVSIGSSMIALSDIWAAVFAYDGSKLHAIIQSIRIPRALTAALIGANLGAAGALMQAV
TRNALASPSIFGINAGASLAVVCLTVMFPALAAPQTAMGAAFAGGAAAALIVYAVASVFSEHDRDISFALIGVVIQAILA
SMTQMLLIFHEESTETLLFWLSGSLAGSSWDKLHLLVPVSIAGLLTALALGRAASVMSLGDEVSHGLGQKVWLSRLLIAF
TVVALAGVSVSAAGPIGFIGLMVPHMIRYLIGADYRAVIPYSALLGAVLLLFADILSRFVYFPYQTPVGVVTAMIGTPFF
IYLARRRKKGAA

Specific function: Part of the ABC transporter complex yfmCDEF involved in citrate-dependent Fe(3+) import. Involved in the translocation of the substrate across the membrane (Probable) [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790741, Length=280, Percent_Identity=38.9285714285714, Blast_Score=183, Evalue=1e-47,
Organism=Escherichia coli, GI1790740, Length=327, Percent_Identity=37.0030581039755, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI1786805, Length=283, Percent_Identity=40.9893992932862, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1786804, Length=340, Percent_Identity=34.7058823529412, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1788004, Length=278, Percent_Identity=34.5323741007194, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1786347, Length=288, Percent_Identity=30.5555555555556, Blast_Score=112, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 34779; Mature: 34779

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYMKRFAPLIFVFLLLASFALSVSIGSSMIALSDIWAAVFAYDGSKLHAIIQSIRIPRA
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHH
LTAALIGANLGAAGALMQAVTRNALASPSIFGINAGASLAVVCLTVMFPALAAPQTAMGA
HHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHCCCHHHHHH
AFAGGAAAALIVYAVASVFSEHDRDISFALIGVVIQAILASMTQMLLIFHEESTETLLFW
HHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
LSGSLAGSSWDKLHLLVPVSIAGLLTALALGRAASVMSLGDEVSHGLGQKVWLSRLLIAF
EECCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
TVVALAGVSVSAAGPIGFIGLMVPHMIRYLIGADYRAVIPYSALLGAVLLLFADILSRFV
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHH
YFPYQTPVGVVTAMIGTPFFIYLARRRKKGAA
HCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIYMKRFAPLIFVFLLLASFALSVSIGSSMIALSDIWAAVFAYDGSKLHAIIQSIRIPRA
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHH
LTAALIGANLGAAGALMQAVTRNALASPSIFGINAGASLAVVCLTVMFPALAAPQTAMGA
HHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHCCCHHHHHH
AFAGGAAAALIVYAVASVFSEHDRDISFALIGVVIQAILASMTQMLLIFHEESTETLLFW
HHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
LSGSLAGSSWDKLHLLVPVSIAGLLTALALGRAASVMSLGDEVSHGLGQKVWLSRLLIAF
EECCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
TVVALAGVSVSAAGPIGFIGLMVPHMIRYLIGADYRAVIPYSALLGAVLLLFADILSRFV
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHH
YFPYQTPVGVVTAMIGTPFFIYLARRRKKGAA
HCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377 [H]