Click here to switch to the map view.

The map label for this gene is serC [H]

Identifier: 52784854

GI number: 52784854

Start: 1080326

End: 1081399

Strand: Reverse

Name: serC [H]

Synonym: BLi01082

Alternate gene names: 52784854

Gene position: 1081399-1080326 (Counterclockwise)

Preceding gene: 52784855

Following gene: 52784853

Centisome position: 25.61

GC content: 48.32

Gene sequence:

>1074_bases
ATGATACGTACAACGAACTTTAACGCAGGACCAGCAGCACTGCCTTTAGAAGTGCTTCAGAAGGCAAAAGACGAATTTCT
TGATTTCAATGGTGCGGGGATGTCCGTGATGGAGCTGTCCCATCGCAGCAAAGAGTATGACGCCGTTCATCAAAAAGCGA
AAGCTCTGTTAAAAGAACTGATGGACATACCTGATGATTATGAAGTCATGTTTCTGCAAGGCGGAGCAAGCCTTCAGTTT
TCAATGATTCCGATGAACTTTCTCTCCAAAGACAAAACGGCCCACTTCATTATGACAGGCGCTTGGTCTGAAAAAGCGCT
GGCCGAAGCAAAGCTCTTCGGAAACACATCGATCATCGCGTCCAGCAAAGAAGATACGTACAGCTATATTCCTGAAGTAC
CGGAGATTCCGGCAGACGGGGCCTACCTTCACCTGACTTCCAACAATACGATCTTTGGAACGCAGTGGCAAAAGTTCCCC
GACGCTCCGATTCCGGTTGTCGCGGACATGTCCAGCGATATTTTAAGCAGAAAAATCGATGTTTCCCAATTTGACATCAT
CTATGCCGGCGCTCAGAAAAACCTCGGACCGTCAGGGGTGACCGTTGTCATCATGAAAAAAGACTGGCTCGGCAAGGAAA
ATGAGCAAGTTGCCAAAATTCTGAAGTACTCAACACATGCCAAAGCGGATTCGCTCTACAATACCCCTCCGACATTTGCG
ATTTATATGCTGTCTCTCGTGCTGGAGTGGCTCAAGGAAAAAGGAGGCCTCGATGCCATTGAGAAACGCAACCGCGAAAA
GGCCGGAATTTTATACAATGCGATCGACGAAAGCGGCGGATTCTACCGCGGCCATGCGAGAGAAGACAGCCGCTCAAACA
TGAACGTCACCTTTACGCTCAAAAATGATGAGCTGACAGCATCATTCATCGCAAAGGCAAAGGAAGAAAAAATGTCAGGG
CTTGGCGGACACCGTTCGGTCGGTGGCTGCCGCGCTTCGATTTACAATGCCGTATCAGTTGAAGACTGCGAAAAGCTGGC
TGCCTTTATGAAGAAATTCCGCGAAGAAAACTGA

Upstream 100 bases:

>100_bases
TTGCTCTATATTTCACACAATTCAAATTTTTTATGTATAACCGGAACCTTTTATGATAGGATTGTTTTATATTTTTATAC
ACGAACAGGGAGCGATTGTG

Downstream 100 bases:

>100_bases
TGTTTATCCTGATGATGGAAGATGGCGAAAAAGGCTTCCCCATTCCTTCGAAAGTTTGATATACTACTAGAAAGCTTTCG
CAATAAATGACGAGCATATT

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT; Vegetative protein 234; VEG234 [H]

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MIRTTNFNAGPAALPLEVLQKAKDEFLDFNGAGMSVMELSHRSKEYDAVHQKAKALLKELMDIPDDYEVMFLQGGASLQF
SMIPMNFLSKDKTAHFIMTGAWSEKALAEAKLFGNTSIIASSKEDTYSYIPEVPEIPADGAYLHLTSNNTIFGTQWQKFP
DAPIPVVADMSSDILSRKIDVSQFDIIYAGAQKNLGPSGVTVVIMKKDWLGKENEQVAKILKYSTHAKADSLYNTPPTFA
IYMLSLVLEWLKEKGGLDAIEKRNREKAGILYNAIDESGGFYRGHAREDSRSNMNVTFTLKNDELTASFIAKAKEEKMSG
LGGHRSVGGCRASIYNAVSVEDCEKLAAFMKKFREEN

Sequences:

>Translated_357_residues
MIRTTNFNAGPAALPLEVLQKAKDEFLDFNGAGMSVMELSHRSKEYDAVHQKAKALLKELMDIPDDYEVMFLQGGASLQF
SMIPMNFLSKDKTAHFIMTGAWSEKALAEAKLFGNTSIIASSKEDTYSYIPEVPEIPADGAYLHLTSNNTIFGTQWQKFP
DAPIPVVADMSSDILSRKIDVSQFDIIYAGAQKNLGPSGVTVVIMKKDWLGKENEQVAKILKYSTHAKADSLYNTPPTFA
IYMLSLVLEWLKEKGGLDAIEKRNREKAGILYNAIDESGGFYRGHAREDSRSNMNVTFTLKNDELTASFIAKAKEEKMSG
LGGHRSVGGCRASIYNAVSVEDCEKLAAFMKKFREEN
>Mature_357_residues
MIRTTNFNAGPAALPLEVLQKAKDEFLDFNGAGMSVMELSHRSKEYDAVHQKAKALLKELMDIPDDYEVMFLQGGASLQF
SMIPMNFLSKDKTAHFIMTGAWSEKALAEAKLFGNTSIIASSKEDTYSYIPEVPEIPADGAYLHLTSNNTIFGTQWQKFP
DAPIPVVADMSSDILSRKIDVSQFDIIYAGAQKNLGPSGVTVVIMKKDWLGKENEQVAKILKYSTHAKADSLYNTPPTFA
IYMLSLVLEWLKEKGGLDAIEKRNREKAGILYNAIDESGGFYRGHAREDSRSNMNVTFTLKNDELTASFIAKAKEEKMSG
LGGHRSVGGCRASIYNAVSVEDCEKLAAFMKKFREEN

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=362, Percent_Identity=45.5801104972376, Blast_Score=320, Evalue=1e-87,
Organism=Homo sapiens, GI10863955, Length=358, Percent_Identity=41.340782122905, Blast_Score=276, Evalue=2e-74,
Organism=Escherichia coli, GI1787136, Length=362, Percent_Identity=42.2651933701657, Blast_Score=288, Evalue=3e-79,
Organism=Caenorhabditis elegans, GI17506897, Length=364, Percent_Identity=43.6813186813187, Blast_Score=304, Evalue=5e-83,
Organism=Saccharomyces cerevisiae, GI6324758, Length=385, Percent_Identity=40.5194805194805, Blast_Score=271, Evalue=2e-73,
Organism=Drosophila melanogaster, GI21356589, Length=360, Percent_Identity=41.1111111111111, Blast_Score=303, Evalue=1e-82,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 39601; Mature: 39601

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRTTNFNAGPAALPLEVLQKAKDEFLDFNGAGMSVMELSHRSKEYDAVHQKAKALLKEL
CEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHH
MDIPDDYEVMFLQGGASLQFSMIPMNFLSKDKTAHFIMTGAWSEKALAEAKLFGNTSIIA
HCCCCCCEEEEEECCCCEEEEEECHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCCEEEE
SSKEDTYSYIPEVPEIPADGAYLHLTSNNTIFGTQWQKFPDAPIPVVADMSSDILSRKID
CCCCCHHHHCCCCCCCCCCCEEEEEECCCEEECCCCCCCCCCCCCEEECCHHHHHHHCCC
VSQFDIIYAGAQKNLGPSGVTVVIMKKDWLGKENEQVAKILKYSTHAKADSLYNTPPTFA
CCCEEEEEECCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHH
IYMLSLVLEWLKEKGGLDAIEKRNREKAGILYNAIDESGGFYRGHAREDSRSNMNVTFTL
HHHHHHHHHHHHHCCCCCHHHHCCCCCCCEEEEEECCCCCEEECCCCCCCCCCCEEEEEE
KNDELTASFIAKAKEEKMSGLGGHRSVGGCRASIYNAVSVEDCEKLAAFMKKFREEN
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIRTTNFNAGPAALPLEVLQKAKDEFLDFNGAGMSVMELSHRSKEYDAVHQKAKALLKEL
CEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHH
MDIPDDYEVMFLQGGASLQFSMIPMNFLSKDKTAHFIMTGAWSEKALAEAKLFGNTSIIA
HCCCCCCEEEEEECCCCEEEEEECHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCCEEEE
SSKEDTYSYIPEVPEIPADGAYLHLTSNNTIFGTQWQKFPDAPIPVVADMSSDILSRKID
CCCCCHHHHCCCCCCCCCCCEEEEEECCCEEECCCCCCCCCCCCCEEECCHHHHHHHCCC
VSQFDIIYAGAQKNLGPSGVTVVIMKKDWLGKENEQVAKILKYSTHAKADSLYNTPPTFA
CCCEEEEEECCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHH
IYMLSLVLEWLKEKGGLDAIEKRNREKAGILYNAIDESGGFYRGHAREDSRSNMNVTFTL
HHHHHHHHHHHHHCCCCCHHHHCCCCCCCEEEEEECCCCCEEECCCCCCCCCCCEEEEEE
KNDELTASFIAKAKEEKMSGLGGHRSVGGCRASIYNAVSVEDCEKLAAFMKKFREEN
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 9298659 [H]