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The map label for this gene is hpr

Identifier: 52784850

GI number: 52784850

Start: 1078042

End: 1078662

Strand: Reverse

Name: hpr

Synonym: BLi01078

Alternate gene names: 52784850

Gene position: 1078662-1078042 (Counterclockwise)

Preceding gene: 52784851

Following gene: 52784848

Centisome position: 25.54

GC content: 43.32

Gene sequence:

>621_bases
ATGAATCGAGCGGAAGAGCCCTATACGGTGAAAGAAGCCCTTTTATTCAGTCAAAGAATGGCACAGCTTAGCAAGGCGCT
TTGGAAGTCGATAGAAAAGGATTGGCAGCAGTGGATTAAACCTTATGATCTGAACATTAACGAGCACCATATTTTGTGGA
TCGCCTACCAGCTGAACGGAGCATCCATTTCAGAAATCGCCAAGTTCGGCGTCATGCACGTATCCACAGCGTTTAATTTT
TCAAAAAAGCTTGAGGAAAGAGGTTACCTGGAGTTTTCCAAAAAATTGAATGACAAACGCAACACTTACATTCAGCTGAC
TCCGAAAGGTGAAGAAGTTTTCCTTAAAATCCTCGAGTCTTACGATCCGACCCGGAACGCCGTCTTAAAAGGCGCTCAGC
CCCTTCATCAGCTGTACGGGAAGTTTCCAGAAATCGTCGAGATGATGTCGATCATCCGCCATATTTACGGCGATGATTTC
ATGGAAATTTTCGAAAAATCGTTTTCAAACATCGAAAATGAATTTACGAGCGAAGAGGGCAAAATGAAGAAAAAACAAGA
AGCAAAAGAAGCCGGGGAATCGATAGAGGTGGACAAACCGCTTGAGCCTCTTAAAAACTAA

Upstream 100 bases:

>100_bases
AAACTGGATTTTTTAAAAAATTCGTAAATTTACATCTTTATTAATCTTTATTTTATTGGCATAATAGAAATTATAAGATA
AAGAGAAGCAGGTGAAGTGA

Downstream 100 bases:

>100_bases
GCCAGATCGTACTGCCTGATAATGCTGATGAATTCGCTCATCAGCGGTTTGTAAAGACCTTGTCTGTGAAGGGCGAAAAT
CGTTTCGTGCACTTCAAGTT

Product: transcriptional regulator Hpr

Products: NA

Alternate protein names: Protease production regulatory protein hpr

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MNRAEEPYTVKEALLFSQRMAQLSKALWKSIEKDWQQWIKPYDLNINEHHILWIAYQLNGASISEIAKFGVMHVSTAFNF
SKKLEERGYLEFSKKLNDKRNTYIQLTPKGEEVFLKILESYDPTRNAVLKGAQPLHQLYGKFPEIVEMMSIIRHIYGDDF
MEIFEKSFSNIENEFTSEEGKMKKKQEAKEAGESIEVDKPLEPLKN

Sequences:

>Translated_206_residues
MNRAEEPYTVKEALLFSQRMAQLSKALWKSIEKDWQQWIKPYDLNINEHHILWIAYQLNGASISEIAKFGVMHVSTAFNF
SKKLEERGYLEFSKKLNDKRNTYIQLTPKGEEVFLKILESYDPTRNAVLKGAQPLHQLYGKFPEIVEMMSIIRHIYGDDF
MEIFEKSFSNIENEFTSEEGKMKKKQEAKEAGESIEVDKPLEPLKN
>Mature_206_residues
MNRAEEPYTVKEALLFSQRMAQLSKALWKSIEKDWQQWIKPYDLNINEHHILWIAYQLNGASISEIAKFGVMHVSTAFNF
SKKLEERGYLEFSKKLNDKRNTYIQLTPKGEEVFLKILESYDPTRNAVLKGAQPLHQLYGKFPEIVEMMSIIRHIYGDDF
MEIFEKSFSNIENEFTSEEGKMKKKQEAKEAGESIEVDKPLEPLKN

Specific function: Negative regulator of protease production and sporulation

COG id: COG1846

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HPR_BACLD (Q65LS8)

Other databases:

- EMBL:   CP000002
- EMBL:   AE017333
- RefSeq:   YP_078277.1
- RefSeq:   YP_090679.1
- HSSP:   P11065
- ProteinModelPortal:   Q65LS8
- SMR:   Q65LS8
- STRING:   Q65LS8
- EnsemblBacteria:   EBBACT00000055278
- EnsemblBacteria:   EBBACT00000061384
- GeneID:   3030006
- GeneID:   3098232
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi01078
- KEGG:   bli:BL02906
- NMPDR:   fig|279010.5.peg.1977
- eggNOG:   COG1846
- GeneTree:   EBGT00050000001224
- HOGENOM:   HBG313781
- OMA:   NEHHILW
- ProtClustDB:   PRK13777
- BioCyc:   BLIC279010-1:BLI01078-MONOMER
- BioCyc:   BLIC279010:BL02906-MONOMER
- GO:   GO:0005622
- HAMAP:   MF_01911
- InterPro:   IPR000835
- InterPro:   IPR023187
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- SMART:   SM00347

Pfam domain/function: PF01047 MarR

EC number: NA

Molecular weight: Translated: 24129; Mature: 24129

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS01117 HTH_MARR_1; PS50995 HTH_MARR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRAEEPYTVKEALLFSQRMAQLSKALWKSIEKDWQQWIKPYDLNINEHHILWIAYQLNG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECC
ASISEIAKFGVMHVSTAFNFSKKLEERGYLEFSKKLNDKRNTYIQLTPKGEEVFLKILES
CCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHH
YDPTRNAVLKGAQPLHQLYGKFPEIVEMMSIIRHIYGDDFMEIFEKSFSNIENEFTSEEG
CCCHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
KMKKKQEAKEAGESIEVDKPLEPLKN
HHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNRAEEPYTVKEALLFSQRMAQLSKALWKSIEKDWQQWIKPYDLNINEHHILWIAYQLNG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECC
ASISEIAKFGVMHVSTAFNFSKKLEERGYLEFSKKLNDKRNTYIQLTPKGEEVFLKILES
CCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHH
YDPTRNAVLKGAQPLHQLYGKFPEIVEMMSIIRHIYGDDFMEIFEKSFSNIENEFTSEEG
CCCHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
KMKKKQEAKEAGESIEVDKPLEPLKN
HHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA