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The map label for this gene is sdcS [H]

Identifier: 52784558

GI number: 52784558

Start: 768678

End: 770102

Strand: Direct

Name: sdcS [H]

Synonym: BLi00759

Alternate gene names: 52784558

Gene position: 768678-770102 (Clockwise)

Preceding gene: 52784557

Following gene: 52784559

Centisome position: 18.2

GC content: 48.35

Gene sequence:

>1425_bases
ATGAGAGTATATACAACGACTAAACTGACCGGATTGTTATTGGGGCCGATCAGTTTTTTGCTGATTCTCGGCTTGATACC
GGAAGCTGAGCTGGCTTACGCGCCGCGAATCGTTCTTGCGGTTACAGCCTGGACGGCCGTCTGGTGGATTACGGAAGCCG
TGCCGATTCCGGCGGCATCGCTCTTGCCAGTCATTTTGCTGCCGACATTGGGTGGTTTAGATATGGAAACGACGGCCAAA
GCATACGGCGATCCGATTGTGTTTATGTATATGGGGGGATTTATCATTGCGATCGCCATCGAAAAATGGAATCTTCATAA
ACGGATGGCTTTGCACATTTTAAAGCGGATCGGGGCTGAAAGCCACCGGATCGTGCTTGGCGTGATGGCGGCGACTGCGT
TTTTATCGATGTGGATTTCGAATGCTGCCACCGCTTTGATGATGCTTCCCGTAGCGCTAGCAGTCATTAAAGAAGTGCAG
GAAAAAGAAATTTTAAAAGGCGAATCGCTGCAGAAGTTCAGCAAAAGCATTTTGCTGGCTGTCGCGTATGCGGCGTCGAT
CGGCGGACTTGCCACATTGGTCGGTTCCGTTCCGAACGCGGTGTTTGCCGCGATGTCCAAGCAGATGCTCAATCACGAAA
TTATGTTTTTTGAATGGTTTTTATTCGGGTTCCCGGTTTCCATTCTGTTTCTTGCCATTTTATATGTTTATTTAACGAAA
ATAAAATTTAAAGTGAGCGCTTTTCAAGGAAAAAAGCCTGATTTTATCGATCATGATTTAAAGGCGCTTGGCGCAATGAC
GAGGGAGGAAAAATCGGTTTTTACCGTTTTTTTATTAACCGCATGTTTGTGGATGTTCAAATTTATCCTTCCGTTTCAAA
TATCAGATACGTCGATCGCGATTTTCGGAGCGGTTCTGCTGTTTTTAATTCCGAGTACAAAGGATGAACGGATTTTGGAA
TGGAAGGATATGCAGTCGCTGCCATGGGGACTGCTTCTATTGTTTGGAGGCGGCTTGTCGCTTGCGGCCGGTTTTTCGGC
GACCAATCTGACAGCATGGATCGGCGGCAAGCTCAAGCTGTTGGAAGGCCACCCTTACTTATTTGTCCTGATTATTTTGA
CGGCTGCGATTTTATTTATGACTGAAATCATGTCTAATACGGCTGTCGCCAATATGGTGATTCCGATGACGATCGGCCTT
GGCGCCGCGCTTCAGGTCGAGCCGTACGGGCTGATGGCGGCAGCTGCGCTTGCTTCATCGTGCGCCTTCATGCTTCCGAT
CTCCACCCCGCCGAATGCGGCCGTCTTCAGCTCCAATCTGCTGACGATAAAGGATATGGTCAGGGCGGGCTTTTGGCTCA
ATATCGCAGGTGTCTTCTTGATTGTGATCAGCGCATATTTTTGGCTTCCGGCCGTCTTTCAATAA

Upstream 100 bases:

>100_bases
TTCATTTATTAAAATTTTATTTTAAATTTTTTAGAGGAATTTTCCCCGGTCAAAGCGAAAAGTGATGAATGGGAAACCGC
TTTCAAGGGGGATGGGATAG

Downstream 100 bases:

>100_bases
TGTCCGCGAAAAAGCTCTCACTAGTTTTCTTGCATCATCTGCATTAAAATAAAGTTATGACATTACGTTAGGATTGGTAG
ACAGATGAGCATTTTTAAAG

Product: hypothetical protein

Products: NA

Alternate protein names: Na(+)/dicarboxylate symporter [H]

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MRVYTTTKLTGLLLGPISFLLILGLIPEAELAYAPRIVLAVTAWTAVWWITEAVPIPAASLLPVILLPTLGGLDMETTAK
AYGDPIVFMYMGGFIIAIAIEKWNLHKRMALHILKRIGAESHRIVLGVMAATAFLSMWISNAATALMMLPVALAVIKEVQ
EKEILKGESLQKFSKSILLAVAYAASIGGLATLVGSVPNAVFAAMSKQMLNHEIMFFEWFLFGFPVSILFLAILYVYLTK
IKFKVSAFQGKKPDFIDHDLKALGAMTREEKSVFTVFLLTACLWMFKFILPFQISDTSIAIFGAVLLFLIPSTKDERILE
WKDMQSLPWGLLLLFGGGLSLAAGFSATNLTAWIGGKLKLLEGHPYLFVLIILTAAILFMTEIMSNTAVANMVIPMTIGL
GAALQVEPYGLMAAAALASSCAFMLPISTPPNAAVFSSNLLTIKDMVRAGFWLNIAGVFLIVISAYFWLPAVFQ

Sequences:

>Translated_474_residues
MRVYTTTKLTGLLLGPISFLLILGLIPEAELAYAPRIVLAVTAWTAVWWITEAVPIPAASLLPVILLPTLGGLDMETTAK
AYGDPIVFMYMGGFIIAIAIEKWNLHKRMALHILKRIGAESHRIVLGVMAATAFLSMWISNAATALMMLPVALAVIKEVQ
EKEILKGESLQKFSKSILLAVAYAASIGGLATLVGSVPNAVFAAMSKQMLNHEIMFFEWFLFGFPVSILFLAILYVYLTK
IKFKVSAFQGKKPDFIDHDLKALGAMTREEKSVFTVFLLTACLWMFKFILPFQISDTSIAIFGAVLLFLIPSTKDERILE
WKDMQSLPWGLLLLFGGGLSLAAGFSATNLTAWIGGKLKLLEGHPYLFVLIILTAAILFMTEIMSNTAVANMVIPMTIGL
GAALQVEPYGLMAAAALASSCAFMLPISTPPNAAVFSSNLLTIKDMVRAGFWLNIAGVFLIVISAYFWLPAVFQ
>Mature_474_residues
MRVYTTTKLTGLLLGPISFLLILGLIPEAELAYAPRIVLAVTAWTAVWWITEAVPIPAASLLPVILLPTLGGLDMETTAK
AYGDPIVFMYMGGFIIAIAIEKWNLHKRMALHILKRIGAESHRIVLGVMAATAFLSMWISNAATALMMLPVALAVIKEVQ
EKEILKGESLQKFSKSILLAVAYAASIGGLATLVGSVPNAVFAAMSKQMLNHEIMFFEWFLFGFPVSILFLAILYVYLTK
IKFKVSAFQGKKPDFIDHDLKALGAMTREEKSVFTVFLLTACLWMFKFILPFQISDTSIAIFGAVLLFLIPSTKDERILE
WKDMQSLPWGLLLLFGGGLSLAAGFSATNLTAWIGGKLKLLEGHPYLFVLIILTAAILFMTEIMSNTAVANMVIPMTIGL
GAALQVEPYGLMAAAALASSCAFMLPISTPPNAAVFSSNLLTIKDMVRAGFWLNIAGVFLIVISAYFWLPAVFQ

Specific function: Mediates the transport of dicarboxylates across the cytoplasmic membrane via a Na(+)-electrochemical gradient [H]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family. NADC subfamily [H]

Homologues:

Organism=Homo sapiens, GI31377715, Length=570, Percent_Identity=31.9298245614035, Blast_Score=256, Evalue=3e-68,
Organism=Homo sapiens, GI58761541, Length=526, Percent_Identity=32.6996197718631, Blast_Score=251, Evalue=1e-66,
Organism=Homo sapiens, GI29171306, Length=509, Percent_Identity=32.8094302554028, Blast_Score=246, Evalue=4e-65,
Organism=Homo sapiens, GI301069349, Length=504, Percent_Identity=31.7460317460317, Blast_Score=245, Evalue=6e-65,
Organism=Homo sapiens, GI4506979, Length=531, Percent_Identity=34.0866290018832, Blast_Score=240, Evalue=3e-63,
Organism=Homo sapiens, GI301069346, Length=521, Percent_Identity=32.2456813819578, Blast_Score=233, Evalue=4e-61,
Organism=Homo sapiens, GI225637549, Length=580, Percent_Identity=32.0689655172414, Blast_Score=221, Evalue=8e-58,
Organism=Homo sapiens, GI301069353, Length=476, Percent_Identity=32.3529411764706, Blast_Score=217, Evalue=2e-56,
Organism=Homo sapiens, GI225637552, Length=470, Percent_Identity=33.8297872340426, Blast_Score=213, Evalue=4e-55,
Organism=Homo sapiens, GI219802232, Length=431, Percent_Identity=32.0185614849188, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI19923838, Length=552, Percent_Identity=26.6304347826087, Blast_Score=189, Evalue=5e-48,
Organism=Homo sapiens, GI31795546, Length=353, Percent_Identity=28.0453257790368, Blast_Score=145, Evalue=1e-34,
Organism=Escherichia coli, GI1789444, Length=406, Percent_Identity=22.1674876847291, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1786829, Length=383, Percent_Identity=20.3655352480418, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71988385, Length=485, Percent_Identity=32.3711340206186, Blast_Score=223, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI71989118, Length=498, Percent_Identity=29.9196787148594, Blast_Score=222, Evalue=3e-58,
Organism=Caenorhabditis elegans, GI32565804, Length=462, Percent_Identity=32.2510822510823, Blast_Score=213, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI32564681, Length=524, Percent_Identity=28.2442748091603, Blast_Score=189, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI17551790, Length=502, Percent_Identity=25.8964143426295, Blast_Score=173, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6324340, Length=442, Percent_Identity=24.4343891402715, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6322263, Length=455, Percent_Identity=25.0549450549451, Blast_Score=81, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6319885, Length=446, Percent_Identity=24.4394618834081, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI281366409, Length=470, Percent_Identity=29.5744680851064, Blast_Score=201, Evalue=7e-52,
Organism=Drosophila melanogaster, GI17737623, Length=470, Percent_Identity=29.5744680851064, Blast_Score=201, Evalue=7e-52,
Organism=Drosophila melanogaster, GI24666468, Length=470, Percent_Identity=29.5744680851064, Blast_Score=201, Evalue=7e-52,
Organism=Drosophila melanogaster, GI45551633, Length=470, Percent_Identity=29.5744680851064, Blast_Score=201, Evalue=7e-52,
Organism=Drosophila melanogaster, GI281362116, Length=492, Percent_Identity=28.8617886178862, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI281362114, Length=492, Percent_Identity=28.6585365853659, Blast_Score=170, Evalue=2e-42,
Organism=Drosophila melanogaster, GI281362112, Length=492, Percent_Identity=28.6585365853659, Blast_Score=170, Evalue=2e-42,
Organism=Drosophila melanogaster, GI78706796, Length=482, Percent_Identity=26.9709543568465, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI78706798, Length=482, Percent_Identity=26.9709543568465, Blast_Score=130, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 51715; Mature: 51715

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVYTTTKLTGLLLGPISFLLILGLIPEAELAYAPRIVLAVTAWTAVWWITEAVPIPAAS
CEEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHH
LLPVILLPTLGGLDMETTAKAYGDPIVFMYMGGFIIAIAIEKWNLHKRMALHILKRIGAE
HHHHHHHHCCCCCCCHHHHHHHCCCEEEEECCCEEEEEEEECCCHHHHHHHHHHHHHCCC
SHRIVLGVMAATAFLSMWISNAATALMMLPVALAVIKEVQEKEILKGESLQKFSKSILLA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
VAYAASIGGLATLVGSVPNAVFAAMSKQMLNHEIMFFEWFLFGFPVSILFLAILYVYLTK
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
IKFKVSAFQGKKPDFIDHDLKALGAMTREEKSVFTVFLLTACLWMFKFILPFQISDTSIA
HHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCHHH
IFGAVLLFLIPSTKDERILEWKDMQSLPWGLLLLFGGGLSLAAGFSATNLTAWIGGKLKL
HHHHHHHHHCCCCCCCCHHHHHCCCCCCHHHHHHHCCCHHHHCCCCCCCEEEEECCEEEE
LEGHPYLFVLIILTAAILFMTEIMSNTAVANMVIPMTIGLGAALQVEPYGLMAAAALASS
EECCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHCC
CAFMLPISTPPNAAVFSSNLLTIKDMVRAGFWLNIAGVFLIVISAYFWLPAVFQ
CEEEEEECCCCCCHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRVYTTTKLTGLLLGPISFLLILGLIPEAELAYAPRIVLAVTAWTAVWWITEAVPIPAAS
CEEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHH
LLPVILLPTLGGLDMETTAKAYGDPIVFMYMGGFIIAIAIEKWNLHKRMALHILKRIGAE
HHHHHHHHCCCCCCCHHHHHHHCCCEEEEECCCEEEEEEEECCCHHHHHHHHHHHHHCCC
SHRIVLGVMAATAFLSMWISNAATALMMLPVALAVIKEVQEKEILKGESLQKFSKSILLA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
VAYAASIGGLATLVGSVPNAVFAAMSKQMLNHEIMFFEWFLFGFPVSILFLAILYVYLTK
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
IKFKVSAFQGKKPDFIDHDLKALGAMTREEKSVFTVFLLTACLWMFKFILPFQISDTSIA
HHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCHHH
IFGAVLLFLIPSTKDERILEWKDMQSLPWGLLLLFGGGLSLAAGFSATNLTAWIGGKLKL
HHHHHHHHHCCCCCCCCHHHHHCCCCCCHHHHHHHCCCHHHHCCCCCCCEEEEECCEEEE
LEGHPYLFVLIILTAAILFMTEIMSNTAVANMVIPMTIGLGAALQVEPYGLMAAAALASS
EECCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHCC
CAFMLPISTPPNAAVFSSNLLTIKDMVRAGFWLNIAGVFLIVISAYFWLPAVFQ
CEEEEEECCCCCCHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA