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The map label for this gene is bglH [H]

Identifier: 52784548

GI number: 52784548

Start: 759482

End: 760951

Strand: Direct

Name: bglH [H]

Synonym: BLi00749

Alternate gene names: 52784548

Gene position: 759482-760951 (Clockwise)

Preceding gene: 52784547

Following gene: 52784549

Centisome position: 17.99

GC content: 41.77

Gene sequence:

>1470_bases
ATGATGACAAAAACAAAAGGATTTCCAAAAGATTTTTTATGGGGCGGTGCGATTGCCGCAAACCAAGCAGAAGGAGCCTG
GAATGTTGATGGAAAAGGACCGTCTGTTGCTGATATTGCCATGTACCGTTCGAATTTGAGTGTTGAAGATTACGAAGGAC
ATCTTGCTGTTTCTTCTGAAAACATTGAACGCGCAATGAAAGACCCGGACGTAAAAAAATATCCGAAGCGCAGAGGGATT
GACTTTTATCATCACTATAAAGAAGATGTGGCTCTCTTTGCAGAAATGGGTTTTAAAACATTGCGTATATCGATTGCATG
GAGCCGAATTTTCCCGACAGGAGAAGAAGCAGAGCCTAGCGAGAAAGGCCTTCAGTTTTATGATCGTCTGTTTCAAGAAA
TGAAAAAACATAACATTGAACCGATCGTGACTCTGTCACATTATGAAATGCCATTAGCACTTAGTCTGAAATACAACGGA
TGGGTTGAAAGAAAAGTGATCGACCTCTTTGTGAAATTTGCCAATGTGTGTTTTGAACGCTATAAAGATGTCGTAAAATA
CTGGCTTACCTTTAATGAAATTGACAGTATACATCGCCATTCTTTCATTACAGCGGGAATCATTCCTGATCGCTGTCCTG
AAGGGAAAGTAGAAGAAACGGTTTATCAAGCATTGCACCATCAATTTGTGGCATCCGCTCTTGTGACTGCAGATTGTCAT
CGCATCATTCCCGGCAGTCAGGTGGGATGTATGCTAACGAAACTCACGACATACCCGCACACTTGCCATCCGAGTGATGT
TGAACGCGCACTGAAGCAAAACCTTGATAACTATTTCTATGCAGATGTTCAAGTGTTTGGCGAATATCCGCCATTGATCA
AACGCATGCTGGAACGAAAAAATATCAATATTAAGATGGAAGCGGACGATCTTGCCATTATAAAAGAACATACGGTAGAC
TTCGTTTCGTTTAGCTACTATATGTCCCTGACAGAATCTGCACAGGAGGGTCTGGAAAAAACAGATGGCAATACGATTCG
CGGTGTGAAAAATCCATATTTGCCGTCAACAGATTGGGGTTGGCAAATCGATCCGGTCGGCTTAAAGATTTCGCTCATTG
AATTGTATGATCGCTATCAAAAACCTCTCATTATTGTGGAGAACGGCATGGGTGCGAAAGATGTTGTCGAAAGCGATGGA
TCGATCCATGATGACTATCGTATTAGCTATTTCAGAGAGCATTTCCGTCAGATGAAAGAAGCCATTGAAGAAGGTGTTGA
TCTCTTTGGATATACCAGCTGGGGACCCATTGACATTATTAGTGCGGGAACATCTCAAATGTCCAAACGATATGGATTTA
TCCATGTTGATCAAGATGACGATGGCAACGGGACATTGAAGCGCTCACGTAAAGATTCATTCTACTGGTATAAGAAAGTG
ATTGAGACAAACGGAGAAGTATTAGACTAA

Upstream 100 bases:

>100_bases
TTATTACGAATACGGATCAATATGATATAAAAGTCACGCAATTAAAAGAGGTTAATCGTCAAGATACATTGATGGTTGTT
ACACAATTAGGAGGGTAATC

Downstream 100 bases:

>100_bases
AAAACCGCATTCATGAAAAGGTGATGGCGATGTTTAAAATAAAAAAAGTTTTAAACTCGAGTGTGGTACTGGCTGTAGAT
CAGAACCGACAGGAGATGGT

Product: hypothetical protein

Products: NA

Alternate protein names: 6-phospho-beta-glucosidase [H]

Number of amino acids: Translated: 489; Mature: 489

Protein sequence:

>489_residues
MMTKTKGFPKDFLWGGAIAANQAEGAWNVDGKGPSVADIAMYRSNLSVEDYEGHLAVSSENIERAMKDPDVKKYPKRRGI
DFYHHYKEDVALFAEMGFKTLRISIAWSRIFPTGEEAEPSEKGLQFYDRLFQEMKKHNIEPIVTLSHYEMPLALSLKYNG
WVERKVIDLFVKFANVCFERYKDVVKYWLTFNEIDSIHRHSFITAGIIPDRCPEGKVEETVYQALHHQFVASALVTADCH
RIIPGSQVGCMLTKLTTYPHTCHPSDVERALKQNLDNYFYADVQVFGEYPPLIKRMLERKNINIKMEADDLAIIKEHTVD
FVSFSYYMSLTESAQEGLEKTDGNTIRGVKNPYLPSTDWGWQIDPVGLKISLIELYDRYQKPLIIVENGMGAKDVVESDG
SIHDDYRISYFREHFRQMKEAIEEGVDLFGYTSWGPIDIISAGTSQMSKRYGFIHVDQDDDGNGTLKRSRKDSFYWYKKV
IETNGEVLD

Sequences:

>Translated_489_residues
MMTKTKGFPKDFLWGGAIAANQAEGAWNVDGKGPSVADIAMYRSNLSVEDYEGHLAVSSENIERAMKDPDVKKYPKRRGI
DFYHHYKEDVALFAEMGFKTLRISIAWSRIFPTGEEAEPSEKGLQFYDRLFQEMKKHNIEPIVTLSHYEMPLALSLKYNG
WVERKVIDLFVKFANVCFERYKDVVKYWLTFNEIDSIHRHSFITAGIIPDRCPEGKVEETVYQALHHQFVASALVTADCH
RIIPGSQVGCMLTKLTTYPHTCHPSDVERALKQNLDNYFYADVQVFGEYPPLIKRMLERKNINIKMEADDLAIIKEHTVD
FVSFSYYMSLTESAQEGLEKTDGNTIRGVKNPYLPSTDWGWQIDPVGLKISLIELYDRYQKPLIIVENGMGAKDVVESDG
SIHDDYRISYFREHFRQMKEAIEEGVDLFGYTSWGPIDIISAGTSQMSKRYGFIHVDQDDDGNGTLKRSRKDSFYWYKKV
IETNGEVLD
>Mature_489_residues
MMTKTKGFPKDFLWGGAIAANQAEGAWNVDGKGPSVADIAMYRSNLSVEDYEGHLAVSSENIERAMKDPDVKKYPKRRGI
DFYHHYKEDVALFAEMGFKTLRISIAWSRIFPTGEEAEPSEKGLQFYDRLFQEMKKHNIEPIVTLSHYEMPLALSLKYNG
WVERKVIDLFVKFANVCFERYKDVVKYWLTFNEIDSIHRHSFITAGIIPDRCPEGKVEETVYQALHHQFVASALVTADCH
RIIPGSQVGCMLTKLTTYPHTCHPSDVERALKQNLDNYFYADVQVFGEYPPLIKRMLERKNINIKMEADDLAIIKEHTVD
FVSFSYYMSLTESAQEGLEKTDGNTIRGVKNPYLPSTDWGWQIDPVGLKISLIELYDRYQKPLIIVENGMGAKDVVESDG
SIHDDYRISYFREHFRQMKEAIEEGVDLFGYTSWGPIDIISAGTSQMSKRYGFIHVDQDDDGNGTLKRSRKDSFYWYKKV
IETNGEVLD

Specific function: Catalyzes the hydrolysis of aryl-phospho-beta-D- glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Plays a major role in the utilization of arbutin or salicin as the sole carbon source. Bgl

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI110681710, Length=501, Percent_Identity=28.7425149700599, Blast_Score=179, Evalue=5e-45,
Organism=Homo sapiens, GI32481206, Length=497, Percent_Identity=27.7665995975855, Blast_Score=169, Evalue=7e-42,
Organism=Homo sapiens, GI13273313, Length=500, Percent_Identity=27.2, Blast_Score=167, Evalue=3e-41,
Organism=Homo sapiens, GI28376633, Length=493, Percent_Identity=27.3833671399594, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI24497614, Length=494, Percent_Identity=25.9109311740891, Blast_Score=127, Evalue=2e-29,
Organism=Escherichia coli, GI2367174, Length=498, Percent_Identity=51.4056224899598, Blast_Score=510, Evalue=1e-146,
Organism=Escherichia coli, GI2367270, Length=484, Percent_Identity=52.2727272727273, Blast_Score=500, Evalue=1e-143,
Organism=Escherichia coli, GI1789070, Length=484, Percent_Identity=49.5867768595041, Blast_Score=493, Evalue=1e-140,
Organism=Caenorhabditis elegans, GI17552856, Length=503, Percent_Identity=30.6163021868787, Blast_Score=176, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI17539390, Length=500, Percent_Identity=28.8, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI21356577, Length=482, Percent_Identity=25.9336099585062, Blast_Score=152, Evalue=6e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 56248; Mature: 56248

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1 ; PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTKTKGFPKDFLWGGAIAANQAEGAWNVDGKGPSVADIAMYRSNLSVEDYEGHLAVSSE
CCCCCCCCCHHHHCCCCEECCCCCCCEECCCCCCCHHHHHHHHCCCCCCCCCCEEEECHH
NIERAMKDPDVKKYPKRRGIDFYHHYKEDVALFAEMGFKTLRISIAWSRIFPTGEEAEPS
HHHHHHCCCCHHHCHHHCCCHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCCCCCCH
EKGLQFYDRLFQEMKKHNIEPIVTLSHYEMPLALSLKYNGWVERKVIDLFVKFANVCFER
HHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHH
YKDVVKYWLTFNEIDSIHRHSFITAGIIPDRCPEGKVEETVYQALHHQFVASALVTADCH
HHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RIIPGSQVGCMLTKLTTYPHTCHPSDVERALKQNLDNYFYADVQVFGEYPPLIKRMLERK
HCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHC
NINIKMEADDLAIIKEHTVDFVSFSYYMSLTESAQEGLEKTDGNTIRGVKNPYLPSTDWG
CCEEEEECCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCC
WQIDPVGLKISLIELYDRYQKPLIIVENGMGAKDVVESDGSIHDDYRISYFREHFRQMKE
EEECCCCEEEHHHHHHHHHCCCEEEEECCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
AIEEGVDLFGYTSWGPIDIISAGTSQMSKRYGFIHVDQDDDGNGTLKRSRKDSFYWYKKV
HHHCCCCEEECCCCCCEEEEECCHHHHHHCCCEEEECCCCCCCCCCCCCCCCHHHHHHHH
IETNGEVLD
HHCCCCCCC
>Mature Secondary Structure
MMTKTKGFPKDFLWGGAIAANQAEGAWNVDGKGPSVADIAMYRSNLSVEDYEGHLAVSSE
CCCCCCCCCHHHHCCCCEECCCCCCCEECCCCCCCHHHHHHHHCCCCCCCCCCEEEECHH
NIERAMKDPDVKKYPKRRGIDFYHHYKEDVALFAEMGFKTLRISIAWSRIFPTGEEAEPS
HHHHHHCCCCHHHCHHHCCCHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCCCCCCH
EKGLQFYDRLFQEMKKHNIEPIVTLSHYEMPLALSLKYNGWVERKVIDLFVKFANVCFER
HHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHH
YKDVVKYWLTFNEIDSIHRHSFITAGIIPDRCPEGKVEETVYQALHHQFVASALVTADCH
HHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RIIPGSQVGCMLTKLTTYPHTCHPSDVERALKQNLDNYFYADVQVFGEYPPLIKRMLERK
HCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHC
NINIKMEADDLAIIKEHTVDFVSFSYYMSLTESAQEGLEKTDGNTIRGVKNPYLPSTDWG
CCEEEEECCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCC
WQIDPVGLKISLIELYDRYQKPLIIVENGMGAKDVVESDGSIHDDYRISYFREHFRQMKE
EEECCCCEEEHHHHHHHHHCCCEEEEECCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
AIEEGVDLFGYTSWGPIDIISAGTSQMSKRYGFIHVDQDDDGNGTLKRSRKDSFYWYKKV
HHHCCCCEEECCCCCCEEEEECCHHHHHHCCCEEEECCCCCCCCCCCCCCCCHHHHHHHH
IETNGEVLD
HHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7883710; 7704263; 9384377 [H]