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The map label for this gene is gabT [H]

Identifier: 52784294

GI number: 52784294

Start: 476312

End: 477625

Strand: Direct

Name: gabT [H]

Synonym: BLi00474

Alternate gene names: 52784294

Gene position: 476312-477625 (Clockwise)

Preceding gene: 52784292

Following gene: 52784295

Centisome position: 11.28

GC content: 51.98

Gene sequence:

>1314_bases
ATGAGTCGGAACACAAAAGCATTCACAACGGAAGATTGGCAGGCCAAACGGGATCAATTCGTGGCAAGGGGTGTCTCCAA
CGGAAATCGTCATCTGGCCGCTAAAGGGGAAGGTGCCGTTTTATATGATATTGACGGACGCCGTTTTATCGATTTTGCCG
GGGCGATCGGCACATTAAATGTCGGGCATTCACATCCGAAAGTTGTAGAAGCTGTCAAGCGGCAGGCCGAACAGCTCATC
CATCCCGGTTTTAACGTCATGATGTATCCGGCCTATTTGGAATTGGCGGAAAAGCTTTGCCGGCTTGCGCCGGGCGCCCA
TGAGAAAAAAGCGATTTTCCTGAACTCGGGTGCGGAAGCCGTAGAAAACGCCGTGAAAATCGCCAGAAAATATACGAAGC
GTCAAGCCGTCGTTTCTTTTACCCGCGGATTCCACGGACGCACAAACATGACGATGAGCATGACGAGCAAGGTGAAACCG
TACAAATTCGGATTCGGTCCTTTTGCACCCGAGGTATATCAGGCGCCGTTTCCTTACTACTATAGAAAGCCTGAAGGGAT
GACTGATGAAAGCTATGATGACATGGTTATTCAGGCGTTTGACGATTTCTTCGTCTCGTCTGTTGCTCCGGAGACGGTTG
CTTGCGTCGTCATGGAGCCGGTACAGGGAGAAGGCGGTTTTATCATTCCTTCAAAACGGTTTGTGCAGCATGTCGCAGCC
TTCTGCCAAAAACACGGCATCGTTTTTGTCGCTGATGAGATTCAAACAGGCTTTGCCAGAACGGGCAAATATTTTGCGAT
TGAGCATTTTGATGTCGTTCCTGATCTTGTGACAGTGTCAAAATCGCTGGCTGCCGGCGTTCCGCTCAGCGGCGTCATCG
GCCGGGCGGAAATGCTCGATGCGGCGGATCCGGGTGAACTCGGGGGCACCTACGCCGGAAGTCCGCTTGGATGCGTAGCC
GCTTTGGCAGTGCTCGATATTATCGAATCGGAACAGCTCAACAAGCGCTCTGAAGAAATCGGCAAAGCCATCGAAGAGCG
GGCGCTTGAATGGAAGATGAAATATCCGCAGATTGGGGAAGTCCGCCGACTTGGCGCAATGGCTGCGATTGAAATTGTCC
GGGACGAAAAGACGCGGGAGCCGGACAAAGCAGCTGCGGCCAAGATTGCCAAGTACGCCAATGAACACGGTCTGCTCTTG
TTGACGGCAGGGATCAACGGCAACATTATCCGTTTTCTGTCTCCGCTCGTCATTACTGATGAATTACTTGAGGAAGGGTT
CGGCATCATTGAAGAAGCGCTGGAACAGCTCTAG

Upstream 100 bases:

>100_bases
CGCCTCCCTCTGGTACCATCAAAAATTAATGATTGGTACTTTTCATCATACCAAAAAATATTCAGAATTATAAGAAATAA
AAGTGGGGGAGAGATTTTTT

Downstream 100 bases:

>100_bases
TTTGACATCTTCTAAAAGAAGGAGCGGATTTTGATGGGTAAACAGCAAATGAAAAAAACGATGTCGCAGACGGATGTGCT
ATTTTTAGCGATCGGAGCTA

Product: 4-aminobutyrate aminotransferase

Products: NA

Alternate protein names: (S)-3-amino-2-methylpropionate transaminase; GABA aminotransferase; GABA-AT; Gamma-amino-N-butyrate transaminase; GABA transaminase; Glutamate:succinic semialdehyde transaminase; L-AIBAT [H]

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MSRNTKAFTTEDWQAKRDQFVARGVSNGNRHLAAKGEGAVLYDIDGRRFIDFAGAIGTLNVGHSHPKVVEAVKRQAEQLI
HPGFNVMMYPAYLELAEKLCRLAPGAHEKKAIFLNSGAEAVENAVKIARKYTKRQAVVSFTRGFHGRTNMTMSMTSKVKP
YKFGFGPFAPEVYQAPFPYYYRKPEGMTDESYDDMVIQAFDDFFVSSVAPETVACVVMEPVQGEGGFIIPSKRFVQHVAA
FCQKHGIVFVADEIQTGFARTGKYFAIEHFDVVPDLVTVSKSLAAGVPLSGVIGRAEMLDAADPGELGGTYAGSPLGCVA
ALAVLDIIESEQLNKRSEEIGKAIEERALEWKMKYPQIGEVRRLGAMAAIEIVRDEKTREPDKAAAAKIAKYANEHGLLL
LTAGINGNIIRFLSPLVITDELLEEGFGIIEEALEQL

Sequences:

>Translated_437_residues
MSRNTKAFTTEDWQAKRDQFVARGVSNGNRHLAAKGEGAVLYDIDGRRFIDFAGAIGTLNVGHSHPKVVEAVKRQAEQLI
HPGFNVMMYPAYLELAEKLCRLAPGAHEKKAIFLNSGAEAVENAVKIARKYTKRQAVVSFTRGFHGRTNMTMSMTSKVKP
YKFGFGPFAPEVYQAPFPYYYRKPEGMTDESYDDMVIQAFDDFFVSSVAPETVACVVMEPVQGEGGFIIPSKRFVQHVAA
FCQKHGIVFVADEIQTGFARTGKYFAIEHFDVVPDLVTVSKSLAAGVPLSGVIGRAEMLDAADPGELGGTYAGSPLGCVA
ALAVLDIIESEQLNKRSEEIGKAIEERALEWKMKYPQIGEVRRLGAMAAIEIVRDEKTREPDKAAAAKIAKYANEHGLLL
LTAGINGNIIRFLSPLVITDELLEEGFGIIEEALEQL
>Mature_436_residues
SRNTKAFTTEDWQAKRDQFVARGVSNGNRHLAAKGEGAVLYDIDGRRFIDFAGAIGTLNVGHSHPKVVEAVKRQAEQLIH
PGFNVMMYPAYLELAEKLCRLAPGAHEKKAIFLNSGAEAVENAVKIARKYTKRQAVVSFTRGFHGRTNMTMSMTSKVKPY
KFGFGPFAPEVYQAPFPYYYRKPEGMTDESYDDMVIQAFDDFFVSSVAPETVACVVMEPVQGEGGFIIPSKRFVQHVAAF
CQKHGIVFVADEIQTGFARTGKYFAIEHFDVVPDLVTVSKSLAAGVPLSGVIGRAEMLDAADPGELGGTYAGSPLGCVAA
LAVLDIIESEQLNKRSEEIGKAIEERALEWKMKYPQIGEVRRLGAMAAIEIVRDEKTREPDKAAAAKIAKYANEHGLLLL
TAGINGNIIRFLSPLVITDELLEEGFGIIEEALEQL

Specific function: Unknown

COG id: COG0160

COG function: function code E; 4-aminobutyrate aminotransferase and related aminotransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=413, Percent_Identity=32.9297820823245, Blast_Score=206, Evalue=3e-53,
Organism=Homo sapiens, GI37574042, Length=414, Percent_Identity=31.4009661835749, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI24119277, Length=402, Percent_Identity=33.5820895522388, Blast_Score=185, Evalue=6e-47,
Organism=Homo sapiens, GI13994255, Length=426, Percent_Identity=31.2206572769953, Blast_Score=182, Evalue=5e-46,
Organism=Homo sapiens, GI226442709, Length=394, Percent_Identity=31.9796954314721, Blast_Score=179, Evalue=4e-45,
Organism=Homo sapiens, GI226442705, Length=414, Percent_Identity=30.9178743961353, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI284507298, Length=332, Percent_Identity=33.433734939759, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI188536080, Length=423, Percent_Identity=26.4775413711584, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI38679950, Length=423, Percent_Identity=26.4775413711584, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI38679946, Length=423, Percent_Identity=26.4775413711584, Blast_Score=125, Evalue=6e-29,
Organism=Escherichia coli, GI1787560, Length=428, Percent_Identity=45.7943925233645, Blast_Score=369, Evalue=1e-103,
Organism=Escherichia coli, GI1789016, Length=428, Percent_Identity=43.2242990654206, Blast_Score=368, Evalue=1e-103,
Organism=Escherichia coli, GI1789759, Length=401, Percent_Identity=31.6708229426434, Blast_Score=203, Evalue=1e-53,
Organism=Escherichia coli, GI1788044, Length=409, Percent_Identity=30.8068459657702, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI145693181, Length=399, Percent_Identity=32.3308270676692, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI1786991, Length=414, Percent_Identity=29.4685990338164, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1786349, Length=322, Percent_Identity=29.5031055900621, Blast_Score=137, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI71992977, Length=426, Percent_Identity=31.6901408450704, Blast_Score=205, Evalue=4e-53,
Organism=Caenorhabditis elegans, GI32564660, Length=428, Percent_Identity=32.0093457943925, Blast_Score=200, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI25144271, Length=409, Percent_Identity=31.5403422982885, Blast_Score=191, Evalue=9e-49,
Organism=Caenorhabditis elegans, GI25144274, Length=300, Percent_Identity=31.3333333333333, Blast_Score=136, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17541228, Length=439, Percent_Identity=24.8291571753986, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI71981843, Length=155, Percent_Identity=32.9032258064516, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323470, Length=423, Percent_Identity=31.2056737588652, Blast_Score=198, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6324432, Length=415, Percent_Identity=32.7710843373494, Blast_Score=196, Evalue=5e-51,
Organism=Saccharomyces cerevisiae, GI6321456, Length=359, Percent_Identity=25.0696378830084, Blast_Score=100, Evalue=9e-22,
Organism=Saccharomyces cerevisiae, GI6324386, Length=427, Percent_Identity=24.1217798594848, Blast_Score=91, Evalue=5e-19,
Organism=Drosophila melanogaster, GI161085790, Length=419, Percent_Identity=32.6968973747017, Blast_Score=212, Evalue=4e-55,
Organism=Drosophila melanogaster, GI28574759, Length=403, Percent_Identity=33.2506203473945, Blast_Score=210, Evalue=1e-54,
Organism=Drosophila melanogaster, GI21357415, Length=411, Percent_Identity=31.6301703163017, Blast_Score=194, Evalue=8e-50,
Organism=Drosophila melanogaster, GI21356575, Length=404, Percent_Identity=31.6831683168317, Blast_Score=181, Evalue=1e-45,
Organism=Drosophila melanogaster, GI281366494, Length=380, Percent_Identity=26.0526315789474, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24667139, Length=380, Percent_Identity=26.0526315789474, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24667143, Length=380, Percent_Identity=26.0526315789474, Blast_Score=112, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004632
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.19; =2.6.1.22 [H]

Molecular weight: Translated: 47959; Mature: 47827

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRNTKAFTTEDWQAKRDQFVARGVSNGNRHLAAKGEGAVLYDIDGRRFIDFAGAIGTLN
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEECCCCEEEEHHCCCEECC
VGHSHPKVVEAVKRQAEQLIHPGFNVMMYPAYLELAEKLCRLAPGAHEKKAIFLNSGAEA
CCCCCHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHH
VENAVKIARKYTKRQAVVSFTRGFHGRTNMTMSMTSKVKPYKFGFGPFAPEVYQAPFPYY
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHCCCCCCCCCCCCCCCHHHCCCCCCE
YRKPEGMTDESYDDMVIQAFDDFFVSSVAPETVACVVMEPVQGEGGFIIPSKRFVQHVAA
EECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEECCCHHHHHHHHH
FCQKHGIVFVADEIQTGFARTGKYFAIEHFDVVPDLVTVSKSLAAGVPLSGVIGRAEMLD
HHHHCCEEEEECCHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHCCCCHHHHHCHHHHHC
AADPGELGGTYAGSPLGCVAALAVLDIIESEQLNKRSEEIGKAIEERALEWKMKYPQIGE
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
VRRLGAMAAIEIVRDEKTREPDKAAAAKIAKYANEHGLLLLTAGINGNIIRFLSPLVITD
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHH
ELLEEGFGIIEEALEQL
HHHHCCHHHHHHHHHHC
>Mature Secondary Structure 
SRNTKAFTTEDWQAKRDQFVARGVSNGNRHLAAKGEGAVLYDIDGRRFIDFAGAIGTLN
CCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEECCCCEEEEHHCCCEECC
VGHSHPKVVEAVKRQAEQLIHPGFNVMMYPAYLELAEKLCRLAPGAHEKKAIFLNSGAEA
CCCCCHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHH
VENAVKIARKYTKRQAVVSFTRGFHGRTNMTMSMTSKVKPYKFGFGPFAPEVYQAPFPYY
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHCCCCCCCCCCCCCCCHHHCCCCCCE
YRKPEGMTDESYDDMVIQAFDDFFVSSVAPETVACVVMEPVQGEGGFIIPSKRFVQHVAA
EECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEECCCHHHHHHHHH
FCQKHGIVFVADEIQTGFARTGKYFAIEHFDVVPDLVTVSKSLAAGVPLSGVIGRAEMLD
HHHHCCEEEEECCHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHCCCCHHHHHCHHHHHC
AADPGELGGTYAGSPLGCVAALAVLDIIESEQLNKRSEEIGKAIEERALEWKMKYPQIGE
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
VRRLGAMAAIEIVRDEKTREPDKAAAAKIAKYANEHGLLLLTAGINGNIIRFLSPLVITD
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHH
ELLEEGFGIIEEALEQL
HHHHCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]