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The map label for this gene is ddc [H]

Identifier: 52784236

GI number: 52784236

Start: 413775

End: 415436

Strand: Direct

Name: ddc [H]

Synonym: BLi00416

Alternate gene names: 52784236

Gene position: 413775-415436 (Clockwise)

Preceding gene: 52784235

Following gene: 52784237

Centisome position: 9.8

GC content: 49.52

Gene sequence:

>1662_bases
ATGCAGCAACGCAATACACCGGATGTACAGAGATGGTTTCCGAGCGAGGACGGAAATGAAGCAAAACGAAACGAGTTCCT
ATCATTGATCGAGCAGCTGATCGAGGGAGTGGACAACCTGAAAAATCCGGATCAGGTCAACCTTGGCGGCGAGAAGAACC
GAGAGGGCTTCTTTTATGAAAAGCTGGTTGCAGAGAGTCGGATTCCGCATGAAGGTGCGCCGATGAAAGAGGTTAACGAA
GAGCTGTTGAAGCTGTTGCACGGCCATCCGTATCACACCAAATACTTTTTCACGAACATTCTGCCGATGGCCAGCATCCC
GGGGATATTAGGCATGCTTACGGCGTTTATGGTCAATGGCAACAACCTGTGGGATGTGTACGGTCCAGCCGGAGCGGAGG
CGGAAGTGAAGGTTACAGCGATGATGTCAAAGCTTGCTGGGTATGATGCCGAAACAAGCGGAGGATATACAACGTGGGGA
GGACAAGGGGCGGTATACAGCGGCCTCAGAATCGCGATTGCCAAAATGGCTCCGTCATCCCTAAAAGAAGGGGTTCCCGG
CAATTTCTATGCGTTTTGTTCTGAAGCGGCTCATTACAGCTTGTATAAGTCGATGGAAGCCGCAGGACTCGGCAGCGATC
ATTTAATTAAAGTCAAAACAAATCTCGACCATTCCATGGATACGGAAGATTTGCGAGAGAAGCTTAGACAAGTATGCGAA
GCCGGGGGCATTCCCGTCTATATCGTAGCCACGACGGGAACGACAGATGCGATCGGCATCGATGATGTGAGCGCTGTCCG
CCGTGCGGCTGAAGAAACCGCGAAGAGCTTCGGGCTGCCGGTTCCGCATATCCACGCCGATTCCGCCCTGGGAGGATTTT
TTGCCTTTTTTAATGAGTACGATCTGAATGAGAACGCTTTATCCTTCAGTCCCGGTGTCCTCAGCATGATCAAACCGATT
CAGGAAAAAATGAGGCATCTGCATGCTGCCGATTCGCTTTGCTTTGATTTTCAGAAGCTCGGGCAGACGCCTTATGTGAC
GAGCCTGTTTCTTGTGAAGGATCGCAATGACTTAAAACGGATCGATCTGGATCCCGATGAGACGCCGTATGTCGGCCACC
GCGGCTATGGGGACTACCATACGGGCTACACGCTGGAATGTTCGCGCATGGCCAGTTCGATCAGTATGTACAGCGCATTG
ATGGCATTTGGCTATGAAGGCTATCAAAAGCTGCTTGCCCAGTTCCTTGAAGTCAACCTGCATTTTAGGGAACAGCTGTC
TCGGCAGATTCCGGAGGCCGATATTGTGAACCCGGACAACTGCGGCATGTCTACGCTGTTTCGCATTTATCCTGAAGGGG
CGCCTAGATTTGAAGACGAAATTTCGGGAGCATGCACCATTGAAGAGCTGGAAAGAAACAATGCGCTTACTGAAAAATTA
TTTGAAAAGCTCGGAACAAAAAGGGACAAGATGTTTTTTGGCGATACGAAAAAACACTTGCTTGTGAAGTCCTGTGAAGG
GGTTGAATTACCGCTTTGCGTCAGCAAATTTTTCGTCATTTCTCCGTATACCATGCCTGAACATGTCCCGGGAATTATCG
ATTATTTAAAAGAAACTATTGAGGAAGTCTTCCGGGAGCATGGGTCTCTCATGACAAATTAA

Upstream 100 bases:

>100_bases
GAACTTTTTGAGCGAAGGCCTAAAAATATAGGAATATTATACCGATATGGCAAGTGAAATCTTTTTCTGAAATATAAAAG
ACAAGGCAGGAGAGAAAATC

Downstream 100 bases:

>100_bases
AGGGGATATAGACGATGAAAACGTTGAAGAAAAAGCTAACAGAACACATTTCAGTCAAAATTATGATTGGCGTCGCCTTA
GTGCTTTTAATCACGATCGC

Product: hypothetical protein

Products: NA

Alternate protein names: DABA decarboxylase; DABA-DC [H]

Number of amino acids: Translated: 553; Mature: 553

Protein sequence:

>553_residues
MQQRNTPDVQRWFPSEDGNEAKRNEFLSLIEQLIEGVDNLKNPDQVNLGGEKNREGFFYEKLVAESRIPHEGAPMKEVNE
ELLKLLHGHPYHTKYFFTNILPMASIPGILGMLTAFMVNGNNLWDVYGPAGAEAEVKVTAMMSKLAGYDAETSGGYTTWG
GQGAVYSGLRIAIAKMAPSSLKEGVPGNFYAFCSEAAHYSLYKSMEAAGLGSDHLIKVKTNLDHSMDTEDLREKLRQVCE
AGGIPVYIVATTGTTDAIGIDDVSAVRRAAEETAKSFGLPVPHIHADSALGGFFAFFNEYDLNENALSFSPGVLSMIKPI
QEKMRHLHAADSLCFDFQKLGQTPYVTSLFLVKDRNDLKRIDLDPDETPYVGHRGYGDYHTGYTLECSRMASSISMYSAL
MAFGYEGYQKLLAQFLEVNLHFREQLSRQIPEADIVNPDNCGMSTLFRIYPEGAPRFEDEISGACTIEELERNNALTEKL
FEKLGTKRDKMFFGDTKKHLLVKSCEGVELPLCVSKFFVISPYTMPEHVPGIIDYLKETIEEVFREHGSLMTN

Sequences:

>Translated_553_residues
MQQRNTPDVQRWFPSEDGNEAKRNEFLSLIEQLIEGVDNLKNPDQVNLGGEKNREGFFYEKLVAESRIPHEGAPMKEVNE
ELLKLLHGHPYHTKYFFTNILPMASIPGILGMLTAFMVNGNNLWDVYGPAGAEAEVKVTAMMSKLAGYDAETSGGYTTWG
GQGAVYSGLRIAIAKMAPSSLKEGVPGNFYAFCSEAAHYSLYKSMEAAGLGSDHLIKVKTNLDHSMDTEDLREKLRQVCE
AGGIPVYIVATTGTTDAIGIDDVSAVRRAAEETAKSFGLPVPHIHADSALGGFFAFFNEYDLNENALSFSPGVLSMIKPI
QEKMRHLHAADSLCFDFQKLGQTPYVTSLFLVKDRNDLKRIDLDPDETPYVGHRGYGDYHTGYTLECSRMASSISMYSAL
MAFGYEGYQKLLAQFLEVNLHFREQLSRQIPEADIVNPDNCGMSTLFRIYPEGAPRFEDEISGACTIEELERNNALTEKL
FEKLGTKRDKMFFGDTKKHLLVKSCEGVELPLCVSKFFVISPYTMPEHVPGIIDYLKETIEEVFREHGSLMTN
>Mature_553_residues
MQQRNTPDVQRWFPSEDGNEAKRNEFLSLIEQLIEGVDNLKNPDQVNLGGEKNREGFFYEKLVAESRIPHEGAPMKEVNE
ELLKLLHGHPYHTKYFFTNILPMASIPGILGMLTAFMVNGNNLWDVYGPAGAEAEVKVTAMMSKLAGYDAETSGGYTTWG
GQGAVYSGLRIAIAKMAPSSLKEGVPGNFYAFCSEAAHYSLYKSMEAAGLGSDHLIKVKTNLDHSMDTEDLREKLRQVCE
AGGIPVYIVATTGTTDAIGIDDVSAVRRAAEETAKSFGLPVPHIHADSALGGFFAFFNEYDLNENALSFSPGVLSMIKPI
QEKMRHLHAADSLCFDFQKLGQTPYVTSLFLVKDRNDLKRIDLDPDETPYVGHRGYGDYHTGYTLECSRMASSISMYSAL
MAFGYEGYQKLLAQFLEVNLHFREQLSRQIPEADIVNPDNCGMSTLFRIYPEGAPRFEDEISGACTIEELERNNALTEKL
FEKLGTKRDKMFFGDTKKHLLVKSCEGVELPLCVSKFFVISPYTMPEHVPGIIDYLKETIEEVFREHGSLMTN

Specific function: Unknown

COG id: COG0076

COG function: function code E; Glutamate decarboxylase and related PLP-dependent proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the group II decarboxylase family [H]

Homologues:

Organism=Homo sapiens, GI197276620, Length=281, Percent_Identity=23.8434163701068, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI4503875, Length=281, Percent_Identity=23.8434163701068, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI58331246, Length=341, Percent_Identity=22.8739002932551, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21356415, Length=380, Percent_Identity=26.5789473684211, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI17136594, Length=405, Percent_Identity=23.9506172839506, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24657193, Length=425, Percent_Identity=23.2941176470588, Blast_Score=73, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24657185, Length=425, Percent_Identity=23.2941176470588, Blast_Score=73, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24657188, Length=425, Percent_Identity=23.2941176470588, Blast_Score=73, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002129
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR021115 [H]

Pfam domain/function: PF00282 Pyridoxal_deC [H]

EC number: =4.1.1.86 [H]

Molecular weight: Translated: 61704; Mature: 61704

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS00501 SPASE_I_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQRNTPDVQRWFPSEDGNEAKRNEFLSLIEQLIEGVDNLKNPDQVNLGGEKNREGFFYE
CCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCHHHH
KLVAESRIPHEGAPMKEVNEELLKLLHGHPYHTKYFFTNILPMASIPGILGMLTAFMVNG
HHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NNLWDVYGPAGAEAEVKVTAMMSKLAGYDAETSGGYTTWGGQGAVYSGLRIAIAKMAPSS
CCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEECCCCCCHHHHHHHHHHHHCHHH
LKEGVPGNFYAFCSEAAHYSLYKSMEAAGLGSDHLIKVKTNLDHSMDTEDLREKLRQVCE
HHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHH
AGGIPVYIVATTGTTDAIGIDDVSAVRRAAEETAKSFGLPVPHIHADSALGGFFAFFNEY
CCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHC
DLNENALSFSPGVLSMIKPIQEKMRHLHAADSLCFDFQKLGQTPYVTSLFLVKDRNDLKR
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCEE
IDLDPDETPYVGHRGYGDYHTGYTLECSRMASSISMYSALMAFGYEGYQKLLAQFLEVNL
CCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
HFREQLSRQIPEADIVNPDNCGMSTLFRIYPEGAPRFEDEISGACTIEELERNNALTEKL
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHCCCCEEHHHHHHCCHHHHHH
FEKLGTKRDKMFFGDTKKHLLVKSCEGVELPLCVSKFFVISPYTMPEHVPGIIDYLKETI
HHHHCCCCCCEEECCCHHHHHHHCCCCCCCHHHHHHHHEECCCCCCHHCCHHHHHHHHHH
EEVFREHGSLMTN
HHHHHHCCCCCCC
>Mature Secondary Structure
MQQRNTPDVQRWFPSEDGNEAKRNEFLSLIEQLIEGVDNLKNPDQVNLGGEKNREGFFYE
CCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCHHHH
KLVAESRIPHEGAPMKEVNEELLKLLHGHPYHTKYFFTNILPMASIPGILGMLTAFMVNG
HHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NNLWDVYGPAGAEAEVKVTAMMSKLAGYDAETSGGYTTWGGQGAVYSGLRIAIAKMAPSS
CCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEECCCCCCHHHHHHHHHHHHCHHH
LKEGVPGNFYAFCSEAAHYSLYKSMEAAGLGSDHLIKVKTNLDHSMDTEDLREKLRQVCE
HHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHH
AGGIPVYIVATTGTTDAIGIDDVSAVRRAAEETAKSFGLPVPHIHADSALGGFFAFFNEY
CCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHC
DLNENALSFSPGVLSMIKPIQEKMRHLHAADSLCFDFQKLGQTPYVTSLFLVKDRNDLKR
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCEE
IDLDPDETPYVGHRGYGDYHTGYTLECSRMASSISMYSALMAFGYEGYQKLLAQFLEVNL
CCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
HFREQLSRQIPEADIVNPDNCGMSTLFRIYPEGAPRFEDEISGACTIEELERNNALTEKL
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHCCCCEEHHHHHHCCHHHHHH
FEKLGTKRDKMFFGDTKKHLLVKSCEGVELPLCVSKFFVISPYTMPEHVPGIIDYLKETI
HHHHCCCCCCEEECCCHHHHHHHCCCCCCCHHHHHHHHEECCCCCCHHCCHHHHHHHHHH
EEVFREHGSLMTN
HHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 9514614 [H]