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The map label for this gene is ycxD [H]

Identifier: 52784228

GI number: 52784228

Start: 405955

End: 407304

Strand: Direct

Name: ycxD [H]

Synonym: BLi00406

Alternate gene names: 52784228

Gene position: 405955-407304 (Clockwise)

Preceding gene: 52784226

Following gene: 52784230

Centisome position: 9.61

GC content: 47.33

Gene sequence:

>1350_bases
ATGCACAAATATGTCGCACTGATGAACGAATTGGAGGATATGATCGAAGACAAATCCTTTCAGGAAGGGGACAGGCTGCC
TTCCATCCGCGCGCTGGCCATACGTTTCAAGGTAAGCAAAAGCACGGTCATCAGGGCGTTGAACGAGCTGGAAAGACGGC
ACCTCATCTATTCAGTGCCGAAAAGCGGCTATTACGTCGTGAAAAAAACGAATCAGCGGCCCAACTCCGGAAAGGCTGTA
ATCGATTTCGCAGCATCCGCTCCTGATCCGGATGTTTTTCCATACATCGATTTTCAGCATTGCATCAATAAAGCCATCGA
TACATACAAAAACGATCTGTTTATTTATGGGACGCCGAAAGGTCTGCCGTCGTTAATCCAAGCCGTTCAGAAAGAGCTCG
CAAACAGCCAGGTGTTTGCAAAAGAGGAACACATATTTATTACATCAGGCGTCCAGCAGGCCCTCGCCTTGCTCGCTTCA
ATGCCTTTTCCAAACCGGAAGCGGAAAGTTCTGATCGAACAGCCGAGCTATCATTTATTGATTAAATACCTTGAAGTTCA
CGGCATCCCCGCGGTCGGCATCGAGAGAACCGCCGAAGGCATCGATATGGACGAGCTGGAGCGCATCTTTCAAACCGAAG
ATATCAAATTTTTTTATACGATGCCGAGATTCCACAATCCGCTCGGGACATCCTACACGGAACGGGAAAAAACGGCCATC
GTCAAGCTGGCGGAGAAATATGACGTCTATATTGCCGAGGATGATTTTTTAGGAGATTTGGAGAATGATAAAAAGGCGGA
TCCGTTACATTACTATGACATTTCTTCCCACGTTATTTATTTGAAAAGTTTCTCAAAGATTATTTTTCCGGGTCTGCGGG
TCGGAGCCGCCGTGCTGCCCGATTCTCTGACAATTGTGTTCAACCGGTACAAACAGCTGCTCGACATTGACAGTTCCATG
CTGTCTCAGGCCGCTTTGGAGATCTATTTGAAGAGCGGGATGTTTGAAAAGCATAAGCAAAAGATCCGTTCTTCCTATCA
AAAAAGATCATGCCTTCTGCATGATCTGCTAAAAGAATGTTCCGCGTCTCTAGGGGATGTGTTTGAATTTCATCCTCCCG
CACAGCCGGCTATCCACACCCATATTGAATTGGACCGGACGATCCCGGCATCCCGTCTGATTAAAAGCCTACAAAAACGG
GACGTCCTGCTCGAACCGGTCAACGCTCATTATATGCCGGCTTTTCCAAAAAGAAATCTATTGAAAATCAATACGTCCAA
TGTGAAGGAAGAGGACATCCGCAGCGGCATCGAGCGGTTGCGGCAAGCGGTGGAAACCGCTTATTTTTAG

Upstream 100 bases:

>100_bases
AGATATTTTACCGGCTTCTGTCATCTTATACGGAAGCGAAATCTGATACAATACAAAAAAACGGAATCTGTACCGTTACA
GATTGGCGAAGGAGACGAAC

Downstream 100 bases:

>100_bases
GGCGGGACTTTTTAAAGCATTGACAGTTCAGCGCAGCTTTTCATCACAATCCGGCCGGGAAATTCAGGTGCGGCGGAACA
CACCGCCATTTTATAGCCGG

Product: YcxD

Products: NA

Alternate protein names: ORF8 [H]

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MHKYVALMNELEDMIEDKSFQEGDRLPSIRALAIRFKVSKSTVIRALNELERRHLIYSVPKSGYYVVKKTNQRPNSGKAV
IDFAASAPDPDVFPYIDFQHCINKAIDTYKNDLFIYGTPKGLPSLIQAVQKELANSQVFAKEEHIFITSGVQQALALLAS
MPFPNRKRKVLIEQPSYHLLIKYLEVHGIPAVGIERTAEGIDMDELERIFQTEDIKFFYTMPRFHNPLGTSYTEREKTAI
VKLAEKYDVYIAEDDFLGDLENDKKADPLHYYDISSHVIYLKSFSKIIFPGLRVGAAVLPDSLTIVFNRYKQLLDIDSSM
LSQAALEIYLKSGMFEKHKQKIRSSYQKRSCLLHDLLKECSASLGDVFEFHPPAQPAIHTHIELDRTIPASRLIKSLQKR
DVLLEPVNAHYMPAFPKRNLLKINTSNVKEEDIRSGIERLRQAVETAYF

Sequences:

>Translated_449_residues
MHKYVALMNELEDMIEDKSFQEGDRLPSIRALAIRFKVSKSTVIRALNELERRHLIYSVPKSGYYVVKKTNQRPNSGKAV
IDFAASAPDPDVFPYIDFQHCINKAIDTYKNDLFIYGTPKGLPSLIQAVQKELANSQVFAKEEHIFITSGVQQALALLAS
MPFPNRKRKVLIEQPSYHLLIKYLEVHGIPAVGIERTAEGIDMDELERIFQTEDIKFFYTMPRFHNPLGTSYTEREKTAI
VKLAEKYDVYIAEDDFLGDLENDKKADPLHYYDISSHVIYLKSFSKIIFPGLRVGAAVLPDSLTIVFNRYKQLLDIDSSM
LSQAALEIYLKSGMFEKHKQKIRSSYQKRSCLLHDLLKECSASLGDVFEFHPPAQPAIHTHIELDRTIPASRLIKSLQKR
DVLLEPVNAHYMPAFPKRNLLKINTSNVKEEDIRSGIERLRQAVETAYF
>Mature_449_residues
MHKYVALMNELEDMIEDKSFQEGDRLPSIRALAIRFKVSKSTVIRALNELERRHLIYSVPKSGYYVVKKTNQRPNSGKAV
IDFAASAPDPDVFPYIDFQHCINKAIDTYKNDLFIYGTPKGLPSLIQAVQKELANSQVFAKEEHIFITSGVQQALALLAS
MPFPNRKRKVLIEQPSYHLLIKYLEVHGIPAVGIERTAEGIDMDELERIFQTEDIKFFYTMPRFHNPLGTSYTEREKTAI
VKLAEKYDVYIAEDDFLGDLENDKKADPLHYYDISSHVIYLKSFSKIIFPGLRVGAAVLPDSLTIVFNRYKQLLDIDSSM
LSQAALEIYLKSGMFEKHKQKIRSSYQKRSCLLHDLLKECSASLGDVFEFHPPAQPAIHTHIELDRTIPASRLIKSLQKR
DVLLEPVNAHYMPAFPKRNLLKINTSNVKEEDIRSGIERLRQAVETAYF

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=404, Percent_Identity=26.2376237623762, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI33469970, Length=404, Percent_Identity=26.2376237623762, Blast_Score=92, Evalue=8e-19,
Organism=Escherichia coli, GI1787710, Length=377, Percent_Identity=27.8514588859416, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1790797, Length=478, Percent_Identity=24.4769874476987, Blast_Score=132, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6321236, Length=331, Percent_Identity=24.4712990936556, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21356535, Length=317, Percent_Identity=24.6056782334385, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 51457; Mature: 51457

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKYVALMNELEDMIEDKSFQEGDRLPSIRALAIRFKVSKSTVIRALNELERRHLIYSVP
CCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHEEEECC
KSGYYVVKKTNQRPNSGKAVIDFAASAPDPDVFPYIDFQHCINKAIDTYKNDLFIYGTPK
CCCEEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCC
GLPSLIQAVQKELANSQVFAKEEHIFITSGVQQALALLASMPFPNRKRKVLIEQPSYHLL
CHHHHHHHHHHHHCCCCEEECCCCEEEEHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHH
IKYLEVHGIPAVGIERTAEGIDMDELERIFQTEDIKFFYTMPRFHNPLGTSYTEREKTAI
HHHHHHCCCCCCCHHHHCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHH
VKLAEKYDVYIAEDDFLGDLENDKKADPLHYYDISSHVIYLKSFSKIIFPGLRVGAAVLP
HHHHHHCEEEEECCCCCCCCCCCCCCCCEEEEECCCCEEEEHHHHHHHCCCHHHHHHHCC
DSLTIVFNRYKQLLDIDSSMLSQAALEIYLKSGMFEKHKQKIRSSYQKRSCLLHDLLKEC
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SASLGDVFEFHPPAQPAIHTHIELDRTIPASRLIKSLQKRDVLLEPVNAHYMPAFPKRNL
HHHHCCHHCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCEECCCCCCCCCCCCCCCE
LKINTSNVKEEDIRSGIERLRQAVETAYF
EEEECCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHKYVALMNELEDMIEDKSFQEGDRLPSIRALAIRFKVSKSTVIRALNELERRHLIYSVP
CCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHEEEECC
KSGYYVVKKTNQRPNSGKAVIDFAASAPDPDVFPYIDFQHCINKAIDTYKNDLFIYGTPK
CCCEEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCC
GLPSLIQAVQKELANSQVFAKEEHIFITSGVQQALALLASMPFPNRKRKVLIEQPSYHLL
CHHHHHHHHHHHHCCCCEEECCCCEEEEHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHH
IKYLEVHGIPAVGIERTAEGIDMDELERIFQTEDIKFFYTMPRFHNPLGTSYTEREKTAI
HHHHHHCCCCCCCHHHHCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHH
VKLAEKYDVYIAEDDFLGDLENDKKADPLHYYDISSHVIYLKSFSKIIFPGLRVGAAVLP
HHHHHHCEEEEECCCCCCCCCCCCCCCCEEEEECCCCEEEEHHHHHHHCCCHHHHHHHCC
DSLTIVFNRYKQLLDIDSSMLSQAALEIYLKSGMFEKHKQKIRSSYQKRSCLLHDLLKEC
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SASLGDVFEFHPPAQPAIHTHIELDRTIPASRLIKSLQKRDVLLEPVNAHYMPAFPKRNL
HHHHCCHHCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCEECCCCCCCCCCCCCCCE
LKINTSNVKEEDIRSGIERLRQAVETAYF
EEEECCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8355609; 8969502; 9384377 [H]