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The map label for this gene is ccdA [H]

Identifier: 52784184

GI number: 52784184

Start: 338283

End: 338996

Strand: Direct

Name: ccdA [H]

Synonym: BLi00362

Alternate gene names: 52784184

Gene position: 338283-338996 (Clockwise)

Preceding gene: 52784183

Following gene: 52784186

Centisome position: 8.01

GC content: 45.94

Gene sequence:

>714_bases
ATGTGGAAGTATATGGCCGCTTTATGGCTGGCATTCGGCGGCGGTTTCCTGTCGTTTATTTCTCCTTGCTGCCTGCCTTT
GTATCCATCATTTATTTCCTACATCACCGGGATTTCGGTCGGCGATTTGAAAAACCGGCATGCAAAGCATATCAAACAAT
CGGTGATGATTCACGCAGCGGCTTTTTTGGCCGGTTTTTCTGTGATTTTTTACATATTGGGTTTCTCTGCCAGCTCGGTT
GGTCTGCTGTTTTTGCAATACCATAACTTAATCCGCATGCTGGGCGGGATATTTTTCGTCGTCATGGGACTGTTCTTACT
CGGCGTTTTCCGGCCGGCTTTTATGATGAAGGAGCGGCGCTTTTCGATTAGAAAGGGAAAAATAGGCCTGCTGAATTCAA
TGCTGGTCGGAATGATTTTTGCGGCGGGCTGGACGCCGTGCATCGGGCCTATATTCGGAACGATCGCATACGCAAATTTT
CAGAACCCTGATTTTGGGAGCGCATTCATGATGATCACCGCATATTCTTTAGGCTTTGCCATTCCTTTTTTGCTCATGGC
GTTTTTTATCGGAAACATCAGGCCGCTTATGAAATATTCGAATATGCTCATGAAGATCGGAGGCGCGCTGATGATCGTCA
TCGGCATCCTGCTTTATACGGACAACATGATATGGATTAACATCTGGTATTCGAATTTGACGAATCTCTTTTGA

Upstream 100 bases:

>100_bases
GCGGCTTCAAATATACAAAAAATCACCGCCATGATAGGCGGTTTTTTATGTTATGCTAGAGAAAGAGAATCGCATGGTAA
AAAATATATAAACATGAAAG

Downstream 100 bases:

>100_bases
AAAACTTCCGCATGCTGCATTATGTGAGTAAGATTGTGAAAAACAGCAAAATCGCGTTAAATAAACTATGGATGATCATC
GCAGGTATAATCGATCGTGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MWKYMAALWLAFGGGFLSFISPCCLPLYPSFISYITGISVGDLKNRHAKHIKQSVMIHAAAFLAGFSVIFYILGFSASSV
GLLFLQYHNLIRMLGGIFFVVMGLFLLGVFRPAFMMKERRFSIRKGKIGLLNSMLVGMIFAAGWTPCIGPIFGTIAYANF
QNPDFGSAFMMITAYSLGFAIPFLLMAFFIGNIRPLMKYSNMLMKIGGALMIVIGILLYTDNMIWINIWYSNLTNLF

Sequences:

>Translated_237_residues
MWKYMAALWLAFGGGFLSFISPCCLPLYPSFISYITGISVGDLKNRHAKHIKQSVMIHAAAFLAGFSVIFYILGFSASSV
GLLFLQYHNLIRMLGGIFFVVMGLFLLGVFRPAFMMKERRFSIRKGKIGLLNSMLVGMIFAAGWTPCIGPIFGTIAYANF
QNPDFGSAFMMITAYSLGFAIPFLLMAFFIGNIRPLMKYSNMLMKIGGALMIVIGILLYTDNMIWINIWYSNLTNLF
>Mature_237_residues
MWKYMAALWLAFGGGFLSFISPCCLPLYPSFISYITGISVGDLKNRHAKHIKQSVMIHAAAFLAGFSVIFYILGFSASSV
GLLFLQYHNLIRMLGGIFFVVMGLFLLGVFRPAFMMKERRFSIRKGKIGLLNSMLVGMIFAAGWTPCIGPIFGTIAYANF
QNPDFGSAFMMITAYSLGFAIPFLLMAFFIGNIRPLMKYSNMLMKIGGALMIVIGILLYTDNMIWINIWYSNLTNLF

Specific function: Cytochrome c oxidase activity is partially restored by mutations in bdbC or bdbD that are defective in the synthesis of disulfide bond containing proteins. The same mutations abrogate the need for CcdA in sporulation [H]

COG id: COG0785

COG function: function code O; Cytochrome c biogenesis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834 [H]

Pfam domain/function: PF02683 DsbD [H]

EC number: NA

Molecular weight: Translated: 26533; Mature: 26533

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
7.2 %Met     (Translated Protein)
8.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
7.2 %Met     (Mature Protein)
8.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWKYMAALWLAFGGGFLSFISPCCLPLYPSFISYITGISVGDLKNRHAKHIKQSVMIHAA
CHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
AFLAGFSVIFYILGFSASSVGLLFLQYHNLIRMLGGIFFVVMGLFLLGVFRPAFMMKERR
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSIRKGKIGLLNSMLVGMIFAAGWTPCIGPIFGTIAYANFQNPDFGSAFMMITAYSLGFA
HHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
IPFLLMAFFIGNIRPLMKYSNMLMKIGGALMIVIGILLYTDNMIWINIWYSNLTNLF
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEHHHHCCCC
>Mature Secondary Structure
MWKYMAALWLAFGGGFLSFISPCCLPLYPSFISYITGISVGDLKNRHAKHIKQSVMIHAA
CHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
AFLAGFSVIFYILGFSASSVGLLFLQYHNLIRMLGGIFFVVMGLFLLGVFRPAFMMKERR
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSIRKGKIGLLNSMLVGMIFAAGWTPCIGPIFGTIAYANFQNPDFGSAFMMITAYSLGFA
HHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
IPFLLMAFFIGNIRPLMKYSNMLMKIGGALMIVIGILLYTDNMIWINIWYSNLTNLF
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969507; 9068642; 9384377; 10781554; 11844773 [H]