Click here to switch to the map view.

The map label for this gene is yvcE

Identifier: 52784169

GI number: 52784169

Start: 323849

End: 325207

Strand: Direct

Name: yvcE

Synonym: BLi00347

Alternate gene names: 52784169

Gene position: 323849-325207 (Clockwise)

Preceding gene: 52784167

Following gene: 52784172

Centisome position: 7.67

GC content: 45.18

Gene sequence:

>1359_bases
GTGAAGAAAAAGGTTTATACTTTTGGTTTAGCGTCGATTCTCGGAACAGCTAGTCTATTTACCCCCTTTATGAACAACAC
GGCATCGGCAGAAACATCTCAGCAAAAACAAGAAATTCAGCAAAAGCGTTCTGAAGTGAATTCAGGCATCGAGAGCAAGC
GGAAAGAAATCGCCAAGCTGCAAGACGAGCAGAAAAAGCTTGAAGGTAAAATCCAAGAGCTTGATAAAAAAGCACTTGAA
ACAAGCAACAAAATCGAAGACAAAGAAAAAGAAAACAAAAAAACGAAAAAAGAAGTGGAAGCTCTGAAAAAAGAAATCAA
AGAAACCGAAAAACGGATTGAAGAGCGTTCAAAAGTGATTAAAAATCGCGTGCGCAGCCTGCAGGAAAACGGCGGATCCC
AAAACTATTTGAATGTCCTTCTGGGCGCACAAAGCTTCGGAGATTTTATCACTCGTGCAACTGCTGTTTCAACAATTGTT
GATGCGGACAAAGACCTGCTTGACGAGCAGGAGAAAGATAAAAACAAGCTTGAAAAAGCAATGTCTGATTTAAATACAAA
ACTGGACGAAATCCAAAAAACACTAGCCGATTTAAAAACGCTTAAATCGGATCTTGATAAACAGCTGAAAGAACAGGCAA
ACCTTTCTAAGCAGCTGCAAACGAAGCAAGCGGCAGCAGAATCAGAACTGAGCGATCTGAAAAAAGAAGCGGGCTCTCTG
ACAAAAGAAGAAGCCGCTCTTGAACAAAAGCTTAAAGAAGAAAGAGCTGCGGCGGCTGCAGCAGCAAAAGCGAAAGAAGA
ATCTGCGACGGCTGAAAAGTCTGATTCAGGATCTTCATCAAGCTCAAATTCAGGTTCAGTCAGCAAATCTGACGGATCGT
CCAACAGCGGTTCTTCAAGCAGCAAGAAAAGCAGCAGCCCGTCAAGAAACTACTCTTCCGGTTCTGTTGTAAGCAGCAAT
GGAAACGCGATTGAAGCTGCCATCAGCACAGGTTCAAGCATTGTCGGCAGATCTCCGTACAAATGGGGAGGCGGACGTTC
ACAAGCTGATATCGACAACCGCCGCTTCGACTGCTCATCATTCGTACGCTGGGCTTATGCATCAGCAGGCGTAGAGCTTG
GATTCGGTGCGACAACAAGCACGCTTGTCGGCAAGGGACGAGCTGTCAGCGCGTCTGAAATGAAGCGCGGAGACTTGGTC
TTCTTTGACACATACAAAACGAACGGCCACGTGGGCATTTATCTTGGCAATGGCACATTCCTGAACGATAACAGCTCACG
CGGGGTATCCGTCGATTCTATGAGCAACCCGTACTGGAAGAAAGCTTTCAACGGAGTTGTAAGACGGGTCGTTGAATAA

Upstream 100 bases:

>100_bases
GATATATAAATCATAGGTCATAAGATTCATTTTTTAATAATGTTCAATCGAATTTACATAATGAAAAAACAAGAATACAT
AAAGGAAAGAGGAGTAGAAA

Downstream 100 bases:

>100_bases
AATATTATACTGAGACAAACGCCGTTCCCGATCGGGAGCGGCGTTTTTATTTTACAGCGGCAAGTCGCGCTTTTTAAAAA
TGAGAATGCTGAGTGCGAAG

Product: YvcE

Products: NA

Alternate protein names: D-gamma-glutamyl-meso-diaminopimelyl DL-endopeptidase

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MKKKVYTFGLASILGTASLFTPFMNNTASAETSQQKQEIQQKRSEVNSGIESKRKEIAKLQDEQKKLEGKIQELDKKALE
TSNKIEDKEKENKKTKKEVEALKKEIKETEKRIEERSKVIKNRVRSLQENGGSQNYLNVLLGAQSFGDFITRATAVSTIV
DADKDLLDEQEKDKNKLEKAMSDLNTKLDEIQKTLADLKTLKSDLDKQLKEQANLSKQLQTKQAAAESELSDLKKEAGSL
TKEEAALEQKLKEERAAAAAAAKAKEESATAEKSDSGSSSSSNSGSVSKSDGSSNSGSSSSKKSSSPSRNYSSGSVVSSN
GNAIEAAISTGSSIVGRSPYKWGGGRSQADIDNRRFDCSSFVRWAYASAGVELGFGATTSTLVGKGRAVSASEMKRGDLV
FFDTYKTNGHVGIYLGNGTFLNDNSSRGVSVDSMSNPYWKKAFNGVVRRVVE

Sequences:

>Translated_452_residues
MKKKVYTFGLASILGTASLFTPFMNNTASAETSQQKQEIQQKRSEVNSGIESKRKEIAKLQDEQKKLEGKIQELDKKALE
TSNKIEDKEKENKKTKKEVEALKKEIKETEKRIEERSKVIKNRVRSLQENGGSQNYLNVLLGAQSFGDFITRATAVSTIV
DADKDLLDEQEKDKNKLEKAMSDLNTKLDEIQKTLADLKTLKSDLDKQLKEQANLSKQLQTKQAAAESELSDLKKEAGSL
TKEEAALEQKLKEERAAAAAAAKAKEESATAEKSDSGSSSSSNSGSVSKSDGSSNSGSSSSKKSSSPSRNYSSGSVVSSN
GNAIEAAISTGSSIVGRSPYKWGGGRSQADIDNRRFDCSSFVRWAYASAGVELGFGATTSTLVGKGRAVSASEMKRGDLV
FFDTYKTNGHVGIYLGNGTFLNDNSSRGVSVDSMSNPYWKKAFNGVVRRVVE
>Mature_452_residues
MKKKVYTFGLASILGTASLFTPFMNNTASAETSQQKQEIQQKRSEVNSGIESKRKEIAKLQDEQKKLEGKIQELDKKALE
TSNKIEDKEKENKKTKKEVEALKKEIKETEKRIEERSKVIKNRVRSLQENGGSQNYLNVLLGAQSFGDFITRATAVSTIV
DADKDLLDEQEKDKNKLEKAMSDLNTKLDEIQKTLADLKTLKSDLDKQLKEQANLSKQLQTKQAAAESELSDLKKEAGSL
TKEEAALEQKLKEERAAAAAAAKAKEESATAEKSDSGSSSSSNSGSVSKSDGSSNSGSSSSKKSSSPSRNYSSGSVVSSN
GNAIEAAISTGSSIVGRSPYKWGGGRSQADIDNRRFDCSSFVRWAYASAGVELGFGATTSTLVGKGRAVSASEMKRGDLV
FFDTYKTNGHVGIYLGNGTFLNDNSSRGVSVDSMSNPYWKKAFNGVVRRVVE

Specific function: Shows a cell wall hydrolytic DL-endopeptidase activity

COG id: COG3883

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Secreted

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C40 family

Homologues:

Organism=Escherichia coli, GI1788501, Length=97, Percent_Identity=42.2680412371134, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787944, Length=117, Percent_Identity=34.1880341880342, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1786421, Length=136, Percent_Identity=30.8823529411765, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CWLO_BACLD (Q65NQ9)

Other databases:

- EMBL:   AE017333
- EMBL:   CP000002
- RefSeq:   YP_077590.1
- RefSeq:   YP_089998.1
- ProteinModelPortal:   Q65NQ9
- SMR:   Q65NQ9
- STRING:   Q65NQ9
- EnsemblBacteria:   EBBACT00000058149
- EnsemblBacteria:   EBBACT00000061389
- GeneID:   3027849
- GeneID:   3099461
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi00347
- KEGG:   bli:BL01691
- NMPDR:   fig|279010.5.peg.2200
- eggNOG:   COG3883
- GeneTree:   EBGT00050000000149
- HOGENOM:   HBG421016
- OMA:   QENGGSQ
- ProtClustDB:   CLSK887932
- BioCyc:   BLIC279010-1:BLI00347-MONOMER
- BioCyc:   BLIC279010:BL01691-MONOMER
- InterPro:   IPR000064

Pfam domain/function: PF00877 NLPC_P60

EC number: NA

Molecular weight: Translated: 49109; Mature: 49109

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: PS00801 TRANSKETOLASE_1

Important sites: ACT_SITE 358-358

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKVYTFGLASILGTASLFTPFMNNTASAETSQQKQEIQQKRSEVNSGIESKRKEIAKL
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
QDEQKKLEGKIQELDKKALETSNKIEDKEKENKKTKKEVEALKKEIKETEKRIEERSKVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KNRVRSLQENGGSQNYLNVLLGAQSFGDFITRATAVSTIVDADKDLLDEQEKDKNKLEKA
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
MSDLNTKLDEIQKTLADLKTLKSDLDKQLKEQANLSKQLQTKQAAAESELSDLKKEAGSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TKEEAALEQKLKEERAAAAAAAKAKEESATAEKSDSGSSSSSNSGSVSKSDGSSNSGSSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SKKSSSPSRNYSSGSVVSSNGNAIEAAISTGSSIVGRSPYKWGGGRSQADIDNRRFDCSS
CCCCCCCCCCCCCCCEECCCCCEEEHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCHHH
FVRWAYASAGVELGFGATTSTLVGKGRAVSASEMKRGDLVFFDTYKTNGHVGIYLGNGTF
HHHHHHHHCCCEECCCCCHHHHHCCCCCCCHHHHCCCCEEEEEEECCCCEEEEEECCCEE
LNDNSSRGVSVDSMSNPYWKKAFNGVVRRVVE
ECCCCCCCEECCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKKVYTFGLASILGTASLFTPFMNNTASAETSQQKQEIQQKRSEVNSGIESKRKEIAKL
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
QDEQKKLEGKIQELDKKALETSNKIEDKEKENKKTKKEVEALKKEIKETEKRIEERSKVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KNRVRSLQENGGSQNYLNVLLGAQSFGDFITRATAVSTIVDADKDLLDEQEKDKNKLEKA
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
MSDLNTKLDEIQKTLADLKTLKSDLDKQLKEQANLSKQLQTKQAAAESELSDLKKEAGSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TKEEAALEQKLKEERAAAAAAAKAKEESATAEKSDSGSSSSSNSGSVSKSDGSSNSGSSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SKKSSSPSRNYSSGSVVSSNGNAIEAAISTGSSIVGRSPYKWGGGRSQADIDNRRFDCSS
CCCCCCCCCCCCCCCEECCCCCEEEHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCHHH
FVRWAYASAGVELGFGATTSTLVGKGRAVSASEMKRGDLVFFDTYKTNGHVGIYLGNGTF
HHHHHHHHCCCEECCCCCHHHHHCCCCCCCHHHHCCCCEEEEEEECCCCEEEEEECCCEE
LNDNSSRGVSVDSMSNPYWKKAFNGVVRRVVE
ECCCCCCCEECCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA