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The map label for this gene is yfnB [H]

Identifier: 52784046

GI number: 52784046

Start: 195909

End: 196628

Strand: Direct

Name: yfnB [H]

Synonym: BLi00219

Alternate gene names: 52784046

Gene position: 195909-196628 (Clockwise)

Preceding gene: 52784045

Following gene: 52784047

Centisome position: 4.64

GC content: 41.81

Gene sequence:

>720_bases
GTGAAAAATTATCGTACTTTATTTTTTGATGTGGATGATACACTATTAGACTTCGGTGCGGCAGAAAAGTCAGCATTGCG
AATGCTTTTTGAGGAGCAGCAAATTCGTTTGACAGCTGAAATAGAAGCGAATTATAAACGAATCAATCAAGGTTTATGGA
GGGTGTTCGAAAAAGGGGAGATGGACCGCGACCAAGTGGTGAACACACGCTTTTCCCTTTTATTCAAAGAATATGGTCTT
GAGGCTGACGGCGTTTTGCTTGAGAAGAAGTATCGCAGCTTCCTTGAAGAAGGGCATCAGCTGATAGACGGCGCTTTTGA
ATTAATCAAAAGCCTGCGGGATCAATATGATTTATATATCGTGACGAACGGTGTTTCAAAAACGCAGTATAAGCGCCTGC
AAGCTTCAGGATTGTACCCGATGTTTAAAGGGATTTTTGTTTCAGAAGACACCGGTTTTCAAAAGCCGATGAAAGAATAC
TTTGATTACGTTTTTGAACGGATTCCTCATTTTTCTGTCGATCAGGGGCTGATCATCGGGGATTCATTGACAGCGGACAT
AGAAGGGGGGCGGCTGGCCGGATTGGATACATGCTGGATGAATCCGGGCATGATAGCAAATGACACTGGTATTGTACCAA
CCTATCAAATACAAAAACTTGATGAGTTGTATTATATTTTAAACATTGAAAAAGAATCGGCCGCCGGCCATTGTTTATAA

Upstream 100 bases:

>100_bases
GAGAAAGAAAAGGCAGAGACGATGAGCTTGCTGAAAAACGAGCTTGAAGCCATAAAAGACAGCAAGACCGGCTACTAAAA
TGCTAAACGGAGGAACACTC

Downstream 100 bases:

>100_bases
GGAAAAACGGGCGCATTTTGATTGGTTATTCAAGATGCGTACTGCTTTTTGATATTATAAGAATATTCTTTATATTGGGA
TAGTTGTTTCTTAATAAATA

Product: YfnB

Products: (R)-2-hydroxyacid; halide

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MKNYRTLFFDVDDTLLDFGAAEKSALRMLFEEQQIRLTAEIEANYKRINQGLWRVFEKGEMDRDQVVNTRFSLLFKEYGL
EADGVLLEKKYRSFLEEGHQLIDGAFELIKSLRDQYDLYIVTNGVSKTQYKRLQASGLYPMFKGIFVSEDTGFQKPMKEY
FDYVFERIPHFSVDQGLIIGDSLTADIEGGRLAGLDTCWMNPGMIANDTGIVPTYQIQKLDELYYILNIEKESAAGHCL

Sequences:

>Translated_239_residues
MKNYRTLFFDVDDTLLDFGAAEKSALRMLFEEQQIRLTAEIEANYKRINQGLWRVFEKGEMDRDQVVNTRFSLLFKEYGL
EADGVLLEKKYRSFLEEGHQLIDGAFELIKSLRDQYDLYIVTNGVSKTQYKRLQASGLYPMFKGIFVSEDTGFQKPMKEY
FDYVFERIPHFSVDQGLIIGDSLTADIEGGRLAGLDTCWMNPGMIANDTGIVPTYQIQKLDELYYILNIEKESAAGHCL
>Mature_239_residues
MKNYRTLFFDVDDTLLDFGAAEKSALRMLFEEQQIRLTAEIEANYKRINQGLWRVFEKGEMDRDQVVNTRFSLLFKEYGL
EADGVLLEKKYRSFLEEGHQLIDGAFELIKSLRDQYDLYIVTNGVSKTQYKRLQASGLYPMFKGIFVSEDTGFQKPMKEY
FDYVFERIPHFSVDQGLIIGDSLTADIEGGRLAGLDTCWMNPGMIANDTGIVPTYQIQKLDELYYILNIEKESAAGHCL

Specific function: Unknown

COG id: COG1011

COG function: function code R; Predicted hydrolase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. YjjG family [H]

Homologues:

Organism=Escherichia coli, GI1790833, Length=221, Percent_Identity=31.6742081447964, Blast_Score=118, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR011951 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: 3.8.1.2

Molecular weight: Translated: 27590; Mature: 27590

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNYRTLFFDVDDTLLDFGAAEKSALRMLFEEQQIRLTAEIEANYKRINQGLWRVFEKGE
CCCCEEEEEECCHHHHHCCCCHHHHHHHHHHHHHEEEEEEEHHHHHHHHHHHHHHHHCCC
MDRDQVVNTRFSLLFKEYGLEADGVLLEKKYRSFLEEGHQLIDGAFELIKSLRDQYDLYI
CCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
VTNGVSKTQYKRLQASGLYPMFKGIFVSEDTGFQKPMKEYFDYVFERIPHFSVDQGLIIG
EECCCCHHHHHHHHHCCCCHHHHCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEC
DSLTADIEGGRLAGLDTCWMNPGMIANDTGIVPTYQIQKLDELYYILNIEKESAAGHCL
CCEEEECCCCEEECCHHHCCCCCEEECCCCCCCCHHHHHHHHEEEEEEECCCCCCCCCC
>Mature Secondary Structure
MKNYRTLFFDVDDTLLDFGAAEKSALRMLFEEQQIRLTAEIEANYKRINQGLWRVFEKGE
CCCCEEEEEECCHHHHHCCCCHHHHHHHHHHHHHEEEEEEEHHHHHHHHHHHHHHHHCCC
MDRDQVVNTRFSLLFKEYGLEADGVLLEKKYRSFLEEGHQLIDGAFELIKSLRDQYDLYI
CCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
VTNGVSKTQYKRLQASGLYPMFKGIFVSEDTGFQKPMKEYFDYVFERIPHFSVDQGLIIG
EECCCCHHHHHHHHHCCCCHHHHCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEC
DSLTADIEGGRLAGLDTCWMNPGMIANDTGIVPTYQIQKLDELYYILNIEKESAAGHCL
CCEEEECCCCEEECCHHHCCCCCEEECCCCCCCCHHHHHHHHEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (S)-2-haloacid; H2O

Specific reaction: (S)-2-haloacid + H2O = (R)-2-hydroxyacid + halide

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]