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The map label for this gene is glmS

Identifier: 52784032

GI number: 52784032

Start: 183421

End: 185223

Strand: Direct

Name: glmS

Synonym: BLi00204

Alternate gene names: 52784032

Gene position: 183421-185223 (Clockwise)

Preceding gene: 52784031

Following gene: 52784033

Centisome position: 4.34

GC content: 50.14

Gene sequence:

>1803_bases
ATGTGTGGTATTGTAGGTTATATTGGCCAGCTTGATGCAAAGGAAATTTTACTTAAAGGTTTGGAGAAGCTGGAGTATCG
CGGCTACGATTCAGCTGGAATCGCTGTAGCGAACGAAGACGGCGTACACGTGTTTAAAGAAAAAGGACGGATCGCCGATC
TTCGCGCAGCCGTTGATGCAAACGTGAAGTCACAAGCGGGAATCGGACACACGCGCTGGGCGACTCACGGAGAACCGAGC
CGTCTAAACGCTCATCCGCATCAAAGCGCATCAGGCCGTTTTACACTTGTTCATAACGGCGTCATCGAAAACTATGTTCA
ACTGACGCGCGAATATTTACACGATGTAACCCTTAAAAGCGATACGGATACAGAGGTTGTCGTTCAAGTGATCGAGCAAT
TCGTCAATAACGGCCTTGACACAGAAGAAGCGTTCCGCCAAACGCTCATGCTGCTCAAAGGCTCTTATGCGATTGCATTA
TTCGATCATGAAAACAAAGAAACAATCTATGTTGCGAAAAATAAAAGCCCGCTTCTTGTCGGCCTTGGAGACAATTTCAA
TGTTGTCGCGTCTGATGCGATGGCGATGCTTCAAGTGACAAACGAATACGTGGAGCTTATGGATAAAGAAATGGTGATTG
TCACAGACAAAAAAGTCGTGATCAAAAACCTCGACGGAGAATTGATGTCACGTGCCTCATATATTGCAGAGCTTGATGCG
AGCGATATCGAAAAAGGCACATACCCTCACTACATGTTAAAAGAAATCGATGAACAGCCGCTTGTCATGCGGAAAATCAT
TCAGACGTACCAAGATGAAAACGGCAAGCTCTCCATTCCTGGAGACATTTCAAACGCTGTTGCTGAAGCCGACCGCGTCT
ATATCATTGCCTGCGGAACTAGCTACCATGCAGGTCTTGTCGGCAAGCAATTTATTGAAACATGGGCGAAAGTTCCGGCT
GAAGTCCATGTCGCAAGCGAATTCTCTTACAATATGCCATTGCTTTCTGAGAAGCCGCTGTTTATCTTTATTTCTCAAAG
CGGAGAAACGGCTGACAGCCGCGCGGTTCTCGTACAGGTGAAAAAGCTCGGACACAAAGCGCTGACATTGACCAACGTAC
CGGGATCCACGCTTTCCCGTGAAGCGGACTATACGCTTTTACTGAATGCCGGCCCTGAAATCGCGGTAGCGTCAACAAAA
GCATATACGGCGCAAATCGCCGTTCTCGCAATTTTGGCAGCCGTGACTGCGGAAAGCCGCGGCAAAGAACTCGGCTTTGA
TCTTGTCAAAGAGCTCGGCATTATCGGAAACGCGATGGAAGCCCTTTGCGACCAAAAAGACGAAATGGAAATGATCGCCC
GTGAATACTTGACCGTAACACGCAATGCATTTTTCATCGGCCGCGGCCTCGACTATTTCGTCTGCCTCGAAGGATCCCTG
AAGCTGAAAGAGATTTCTTACATTCAAGCTGAAGGCTTCGCCGGCGGCGAATTGAAGCACGGTACGATCGCATTGATCGA
AGACGGCACACCGGTCATCGCCCTTGCGACACAGGAGCACGTCAACTTAAGCATCCGCGGAAACGTCAAAGAAGTGACAG
CCCGCGGCGCCAACCCTTGCGTGATCTCCCTGAAAGGCCTGGAAGAAGCAGACGACCGCTTCGTCCTGCCTGAAGTGCAT
CCGGAGCTCGCACCGCTCGTCTCCGTCATCCCGCTGCAGCTGATCGCATACTACGCAGCGCTGCACCGCGGCTGTGACGT
TGATAAGCCACGGAACCTGGCGAAGAGTGTGACGGTGGAGTAG

Upstream 100 bases:

>100_bases
ATCTTCCATAAAAAACATGTAGGAGGGGACGATTGAAAGTCCCCGCCTGACAAGCAGACTTTCTTCGTCTCCTGCCTGCG
ACTTTAGGAGGAAGAAAATT

Downstream 100 bases:

>100_bases
GAGTCGGTTGAAATAAAAGTTTGTACCCCTCTTGGATTGGATGATCTGGAGGGGTATTTTTATGTTTGAAAGAGGAATAA
GTCTTATCAAAAATCGAAGT

Product: glucosamine--fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase

Number of amino acids: Translated: 600; Mature: 600

Protein sequence:

>600_residues
MCGIVGYIGQLDAKEILLKGLEKLEYRGYDSAGIAVANEDGVHVFKEKGRIADLRAAVDANVKSQAGIGHTRWATHGEPS
RLNAHPHQSASGRFTLVHNGVIENYVQLTREYLHDVTLKSDTDTEVVVQVIEQFVNNGLDTEEAFRQTLMLLKGSYAIAL
FDHENKETIYVAKNKSPLLVGLGDNFNVVASDAMAMLQVTNEYVELMDKEMVIVTDKKVVIKNLDGELMSRASYIAELDA
SDIEKGTYPHYMLKEIDEQPLVMRKIIQTYQDENGKLSIPGDISNAVAEADRVYIIACGTSYHAGLVGKQFIETWAKVPA
EVHVASEFSYNMPLLSEKPLFIFISQSGETADSRAVLVQVKKLGHKALTLTNVPGSTLSREADYTLLLNAGPEIAVASTK
AYTAQIAVLAILAAVTAESRGKELGFDLVKELGIIGNAMEALCDQKDEMEMIAREYLTVTRNAFFIGRGLDYFVCLEGSL
KLKEISYIQAEGFAGGELKHGTIALIEDGTPVIALATQEHVNLSIRGNVKEVTARGANPCVISLKGLEEADDRFVLPEVH
PELAPLVSVIPLQLIAYYAALHRGCDVDKPRNLAKSVTVE

Sequences:

>Translated_600_residues
MCGIVGYIGQLDAKEILLKGLEKLEYRGYDSAGIAVANEDGVHVFKEKGRIADLRAAVDANVKSQAGIGHTRWATHGEPS
RLNAHPHQSASGRFTLVHNGVIENYVQLTREYLHDVTLKSDTDTEVVVQVIEQFVNNGLDTEEAFRQTLMLLKGSYAIAL
FDHENKETIYVAKNKSPLLVGLGDNFNVVASDAMAMLQVTNEYVELMDKEMVIVTDKKVVIKNLDGELMSRASYIAELDA
SDIEKGTYPHYMLKEIDEQPLVMRKIIQTYQDENGKLSIPGDISNAVAEADRVYIIACGTSYHAGLVGKQFIETWAKVPA
EVHVASEFSYNMPLLSEKPLFIFISQSGETADSRAVLVQVKKLGHKALTLTNVPGSTLSREADYTLLLNAGPEIAVASTK
AYTAQIAVLAILAAVTAESRGKELGFDLVKELGIIGNAMEALCDQKDEMEMIAREYLTVTRNAFFIGRGLDYFVCLEGSL
KLKEISYIQAEGFAGGELKHGTIALIEDGTPVIALATQEHVNLSIRGNVKEVTARGANPCVISLKGLEEADDRFVLPEVH
PELAPLVSVIPLQLIAYYAALHRGCDVDKPRNLAKSVTVE
>Mature_600_residues
MCGIVGYIGQLDAKEILLKGLEKLEYRGYDSAGIAVANEDGVHVFKEKGRIADLRAAVDANVKSQAGIGHTRWATHGEPS
RLNAHPHQSASGRFTLVHNGVIENYVQLTREYLHDVTLKSDTDTEVVVQVIEQFVNNGLDTEEAFRQTLMLLKGSYAIAL
FDHENKETIYVAKNKSPLLVGLGDNFNVVASDAMAMLQVTNEYVELMDKEMVIVTDKKVVIKNLDGELMSRASYIAELDA
SDIEKGTYPHYMLKEIDEQPLVMRKIIQTYQDENGKLSIPGDISNAVAEADRVYIIACGTSYHAGLVGKQFIETWAKVPA
EVHVASEFSYNMPLLSEKPLFIFISQSGETADSRAVLVQVKKLGHKALTLTNVPGSTLSREADYTLLLNAGPEIAVASTK
AYTAQIAVLAILAAVTAESRGKELGFDLVKELGIIGNAMEALCDQKDEMEMIAREYLTVTRNAFFIGRGLDYFVCLEGSL
KLKEISYIQAEGFAGGELKHGTIALIEDGTPVIALATQEHVNLSIRGNVKEVTARGANPCVISLKGLEEADDRFVLPEVH
PELAPLVSVIPLQLIAYYAALHRGCDVDKPRNLAKSVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains

Homologues:

Organism=Homo sapiens, GI205277386, Length=684, Percent_Identity=33.0409356725146, Blast_Score=337, Evalue=2e-92,
Organism=Homo sapiens, GI4826742, Length=687, Percent_Identity=33.1877729257642, Blast_Score=332, Evalue=5e-91,
Organism=Homo sapiens, GI29570798, Length=144, Percent_Identity=32.6388888888889, Blast_Score=71, Evalue=3e-12,
Organism=Escherichia coli, GI1790167, Length=613, Percent_Identity=41.1092985318108, Blast_Score=435, Evalue=1e-123,
Organism=Escherichia coli, GI87082251, Length=302, Percent_Identity=20.1986754966887, Blast_Score=72, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17539970, Length=430, Percent_Identity=34.8837209302326, Blast_Score=237, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI17532899, Length=492, Percent_Identity=31.7073170731707, Blast_Score=224, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI17532897, Length=492, Percent_Identity=31.7073170731707, Blast_Score=224, Evalue=1e-58,
Organism=Saccharomyces cerevisiae, GI6322745, Length=452, Percent_Identity=32.9646017699115, Blast_Score=231, Evalue=2e-61,
Organism=Saccharomyces cerevisiae, GI6323731, Length=428, Percent_Identity=28.7383177570093, Blast_Score=167, Evalue=4e-42,
Organism=Saccharomyces cerevisiae, GI6323730, Length=205, Percent_Identity=34.1463414634146, Blast_Score=109, Evalue=1e-24,
Organism=Drosophila melanogaster, GI21357745, Length=689, Percent_Identity=32.8011611030479, Blast_Score=337, Evalue=2e-92,
Organism=Drosophila melanogaster, GI28573187, Length=239, Percent_Identity=28.0334728033473, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24659598, Length=241, Percent_Identity=26.5560165975104, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMS_BACLD (Q65P46)

Other databases:

- EMBL:   AE017333
- EMBL:   CP000002
- RefSeq:   YP_077461.1
- RefSeq:   YP_089861.1
- ProteinModelPortal:   Q65P46
- SMR:   Q65P46
- STRING:   Q65P46
- MEROPS:   C44.971
- EnsemblBacteria:   EBBACT00000057338
- EnsemblBacteria:   EBBACT00000059273
- GeneID:   3029128
- GeneID:   3099260
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi00204
- KEGG:   bli:BL02704
- NMPDR:   fig|279010.5.peg.1782
- eggNOG:   COG0449
- GeneTree:   EBGT00050000000004
- HOGENOM:   HBG645312
- OMA:   KNHSFVS
- ProtClustDB:   PRK00331
- BioCyc:   BLIC279010-1:BLI00204-MONOMER
- BioCyc:   BLIC279010:BL02704-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00164
- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347
- TIGRFAMs:   TIGR01135

Pfam domain/function: PF00310 GATase_2; PF01380 SIS

EC number: =2.6.1.16

Molecular weight: Translated: 65653; Mature: 65653

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS51278 GATASE_TYPE_2; PS51464 SIS; PS00443 GATASE_TYPE_II

Important sites: ACT_SITE 2-2 ACT_SITE 595-595

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIVGYIGQLDAKEILLKGLEKLEYRGYDSAGIAVANEDGVHVFKEKGRIADLRAAVDA
CCCHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCCCCEEEHHHHHCC
NVKSQAGIGHTRWATHGEPSRLNAHPHQSASGRFTLVHNGVIENYVQLTREYLHDVTLKS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHCCCCCC
DTDTEVVVQVIEQFVNNGLDTEEAFRQTLMLLKGSYAIALFDHENKETIYVAKNKSPLLV
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEEECCCCEEE
GLGDNFNVVASDAMAMLQVTNEYVELMDKEMVIVTDKKVVIKNLDGELMSRASYIAELDA
ECCCCCCEEHHHHHHHHHHHHHHHHHHCCCEEEEECCEEEEECCCHHHHHHHHHHHHCCH
SDIEKGTYPHYMLKEIDEQPLVMRKIIQTYQDENGKLSIPGDISNAVAEADRVYIIACGT
HHCCCCCCCHHHHHHCCCCCHHHHHHHHHHCCCCCEEECCCCHHHHHHCCCEEEEEEECC
SYHAGLVGKQFIETWAKVPAEVHVASEFSYNMPLLSEKPLFIFISQSGETADSRAVLVQV
CCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHH
KKLGHKALTLTNVPGSTLSREADYTLLLNAGPEIAVASTKAYTAQIAVLAILAAVTAESR
HHCCCEEEEEECCCCCCCCCCCCEEEEEECCCCEEEEECHHHHHHHHHHHHHHHHHHHCC
GKELGFDLVKELGIIGNAMEALCDQKDEMEMIAREYLTVTRNAFFIGRGLDYFVCLEGSL
CCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCEEEEECCCEEEEEECCCE
KLKEISYIQAEGFAGGELKHGTIALIEDGTPVIALATQEHVNLSIRGNVKEVTARGANPC
EEEEEEEEEECCCCCCCCCCCEEEEEECCCCEEEEEECCCEEEEEECCHHHHHCCCCCCE
VISLKGLEEADDRFVLPEVHPELAPLVSVIPLQLIAYYAALHRGCDVDKPRNLAKSVTVE
EEEECCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCC
>Mature Secondary Structure
MCGIVGYIGQLDAKEILLKGLEKLEYRGYDSAGIAVANEDGVHVFKEKGRIADLRAAVDA
CCCHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCCCCEEEHHHHHCC
NVKSQAGIGHTRWATHGEPSRLNAHPHQSASGRFTLVHNGVIENYVQLTREYLHDVTLKS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHCCCCCC
DTDTEVVVQVIEQFVNNGLDTEEAFRQTLMLLKGSYAIALFDHENKETIYVAKNKSPLLV
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEEECCCCEEE
GLGDNFNVVASDAMAMLQVTNEYVELMDKEMVIVTDKKVVIKNLDGELMSRASYIAELDA
ECCCCCCEEHHHHHHHHHHHHHHHHHHCCCEEEEECCEEEEECCCHHHHHHHHHHHHCCH
SDIEKGTYPHYMLKEIDEQPLVMRKIIQTYQDENGKLSIPGDISNAVAEADRVYIIACGT
HHCCCCCCCHHHHHHCCCCCHHHHHHHHHHCCCCCEEECCCCHHHHHHCCCEEEEEEECC
SYHAGLVGKQFIETWAKVPAEVHVASEFSYNMPLLSEKPLFIFISQSGETADSRAVLVQV
CCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHH
KKLGHKALTLTNVPGSTLSREADYTLLLNAGPEIAVASTKAYTAQIAVLAILAAVTAESR
HHCCCEEEEEECCCCCCCCCCCCEEEEEECCCCEEEEECHHHHHHHHHHHHHHHHHHHCC
GKELGFDLVKELGIIGNAMEALCDQKDEMEMIAREYLTVTRNAFFIGRGLDYFVCLEGSL
CCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCEEEEECCCEEEEEECCCE
KLKEISYIQAEGFAGGELKHGTIALIEDGTPVIALATQEHVNLSIRGNVKEVTARGANPC
EEEEEEEEEECCCCCCCCCCCEEEEEECCCCEEEEEECCCEEEEEECCHHHHHCCCCCCE
VISLKGLEEADDRFVLPEVHPELAPLVSVIPLQLIAYYAALHRGCDVDKPRNLAKSVTVE
EEEECCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA