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The map label for this gene is yclF [H]

Identifier: 52144623

GI number: 52144623

Start: 696097

End: 697482

Strand: Reverse

Name: yclF [H]

Synonym: BCZK0600

Alternate gene names: 52144623

Gene position: 697482-696097 (Counterclockwise)

Preceding gene: 52144619

Following gene: 52144627

Centisome position: 13.16

GC content: 37.23

Gene sequence:

>1386_bases
ATGGAATCAGCGATACAACTAGAAAAAGAACAACAAAGAAAAAAGAAACATCCTCCAGGTTTATACTTACTCTTCTTTAC
AGAAATGTGGGAGAGATTTAGTTACTATGGATTACGAGGATTATTAACATTATATTTAACGACAGCTTTAGTAAGCGGTG
GTCTTGGGTTTAGTCCCGCATGGGCACTCTCTATTTACGGATTTTATACTGGAGCCTGTTATTTCACACCAATGATTGGT
GGATACTTAACAGACCGTTTTCTAGGTAGACGAAAAGCGATCACAATTGGTGGTATAACAATGGCAATCGGTAACCTTAC
ACTATTTGCCTTGCAAAACCAAGTCGGCCTATACCTCGGATTAGCGCTTATTATTATTGGTAACGGATTCTTCAAACCAA
ATATCTCTACACTGGTTGGGGAATTATACGAAGAGAATGATCCAAAACGTGATAGTGCATTTACCATTTTCTATATGGGT
ATTAATGTCGGATCATTTTTAGCTCCACTCGTTTGCGGATTTTTATCAGAAAATTTATTCAAAACAACGGTTGATGGCGT
CGTACATTACGGATTCCGTTACGGATTTTTAGCCGCTTCAATCGGAATGATCATTGGACAAATTTTATTTACAACACTAT
CAAATCGCTTCCTTGGTGATATCGGTAAAAAACCAACTCGCGATTTACAAACAACAGATGGACAACCATCAGTAGGAGAT
ACACCGTTAACAAAAAAAGAAAAACAACGTACCGCAGTTATCGTCATTTTAACATGCTTCGTTGTCTTCTTCTGGGCTGG
CTTTGAACAAGCTGGTAGCTCATTAACATTATATACAAACAAATTTGTAGACCGCTCTGTGTTCGGATGGGAAGTTCCAA
CATCTTGGTTCCAATCGGTCAATCCATTATTTATTATTTTACTTGCTCCAGTTATTTCAGCATTATGGGCAAAACTTGCA
ACTCGCAAGCGCGGGGATTTAAAAATCCCAACAAAAATGGGACTTGGTATGATTTTGCTCGGTATCGGTTATATCATTCT
CGTTATCGCTACATTAAAAACAGGTAGTGATGAACATAACATTACAGAAAAAGCAAACTTACTATTTATCGTCTTTACGT
ATCTTTTCCATACGTTAGGTGAACTATTCTTATCACCTGTTGGACTATCAATGGTTAGTGCACTTGCTCCAGTAAAACTA
GCATCTTTACTAATGGGCGTATGGTTAGCGAGTTCAGGTATCGCTAACATTTTAGGTGGACAACTTGCAAGCTTCACAAC
TTCACTTGGATATGCTGAAGTATTTACAGTTATTGGAGCTGTAGCAATTGTATTAGGTTGTGTTTTATTACTAATTTCTA
AAAAATTAGTGAAATGGATGGATTAA

Upstream 100 bases:

>100_bases
GAAAAATCAACCTTTATTGACTTATAATAGTTAATAAGGTAAAATATTAAATGTACAAAATTATTAACTTTGTTTTTGTT
TGTGTCAGGAGGAAAATAAC

Downstream 100 bases:

>100_bases
AAAAAGATGAGGGATTTCCCTCATCTTTTTTATTTCTTCGCCTTCGTTCCTACTAAATCACCAGCAACAACATAACGCTT
AGAATTATCCTTAACAGATA

Product: peptide symporter family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MESAIQLEKEQQRKKKHPPGLYLLFFTEMWERFSYYGLRGLLTLYLTTALVSGGLGFSPAWALSIYGFYTGACYFTPMIG
GYLTDRFLGRRKAITIGGITMAIGNLTLFALQNQVGLYLGLALIIIGNGFFKPNISTLVGELYEENDPKRDSAFTIFYMG
INVGSFLAPLVCGFLSENLFKTTVDGVVHYGFRYGFLAASIGMIIGQILFTTLSNRFLGDIGKKPTRDLQTTDGQPSVGD
TPLTKKEKQRTAVIVILTCFVVFFWAGFEQAGSSLTLYTNKFVDRSVFGWEVPTSWFQSVNPLFIILLAPVISALWAKLA
TRKRGDLKIPTKMGLGMILLGIGYIILVIATLKTGSDEHNITEKANLLFIVFTYLFHTLGELFLSPVGLSMVSALAPVKL
ASLLMGVWLASSGIANILGGQLASFTTSLGYAEVFTVIGAVAIVLGCVLLLISKKLVKWMD

Sequences:

>Translated_461_residues
MESAIQLEKEQQRKKKHPPGLYLLFFTEMWERFSYYGLRGLLTLYLTTALVSGGLGFSPAWALSIYGFYTGACYFTPMIG
GYLTDRFLGRRKAITIGGITMAIGNLTLFALQNQVGLYLGLALIIIGNGFFKPNISTLVGELYEENDPKRDSAFTIFYMG
INVGSFLAPLVCGFLSENLFKTTVDGVVHYGFRYGFLAASIGMIIGQILFTTLSNRFLGDIGKKPTRDLQTTDGQPSVGD
TPLTKKEKQRTAVIVILTCFVVFFWAGFEQAGSSLTLYTNKFVDRSVFGWEVPTSWFQSVNPLFIILLAPVISALWAKLA
TRKRGDLKIPTKMGLGMILLGIGYIILVIATLKTGSDEHNITEKANLLFIVFTYLFHTLGELFLSPVGLSMVSALAPVKL
ASLLMGVWLASSGIANILGGQLASFTTSLGYAEVFTVIGAVAIVLGCVLLLISKKLVKWMD
>Mature_461_residues
MESAIQLEKEQQRKKKHPPGLYLLFFTEMWERFSYYGLRGLLTLYLTTALVSGGLGFSPAWALSIYGFYTGACYFTPMIG
GYLTDRFLGRRKAITIGGITMAIGNLTLFALQNQVGLYLGLALIIIGNGFFKPNISTLVGELYEENDPKRDSAFTIFYMG
INVGSFLAPLVCGFLSENLFKTTVDGVVHYGFRYGFLAASIGMIIGQILFTTLSNRFLGDIGKKPTRDLQTTDGQPSVGD
TPLTKKEKQRTAVIVILTCFVVFFWAGFEQAGSSLTLYTNKFVDRSVFGWEVPTSWFQSVNPLFIILLAPVISALWAKLA
TRKRGDLKIPTKMGLGMILLGIGYIILVIATLKTGSDEHNITEKANLLFIVFTYLFHTLGELFLSPVGLSMVSALAPVKL
ASLLMGVWLASSGIANILGGQLASFTTSLGYAEVFTVIGAVAIVLGCVLLLISKKLVKWMD

Specific function: Unknown

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family [H]

Homologues:

Organism=Homo sapiens, GI4827008, Length=383, Percent_Identity=26.1096605744125, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI226371746, Length=353, Percent_Identity=26.9121813031161, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI226371748, Length=344, Percent_Identity=25.8720930232558, Blast_Score=94, Evalue=3e-19,
Organism=Escherichia coli, GI1786927, Length=498, Percent_Identity=31.5261044176707, Blast_Score=217, Evalue=1e-57,
Organism=Escherichia coli, GI1790572, Length=489, Percent_Identity=30.0613496932515, Blast_Score=209, Evalue=4e-55,
Organism=Escherichia coli, GI1787922, Length=494, Percent_Identity=29.5546558704453, Blast_Score=204, Evalue=7e-54,
Organism=Escherichia coli, GI1789911, Length=496, Percent_Identity=27.6209677419355, Blast_Score=192, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI71987453, Length=376, Percent_Identity=25.2659574468085, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17569141, Length=166, Percent_Identity=31.3253012048193, Blast_Score=68, Evalue=9e-12,
Organism=Drosophila melanogaster, GI28571098, Length=398, Percent_Identity=27.1356783919598, Blast_Score=108, Evalue=7e-24,
Organism=Drosophila melanogaster, GI28571102, Length=398, Percent_Identity=26.6331658291457, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI28571100, Length=398, Percent_Identity=26.6331658291457, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24639581, Length=348, Percent_Identity=26.1494252873563, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24639585, Length=334, Percent_Identity=26.0479041916168, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24639583, Length=334, Percent_Identity=26.0479041916168, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 50534; Mature: 50534

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: PS00501 SPASE_I_1 ; PS50850 MFS ; PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESAIQLEKEQQRKKKHPPGLYLLFFTEMWERFSYYGLRGLLTLYLTTALVSGGLGFSPA
CCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
WALSIYGFYTGACYFTPMIGGYLTDRFLGRRKAITIGGITMAIGNLTLFALQNQVGLYLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHEEEHHHHHHHHHH
LALIIIGNGFFKPNISTLVGELYEENDPKRDSAFTIFYMGINVGSFLAPLVCGFLSENLF
HHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHH
KTTVDGVVHYGFRYGFLAASIGMIIGQILFTTLSNRFLGDIGKKPTRDLQTTDGQPSVGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
TPLTKKEKQRTAVIVILTCFVVFFWAGFEQAGSSLTLYTNKFVDRSVFGWEVPTSWFQSV
CCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHCCEEEEEEHHHHCCCCCCCCCCHHHHHCC
NPLFIILLAPVISALWAKLATRKRGDLKIPTKMGLGMILLGIGYIILVIATLKTGSDEHN
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
ITEKANLLFIVFTYLFHTLGELFLSPVGLSMVSALAPVKLASLLMGVWLASSGIANILGG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCC
QLASFTTSLGYAEVFTVIGAVAIVLGCVLLLISKKLVKWMD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MESAIQLEKEQQRKKKHPPGLYLLFFTEMWERFSYYGLRGLLTLYLTTALVSGGLGFSPA
CCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
WALSIYGFYTGACYFTPMIGGYLTDRFLGRRKAITIGGITMAIGNLTLFALQNQVGLYLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHEEEHHHHHHHHHH
LALIIIGNGFFKPNISTLVGELYEENDPKRDSAFTIFYMGINVGSFLAPLVCGFLSENLF
HHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHH
KTTVDGVVHYGFRYGFLAASIGMIIGQILFTTLSNRFLGDIGKKPTRDLQTTDGQPSVGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
TPLTKKEKQRTAVIVILTCFVVFFWAGFEQAGSSLTLYTNKFVDRSVFGWEVPTSWFQSV
CCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHCCEEEEEEHHHHCCCCCCCCCCHHHHHCC
NPLFIILLAPVISALWAKLATRKRGDLKIPTKMGLGMILLGIGYIILVIATLKTGSDEHN
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
ITEKANLLFIVFTYLFHTLGELFLSPVGLSMVSALAPVKLASLLMGVWLASSGIANILGG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCC
QLASFTTSLGYAEVFTVIGAVAIVLGCVLLLISKKLVKWMD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]