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The map label for this gene is feoB [H]

Identifier: 52144600

GI number: 52144600

Start: 721298

End: 722698

Strand: Reverse

Name: feoB [H]

Synonym: BCZK0622

Alternate gene names: 52144600

Gene position: 722698-721298 (Counterclockwise)

Preceding gene: 52144597

Following gene: 52144608

Centisome position: 13.63

GC content: 37.69

Gene sequence:

>1401_bases
ATGGAATCTCACTCAGCCAGTAAAGCTCTTCCATTAGACTATATTATTCAACACGCTCAAACACTTTCAAAAGAAGATAT
ACGAGATGATATTGTCGGAGATATTTATCGAACATCTGCAAGCATCTGTAAAGAATCTGTTCAATATACAAATACGGATA
AATTATATCGTTCTGAAAAACTAGATAAAATTTTCACATCTCCAATATGGGGATTCCCAATTATGCTCGGTATTTTATCT
ATCATTTTTTATCTTACAATCGCTGGTGCTAACGTACCATCTGATATGATTGCTGAGTTTTTCGGATGGGCCGAAGGATA
TTTAACTTCTTGGTTCCAAGCAGCACACGCACCTGAATGGTTACATGGCATTTTAATACTTGGTTTATTCCGTGGTATCG
GCGCTGTTATTAGCGTTATGTTACCACCTATGGCCATCTTTTTCCCTATGTTCGCACTATTAGAAAACTATGGATACTTA
CCACGCGTTGCGTTTAATATGGACCGCTTATTCAAACGCTCTGGTGCACACGGTAAACAATCTTTAACAATGGCAATGGG
CTTTGGTTGTAACGCTGCAGCTATTATGTCAACACGTATTATTGAATCACCACGTGAACGTATGCTTGCAATCTTAACAA
ATAACTTCGTACCTTGTAACGGTCGCTGGCCTATGTTAATTTTAATGGCCTCATTATTTATGGCTGCTGGTTATACAGGT
AGTATGCAAACACTTGTTACTGCCGGCGTTGTAGTTGGAATGGTTGTAATTGGTATCGTTATGACATTAACTGTTTCTTG
GGTACTATCCAAAACAGCTTTAAAAGGCGTTCCAACCCACTACACACTTGAGTTACCGCCGTACCGTAAGCCAAAGGTTT
GGAATACAATTGTGCGTGCAACACTCGATAAATCAGTTTATGTTTTAAAACGAGCTGTAGTTGTAGCTGCCCCTGCGGCT
GCATTAACTTGGTTACTTGCTAATATTTTCATCGGTGACACAAGTCTACTTATGTATTTTGTAAACTTCCTAGATCCATT
TGCTAAAATGTTAGGACTTGACGGCTTTATTCTAGCTGCTTTCATTCTTGGACTACCAGCGAATGAAATTGTTATCCCGA
TTTTATTAATGTCTTACTTATCAACCGGAGCTTTAACTGAAATAGATGATTTTAATCAAATTAAAAATTTATTCTTAGAA
AATGGTTGGACTTGGTTAACAGCGTTAAACACAATGTTGTTCTCACTTCTTCATTTCCCATGCGGAACAACACTGGTTAA
CATATATAAAGAAACAAAAAGTGCAAAATGGACATTCTTATCGTTTGCAATCCCTACCGTTATCGCCATTGTTGTAACAT
TCCTCTCTACACAATTGGTACATTGGTTAGGGCTTGTATAA

Upstream 100 bases:

>100_bases
GCACGTTGGATTGCATTACGTATATTAGATGGAGATAAAAATTTCTTAACTGCACTTGAAAAACATCATAACGAACCACT
TGTAAGGGAGGTCGTAATCA

Downstream 100 bases:

>100_bases
AGCAAAGCATACATAGAAGGTATCCCCCTTCACATATGCTTTGCACGAAAGAAACCTGAAATCATTCAGGTTTCTTTTTT
TGCACATCAGTATTCCAAGG

Product: ferrous iron transport protein B, C-terminal region

Products: Fe (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MESHSASKALPLDYIIQHAQTLSKEDIRDDIVGDIYRTSASICKESVQYTNTDKLYRSEKLDKIFTSPIWGFPIMLGILS
IIFYLTIAGANVPSDMIAEFFGWAEGYLTSWFQAAHAPEWLHGILILGLFRGIGAVISVMLPPMAIFFPMFALLENYGYL
PRVAFNMDRLFKRSGAHGKQSLTMAMGFGCNAAAIMSTRIIESPRERMLAILTNNFVPCNGRWPMLILMASLFMAAGYTG
SMQTLVTAGVVVGMVVIGIVMTLTVSWVLSKTALKGVPTHYTLELPPYRKPKVWNTIVRATLDKSVYVLKRAVVVAAPAA
ALTWLLANIFIGDTSLLMYFVNFLDPFAKMLGLDGFILAAFILGLPANEIVIPILLMSYLSTGALTEIDDFNQIKNLFLE
NGWTWLTALNTMLFSLLHFPCGTTLVNIYKETKSAKWTFLSFAIPTVIAIVVTFLSTQLVHWLGLV

Sequences:

>Translated_466_residues
MESHSASKALPLDYIIQHAQTLSKEDIRDDIVGDIYRTSASICKESVQYTNTDKLYRSEKLDKIFTSPIWGFPIMLGILS
IIFYLTIAGANVPSDMIAEFFGWAEGYLTSWFQAAHAPEWLHGILILGLFRGIGAVISVMLPPMAIFFPMFALLENYGYL
PRVAFNMDRLFKRSGAHGKQSLTMAMGFGCNAAAIMSTRIIESPRERMLAILTNNFVPCNGRWPMLILMASLFMAAGYTG
SMQTLVTAGVVVGMVVIGIVMTLTVSWVLSKTALKGVPTHYTLELPPYRKPKVWNTIVRATLDKSVYVLKRAVVVAAPAA
ALTWLLANIFIGDTSLLMYFVNFLDPFAKMLGLDGFILAAFILGLPANEIVIPILLMSYLSTGALTEIDDFNQIKNLFLE
NGWTWLTALNTMLFSLLHFPCGTTLVNIYKETKSAKWTFLSFAIPTVIAIVVTFLSTQLVHWLGLV
>Mature_466_residues
MESHSASKALPLDYIIQHAQTLSKEDIRDDIVGDIYRTSASICKESVQYTNTDKLYRSEKLDKIFTSPIWGFPIMLGILS
IIFYLTIAGANVPSDMIAEFFGWAEGYLTSWFQAAHAPEWLHGILILGLFRGIGAVISVMLPPMAIFFPMFALLENYGYL
PRVAFNMDRLFKRSGAHGKQSLTMAMGFGCNAAAIMSTRIIESPRERMLAILTNNFVPCNGRWPMLILMASLFMAAGYTG
SMQTLVTAGVVVGMVVIGIVMTLTVSWVLSKTALKGVPTHYTLELPPYRKPKVWNTIVRATLDKSVYVLKRAVVVAAPAA
ALTWLLANIFIGDTSLLMYFVNFLDPFAKMLGLDGFILAAFILGLPANEIVIPILLMSYLSTGALTEIDDFNQIKNLFLE
NGWTWLTALNTMLFSLLHFPCGTTLVNIYKETKSAKWTFLSFAIPTVIAIVVTFLSTQLVHWLGLV

Specific function: Not involved in Fe(2+) uptake but is involved in manganese uptake. Could be GTP-driven [H]

COG id: COG0370

COG function: function code P; Fe2+ transport system protein B

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1789813, Length=284, Percent_Identity=29.9295774647887, Blast_Score=114, Evalue=9e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011640
- InterPro:   IPR011619
- InterPro:   IPR011642
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF07664 FeoB_C; PF02421 FeoB_N; PF07670 Gate; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 51692; Mature: 51692

Theoretical pI: Translated: 8.54; Mature: 8.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESHSASKALPLDYIIQHAQTLSKEDIRDDIVGDIYRTSASICKESVQYTNTDKLYRSEK
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LDKIFTSPIWGFPIMLGILSIIFYLTIAGANVPSDMIAEFFGWAEGYLTSWFQAAHAPEW
HHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHH
LHGILILGLFRGIGAVISVMLPPMAIFFPMFALLENYGYLPRVAFNMDRLFKRSGAHGKQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHH
SLTMAMGFGCNAAAIMSTRIIESPRERMLAILTNNFVPCNGRWPMLILMASLFMAAGYTG
HHHHHHCCCCCHHHHHHHHHHHCHHHHHHHHHHCCEECCCCCCHHHHHHHHHHHHCCCCC
SMQTLVTAGVVVGMVVIGIVMTLTVSWVLSKTALKGVPTHYTLELPPYRKPKVWNTIVRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHH
TLDKSVYVLKRAVVVAAPAAALTWLLANIFIGDTSLLMYFVNFLDPFAKMLGLDGFILAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCHHHHHH
FILGLPANEIVIPILLMSYLSTGALTEIDDFNQIKNLFLENGWTWLTALNTMLFSLLHFP
HHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
CGTTLVNIYKETKSAKWTFLSFAIPTVIAIVVTFLSTQLVHWLGLV
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MESHSASKALPLDYIIQHAQTLSKEDIRDDIVGDIYRTSASICKESVQYTNTDKLYRSEK
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LDKIFTSPIWGFPIMLGILSIIFYLTIAGANVPSDMIAEFFGWAEGYLTSWFQAAHAPEW
HHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHH
LHGILILGLFRGIGAVISVMLPPMAIFFPMFALLENYGYLPRVAFNMDRLFKRSGAHGKQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHH
SLTMAMGFGCNAAAIMSTRIIESPRERMLAILTNNFVPCNGRWPMLILMASLFMAAGYTG
HHHHHHCCCCCHHHHHHHHHHHCHHHHHHHHHHCCEECCCCCCHHHHHHHHHHHHCCCCC
SMQTLVTAGVVVGMVVIGIVMTLTVSWVLSKTALKGVPTHYTLELPPYRKPKVWNTIVRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHH
TLDKSVYVLKRAVVVAAPAAALTWLLANIFIGDTSLLMYFVNFLDPFAKMLGLDGFILAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCHHHHHH
FILGLPANEIVIPILLMSYLSTGALTEIDDFNQIKNLFLENGWTWLTALNTMLFSLLHFP
HHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
CGTTLVNIYKETKSAKWTFLSFAIPTVIAIVVTFLSTQLVHWLGLV
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Fe (II) [Periplasm] [C]

Specific reaction: Fe (II) [Periplasm] = Fe (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12949112 [H]