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The map label for this gene is yhfN [H]

Identifier: 52144204

GI number: 52144204

Start: 1128916

End: 1130235

Strand: Direct

Name: yhfN [H]

Synonym: BCZK1023

Alternate gene names: 52144204

Gene position: 1128916-1130235 (Clockwise)

Preceding gene: 52144205

Following gene: 52144203

Centisome position: 21.3

GC content: 37.42

Gene sequence:

>1320_bases
ATGTACGAACTTACAATAATAATAGACAGGCAGCATAGAGGAGGGAATAGCGTGAGGAAGGTTATTGGGTGGTCGCTTTT
TTTGTACGTTGGGTTTGCGTTATTTATATATTGGTATTTATTTGGATGGAGTCATGAACTGATTCCGGACATGTATAAAG
GAACGAGTGCAGATCCAGAAACGTTTATGAATGCAAGAGAGCTTACGCTAAGCCAAGATTATTCGCGGGTGAAAAATTTA
CTGTACTTTTTAGCGACGCCTCTAGAATGGATTATATTATTGTTTGTACTTGTGCTCGGTGTTTCGAAAAAGTTTGAGAA
ATGGTCGAAGGAAACGACGAAAATAAGTGTTCTGCAAGTTGCGATTTATTTCTTTTATTTATCACTACTCACAACAGTTC
TTGCCTTGCCGATGCAATGGATTAGCCGAAAAGTGTCCGTTGATTACGGCATTTCAACGCAAAGTACACAAAGCTGGATA
AAAGATCACGTTATCGGTTTTTGGGAAAGTTATGCGACGATGTTAATTGTAGTTGCCGTTCTGTTATGGCTTATCCGTAA
ATTCCCGAAGAGATGGTGGCTAGCAGGGTGGGCGCTCTCTGTACCATTTACAATCTTTTTAACATTTATACAGCCTGTCG
TTATTGATCCACTTTATAACGACTTTTCGACGCTGAAAAATAAGGAATTAGAAACGAAAATTTTAGCGATAGCAGATAAA
GCGGACATTCCTGCTAAACACGTGTATGAAGTAAATATGTCAGAGAAAACGAATGCGTTAAATGCATATGTAACAGGAAT
TGGCCCTAACGCTCGTATTGTAATGTGGGATACGACGCTTAAGCAATTAAAAGATAAAGAGATTTTATTTATAATGGCCC
ATGAAATGGGGCATTACGTTATGAAACATATATATTGGGGCGTTGCGAGTTATGTATTGTTATCGTTTATAGGGATGTAT
CTCATTAGTCGTATTATAAATATGTGTATTCGAAAATGGGGAGATACGCTGCAAGTTTCAAAAGCAGCATGTTTCTCAAT
TTTACCTTTATTTTTCTTAATTTCTTCTGTACTCTCTTTTGCATCACAGCCAGCAACAAACTATGTTTCTCGTATAGAAG
AACGAGCGGCAGATCAATATGCTTTAGACATGACGAAAGACGGGAAATCTGGTGTAAAGACGTTTCAATATTTATCAAAA
ACGAGCTTAAGCCAAGTAAATCCGCCTGCGTTAGTAAAGTTTTTCTTATATACACACCCACCAATTTTTGAAAGAATTCA
TGCGTTTGAACAGTATGAGAAACAAAGCAAAAAGAAGTAG

Upstream 100 bases:

>100_bases
TGTCTAAAGGTAGGTAAAACTCTTCTTTATGTAGAAGAGTTTTTTTATGTAAATAGAGGGTTCTTGAGCAATTTGCATAA
TAAGCTTGTTCTAATTTAGC

Downstream 100 bases:

>100_bases
CTACTATGCTACTTCTTTTTTTATAGAGATATAAGTTTGATATTGGGAATATTTATCATTGCTTTTTATTGTGATTTTGT
AAATAATAAGCTATAAAATT

Product: metalloprotease

Products: NA

Alternate protein names: PSP23 [H]

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MYELTIIIDRQHRGGNSVRKVIGWSLFLYVGFALFIYWYLFGWSHELIPDMYKGTSADPETFMNARELTLSQDYSRVKNL
LYFLATPLEWIILLFVLVLGVSKKFEKWSKETTKISVLQVAIYFFYLSLLTTVLALPMQWISRKVSVDYGISTQSTQSWI
KDHVIGFWESYATMLIVVAVLLWLIRKFPKRWWLAGWALSVPFTIFLTFIQPVVIDPLYNDFSTLKNKELETKILAIADK
ADIPAKHVYEVNMSEKTNALNAYVTGIGPNARIVMWDTTLKQLKDKEILFIMAHEMGHYVMKHIYWGVASYVLLSFIGMY
LISRIINMCIRKWGDTLQVSKAACFSILPLFFLISSVLSFASQPATNYVSRIEERAADQYALDMTKDGKSGVKTFQYLSK
TSLSQVNPPALVKFFLYTHPPIFERIHAFEQYEKQSKKK

Sequences:

>Translated_439_residues
MYELTIIIDRQHRGGNSVRKVIGWSLFLYVGFALFIYWYLFGWSHELIPDMYKGTSADPETFMNARELTLSQDYSRVKNL
LYFLATPLEWIILLFVLVLGVSKKFEKWSKETTKISVLQVAIYFFYLSLLTTVLALPMQWISRKVSVDYGISTQSTQSWI
KDHVIGFWESYATMLIVVAVLLWLIRKFPKRWWLAGWALSVPFTIFLTFIQPVVIDPLYNDFSTLKNKELETKILAIADK
ADIPAKHVYEVNMSEKTNALNAYVTGIGPNARIVMWDTTLKQLKDKEILFIMAHEMGHYVMKHIYWGVASYVLLSFIGMY
LISRIINMCIRKWGDTLQVSKAACFSILPLFFLISSVLSFASQPATNYVSRIEERAADQYALDMTKDGKSGVKTFQYLSK
TSLSQVNPPALVKFFLYTHPPIFERIHAFEQYEKQSKKK
>Mature_439_residues
MYELTIIIDRQHRGGNSVRKVIGWSLFLYVGFALFIYWYLFGWSHELIPDMYKGTSADPETFMNARELTLSQDYSRVKNL
LYFLATPLEWIILLFVLVLGVSKKFEKWSKETTKISVLQVAIYFFYLSLLTTVLALPMQWISRKVSVDYGISTQSTQSWI
KDHVIGFWESYATMLIVVAVLLWLIRKFPKRWWLAGWALSVPFTIFLTFIQPVVIDPLYNDFSTLKNKELETKILAIADK
ADIPAKHVYEVNMSEKTNALNAYVTGIGPNARIVMWDTTLKQLKDKEILFIMAHEMGHYVMKHIYWGVASYVLLSFIGMY
LISRIINMCIRKWGDTLQVSKAACFSILPLFFLISSVLSFASQPATNYVSRIEERAADQYALDMTKDGKSGVKTFQYLSK
TSLSQVNPPALVKFFLYTHPPIFERIHAFEQYEKQSKKK

Specific function: Unknown

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Homo sapiens, GI18379366, Length=434, Percent_Identity=22.3502304147465, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17505484, Length=438, Percent_Identity=21.4611872146119, Blast_Score=88, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6322577, Length=323, Percent_Identity=26.3157894736842, Blast_Score=97, Evalue=5e-21,
Organism=Drosophila melanogaster, GI19922414, Length=270, Percent_Identity=21.1111111111111, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: NA

Molecular weight: Translated: 50864; Mature: 50864

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: PS00142 ZINC_PROTEASE ; PS00678 WD_REPEATS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYELTIIIDRQHRGGNSVRKVIGWSLFLYVGFALFIYWYLFGWSHELIPDMYKGTSADPE
CEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHH
TFMNARELTLSQDYSRVKNLLYFLATPLEWIILLFVLVLGVSKKFEKWSKETTKISVLQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
AIYFFYLSLLTTVLALPMQWISRKVSVDYGISTQSTQSWIKDHVIGFWESYATMLIVVAV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLWLIRKFPKRWWLAGWALSVPFTIFLTFIQPVVIDPLYNDFSTLKNKELETKILAIADK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHEEECC
ADIPAKHVYEVNMSEKTNALNAYVTGIGPNARIVMWDTTLKQLKDKEILFIMAHEMGHYV
CCCCHHHEEEECCCCCCCCHHEEEEEECCCCEEEEECCHHHHCCCCCEEEEEHHHHHHHH
MKHIYWGVASYVLLSFIGMYLISRIINMCIRKWGDTLQVSKAACFSILPLFFLISSVLSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ASQPATNYVSRIEERAADQYALDMTKDGKSGVKTFQYLSKTSLSQVNPPALVKFFLYTHP
HCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
PIFERIHAFEQYEKQSKKK
HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYELTIIIDRQHRGGNSVRKVIGWSLFLYVGFALFIYWYLFGWSHELIPDMYKGTSADPE
CEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHH
TFMNARELTLSQDYSRVKNLLYFLATPLEWIILLFVLVLGVSKKFEKWSKETTKISVLQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
AIYFFYLSLLTTVLALPMQWISRKVSVDYGISTQSTQSWIKDHVIGFWESYATMLIVVAV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLWLIRKFPKRWWLAGWALSVPFTIFLTFIQPVVIDPLYNDFSTLKNKELETKILAIADK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHEEECC
ADIPAKHVYEVNMSEKTNALNAYVTGIGPNARIVMWDTTLKQLKDKEILFIMAHEMGHYV
CCCCHHHEEEECCCCCCCCHHEEEEEECCCCEEEEECCHHHHCCCCCEEEEEHHHHHHHH
MKHIYWGVASYVLLSFIGMYLISRIINMCIRKWGDTLQVSKAACFSILPLFFLISSVLSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ASQPATNYVSRIEERAADQYALDMTKDGKSGVKTFQYLSKTSLSQVNPPALVKFFLYTHP
HCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
PIFERIHAFEQYEKQSKKK
HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 3145906 [H]