Click here to switch to the map view.

The map label for this gene is aceB [H]

Identifier: 52144200

GI number: 52144200

Start: 1136237

End: 1137826

Strand: Direct

Name: aceB [H]

Synonym: BCZK1029

Alternate gene names: 52144200

Gene position: 1136237-1137826 (Clockwise)

Preceding gene: 52144199

Following gene: 52144197

Centisome position: 21.43

GC content: 38.93

Gene sequence:

>1590_bases
ATGTCGACGCAAACTTCACGGGTTACACTCGTGGGAGAAATGTTACCAGCGTACAACGAAATATTGACACCTGAGGCGCT
TAGTTTTTTGAAGGAACTACATGGAAATTTCAATGAGCGCCGCATAGAACTTTTACAAAAGCGTGCTGAGAAACAAAAGA
GAATTGATGCAGGGGAGTTTCCGAAGTTTTTAGAAGAAACGAAGCACATACGTGAAGCGGATTGGACAATTGCTAAATTG
CCAAAAGATTTAGAGGATCGCCGCGTAGAGATTACTGGTCCAGTAGATAGAAAGATGGTTATTAACGCTTTAAATTCAGG
AGCACATCTTTTTATGGCGGATTTTGAAGATTCGAATTCACCAACTTGGGAAAATGCGATTGAAGGTCAAATAAACTTAC
GAGATGCAGTAAGGGGAACGATTTCACATAAAAATGAAAACGGAAAAGAATATCGTTTAAATAGTAAAACAGCTGTATTA
ATTGTGCGTCCAAGGGGATGGCATTTAGAAGAAAAACATATGCAAGTTGACGGAAAGAATATGTCGGGTAGCTTAGTAGA
TTTCGGACTTTATTTTTTCCATAATGCGAAAGCTCTTTTAGAAAAAGGAAGCGGTCCATACTTTTACTTACCGAAAATGG
AAAGCTATTTAGAAGCAAGATTATGGAATGATGTTTTCGTATTTGCTCAAAAATATATCGGTATTCCAAACGGAACGATT
AAAGCAACGGTGTTACTGGAAACGATTCACGCTTCGTTTGAAATGGATGAAATTTTGTATGAGCTTAAAGATCATTCTGC
CGGATTAAATTGCGGAAGATGGGATTATATTTTTAGTTTTCTAAAGGCTTTCCGTAATCATAATGAATTTTTACTTCCTG
ATAGAGCGCAAGTCACGATGACGGCGCCGTTTATGCGCGCGTATTCTTTGAAAGTCATTCAAACTTGTCACCGCCGTAAT
GCACCAGCTATTGGAGGGATGGCAGCACAAATTCCGATTAAAAACAATCCAAAAGCAAATGAAGCTGCTTTTGAAAAAGT
GCGTGCTGATAAGGAGCGCGAAGCTTTAGACGGTCACGACGGGACTTGGGTTGCCCACCCGGGACTTGTGCCAGTCGCGA
TGGAAGTATTTAATCACATTATGAAAACGCCGAATCAAATTTTTAGAAAACGTGAAGAAATACATGTTACAGAAAAGGAT
TTATTAGAAGTACCAGTGGGAACGATTACAGAAGAGGGTCTTCGTATGAATATTAGCGTAGGCATTCAATATATCGCATC
TTGGTTAAGCGGACGGGGAGCAGCACCAATTTATAACTTAATGGAAGATGCGGCAACAGCGGAAATTTCTAGGGCACAAG
TATGGCAATGGATTCGCCATGAAGGTGGAAAATTAAATGATGGCCGTAATATTACACTTGAATTAATGGAAGAGCTAAAA
GAAGAAGAGTTAGAAAAAATAGAAAGAGAGATTGGTAAAGAAGCCTTTAAGAAAGGGAGATTCCAAGAGGCGACAACGTT
ATTTACAAATCTCGTTCGGAATGATGAATTCGTACCATTTTTAACATTACCGGGTTATGAAATTTTATAA

Upstream 100 bases:

>100_bases
ATGAATTTTCAAAAAAAACTTCCTTTTCTGAAGATTTGTTATATAATATAAAACATAAAATCAAATCTGTTATAAAACAG
TTTAAGAAGGGGATGCTAAT

Downstream 100 bases:

>100_bases
AAAGTGAAAAGGGGATGGAACAAATGAAAAACGAAAGAATCGAGAAATTACAAGAAAGCTGGGAACTAGATACGCGCTGG
AAAGGGATCACACGTCCATA

Product: malate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 529; Mature: 528

Protein sequence:

>529_residues
MSTQTSRVTLVGEMLPAYNEILTPEALSFLKELHGNFNERRIELLQKRAEKQKRIDAGEFPKFLEETKHIREADWTIAKL
PKDLEDRRVEITGPVDRKMVINALNSGAHLFMADFEDSNSPTWENAIEGQINLRDAVRGTISHKNENGKEYRLNSKTAVL
IVRPRGWHLEEKHMQVDGKNMSGSLVDFGLYFFHNAKALLEKGSGPYFYLPKMESYLEARLWNDVFVFAQKYIGIPNGTI
KATVLLETIHASFEMDEILYELKDHSAGLNCGRWDYIFSFLKAFRNHNEFLLPDRAQVTMTAPFMRAYSLKVIQTCHRRN
APAIGGMAAQIPIKNNPKANEAAFEKVRADKEREALDGHDGTWVAHPGLVPVAMEVFNHIMKTPNQIFRKREEIHVTEKD
LLEVPVGTITEEGLRMNISVGIQYIASWLSGRGAAPIYNLMEDAATAEISRAQVWQWIRHEGGKLNDGRNITLELMEELK
EEELEKIEREIGKEAFKKGRFQEATTLFTNLVRNDEFVPFLTLPGYEIL

Sequences:

>Translated_529_residues
MSTQTSRVTLVGEMLPAYNEILTPEALSFLKELHGNFNERRIELLQKRAEKQKRIDAGEFPKFLEETKHIREADWTIAKL
PKDLEDRRVEITGPVDRKMVINALNSGAHLFMADFEDSNSPTWENAIEGQINLRDAVRGTISHKNENGKEYRLNSKTAVL
IVRPRGWHLEEKHMQVDGKNMSGSLVDFGLYFFHNAKALLEKGSGPYFYLPKMESYLEARLWNDVFVFAQKYIGIPNGTI
KATVLLETIHASFEMDEILYELKDHSAGLNCGRWDYIFSFLKAFRNHNEFLLPDRAQVTMTAPFMRAYSLKVIQTCHRRN
APAIGGMAAQIPIKNNPKANEAAFEKVRADKEREALDGHDGTWVAHPGLVPVAMEVFNHIMKTPNQIFRKREEIHVTEKD
LLEVPVGTITEEGLRMNISVGIQYIASWLSGRGAAPIYNLMEDAATAEISRAQVWQWIRHEGGKLNDGRNITLELMEELK
EEELEKIEREIGKEAFKKGRFQEATTLFTNLVRNDEFVPFLTLPGYEIL
>Mature_528_residues
STQTSRVTLVGEMLPAYNEILTPEALSFLKELHGNFNERRIELLQKRAEKQKRIDAGEFPKFLEETKHIREADWTIAKLP
KDLEDRRVEITGPVDRKMVINALNSGAHLFMADFEDSNSPTWENAIEGQINLRDAVRGTISHKNENGKEYRLNSKTAVLI
VRPRGWHLEEKHMQVDGKNMSGSLVDFGLYFFHNAKALLEKGSGPYFYLPKMESYLEARLWNDVFVFAQKYIGIPNGTIK
ATVLLETIHASFEMDEILYELKDHSAGLNCGRWDYIFSFLKAFRNHNEFLLPDRAQVTMTAPFMRAYSLKVIQTCHRRNA
PAIGGMAAQIPIKNNPKANEAAFEKVRADKEREALDGHDGTWVAHPGLVPVAMEVFNHIMKTPNQIFRKREEIHVTEKDL
LEVPVGTITEEGLRMNISVGIQYIASWLSGRGAAPIYNLMEDAATAEISRAQVWQWIRHEGGKLNDGRNITLELMEELKE
EELEKIEREIGKEAFKKGRFQEATTLFTNLVRNDEFVPFLTLPGYEIL

Specific function: Glyoxylate bypass; second step. [C]

COG id: COG2225

COG function: function code C; Malate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the malate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1790444, Length=512, Percent_Identity=54.8828125, Blast_Score=570, Evalue=1e-164,
Organism=Caenorhabditis elegans, GI17561814, Length=525, Percent_Identity=56, Blast_Score=589, Evalue=1e-168,
Organism=Caenorhabditis elegans, GI71982926, Length=418, Percent_Identity=59.0909090909091, Blast_Score=508, Evalue=1e-144,
Organism=Saccharomyces cerevisiae, GI6324212, Length=515, Percent_Identity=51.8446601941748, Blast_Score=532, Evalue=1e-152,
Organism=Saccharomyces cerevisiae, GI6322222, Length=516, Percent_Identity=51.3565891472868, Blast_Score=521, Evalue=1e-148,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011076
- InterPro:   IPR006252
- InterPro:   IPR001465
- InterPro:   IPR019830 [H]

Pfam domain/function: PF01274 Malate_synthase [H]

EC number: =2.3.3.9 [H]

Molecular weight: Translated: 60532; Mature: 60401

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS00510 MALATE_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTQTSRVTLVGEMLPAYNEILTPEALSFLKELHGNFNERRIELLQKRAEKQKRIDAGEF
CCCCCCCEEHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCC
PKFLEETKHIREADWTIAKLPKDLEDRRVEITGPVDRKMVINALNSGAHLFMADFEDSNS
HHHHHHHHHHHHCCCHHHHCCCCCCCCEEEEECCCCHHHHHHHHCCCCEEEEEECCCCCC
PTWENAIEGQINLRDAVRGTISHKNENGKEYRLNSKTAVLIVRPRGWHLEEKHMQVDGKN
CCCHHHCCCCEEHHHHHHHHHCCCCCCCCEEEECCCEEEEEECCCCCCCCHHHHEECCCC
MSGSLVDFGLYFFHNAKALLEKGSGPYFYLPKMESYLEARLWNDVFVFAQKYIGIPNGTI
CCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCE
KATVLLETIHASFEMDEILYELKDHSAGLNCGRWDYIFSFLKAFRNHNEFLLPDRAQVTM
EHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEECCCCCCEEE
TAPFMRAYSLKVIQTCHRRNAPAIGGMAAQIPIKNNPKANEAAFEKVRADKEREALDGHD
ECHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCHHHHHHHHHCCHHHHHCCCCC
GTWVAHPGLVPVAMEVFNHIMKTPNQIFRKREEIHVTEKDLLEVPVGTITEEGLRMNISV
CCEEECCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCEEEEHHH
GIQYIASWLSGRGAAPIYNLMEDAATAEISRAQVWQWIRHEGGKLNDGRNITLELMEELK
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
EEELEKIEREIGKEAFKKGRFQEATTLFTNLVRNDEFVPFLTLPGYEIL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCC
>Mature Secondary Structure 
STQTSRVTLVGEMLPAYNEILTPEALSFLKELHGNFNERRIELLQKRAEKQKRIDAGEF
CCCCCCEEHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCC
PKFLEETKHIREADWTIAKLPKDLEDRRVEITGPVDRKMVINALNSGAHLFMADFEDSNS
HHHHHHHHHHHHCCCHHHHCCCCCCCCEEEEECCCCHHHHHHHHCCCCEEEEEECCCCCC
PTWENAIEGQINLRDAVRGTISHKNENGKEYRLNSKTAVLIVRPRGWHLEEKHMQVDGKN
CCCHHHCCCCEEHHHHHHHHHCCCCCCCCEEEECCCEEEEEECCCCCCCCHHHHEECCCC
MSGSLVDFGLYFFHNAKALLEKGSGPYFYLPKMESYLEARLWNDVFVFAQKYIGIPNGTI
CCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCE
KATVLLETIHASFEMDEILYELKDHSAGLNCGRWDYIFSFLKAFRNHNEFLLPDRAQVTM
EHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEECCCCCCEEE
TAPFMRAYSLKVIQTCHRRNAPAIGGMAAQIPIKNNPKANEAAFEKVRADKEREALDGHD
ECHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCHHHHHHHHHCCHHHHHCCCCC
GTWVAHPGLVPVAMEVFNHIMKTPNQIFRKREEIHVTEKDLLEVPVGTITEEGLRMNISV
CCEEECCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCEEEEHHH
GIQYIASWLSGRGAAPIYNLMEDAATAEISRAQVWQWIRHEGGKLNDGRNITLELMEELK
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
EEELEKIEREIGKEAFKKGRFQEATTLFTNLVRNDEFVPFLTLPGYEIL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA