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The map label for this gene is comK [H]

Identifier: 52144194

GI number: 52144194

Start: 1141853

End: 1142434

Strand: Direct

Name: comK [H]

Synonym: BCZK1035

Alternate gene names: 52144194

Gene position: 1141853-1142434 (Clockwise)

Preceding gene: 52144195

Following gene: 52144191

Centisome position: 21.54

GC content: 33.85

Gene sequence:

>582_bases
ATGGAGAATAAAGTGGAACGCTACGTCGAAAACTATGTGGTAAATAAAAATACAATGGCCTTACTTCCTGTAATTCTCAG
TGAAAAGAAAATTGTCACGCGAGTTGTTGAAGTGCAAGACTCTTTTTTCGTATTTCAAAAGCCTCTAGATATTATAGAAA
GAAGTTGTCGCAAGCATGGTTCTAGTTTTTTAGGTAGAAAAGAAGGAACGAAAGAGTTAACTCATATTACCCATAAAGCT
CCAATTGCGATTAGTCCAACCGATCAACTTTATTTTTTCCCTACTTATTCTTATTCTAGAAAAGAATGCGCGTGGCTGTC
TCATTTTTATATTGAAAGCAATAAAGAATTAAAAGATGGAAACCTTATTATTCGATTTATAAATGGCTTTGCGGTGAAGT
TAGAGATATCGAAAACTAGCTTTGAAAATCAACAAAATCGTACAGCAAAATTGCGTACTGAGTATGAAGATCGTAGGAAA
AAACAAGGGAATCCTTGTTTTAAAGAGGTTGATAAAAAGGAAGAATCTAGATTAAAACCAGCATATGAGAGTGTGTATTT
TGTGAAAGAAGAAGAGGTGTGA

Upstream 100 bases:

>100_bases
GTATTGTAAAAAAGCGGAATCGGTAAGCCATTTCCTTTTCATAGATGCTAAAATTATACATGCAGCTGCTAATATAAATA
GAAAAAGGAGATAGTGCAAT

Downstream 100 bases:

>100_bases
AAGGATGGGGAACCCCCATCCTTTTTATTTCTTAGTAAGTGGATATATTGGAGAAATCGCAAATGCAAAAAAATCCATTT
CCTAAATAACCAAGTTCACG

Product: competence transcription factor

Products: NA

Alternate protein names: CTF; Competence protein K [H]

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MENKVERYVENYVVNKNTMALLPVILSEKKIVTRVVEVQDSFFVFQKPLDIIERSCRKHGSSFLGRKEGTKELTHITHKA
PIAISPTDQLYFFPTYSYSRKECAWLSHFYIESNKELKDGNLIIRFINGFAVKLEISKTSFENQQNRTAKLRTEYEDRRK
KQGNPCFKEVDKKEESRLKPAYESVYFVKEEEV

Sequences:

>Translated_193_residues
MENKVERYVENYVVNKNTMALLPVILSEKKIVTRVVEVQDSFFVFQKPLDIIERSCRKHGSSFLGRKEGTKELTHITHKA
PIAISPTDQLYFFPTYSYSRKECAWLSHFYIESNKELKDGNLIIRFINGFAVKLEISKTSFENQQNRTAKLRTEYEDRRK
KQGNPCFKEVDKKEESRLKPAYESVYFVKEEEV
>Mature_193_residues
MENKVERYVENYVVNKNTMALLPVILSEKKIVTRVVEVQDSFFVFQKPLDIIERSCRKHGSSFLGRKEGTKELTHITHKA
PIAISPTDQLYFFPTYSYSRKECAWLSHFYIESNKELKDGNLIIRFINGFAVKLEISKTSFENQQNRTAKLRTEYEDRRK
KQGNPCFKEVDKKEESRLKPAYESVYFVKEEEV

Specific function: Intermediate regulatory gene required for the expression of the late competence genes comC, comE, comG and the bdbDC operon. Receives signals from SrfA, and possibly other regulatory COM genes, and transduces these signals to the late COM genes [H]

COG id: COG4903

COG function: function code K; Genetic competence transcription factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010461 [H]

Pfam domain/function: PF06338 ComK [H]

EC number: NA

Molecular weight: Translated: 22760; Mature: 22760

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENKVERYVENYVVNKNTMALLPVILSEKKIVTRVVEVQDSFFVFQKPLDIIERSCRKHG
CCHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHC
SSFLGRKEGTKELTHITHKAPIAISPTDQLYFFPTYSYSRKECAWLSHFYIESNKELKDG
HHHHCCCCCHHHHHHHHCCCCEEECCCCCEEEEECCCCCCHHHHHHHHEEECCCCCCCCC
NLIIRFINGFAVKLEISKTSFENQQNRTAKLRTEYEDRRKKQGNPCFKEVDKKEESRLKP
CEEEEEECCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHCCC
AYESVYFVKEEEV
HHHHEEEEEECCC
>Mature Secondary Structure
MENKVERYVENYVVNKNTMALLPVILSEKKIVTRVVEVQDSFFVFQKPLDIIERSCRKHG
CCHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHC
SSFLGRKEGTKELTHITHKAPIAISPTDQLYFFPTYSYSRKECAWLSHFYIESNKELKDG
HHHHCCCCCHHHHHHHHCCCCEEECCCCCEEEEECCCCCCHHHHHHHHEEECCCCCCCCC
NLIIRFINGFAVKLEISKTSFENQQNRTAKLRTEYEDRRKKQGNPCFKEVDKKEESRLKP
CEEEEEECCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHCCC
AYESVYFVKEEEV
HHHHEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8196543; 9579061; 9384377; 7783616; 11744713 [H]