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The map label for this gene is ina [H]

Identifier: 52144052

GI number: 52144052

Start: 1275798

End: 1278188

Strand: Direct

Name: ina [H]

Synonym: BCZK1177

Alternate gene names: 52144052

Gene position: 1275798-1278188 (Clockwise)

Preceding gene: 52144054

Following gene: 52144051

Centisome position: 24.07

GC content: 39.36

Gene sequence:

>2391_bases
ATGAACAAGAAACCGTTCAAAGTTTTATCATCAATCGCTTTGACAGCTGTATTAGGCCTTTCATTCGGAGCGGGTGGCCA
GTCTGCATATGCTGAAACGCCTGTGAATAAGACAGCTACGAGTCCAGTTGATGATCATTTAATTCCGGAAGAACGTTTAG
CAGATGCGCTAAAAAAACGCGGGGTAATTGATTCGAAGGCTTCAGAGACAGAAACAAAGAAAGCTGTCGAAAAATACGTA
GAGAACAAAAAGGGTGAAAATCCTGGGAAAGAAGTATCAAATGGGGATCCACTTACGAAAGAAGCATCTGACTTTATAAA
GAAAGTGAAAGATGCGAAAGCAGATACGAAAGAAAAGTTAGACAAACCTGCAACAGGAACACCAGCAGCGACAGGACCAG
TTAAAGGTGGTCTAAATGGTAAAGTACCAACATCTCCGGCAAAGCAAAAAGCGTATAACGGTGATGTTCGTAAAGATAAA
GTACTCGTTTTACTTGTAGAGTACGCTGACTTTAAACATAACAATATCGATAAAGAACCTGGTTATATGTATTCGGAAGA
CTTTAACAAAGAACATTATGAAAAAATGTTATTCGGTAATGAGCCATTCACATTAGATGACGGAAGTAAAATCGAAACGT
TTAAACAATATTATGAAGAGCAATCTGGCGGTAGTTATACAGTAGACGGAACAGTTACAAAATGGTTAACAGTTCCTGGT
AAAGCTGCTGATTACGGTGCAGATGCTGCGAGCGGTGGTCATGATAATAAAGGGCCAAAAGGACCTCGTGATTTAGTAAA
AGATGCATTAAAAGCAGCTGTAGATAGCGGCATTGATTTATCAGAGTTTGACCAGTTCGATCAATACGATGTAAATGGTG
ATGGAAATCAAAATCAACCGGACGGTTTAATCGATCACTTAATGATTATTCATGCGGGTGTTGGACAAGAAGCAGGTGGT
GGTAAATTAGGTGATGATGCAATCTGGTCACATCGCTGGACTGTTGGACCAAAGCCATTCCCAATTGAAGGCACGCAAGC
AAAAGTTCCATATTGGGGCGGAAAGATTGCAGCATTTGACTACACAATTGAACCAGAAGATGGAGCGGTTGGTGTATTCG
CACATGAATATGGTCATGATTTAGGCCTTCCGGATGAGTACGATACACAATATAGCGGTCAAGGTGAGCCAATTGAAGCT
TGGTCTGTTATGAGTGGCGGAAGCTGGGCTGGTAAAATTGCAGGAACAACGCCAACGAGTTTCTCACCGCAAAATAAAGA
GTTTTTCCAAAAAACAATCGGTGGTAACTGGGCAAATATCGTAGAAGTAGATTACGAGAAATTAAATAAAGGTATCGGTT
TAGCAACATATTTAGACCAAAGTGTTACGAAATCTAACCGCCCAGGTATGATTCGTGTTAACTTACCTGATAAAGATGTA
AAAACAATTGATCCTGCATTTGGAAAACAGTATTACTACAGCACAAAAGGTGACGATCTTCATACGAAGATGGAAACACC
ACTGTTCGATTTAACGAATGCAACTACTGCAAAATTTGATTTCAAATCATTATATGAAATCGAAGCAGAGTATGACTTCC
TTGAAGTACATGCTGTAACAGAAGATGGTCAACAAACGTTAATTGAAAGACTTGGTGAGAAAGCTAATAGTGGAAATGCA
GATTCGACAAATGGAAAATGGATTGACAAATCATATGATTTAAGCCAATTCAAAGGTAAGAAAGTAAAATTAACATTTGA
TTACATTACTGATGGTGGTTTAGCATTAAATGGATTTGCTCTTGATAATGCTTCATTAACAGTAGATGGTAAAGTAGTAT
TCTCTGATGATGCAGAAGGGACACCACAATTAAAGTTAGATGGTTTTGTTGTATCTAACGGAACTGAGAAGAAAAAACAT
AACTATTATGTAGAGTGGAGAAACTATGCTGGTGCAGATAACGCATTGAAATTTGCTCGTGGTCCAGTATTTAACACTGG
TATGGTTGTATGGTATGCGGACTCAGCTTACACAGATAACTGGGTTGGCGTACATCCAGGACACGGTTTCCTTGGTGTAG
TAGATTCTCATCCAGAAGCAATTGTAGGAACTTTAAATGGTAAACCGACAGTTAAGAGTAGTACACGATTCCAAATTGCT
GATGCGGCGTTCTCATTCGACAAAACACCAGCTTGGAAAGTTGTATCTCCAACGCGTGGAACATTTACGTATGATGGCTT
AGCGGGTGTACCGAAGTTTGATGATTCAAAAACGTATATTAATCAACAGATTCCAGATGCAGGACGTATTTTACCGAATC
TTGGCCTGAAGTTTGAAGTAGTAGGACAAGCTGATGATAATTCTGCAGGTGCTGTTCGTTTATATCGTTAA

Upstream 100 bases:

>100_bases
TAAAAACATTACATAATATGACTAAATATTGAAAAAATATTGAATTTTTAATAAAATTCAATTTGTAATACATATTATTT
ATTAGGGGAGGAAATAAGGG

Downstream 100 bases:

>100_bases
TACAGTAAAACTACCGAGAGATTTTCTTTCGGTAGTTTTTTTGTGAGCAATGAATTTTATATGTAAGAAGAAATTATATA
TAATGTAATTTTATGAATAG

Product: immune inhibitor A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 796; Mature: 796

Protein sequence:

>796_residues
MNKKPFKVLSSIALTAVLGLSFGAGGQSAYAETPVNKTATSPVDDHLIPEERLADALKKRGVIDSKASETETKKAVEKYV
ENKKGENPGKEVSNGDPLTKEASDFIKKVKDAKADTKEKLDKPATGTPAATGPVKGGLNGKVPTSPAKQKAYNGDVRKDK
VLVLLVEYADFKHNNIDKEPGYMYSEDFNKEHYEKMLFGNEPFTLDDGSKIETFKQYYEEQSGGSYTVDGTVTKWLTVPG
KAADYGADAASGGHDNKGPKGPRDLVKDALKAAVDSGIDLSEFDQFDQYDVNGDGNQNQPDGLIDHLMIIHAGVGQEAGG
GKLGDDAIWSHRWTVGPKPFPIEGTQAKVPYWGGKIAAFDYTIEPEDGAVGVFAHEYGHDLGLPDEYDTQYSGQGEPIEA
WSVMSGGSWAGKIAGTTPTSFSPQNKEFFQKTIGGNWANIVEVDYEKLNKGIGLATYLDQSVTKSNRPGMIRVNLPDKDV
KTIDPAFGKQYYYSTKGDDLHTKMETPLFDLTNATTAKFDFKSLYEIEAEYDFLEVHAVTEDGQQTLIERLGEKANSGNA
DSTNGKWIDKSYDLSQFKGKKVKLTFDYITDGGLALNGFALDNASLTVDGKVVFSDDAEGTPQLKLDGFVVSNGTEKKKH
NYYVEWRNYAGADNALKFARGPVFNTGMVVWYADSAYTDNWVGVHPGHGFLGVVDSHPEAIVGTLNGKPTVKSSTRFQIA
DAAFSFDKTPAWKVVSPTRGTFTYDGLAGVPKFDDSKTYINQQIPDAGRILPNLGLKFEVVGQADDNSAGAVRLYR

Sequences:

>Translated_796_residues
MNKKPFKVLSSIALTAVLGLSFGAGGQSAYAETPVNKTATSPVDDHLIPEERLADALKKRGVIDSKASETETKKAVEKYV
ENKKGENPGKEVSNGDPLTKEASDFIKKVKDAKADTKEKLDKPATGTPAATGPVKGGLNGKVPTSPAKQKAYNGDVRKDK
VLVLLVEYADFKHNNIDKEPGYMYSEDFNKEHYEKMLFGNEPFTLDDGSKIETFKQYYEEQSGGSYTVDGTVTKWLTVPG
KAADYGADAASGGHDNKGPKGPRDLVKDALKAAVDSGIDLSEFDQFDQYDVNGDGNQNQPDGLIDHLMIIHAGVGQEAGG
GKLGDDAIWSHRWTVGPKPFPIEGTQAKVPYWGGKIAAFDYTIEPEDGAVGVFAHEYGHDLGLPDEYDTQYSGQGEPIEA
WSVMSGGSWAGKIAGTTPTSFSPQNKEFFQKTIGGNWANIVEVDYEKLNKGIGLATYLDQSVTKSNRPGMIRVNLPDKDV
KTIDPAFGKQYYYSTKGDDLHTKMETPLFDLTNATTAKFDFKSLYEIEAEYDFLEVHAVTEDGQQTLIERLGEKANSGNA
DSTNGKWIDKSYDLSQFKGKKVKLTFDYITDGGLALNGFALDNASLTVDGKVVFSDDAEGTPQLKLDGFVVSNGTEKKKH
NYYVEWRNYAGADNALKFARGPVFNTGMVVWYADSAYTDNWVGVHPGHGFLGVVDSHPEAIVGTLNGKPTVKSSTRFQIA
DAAFSFDKTPAWKVVSPTRGTFTYDGLAGVPKFDDSKTYINQQIPDAGRILPNLGLKFEVVGQADDNSAGAVRLYR
>Mature_796_residues
MNKKPFKVLSSIALTAVLGLSFGAGGQSAYAETPVNKTATSPVDDHLIPEERLADALKKRGVIDSKASETETKKAVEKYV
ENKKGENPGKEVSNGDPLTKEASDFIKKVKDAKADTKEKLDKPATGTPAATGPVKGGLNGKVPTSPAKQKAYNGDVRKDK
VLVLLVEYADFKHNNIDKEPGYMYSEDFNKEHYEKMLFGNEPFTLDDGSKIETFKQYYEEQSGGSYTVDGTVTKWLTVPG
KAADYGADAASGGHDNKGPKGPRDLVKDALKAAVDSGIDLSEFDQFDQYDVNGDGNQNQPDGLIDHLMIIHAGVGQEAGG
GKLGDDAIWSHRWTVGPKPFPIEGTQAKVPYWGGKIAAFDYTIEPEDGAVGVFAHEYGHDLGLPDEYDTQYSGQGEPIEA
WSVMSGGSWAGKIAGTTPTSFSPQNKEFFQKTIGGNWANIVEVDYEKLNKGIGLATYLDQSVTKSNRPGMIRVNLPDKDV
KTIDPAFGKQYYYSTKGDDLHTKMETPLFDLTNATTAKFDFKSLYEIEAEYDFLEVHAVTEDGQQTLIERLGEKANSGNA
DSTNGKWIDKSYDLSQFKGKKVKLTFDYITDGGLALNGFALDNASLTVDGKVVFSDDAEGTPQLKLDGFVVSNGTEKKKH
NYYVEWRNYAGADNALKFARGPVFNTGMVVWYADSAYTDNWVGVHPGHGFLGVVDSHPEAIVGTLNGKPTVKSSTRFQIA
DAAFSFDKTPAWKVVSPTRGTFTYDGLAGVPKFDDSKTYINQQIPDAGRILPNLGLKFEVVGQADDNSAGAVRLYR

Specific function: Neutral metalloprotease that is secreted to degrade antibacterial proteins produced by the insect host for its defense (attacins and cecropins). Probably degrades some unknown crucial protein(s) too, since it is toxic when injected to insect larvae [H]

COG id: COG4412

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M6 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012300
- InterPro:   IPR008757 [H]

Pfam domain/function: PF05547 Peptidase_M6 [H]

EC number: NA

Molecular weight: Translated: 86623; Mature: 86623

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKPFKVLSSIALTAVLGLSFGAGGQSAYAETPVNKTATSPVDDHLIPEERLADALKKR
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHC
GVIDSKASETETKKAVEKYVENKKGENPGKEVSNGDPLTKEASDFIKKVKDAKADTKEKL
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHH
DKPATGTPAATGPVKGGLNGKVPTSPAKQKAYNGDVRKDKVLVLLVEYADFKHNNIDKEP
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCEEEEEEEEECCCCCCCCCCCC
GYMYSEDFNKEHYEKMLFGNEPFTLDDGSKIETFKQYYEEQSGGSYTVDGTVTKWLTVPG
CCCCCCCCCHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHCCCCCEEECCCEEEEEECCC
KAADYGADAASGGHDNKGPKGPRDLVKDALKAAVDSGIDLSEFDQFDQYDVNGDGNQNQP
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCC
DGLIDHLMIIHAGVGQEAGGGKLGDDAIWSHRWTVGPKPFPIEGTQAKVPYWGGKIAAFD
HHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCEECCCCCCCCCCCCCEECCCCCCEEEEEE
YTIEPEDGAVGVFAHEYGHDLGLPDEYDTQYSGQGEPIEAWSVMSGGSWAGKIAGTTPTS
EEECCCCCEEEEEEHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCEECCCCCCC
FSPQNKEFFQKTIGGNWANIVEVDYEKLNKGIGLATYLDQSVTKSNRPGMIRVNLPDKDV
CCCCCHHHHHHHHCCCEEEEEEECHHHHHCCCCCHHHHHHHHHCCCCCCEEEEECCCCCC
KTIDPAFGKQYYYSTKGDDLHTKMETPLFDLTNATTAKFDFKSLYEIEAEYDFLEVHAVT
CCCCHHHCCCEEEECCCCCCHHHHCCCEEECCCCCEEEECHHHHHEECCCCCEEEEEEEC
EDGQQTLIERLGEKANSGNADSTNGKWIDKSYDLSQFKGKKVKLTFDYITDGGLALNGFA
CCHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCHHHHCCCEEEEEEEEECCCCEEEEEEE
LDNASLTVDGKVVFSDDAEGTPQLKLDGFVVSNGTEKKKHNYYVEWRNYAGADNALKFAR
ECCCEEEECCEEEECCCCCCCCCEEECCEEEECCCCCCCCCEEEEECCCCCCCHHHHHHC
GPVFNTGMVVWYADSAYTDNWVGVHPGHGFLGVVDSHPEAIVGTLNGKPTVKSSTRFQIA
CCCCCCCEEEEEECCCCCCCEEEECCCCCEEEEECCCCCEEEEECCCCCCCCCCCEEEEE
DAAFSFDKTPAWKVVSPTRGTFTYDGLAGVPKFDDSKTYINQQIPDAGRILPNLGLKFEV
HHHHCCCCCCCEEEECCCCCCEEECCCCCCCCCCCCHHHHHHCCCCHHHHHCCCCCEEEE
VGQADDNSAGAVRLYR
EECCCCCCCCEEEEEC
>Mature Secondary Structure
MNKKPFKVLSSIALTAVLGLSFGAGGQSAYAETPVNKTATSPVDDHLIPEERLADALKKR
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHC
GVIDSKASETETKKAVEKYVENKKGENPGKEVSNGDPLTKEASDFIKKVKDAKADTKEKL
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHH
DKPATGTPAATGPVKGGLNGKVPTSPAKQKAYNGDVRKDKVLVLLVEYADFKHNNIDKEP
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCEEEEEEEEECCCCCCCCCCCC
GYMYSEDFNKEHYEKMLFGNEPFTLDDGSKIETFKQYYEEQSGGSYTVDGTVTKWLTVPG
CCCCCCCCCHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHCCCCCEEECCCEEEEEECCC
KAADYGADAASGGHDNKGPKGPRDLVKDALKAAVDSGIDLSEFDQFDQYDVNGDGNQNQP
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCC
DGLIDHLMIIHAGVGQEAGGGKLGDDAIWSHRWTVGPKPFPIEGTQAKVPYWGGKIAAFD
HHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCEECCCCCCCCCCCCCEECCCCCCEEEEEE
YTIEPEDGAVGVFAHEYGHDLGLPDEYDTQYSGQGEPIEAWSVMSGGSWAGKIAGTTPTS
EEECCCCCEEEEEEHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCEECCCCCCC
FSPQNKEFFQKTIGGNWANIVEVDYEKLNKGIGLATYLDQSVTKSNRPGMIRVNLPDKDV
CCCCCHHHHHHHHCCCEEEEEEECHHHHHCCCCCHHHHHHHHHCCCCCCEEEEECCCCCC
KTIDPAFGKQYYYSTKGDDLHTKMETPLFDLTNATTAKFDFKSLYEIEAEYDFLEVHAVT
CCCCHHHCCCEEEECCCCCCHHHHCCCEEECCCCCEEEECHHHHHEECCCCCEEEEEEEC
EDGQQTLIERLGEKANSGNADSTNGKWIDKSYDLSQFKGKKVKLTFDYITDGGLALNGFA
CCHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCHHHHCCCEEEEEEEEECCCCEEEEEEE
LDNASLTVDGKVVFSDDAEGTPQLKLDGFVVSNGTEKKKHNYYVEWRNYAGADNALKFAR
ECCCEEEECCEEEECCCCCCCCCEEECCEEEECCCCCCCCCEEEEECCCCCCCHHHHHHC
GPVFNTGMVVWYADSAYTDNWVGVHPGHGFLGVVDSHPEAIVGTLNGKPTVKSSTRFQIA
CCCCCCCEEEEEECCCCCCCEEEECCCCCEEEEECCCCCEEEEECCCCCCCCCCCEEEEE
DAAFSFDKTPAWKVVSPTRGTFTYDGLAGVPKFDDSKTYINQQIPDAGRILPNLGLKFEV
HHHHCCCCCCCEEEECCCCCCEEECCCCCCCCCCCCHHHHHHCCCCHHHHHCCCCCEEEE
VGQADDNSAGAVRLYR
EECCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2089225; 6421577 [H]