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The map label for this gene is inlA [H]

Identifier: 52144007

GI number: 52144007

Start: 1322497

End: 1324815

Strand: Direct

Name: inlA [H]

Synonym: BCZK1222

Alternate gene names: 52144007

Gene position: 1322497-1324815 (Clockwise)

Preceding gene: 52144008

Following gene: 52144006

Centisome position: 24.95

GC content: 31.61

Gene sequence:

>2319_bases
ATGATAGGGGATATTATTTTGAAAAAAAAATATATGAAGGCGCTAGTAGTAGCGACAACATTAGCAATTCCATTTGCTGC
ATACTCTACTCCAGCATTAGCAGCACTAAAAGCTGAAGCAAATCAGTCGGTGGTAGCAGCTAGTGAACGTACATACGCTA
CTGAGATTAAAATATATAAGGACCAAAAAGACGAGCCATCTATGGTTTCTCAATATATAAAAGATCCTAAAGTAACGATT
GCAGCTGGCAAAAAAATTGTTACTGTAACAATGCAGGATAGCGATTATTTTCAATATCTTAGAATAGAAGATAAAAATCA
ACCAGATGTATTTCATGATGTGAAAGTTTTGTCAGAAGATAAGAGGAAGAATGGAACGAAAGTAGTTCAATTTGAAATTG
ACGAGTTTGAGAAGAAGCACAATATGCAAATGCATATACTTATTCCGGCTATTGGATATGATCACAAATATCAAGTTCAA
TTTGAAATTAAAGATCCAACTGTAGGTAACAAAGAAACAGAGAAACCAGATGATAACTCTAATTCAGGCAATACGGAAAC
GGATCATCCAGTTGATAATCAAAATATGATAACAGATAACAAATTAAGAGAACTTGTGAATAAAAAAGTATTTAATAGAA
AAGATTTAAATACACCAATTACGAAAGAAGAGTTATTACAAGTAAAGAATTTGTTTTTAAATACGAATGAGATTCTCGAT
TATAGTGCATTAAAATATATGCCAAATTTGAAATCTTTAACAGTTGCGAATGCGAAGATAAAAGATCCGTCGTTCTTTGC
GAACTTAAAGCAATTAAATCATTTAGCATTGCGTGGTAATGAATTTTCAGATGTAACACCACTTGTTAAGATGGATCATT
TAGATTCTCTTGATTTAAGTAATAATAAAATTACAAACGTTGCACCACTAATTGAAATGAAAAATGTAAAAAGTTTATAT
CTATCAGGTAACCAAATAGAAGATGTAACAGTATTAGCGAAAATGGAACAACTAGATTATTTAAATTTAGCAAATAATAA
AATTACGAATGTTGCTCCATTAAGCGCGTTAAAAAATGTAACATACTTGACTTTAGCAGGTAATCAAATTGAAGATATTA
AACCGTTATATTCATTACCTTTAAAAGACTTAGTATTAACGCGTAATAAAGTAAAAGATTTATCCGGCATTGAGCAAATG
AAGCAATTAGAAGAATTGTGGATCGGGAAAAATGAAATAAAAGATATTACCCCTCTAAGTAAGATGACACAATTGAAAGA
ATTACACTTACCTAACAATGAGTTAACAGATATTACTCCATTATCAAGTCTAGTAAACTTACAAAAGCTTGATTTAGAAG
CAAATTATATTTCAGACTTAACACCAGCTAGCAATTTGAAAAAGTTAGTATTCTTAAGTTTTGTTGCAAATGAAATTCGT
GATGTTCGACCAGTAATAGAACTAAGTAAGAAAGCTTATATTAATGTTCAAAACCAAAAAGTCTTTTTAGAGGATACAGA
AGTAAATGAAGAAGTAAAAGTACCTATATACGAAAAAGACGGTAAAATCTCTACAAAAATTCGTTTGAAGAGCGAAGGTG
GTACGTATAGTAATGATGCAGTTAAGTGGAGTACACCAGGAGAGAAAGTATATGAATTTGGTATAAAAGATCCATTTGCG
GATACAGGAATCTTCTTCACAGGATCTGTAATTCAAAATGTGGTAGAAAGCAAAGCGGATAACACTTCTAAAGAAGGTAA
TAATTCTAGAGAAGATGAAAAAGTAGAAGTAGTAGAATTTAAAGATGTACCAAAAGGACATTGGTCAGAAGAAGCAATTA
ACTATTTAGCGAAAGAAAATATTTTCAAGGGATATGGAAATGGACAATTTGGATTTGGGGATAGTATTACTCGTGGACAA
GTTGCGTCTTTAGTACAAAGATATTTGAAATTACAAAATAAAGCAGAGCAGAAAGAGAGATTTACAGATACGAAAGGGCA
TATGTTTGAGCAAGATATTGCTACAGTTGCGCAAGCTGGAATTATGCAAGGAGATGGTACTGGGGAGTTTCGTCCAGATG
GAGTATTAACTCGATACGAAATGTCTGTAGTATTATATAAAGTATTTCAGTTAAAAGAAGATGGAAATAATAAAGTGAAC
TTTAAAGATGTACCAACTGGTCATTGGGCAGAAGGGTATGTGAAAGCGTTAGTGGATAATAACATATCAAAAGGTGATGG
AAAAGAACACTTTTTAGGTGATGATTTTGTAACACGTGAACAATATGCACAGTTTTTATATAACGCAATAACGAAATAA

Upstream 100 bases:

>100_bases
ATATAAATTTAATGTAATATTCTCATTGACAATGATAATGATATTCATTATCATTTATTTGTAGTTAAGTGATAAGGGTT
ATCAATTATAAAAATTATAT

Downstream 100 bases:

>100_bases
AAGATGAGAAAATACGTTATTCTTTCATTGGAAAAGAATAACGTATTTTTTATGTATAAAATGAACTAGTCAATATACAG
GAGTATAGACATATGAATGG

Product: internalin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 772; Mature: 772

Protein sequence:

>772_residues
MIGDIILKKKYMKALVVATTLAIPFAAYSTPALAALKAEANQSVVAASERTYATEIKIYKDQKDEPSMVSQYIKDPKVTI
AAGKKIVTVTMQDSDYFQYLRIEDKNQPDVFHDVKVLSEDKRKNGTKVVQFEIDEFEKKHNMQMHILIPAIGYDHKYQVQ
FEIKDPTVGNKETEKPDDNSNSGNTETDHPVDNQNMITDNKLRELVNKKVFNRKDLNTPITKEELLQVKNLFLNTNEILD
YSALKYMPNLKSLTVANAKIKDPSFFANLKQLNHLALRGNEFSDVTPLVKMDHLDSLDLSNNKITNVAPLIEMKNVKSLY
LSGNQIEDVTVLAKMEQLDYLNLANNKITNVAPLSALKNVTYLTLAGNQIEDIKPLYSLPLKDLVLTRNKVKDLSGIEQM
KQLEELWIGKNEIKDITPLSKMTQLKELHLPNNELTDITPLSSLVNLQKLDLEANYISDLTPASNLKKLVFLSFVANEIR
DVRPVIELSKKAYINVQNQKVFLEDTEVNEEVKVPIYEKDGKISTKIRLKSEGGTYSNDAVKWSTPGEKVYEFGIKDPFA
DTGIFFTGSVIQNVVESKADNTSKEGNNSREDEKVEVVEFKDVPKGHWSEEAINYLAKENIFKGYGNGQFGFGDSITRGQ
VASLVQRYLKLQNKAEQKERFTDTKGHMFEQDIATVAQAGIMQGDGTGEFRPDGVLTRYEMSVVLYKVFQLKEDGNNKVN
FKDVPTGHWAEGYVKALVDNNISKGDGKEHFLGDDFVTREQYAQFLYNAITK

Sequences:

>Translated_772_residues
MIGDIILKKKYMKALVVATTLAIPFAAYSTPALAALKAEANQSVVAASERTYATEIKIYKDQKDEPSMVSQYIKDPKVTI
AAGKKIVTVTMQDSDYFQYLRIEDKNQPDVFHDVKVLSEDKRKNGTKVVQFEIDEFEKKHNMQMHILIPAIGYDHKYQVQ
FEIKDPTVGNKETEKPDDNSNSGNTETDHPVDNQNMITDNKLRELVNKKVFNRKDLNTPITKEELLQVKNLFLNTNEILD
YSALKYMPNLKSLTVANAKIKDPSFFANLKQLNHLALRGNEFSDVTPLVKMDHLDSLDLSNNKITNVAPLIEMKNVKSLY
LSGNQIEDVTVLAKMEQLDYLNLANNKITNVAPLSALKNVTYLTLAGNQIEDIKPLYSLPLKDLVLTRNKVKDLSGIEQM
KQLEELWIGKNEIKDITPLSKMTQLKELHLPNNELTDITPLSSLVNLQKLDLEANYISDLTPASNLKKLVFLSFVANEIR
DVRPVIELSKKAYINVQNQKVFLEDTEVNEEVKVPIYEKDGKISTKIRLKSEGGTYSNDAVKWSTPGEKVYEFGIKDPFA
DTGIFFTGSVIQNVVESKADNTSKEGNNSREDEKVEVVEFKDVPKGHWSEEAINYLAKENIFKGYGNGQFGFGDSITRGQ
VASLVQRYLKLQNKAEQKERFTDTKGHMFEQDIATVAQAGIMQGDGTGEFRPDGVLTRYEMSVVLYKVFQLKEDGNNKVN
FKDVPTGHWAEGYVKALVDNNISKGDGKEHFLGDDFVTREQYAQFLYNAITK
>Mature_772_residues
MIGDIILKKKYMKALVVATTLAIPFAAYSTPALAALKAEANQSVVAASERTYATEIKIYKDQKDEPSMVSQYIKDPKVTI
AAGKKIVTVTMQDSDYFQYLRIEDKNQPDVFHDVKVLSEDKRKNGTKVVQFEIDEFEKKHNMQMHILIPAIGYDHKYQVQ
FEIKDPTVGNKETEKPDDNSNSGNTETDHPVDNQNMITDNKLRELVNKKVFNRKDLNTPITKEELLQVKNLFLNTNEILD
YSALKYMPNLKSLTVANAKIKDPSFFANLKQLNHLALRGNEFSDVTPLVKMDHLDSLDLSNNKITNVAPLIEMKNVKSLY
LSGNQIEDVTVLAKMEQLDYLNLANNKITNVAPLSALKNVTYLTLAGNQIEDIKPLYSLPLKDLVLTRNKVKDLSGIEQM
KQLEELWIGKNEIKDITPLSKMTQLKELHLPNNELTDITPLSSLVNLQKLDLEANYISDLTPASNLKKLVFLSFVANEIR
DVRPVIELSKKAYINVQNQKVFLEDTEVNEEVKVPIYEKDGKISTKIRLKSEGGTYSNDAVKWSTPGEKVYEFGIKDPFA
DTGIFFTGSVIQNVVESKADNTSKEGNNSREDEKVEVVEFKDVPKGHWSEEAINYLAKENIFKGYGNGQFGFGDSITRGQ
VASLVQRYLKLQNKAEQKERFTDTKGHMFEQDIATVAQAGIMQGDGTGEFRPDGVLTRYEMSVVLYKVFQLKEDGNNKVN
FKDVPTGHWAEGYVKALVDNNISKGDGKEHFLGDDFVTREQYAQFLYNAITK

Specific function: Mediates the entry of Listeria monocytogenes into cells [H]

COG id: COG4886

COG function: function code S; Leucine-rich repeat (LRR) protein

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 14 LRR (leucine-rich) repeats [H]

Homologues:

Organism=Homo sapiens, GI21389483, Length=210, Percent_Identity=30, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI4506013, Length=237, Percent_Identity=30.379746835443, Blast_Score=83, Evalue=1e-15,
Organism=Homo sapiens, GI21361633, Length=249, Percent_Identity=28.9156626506024, Blast_Score=70, Evalue=9e-12,
Organism=Homo sapiens, GI55743114, Length=142, Percent_Identity=34.5070422535211, Blast_Score=70, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17536161, Length=201, Percent_Identity=32.3383084577114, Blast_Score=88, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17554124, Length=245, Percent_Identity=28.1632653061224, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17531555, Length=220, Percent_Identity=28.1818181818182, Blast_Score=79, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI71984630, Length=296, Percent_Identity=27.027027027027, Blast_Score=74, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17542472, Length=276, Percent_Identity=30.0724637681159, Blast_Score=66, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322655, Length=227, Percent_Identity=29.5154185022026, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI21358617, Length=211, Percent_Identity=28.436018957346, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24658034, Length=185, Percent_Identity=28.6486486486486, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24662159, Length=256, Percent_Identity=30.46875, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014755
- InterPro:   IPR019948
- InterPro:   IPR014756
- InterPro:   IPR001611
- InterPro:   IPR013378
- InterPro:   IPR019931
- InterPro:   IPR012569
- InterPro:   IPR001899 [H]

Pfam domain/function: PF09479 Flg_new; PF00746 Gram_pos_anchor; PF00560 LRR_1; PF08191 LRR_adjacent [H]

EC number: NA

Molecular weight: Translated: 87295; Mature: 87295

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS50978 NEAT ; PS01072 SLH_DOMAIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGDIILKKKYMKALVVATTLAIPFAAYSTPALAALKAEANQSVVAASERTYATEIKIYK
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEECCCEEEEEEEEEE
DQKDEPSMVSQYIKDPKVTIAAGKKIVTVTMQDSDYFQYLRIEDKNQPDVFHDVKVLSED
CCCCCHHHHHHHHCCCCEEEECCCEEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHH
KRKNGTKVVQFEIDEFEKKHNMQMHILIPAIGYDHKYQVQFEIKDPTVGNKETEKPDDNS
HCCCCCEEEEEEHHHHHHHHCCEEEEEEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCC
NSGNTETDHPVDNQNMITDNKLRELVNKKVFNRKDLNTPITKEELLQVKNLFLNTNEILD
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHHH
YSALKYMPNLKSLTVANAKIKDPSFFANLKQLNHLALRGNEFSDVTPLVKMDHLDSLDLS
HHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCC
NNKITNVAPLIEMKNVKSLYLSGNQIEDVTVLAKMEQLDYLNLANNKITNVAPLSALKNV
CCCCCCHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHCHHCCCCCCCCCCHHHHHHCCC
TYLTLAGNQIEDIKPLYSLPLKDLVLTRNKVKDLSGIEQMKQLEELWIGKNEIKDITPLS
EEEEEECCCHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHH
KMTQLKELHLPNNELTDITPLSSLVNLQKLDLEANYISDLTPASNLKKLVFLSFVANEIR
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHH
DVRPVIELSKKAYINVQNQKVFLEDTEVNEEVKVPIYEKDGKISTKIRLKSEGGTYSNDA
HHHHHHHHCCCEEEEEECCEEEEECCCCCCEEEEEEEECCCCEEEEEEEECCCCCCCCCC
VKWSTPGEKVYEFGIKDPFADTGIFFTGSVIQNVVESKADNTSKEGNNSREDEKVEVVEF
EEECCCCHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEE
KDVPKGHWSEEAINYLAKENIFKGYGNGQFGFGDSITRGQVASLVQRYLKLQNKAEQKER
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
FTDTKGHMFEQDIATVAQAGIMQGDGTGEFRPDGVLTRYEMSVVLYKVFQLKEDGNNKVN
HCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCEEE
FKDVPTGHWAEGYVKALVDNNISKGDGKEHFLGDDFVTREQYAQFLYNAITK
EEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIGDIILKKKYMKALVVATTLAIPFAAYSTPALAALKAEANQSVVAASERTYATEIKIYK
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEECCCEEEEEEEEEE
DQKDEPSMVSQYIKDPKVTIAAGKKIVTVTMQDSDYFQYLRIEDKNQPDVFHDVKVLSED
CCCCCHHHHHHHHCCCCEEEECCCEEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHH
KRKNGTKVVQFEIDEFEKKHNMQMHILIPAIGYDHKYQVQFEIKDPTVGNKETEKPDDNS
HCCCCCEEEEEEHHHHHHHHCCEEEEEEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCC
NSGNTETDHPVDNQNMITDNKLRELVNKKVFNRKDLNTPITKEELLQVKNLFLNTNEILD
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHHH
YSALKYMPNLKSLTVANAKIKDPSFFANLKQLNHLALRGNEFSDVTPLVKMDHLDSLDLS
HHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCC
NNKITNVAPLIEMKNVKSLYLSGNQIEDVTVLAKMEQLDYLNLANNKITNVAPLSALKNV
CCCCCCHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHCHHCCCCCCCCCCHHHHHHCCC
TYLTLAGNQIEDIKPLYSLPLKDLVLTRNKVKDLSGIEQMKQLEELWIGKNEIKDITPLS
EEEEEECCCHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHH
KMTQLKELHLPNNELTDITPLSSLVNLQKLDLEANYISDLTPASNLKKLVFLSFVANEIR
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHH
DVRPVIELSKKAYINVQNQKVFLEDTEVNEEVKVPIYEKDGKISTKIRLKSEGGTYSNDA
HHHHHHHHCCCEEEEEECCEEEEECCCCCCEEEEEEEECCCCEEEEEEEECCCCCCCCCC
VKWSTPGEKVYEFGIKDPFADTGIFFTGSVIQNVVESKADNTSKEGNNSREDEKVEVVEF
EEECCCCHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEE
KDVPKGHWSEEAINYLAKENIFKGYGNGQFGFGDSITRGQVASLVQRYLKLQNKAEQKER
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
FTDTKGHMFEQDIATVAQAGIMQGDGTGEFRPDGVLTRYEMSVVLYKVFQLKEDGNNKVN
HCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCEEE
FKDVPTGHWAEGYVKALVDNNISKGDGKEHFLGDDFVTREQYAQFLYNAITK
EEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9541569 [H]