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The map label for this gene is ktrB [H]

Identifier: 52143954

GI number: 52143954

Start: 1369801

End: 1371144

Strand: Direct

Name: ktrB [H]

Synonym: BCZK1275

Alternate gene names: 52143954

Gene position: 1369801-1371144 (Clockwise)

Preceding gene: 52143955

Following gene: 52143950

Centisome position: 25.84

GC content: 33.78

Gene sequence:

>1344_bases
ATGGAAGTAACAAAAAGACAAAGGCTGTATAATCGTTTTATACGATTAAATCCACCACAAATATTAGCATTAGGTTTTTT
CTGCTTAATTGTGGTTGGCGGTTTGTTATTAAAGTTACCATTCGCAACGAAAGTACATATTAGTTGGGTAGATGCTTTCT
TTACGGCAACGTCAGCAGCAACTGTAACGGGATTGGGAGTAGTAGATACTGCAAGTACGTTTACGATGTTTGGTGAAATT
GTTATTATGTTTTTAATTCAAACAGGTGGTCTAGGTCTTATGACGATTGCCATTTTAATTGTTTGGGTATTAGGTAAAAA
AATTGGTTTACGCCATCGCTTATTAATTGGAGAGGCTTTTAATCAGACAAATATAGGTGGTCTCGTAAAATTAGTAAAAC
GTGTCTTTATATTTTCAATTTGTATTGAGTTTATTGGGGTTATCTTTTTATCGTTTCGCTTTATTCCAGAGTTTGGCTTT
GGAAAAGGGTTATATTATAGTATTTTCCATGTAATTGCATCCTATAATAATGCGGGATTTGCTCTATGGCCGGATAATTT
AACGAGGTATGTAGGCGATCCTATTATTAATATTGGGATTTGCTCTTTAATCGTAATAGGTGGTCTCGGATTTACCGTAT
TAATTGATATATGGTATAGCCGTAGTTTTCGAAAATTATCACTGCATTCAAAAATCATGATTGTTGGAACAGTAGCGCTA
AATGTAATAGCGATGATTGTGATTTTTATATTGGAGTATAATAATGTGAAGACGTTAGGGAATTTACCTTTAAATGAAAA
ATTATGGGCTTCTTTCTTCCAAGGTATTACTCCTCGTACTGCAGGATTTAATACAGTTGACTACGGAGGTATGGAAGAAT
CATCTATATTATTTACGATGGTTTTAATGTTTATTGGTGCAGGAAGTGTATCAACAGGTGGAGGGATTAAATTAACAACG
TTTGTTATTTTAGTTACATCTGTCCTTTCTTTCTTTAGAAAGAAAGAGGAAATTGTTTTATTCCAGCGCACGATCAAAAT
GTCGACAGTAACGAGAGCTTTAGCCATAGCTGTTGCCAGTCAAATTCTCATTTTTGCAGCAGTATTTGTATTAATGCTTA
CAGAAAACTTCAGTTTTATTCAGTTACTATTTGAAACAATTTCAGCATTTGGAACAGTAGGGTTAACGATGGGGATTACT
GCGAAGTTATCAGCGTTTGGAAAATGTATTATTATGTTTGTTATGTTTTGTGGATTAATCGGACCGTTAACACTTGTTTT
TTCTTTAGCACGACCAGCAAAACAAAAAATTAAATATCCATCAGAAGATGTATTTACAGGGTAA

Upstream 100 bases:

>100_bases
CTATATTATAAGAATATGAGGTTTATCCGACTATTTGAAGGCTCTTAAAAGCCTTTATTTATGAAGGAAAAGCTGCACTT
TATTAAGGGAGTTAGTGAAT

Downstream 100 bases:

>100_bases
GGTATCTCGCATAAGCGAGATACCTTTTTCTTTTTAAAAAAGGGAGAATAATAAACCGATAAGTGCTACTCGGAATAAAA
TTGCAATGAGTGCTGCAATT

Product: potassium/sodium uptake protein

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: K(+)-uptake protein ktrB [H]

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MEVTKRQRLYNRFIRLNPPQILALGFFCLIVVGGLLLKLPFATKVHISWVDAFFTATSAATVTGLGVVDTASTFTMFGEI
VIMFLIQTGGLGLMTIAILIVWVLGKKIGLRHRLLIGEAFNQTNIGGLVKLVKRVFIFSICIEFIGVIFLSFRFIPEFGF
GKGLYYSIFHVIASYNNAGFALWPDNLTRYVGDPIINIGICSLIVIGGLGFTVLIDIWYSRSFRKLSLHSKIMIVGTVAL
NVIAMIVIFILEYNNVKTLGNLPLNEKLWASFFQGITPRTAGFNTVDYGGMEESSILFTMVLMFIGAGSVSTGGGIKLTT
FVILVTSVLSFFRKKEEIVLFQRTIKMSTVTRALAIAVASQILIFAAVFVLMLTENFSFIQLLFETISAFGTVGLTMGIT
AKLSAFGKCIIMFVMFCGLIGPLTLVFSLARPAKQKIKYPSEDVFTG

Sequences:

>Translated_447_residues
MEVTKRQRLYNRFIRLNPPQILALGFFCLIVVGGLLLKLPFATKVHISWVDAFFTATSAATVTGLGVVDTASTFTMFGEI
VIMFLIQTGGLGLMTIAILIVWVLGKKIGLRHRLLIGEAFNQTNIGGLVKLVKRVFIFSICIEFIGVIFLSFRFIPEFGF
GKGLYYSIFHVIASYNNAGFALWPDNLTRYVGDPIINIGICSLIVIGGLGFTVLIDIWYSRSFRKLSLHSKIMIVGTVAL
NVIAMIVIFILEYNNVKTLGNLPLNEKLWASFFQGITPRTAGFNTVDYGGMEESSILFTMVLMFIGAGSVSTGGGIKLTT
FVILVTSVLSFFRKKEEIVLFQRTIKMSTVTRALAIAVASQILIFAAVFVLMLTENFSFIQLLFETISAFGTVGLTMGIT
AKLSAFGKCIIMFVMFCGLIGPLTLVFSLARPAKQKIKYPSEDVFTG
>Mature_447_residues
MEVTKRQRLYNRFIRLNPPQILALGFFCLIVVGGLLLKLPFATKVHISWVDAFFTATSAATVTGLGVVDTASTFTMFGEI
VIMFLIQTGGLGLMTIAILIVWVLGKKIGLRHRLLIGEAFNQTNIGGLVKLVKRVFIFSICIEFIGVIFLSFRFIPEFGF
GKGLYYSIFHVIASYNNAGFALWPDNLTRYVGDPIINIGICSLIVIGGLGFTVLIDIWYSRSFRKLSLHSKIMIVGTVAL
NVIAMIVIFILEYNNVKTLGNLPLNEKLWASFFQGITPRTAGFNTVDYGGMEESSILFTMVLMFIGAGSVSTGGGIKLTT
FVILVTSVLSFFRKKEEIVLFQRTIKMSTVTRALAIAVASQILIFAAVFVLMLTENFSFIQLLFETISAFGTVGLTMGIT
AKLSAFGKCIIMFVMFCGLIGPLTLVFSLARPAKQKIKYPSEDVFTG

Specific function: Integral membrane subunit of the KtrAB potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and KtrCD confer resistance to both suddenly imposed and prolonged osmotic stress [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family. Ktr (TC 2.A.38.4) subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 49221; Mature: 49221

Theoretical pI: Translated: 10.26; Mature: 10.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]