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The map label for this gene is yfiS [H]

Identifier: 52143736

GI number: 52143736

Start: 1589541

End: 1590755

Strand: Reverse

Name: yfiS [H]

Synonym: BCZK1498

Alternate gene names: 52143736

Gene position: 1590755-1589541 (Counterclockwise)

Preceding gene: 52143735

Following gene: 52143738

Centisome position: 30.01

GC content: 32.26

Gene sequence:

>1215_bases
ATGTCAGTTTCTTATAGAACACTTCTTAAAACAAATAAAAACTTCAACAAACTATTTTACGGACAAACATTAAGTGTACT
TGGAGATTGGTTTCATACAGTAGCTTTATTAACATTCGTCTATAGCATAACAGAATCTCCGTTTATGATTGCACTTACTT
TTATAAGTAAAGGTTTACCACAACTACTTCTTAGCCCTTTCATAGGCGGAGTGGTAGATCGTTTTTCTAAAAAGAATATT
ATGATTTTTACCGATATTACACGGGGAATTCTAGTCCTTACATACATACTCGCAAACTATAAAATTGAAATTATTTTCAT
TGCTAATATATGTTTATCTGTACTTTCTTGCTTATTTGAGCCTGCTAAACAAGCAACCTTAAAAAACATCGTACACGAAA
ATCATTTCGTAACTGCTAACTCTCTTTCTAGTACAATGAATGGTTTTATGTCTATTATGGGTGCTTCTTTAGGCGGTATA
ATTGCACAATCTTTACATATTGAGTTCGCTTTTTTAGTAAATAGCCTATCATACTTTATTTCGGCCTATTTTATTTATAA
TATGAGTATCCCTGCTCATGATACTTGTAACAAGAAAAAAGTATTTTTGACTGATATAAAAGATGGATATACATACATAT
TACAAACAAAAATCATTTTAACGTTAATTCTTGTCGGCATTTCATGGGGGCTTATTGGAGGTGCTTATCAGCTACTTCTA
ACGATCTATGCCGAAAAAATTTTCCACACGAACATTGGGATTTTATATACGGTTCAAGGGGCTGGGCTTATGATAGGAAG
CCTTCTCGTTAATCTTTATATATCCAATAATAAAGAAAAAATGAAAAAAGCATTTGGTTGGGCCTACTTCTTACAAGGCT
TTTTCTTTCTTGGATTCATTCTATCCAATCAACTTATTTTCGGTATTATTACATTACTATGTATGCGCATAGCAGGAGGA
ATCATCGTTCCACTTGATACGACATTACTTCAAGCTTACACGCACGAAAATATGATTGGTAAAGTTTTTTCCTTTCATTA
CTCAATTTACGGTTCGCTTATACAGTTATCTATGTTCATTACAGGATGGCTATTAGAAATCCTTTCTCCTCAAATGATTG
GTAGTTTACTAGCTACATGTTGTATATTTGTAAGTTTTATATGGCTTTACCTGTTTTATCGCGGGAAACTTAGTGAAGAA
TCTATTAGTACTTAA

Upstream 100 bases:

>100_bases
GCACAATTACCAGTTGGACTTCCTTCAGAAAAGAAAGTGTATTTAAGTGAATGGAAAAAACAAATTCAAGCATCATCATT
ACATAAGGATTGAGCTTTTT

Downstream 100 bases:

>100_bases
TAGCATGTTTATGTACAGGCTATTTTTATTTATGTCGAAATATAAAGGAAAAAGACGATTTATTTTCCTTACGTTCTAAT
TTTTTAGAATGTACAATGAA

Product: macrolide efflux protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MSVSYRTLLKTNKNFNKLFYGQTLSVLGDWFHTVALLTFVYSITESPFMIALTFISKGLPQLLLSPFIGGVVDRFSKKNI
MIFTDITRGILVLTYILANYKIEIIFIANICLSVLSCLFEPAKQATLKNIVHENHFVTANSLSSTMNGFMSIMGASLGGI
IAQSLHIEFAFLVNSLSYFISAYFIYNMSIPAHDTCNKKKVFLTDIKDGYTYILQTKIILTLILVGISWGLIGGAYQLLL
TIYAEKIFHTNIGILYTVQGAGLMIGSLLVNLYISNNKEKMKKAFGWAYFLQGFFFLGFILSNQLIFGIITLLCMRIAGG
IIVPLDTTLLQAYTHENMIGKVFSFHYSIYGSLIQLSMFITGWLLEILSPQMIGSLLATCCIFVSFIWLYLFYRGKLSEE
SIST

Sequences:

>Translated_404_residues
MSVSYRTLLKTNKNFNKLFYGQTLSVLGDWFHTVALLTFVYSITESPFMIALTFISKGLPQLLLSPFIGGVVDRFSKKNI
MIFTDITRGILVLTYILANYKIEIIFIANICLSVLSCLFEPAKQATLKNIVHENHFVTANSLSSTMNGFMSIMGASLGGI
IAQSLHIEFAFLVNSLSYFISAYFIYNMSIPAHDTCNKKKVFLTDIKDGYTYILQTKIILTLILVGISWGLIGGAYQLLL
TIYAEKIFHTNIGILYTVQGAGLMIGSLLVNLYISNNKEKMKKAFGWAYFLQGFFFLGFILSNQLIFGIITLLCMRIAGG
IIVPLDTTLLQAYTHENMIGKVFSFHYSIYGSLIQLSMFITGWLLEILSPQMIGSLLATCCIFVSFIWLYLFYRGKLSEE
SIST
>Mature_403_residues
SVSYRTLLKTNKNFNKLFYGQTLSVLGDWFHTVALLTFVYSITESPFMIALTFISKGLPQLLLSPFIGGVVDRFSKKNIM
IFTDITRGILVLTYILANYKIEIIFIANICLSVLSCLFEPAKQATLKNIVHENHFVTANSLSSTMNGFMSIMGASLGGII
AQSLHIEFAFLVNSLSYFISAYFIYNMSIPAHDTCNKKKVFLTDIKDGYTYILQTKIILTLILVGISWGLIGGAYQLLLT
IYAEKIFHTNIGILYTVQGAGLMIGSLLVNLYISNNKEKMKKAFGWAYFLQGFFFLGFILSNQLIFGIITLLCMRIAGGI
IVPLDTTLLQAYTHENMIGKVFSFHYSIYGSLIQLSMFITGWLLEILSPQMIGSLLATCCIFVSFIWLYLFYRGKLSEES
IST

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. TCR/tet family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45359; Mature: 45227

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVSYRTLLKTNKNFNKLFYGQTLSVLGDWFHTVALLTFVYSITESPFMIALTFISKGLP
CCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHH
QLLLSPFIGGVVDRFSKKNIMIFTDITRGILVLTYILANYKIEIIFIANICLSVLSCLFE
HHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHH
PAKQATLKNIVHENHFVTANSLSSTMNGFMSIMGASLGGIIAQSLHIEFAFLVNSLSYFI
HHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAYFIYNMSIPAHDTCNKKKVFLTDIKDGYTYILQTKIILTLILVGISWGLIGGAYQLLL
HHHHHEECCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TIYAEKIFHTNIGILYTVQGAGLMIGSLLVNLYISNNKEKMKKAFGWAYFLQGFFFLGFI
HHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
LSNQLIFGIITLLCMRIAGGIIVPLDTTLLQAYTHENMIGKVFSFHYSIYGSLIQLSMFI
HHHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGWLLEILSPQMIGSLLATCCIFVSFIWLYLFYRGKLSEESIST
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SVSYRTLLKTNKNFNKLFYGQTLSVLGDWFHTVALLTFVYSITESPFMIALTFISKGLP
CCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHH
QLLLSPFIGGVVDRFSKKNIMIFTDITRGILVLTYILANYKIEIIFIANICLSVLSCLFE
HHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHH
PAKQATLKNIVHENHFVTANSLSSTMNGFMSIMGASLGGIIAQSLHIEFAFLVNSLSYFI
HHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAYFIYNMSIPAHDTCNKKKVFLTDIKDGYTYILQTKIILTLILVGISWGLIGGAYQLLL
HHHHHEECCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TIYAEKIFHTNIGILYTVQGAGLMIGSLLVNLYISNNKEKMKKAFGWAYFLQGFFFLGFI
HHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
LSNQLIFGIITLLCMRIAGGIIVPLDTTLLQAYTHENMIGKVFSFHYSIYGSLIQLSMFI
HHHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGWLLEILSPQMIGSLLATCCIFVSFIWLYLFYRGKLSEESIST
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]