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The map label for this gene is 52143669

Identifier: 52143669

GI number: 52143669

Start: 1647845

End: 1649155

Strand: Direct

Name: 52143669

Synonym: BCZK1565

Alternate gene names: NA

Gene position: 1647845-1649155 (Clockwise)

Preceding gene: 52143670

Following gene: 52143668

Centisome position: 31.09

GC content: 35.39

Gene sequence:

>1311_bases
ATGTTTATTACTTCTGCAGCATATGGAACAAAAACGAAAAGGGGTAGCATGATGAGGGTAGAAGTATGGGGAGGAGCGGG
AGAATACGGTCGTTCCTGCTATTTCGTAAAAAATAAAGAGACAAAAATATTATTTGATTGTGGTATTAATCGATCATATG
AGGATAGTTATCCAAAAATAGAGCGGGAAGTTGTACCGTTTTTAGATGCAGTATTTTTATCACATATTCATGAAGATCAT
ACGATGGGCTTACCTTTATTAGCGAAGTATGGATATAAGAAAAAAATCTGGACAACTCGTTATACGAAGGAGCAACTTCC
CGCTTATTATGAAAAATGGAGAAACTACAATGTGATGCAAGGATGGAATGTGCCATATAACGACCAAAATGTGAAAGATT
TAAATTATATATATGTTGATGAGATTAGTAATCCGAATGAATGGATACAGATTACTCCTACATTGCGGTTTCAATGGGGG
TATAGTGGGCACGTATTAGGATCGGTTTGGTTTTTAGTGGATATGAGTCATACATATGTATTTTATTCTGGCGATTATTC
AGCAGAGTCTAACATACTACGAGCGAATTTACCTGAGAAATTGCGCGGCGATATAAAAGTTGCAATTGTAGATGCCGCTT
ATCATACTGATGATGTTTCGCAACATGAACGAGTAAACGAACTATGTACAGAAATTGAACGAGTTGCGGGGAATAAAGGG
GTAGCATTACTACCATTGCCACCCCTTGGTAGGGCGCAAGATATCATATTGTATTTATATGAAAAATATAAAGAATTTCC
CATTATAGTAGATCAAGAAATTTTAGATGGATTTGATGAGATGTTCGTATATAAAGATTGGATCAAAAATAATGAAGAAC
TTGAAGAGCTAATGGAGAGTTTAAAAAGAAACGTAATAGTTATGGATGATGACGGCGGTACGCAACATAGTTATGGAATA
GTTGTAATGAGTGATGCGAATATGCAAACGAAACGGGCTCAGTTATATTATGAACAAATTCGGCATGAAGAAAGAAATTC
TATTATCTTTACTGGGCATGTTGCTAAAGGGAGTTTTGCAGAAAAAGTTTTGAAAGAACGTATAGGTAAAGAATGTAGGG
TGAAGCGAGTTCCATATAAAGTTCATCAAAGTATAAGAGATGTGAAAGAGATGTTAAATACATTATTACCGGAACATACG
GTGTTAGTACACGCTTTAAAAGAGGATACAGATCGATTACAGAAAAAGCTTAGCACGGCAGGGTATGAAAATGTATATTC
ACTTACTATGGAACGTATAGAAGTTATTTAA

Upstream 100 bases:

>100_bases
CAGTAGAGACGTCAGCAACATTTATTTTTGCTCAATTTGAACAAGGAGAAGTATCTATTGGAATGGCGATGGCTGTCGTT
TCAGTTGGACTTACAACGCT

Downstream 100 bases:

>100_bases
CATGTAAAGGGGATAGGTATATGAAAAAAGTATTTGTATTCGTGAGTATTTTCTTTTGTTGTTTCTTTTATTCCGATAAG
GAAGGGTTTGCTGCTAGTCC

Product: zinc-dependent hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MFITSAAYGTKTKRGSMMRVEVWGGAGEYGRSCYFVKNKETKILFDCGINRSYEDSYPKIEREVVPFLDAVFLSHIHEDH
TMGLPLLAKYGYKKKIWTTRYTKEQLPAYYEKWRNYNVMQGWNVPYNDQNVKDLNYIYVDEISNPNEWIQITPTLRFQWG
YSGHVLGSVWFLVDMSHTYVFYSGDYSAESNILRANLPEKLRGDIKVAIVDAAYHTDDVSQHERVNELCTEIERVAGNKG
VALLPLPPLGRAQDIILYLYEKYKEFPIIVDQEILDGFDEMFVYKDWIKNNEELEELMESLKRNVIVMDDDGGTQHSYGI
VVMSDANMQTKRAQLYYEQIRHEERNSIIFTGHVAKGSFAEKVLKERIGKECRVKRVPYKVHQSIRDVKEMLNTLLPEHT
VLVHALKEDTDRLQKKLSTAGYENVYSLTMERIEVI

Sequences:

>Translated_436_residues
MFITSAAYGTKTKRGSMMRVEVWGGAGEYGRSCYFVKNKETKILFDCGINRSYEDSYPKIEREVVPFLDAVFLSHIHEDH
TMGLPLLAKYGYKKKIWTTRYTKEQLPAYYEKWRNYNVMQGWNVPYNDQNVKDLNYIYVDEISNPNEWIQITPTLRFQWG
YSGHVLGSVWFLVDMSHTYVFYSGDYSAESNILRANLPEKLRGDIKVAIVDAAYHTDDVSQHERVNELCTEIERVAGNKG
VALLPLPPLGRAQDIILYLYEKYKEFPIIVDQEILDGFDEMFVYKDWIKNNEELEELMESLKRNVIVMDDDGGTQHSYGI
VVMSDANMQTKRAQLYYEQIRHEERNSIIFTGHVAKGSFAEKVLKERIGKECRVKRVPYKVHQSIRDVKEMLNTLLPEHT
VLVHALKEDTDRLQKKLSTAGYENVYSLTMERIEVI
>Mature_436_residues
MFITSAAYGTKTKRGSMMRVEVWGGAGEYGRSCYFVKNKETKILFDCGINRSYEDSYPKIEREVVPFLDAVFLSHIHEDH
TMGLPLLAKYGYKKKIWTTRYTKEQLPAYYEKWRNYNVMQGWNVPYNDQNVKDLNYIYVDEISNPNEWIQITPTLRFQWG
YSGHVLGSVWFLVDMSHTYVFYSGDYSAESNILRANLPEKLRGDIKVAIVDAAYHTDDVSQHERVNELCTEIERVAGNKG
VALLPLPPLGRAQDIILYLYEKYKEFPIIVDQEILDGFDEMFVYKDWIKNNEELEELMESLKRNVIVMDDDGGTQHSYGI
VVMSDANMQTKRAQLYYEQIRHEERNSIIFTGHVAKGSFAEKVLKERIGKECRVKRVPYKVHQSIRDVKEMLNTLLPEHT
VLVHALKEDTDRLQKKLSTAGYENVYSLTMERIEVI

Specific function: Unknown

COG id: COG1782

COG function: function code R; Predicted metal-dependent RNase, consists of a metallo-beta-lactamase domain and an RNA-binding KH domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI7706427, Length=440, Percent_Identity=25, Blast_Score=128, Evalue=8e-30,
Organism=Homo sapiens, GI33300633, Length=439, Percent_Identity=23.0068337129841, Blast_Score=108, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI32566029, Length=440, Percent_Identity=22.5, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI32564696, Length=429, Percent_Identity=21.6783216783217, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24648013, Length=443, Percent_Identity=24.6049661399549, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI21358523, Length=434, Percent_Identity=23.2718894009217, Blast_Score=101, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022712
- InterPro:   IPR001279
- InterPro:   IPR004087
- InterPro:   IPR019975
- InterPro:   IPR004044
- InterPro:   IPR011108 [H]

Pfam domain/function: PF10996 Beta-Casp; PF07650 KH_2; PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 50837; Mature: 50837

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFITSAAYGTKTKRGSMMRVEVWGGAGEYGRSCYFVKNKETKILFDCGINRSYEDSYPKI
CEEECCCCCCCCCCCCEEEEEEECCCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCCHH
EREVVPFLDAVFLSHIHEDHTMGLPLLAKYGYKKKIWTTRYTKEQLPAYYEKWRNYNVMQ
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCEEEECCCHHHHHHHHHHHCCCCCEE
GWNVPYNDQNVKDLNYIYVDEISNPNEWIQITPTLRFQWGYSGHVLGSVWFLVDMSHTYV
CCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEEEEEECCCCCCHHHEEEEEEEECCEEE
FYSGDYSAESNILRANLPEKLRGDIKVAIVDAAYHTDDVSQHERVNELCTEIERVAGNKG
EEECCCCCCCCEEECCCCHHHCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCC
VALLPLPPLGRAQDIILYLYEKYKEFPIIVDQEILDGFDEMFVYKDWIKNNEELEELMES
EEEEECCCCCCHHHHHHHHHHHHCCCCEEECHHHHCCHHHHHHHHHHHCCHHHHHHHHHH
LKRNVIVMDDDGGTQHSYGIVVMSDANMQTKRAQLYYEQIRHEERNSIIFTGHVAKGSFA
HHCCEEEEECCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHH
EKVLKERIGKECRVKRVPYKVHQSIRDVKEMLNTLLPEHTVLVHALKEDTDRLQKKLSTA
HHHHHHHCCCHHEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
GYENVYSLTMERIEVI
CCHHHHHHHHHHHHCC
>Mature Secondary Structure
MFITSAAYGTKTKRGSMMRVEVWGGAGEYGRSCYFVKNKETKILFDCGINRSYEDSYPKI
CEEECCCCCCCCCCCCEEEEEEECCCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCCHH
EREVVPFLDAVFLSHIHEDHTMGLPLLAKYGYKKKIWTTRYTKEQLPAYYEKWRNYNVMQ
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCEEEECCCHHHHHHHHHHHCCCCCEE
GWNVPYNDQNVKDLNYIYVDEISNPNEWIQITPTLRFQWGYSGHVLGSVWFLVDMSHTYV
CCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEEEEEECCCCCCHHHEEEEEEEECCEEE
FYSGDYSAESNILRANLPEKLRGDIKVAIVDAAYHTDDVSQHERVNELCTEIERVAGNKG
EEECCCCCCCCEEECCCCHHHCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCC
VALLPLPPLGRAQDIILYLYEKYKEFPIIVDQEILDGFDEMFVYKDWIKNNEELEELMES
EEEEECCCCCCHHHHHHHHHHHHCCCCEEECHHHHCCHHHHHHHHHHHCCHHHHHHHHHH
LKRNVIVMDDDGGTQHSYGIVVMSDANMQTKRAQLYYEQIRHEERNSIIFTGHVAKGSFA
HHCCEEEEECCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHH
EKVLKERIGKECRVKRVPYKVHQSIRDVKEMLNTLLPEHTVLVHALKEDTDRLQKKLSTA
HHHHHHHCCCHHEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
GYENVYSLTMERIEVI
CCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]