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The map label for this gene is matE [H]

Identifier: 52143645

GI number: 52143645

Start: 1673248

End: 1674657

Strand: Direct

Name: matE [H]

Synonym: BCZK1591

Alternate gene names: 52143645

Gene position: 1673248-1674657 (Clockwise)

Preceding gene: 52143644

Following gene: 52143640

Centisome position: 31.57

GC content: 35.96

Gene sequence:

>1410_bases
TTGAAACCACCTACAGATAACAATAAAGAAGGTGCGGAGTCACATAAGTTAGAAAGTGAGAGTAAACCGATTTGGAAATC
GATGTCCATGTTTTTAGTACCGTTACTATTAAGTAATGTATTACAATCGGTTGGACAATTATTCGGTATGGTAGTAGTAG
GAAGATGGCTTGGAGTGAATGATTTAGCAGCCATATCGGCATTCTTTCCGCTATTTTTCTTACTCGTTTCATTTGTAATT
GGTATTGGTTCAGGTAGTTCTATTTTAATAGGTCAGGCGTTTGGAGCAAAAAACGAGGATCGTTTAAAAGCGATTGTTGG
TACGACGTTGACATTTACCTTTATTATTGGAGTTGTGTTGGCGATAGTAGGTAGTATTTTTGCGATGGATATTATGCGCC
TTATGGGAACGCCAGAAAATATTATTGAAATAAGTGTACATTATGCACGTATTTTATTTATATCGATGCCAGTATTATTT
TTATATTTCGCATACACAACATTTATGAGAGGGACAGGAGATTCTAAAACGCCATTTTATTTTTTAATTGTAAGTACAGC
GCTAAATATGATCTTATTACCGATTCTTATTTTTGGATGGTTAGGAGCTCCGAAATTAGATGTGTATGGAGCAGCCTATG
CTTCTGTTATATCTACAGTTATTACGTTTATTGTCATGTTAGTGTATTTAAAGAAAAAAAATCACCCACTACAATTAGAT
AGTACGGTAAGGAAATATCTTCGAATGGATTGGGATTTATTAAAGCTATTGCTACGACTCGGTATTCCAGCGAGTATTAA
TATGATATTAGTTTCATTATCAGAAATTGCGGTAATCGCGTTTGTAAATCGTTACGGTTCGGATGCAACAGCAGCTTATG
GGGTTGTGAACCAAGTTGCAAGTTATGTGCAAATGCCAGCAGTTAGTCTTGGTATTACAGTCTCCATTTTTGCTGCACAA
TCAATTGGTGCGAATCAATTTGATCGATTGCAGAAAGTTGTGAAGGCCGGAATTATTATGAACTACGTCATCGGTGGTGT
GTTAATATCTCTTATTTACTTGTTCTCAAGAGACATTCTATCACTATTTTTAACGAGTCAAACTACAATTGAAATTGCTC
ATAGCCTAGTTATGATTACATTATGGAGTTATTTAATTTTCGGGCATGCGCAAATTATTAGTGCAACAATGCGAGCAAGT
GGTACAGTATTATGGCCAACTGTTATCGGCGTCGTATCAATATGGCTTGTAGAAGTACCTGTAGCGTATTACCTTTCTTA
CCATACAAGTCTTGGCATAGAAGGGATATGGATTGGGTACCCAGCAGCGTTTATTGTCAGTTTAATACTACAATATGCAT
ATTATAAGCTTTCATGGCAGAAGAAACGAATTACACGATTAGTGAGTTAA

Upstream 100 bases:

>100_bases
AAGTTATAATAATACGAAAATGAATAGAAGTACATCATTATAACAACTATACAAAGAGATAGAAGTTAAAAAAGATTTTT
AATAGAAGGAGAAATGAAAT

Downstream 100 bases:

>100_bases
ATATTGAAAATGTCCCTAAGTTATTTTACTTAGGGACATTTTTTGTAAAGGTATCTTTATAAATAGCTTTTTAAAGTAAT
ATCAAAATGTTGTCTAATGA

Product: Na+ driven multidrug efflux pump

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 469; Mature: 469

Protein sequence:

>469_residues
MKPPTDNNKEGAESHKLESESKPIWKSMSMFLVPLLLSNVLQSVGQLFGMVVVGRWLGVNDLAAISAFFPLFFLLVSFVI
GIGSGSSILIGQAFGAKNEDRLKAIVGTTLTFTFIIGVVLAIVGSIFAMDIMRLMGTPENIIEISVHYARILFISMPVLF
LYFAYTTFMRGTGDSKTPFYFLIVSTALNMILLPILIFGWLGAPKLDVYGAAYASVISTVITFIVMLVYLKKKNHPLQLD
STVRKYLRMDWDLLKLLLRLGIPASINMILVSLSEIAVIAFVNRYGSDATAAYGVVNQVASYVQMPAVSLGITVSIFAAQ
SIGANQFDRLQKVVKAGIIMNYVIGGVLISLIYLFSRDILSLFLTSQTTIEIAHSLVMITLWSYLIFGHAQIISATMRAS
GTVLWPTVIGVVSIWLVEVPVAYYLSYHTSLGIEGIWIGYPAAFIVSLILQYAYYKLSWQKKRITRLVS

Sequences:

>Translated_469_residues
MKPPTDNNKEGAESHKLESESKPIWKSMSMFLVPLLLSNVLQSVGQLFGMVVVGRWLGVNDLAAISAFFPLFFLLVSFVI
GIGSGSSILIGQAFGAKNEDRLKAIVGTTLTFTFIIGVVLAIVGSIFAMDIMRLMGTPENIIEISVHYARILFISMPVLF
LYFAYTTFMRGTGDSKTPFYFLIVSTALNMILLPILIFGWLGAPKLDVYGAAYASVISTVITFIVMLVYLKKKNHPLQLD
STVRKYLRMDWDLLKLLLRLGIPASINMILVSLSEIAVIAFVNRYGSDATAAYGVVNQVASYVQMPAVSLGITVSIFAAQ
SIGANQFDRLQKVVKAGIIMNYVIGGVLISLIYLFSRDILSLFLTSQTTIEIAHSLVMITLWSYLIFGHAQIISATMRAS
GTVLWPTVIGVVSIWLVEVPVAYYLSYHTSLGIEGIWIGYPAAFIVSLILQYAYYKLSWQKKRITRLVS
>Mature_469_residues
MKPPTDNNKEGAESHKLESESKPIWKSMSMFLVPLLLSNVLQSVGQLFGMVVVGRWLGVNDLAAISAFFPLFFLLVSFVI
GIGSGSSILIGQAFGAKNEDRLKAIVGTTLTFTFIIGVVLAIVGSIFAMDIMRLMGTPENIIEISVHYARILFISMPVLF
LYFAYTTFMRGTGDSKTPFYFLIVSTALNMILLPILIFGWLGAPKLDVYGAAYASVISTVITFIVMLVYLKKKNHPLQLD
STVRKYLRMDWDLLKLLLRLGIPASINMILVSLSEIAVIAFVNRYGSDATAAYGVVNQVASYVQMPAVSLGITVSIFAAQ
SIGANQFDRLQKVVKAGIIMNYVIGGVLISLIYLFSRDILSLFLTSQTTIEIAHSLVMITLWSYLIFGHAQIISATMRAS
GTVLWPTVIGVVSIWLVEVPVAYYLSYHTSLGIEGIWIGYPAAFIVSLILQYAYYKLSWQKKRITRLVS

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=456, Percent_Identity=20.6140350877193, Blast_Score=88, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6321821, Length=374, Percent_Identity=21.1229946524064, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 51775; Mature: 51775

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]