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The map label for this gene is nheC [H]

Identifier: 52143534

GI number: 52143534

Start: 1798948

End: 1800027

Strand: Direct

Name: nheC [H]

Synonym: BCZK1700

Alternate gene names: 52143534

Gene position: 1798948-1800027 (Clockwise)

Preceding gene: 52143535

Following gene: 52143533

Centisome position: 33.94

GC content: 33.61

Gene sequence:

>1080_bases
ATGCAGAAACGATTTTATAAGAAATGTCTTTTAACATTAATGATTGCTGGGGTGGCAACGAGTAACGCATTTCCTTTACA
TACTTTTGCAGCAGAACAAAACGTAAAAGTACTACAAGAAAATGCGAAAGATTATTCTCTTGGTCCAGCAGGATTCCAAG
ATGTAATGGCACAAACAACATCGAGCATATTCGCAATGGATTCATATGCAAAGTTAATCCAAAATCAGCAAGAAACGGAT
TTAAGCAAAATAAGTTCGATTAATAGTGAGTTTAAAGGAAATATGATGCAGCACCAACGAGATGCAAAAATTAACGCGGC
GTATTGGTTAGATCATATGAAGCCGCAAATTATGAAAACGGATCAAAATATTATTAATTACAATAATACTTTTCAAGCGT
ATTATAATAGCATGTTAATAGCAATTGATCAAAAAGATAGCGTAAAGTTAAAAGCGGATTTAGAAAAATTGTATGCGGAT
ATTGTAAAGAATCAAAATGAGGTAGATGTATTATTAGGAGATTTGAAAGCCTTTCGTGATAGAATGGCGAAAGATACAAA
TAGCTTTAAAGAGGATACAAATCAACTAACCTCGATTTTGGCAAGTACGAATGCTGGAATCCCCGCTCTAGAGCAACAAA
TCAATACATATAATGATTCAATCAAAAAGAGTAATGATATGGTTATTGCTGGTGGTGTACTTTGCGTAGCGTTAATAACA
TGTCTTGCTGGCGGACCTATGATTGCCGTTGCGAAAAAAGATATTGCAAATGCAGAACGAGAAATCGCTAATTTAAAAGA
TAGAATTTCTGGAGCGCAAGCAGAAGTCGCAATTTTGACAGATGTAAAAAATAAAACAACAAATATGACTGAAACGATTG
ATGCAGCAATTACAGCACTACAAAACATATCAAATCAATGGTATACAGTAGGTGCAAAATATAATAATTTACTACAAAAC
GTAAAAGGAATTAGTCCGGAAGAGTTTACGTTTATAAAAGAAGATTTGAATACAGCGAAAGATAGTTGGAAAGACGTAAA
AGATTATACAGAAAAATTACATGAAGGCGTAGCGAAGTAA

Upstream 100 bases:

>100_bases
AAAGTCCGATTGGTTCAACTAATAATCAGTGGGGGATGAAGAAAACCCCCACTGATTAAAGTTTCACTTTATACCCTTAT
AAAGAAACTAGGTGAAAAGT

Downstream 100 bases:

>100_bases
ACAGTGGACTAGTTCTGCTGTTCATTTTTTTATCCTGTTTTTTTGTGAGAGTTGAACTTGTAATTTGATATATAAGTTAA
CTATGTGTTTTATCAATGGG

Product: enterotoxin C

Products: NA

Alternate protein names: Enterotoxin 40 kDa subunit [H]

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MQKRFYKKCLLTLMIAGVATSNAFPLHTFAAEQNVKVLQENAKDYSLGPAGFQDVMAQTTSSIFAMDSYAKLIQNQQETD
LSKISSINSEFKGNMMQHQRDAKINAAYWLDHMKPQIMKTDQNIINYNNTFQAYYNSMLIAIDQKDSVKLKADLEKLYAD
IVKNQNEVDVLLGDLKAFRDRMAKDTNSFKEDTNQLTSILASTNAGIPALEQQINTYNDSIKKSNDMVIAGGVLCVALIT
CLAGGPMIAVAKKDIANAEREIANLKDRISGAQAEVAILTDVKNKTTNMTETIDAAITALQNISNQWYTVGAKYNNLLQN
VKGISPEEFTFIKEDLNTAKDSWKDVKDYTEKLHEGVAK

Sequences:

>Translated_359_residues
MQKRFYKKCLLTLMIAGVATSNAFPLHTFAAEQNVKVLQENAKDYSLGPAGFQDVMAQTTSSIFAMDSYAKLIQNQQETD
LSKISSINSEFKGNMMQHQRDAKINAAYWLDHMKPQIMKTDQNIINYNNTFQAYYNSMLIAIDQKDSVKLKADLEKLYAD
IVKNQNEVDVLLGDLKAFRDRMAKDTNSFKEDTNQLTSILASTNAGIPALEQQINTYNDSIKKSNDMVIAGGVLCVALIT
CLAGGPMIAVAKKDIANAEREIANLKDRISGAQAEVAILTDVKNKTTNMTETIDAAITALQNISNQWYTVGAKYNNLLQN
VKGISPEEFTFIKEDLNTAKDSWKDVKDYTEKLHEGVAK
>Mature_359_residues
MQKRFYKKCLLTLMIAGVATSNAFPLHTFAAEQNVKVLQENAKDYSLGPAGFQDVMAQTTSSIFAMDSYAKLIQNQQETD
LSKISSINSEFKGNMMQHQRDAKINAAYWLDHMKPQIMKTDQNIINYNNTFQAYYNSMLIAIDQKDSVKLKADLEKLYAD
IVKNQNEVDVLLGDLKAFRDRMAKDTNSFKEDTNQLTSILASTNAGIPALEQQINTYNDSIKKSNDMVIAGGVLCVALIT
CLAGGPMIAVAKKDIANAEREIANLKDRISGAQAEVAILTDVKNKTTNMTETIDAAITALQNISNQWYTVGAKYNNLLQN
VKGISPEEFTFIKEDLNTAKDSWKDVKDYTEKLHEGVAK

Specific function: Cytotoxic protein, part of the enterotoxin complex. Responsible for binding to erythrocytes. This enterotoxin is thought to be the cause of the diarrheal form of gastroenteritis caused by food-borne strains of B.cereus [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Host cell membrane (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008414
- InterPro:   IPR010356 [H]

Pfam domain/function: PF05791 Bacillus_HBL [H]

EC number: NA

Molecular weight: Translated: 39998; Mature: 39998

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKRFYKKCLLTLMIAGVATSNAFPLHTFAAEQNVKVLQENAKDYSLGPAGFQDVMAQTT
CCHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHCCCCCCCCCCHHHHHHHHHH
SSIFAMDSYAKLIQNQQETDLSKISSINSEFKGNMMQHQRDAKINAAYWLDHMKPQIMKT
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHCCHHHHHC
DQNIINYNNTFQAYYNSMLIAIDQKDSVKLKADLEKLYADIVKNQNEVDVLLGDLKAFRD
CCHHHCCCCHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RMAKDTNSFKEDTNQLTSILASTNAGIPALEQQINTYNDSIKKSNDMVIAGGVLCVALIT
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHH
CLAGGPMIAVAKKDIANAEREIANLKDRISGAQAEVAILTDVKNKTTNMTETIDAAITAL
HHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHH
QNISNQWYTVGAKYNNLLQNVKGISPEEFTFIKEDLNTAKDSWKDVKDYTEKLHEGVAK
HHCCCCEEEECHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQKRFYKKCLLTLMIAGVATSNAFPLHTFAAEQNVKVLQENAKDYSLGPAGFQDVMAQTT
CCHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHCCCCCCCCCCHHHHHHHHHH
SSIFAMDSYAKLIQNQQETDLSKISSINSEFKGNMMQHQRDAKINAAYWLDHMKPQIMKT
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHCCHHHHHC
DQNIINYNNTFQAYYNSMLIAIDQKDSVKLKADLEKLYADIVKNQNEVDVLLGDLKAFRD
CCHHHCCCCHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RMAKDTNSFKEDTNQLTSILASTNAGIPALEQQINTYNDSIKKSNDMVIAGGVLCVALIT
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHH
CLAGGPMIAVAKKDIANAEREIANLKDRISGAQAEVAILTDVKNKTTNMTETIDAAITAL
HHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHH
QNISNQWYTVGAKYNNLLQNVKGISPEEFTFIKEDLNTAKDSWKDVKDYTEKLHEGVAK
HHCCCCEEEECHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7693651; 8319899 [H]