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The map label for this gene is phoP [H]

Identifier: 52143445

GI number: 52143445

Start: 1915803

End: 1916492

Strand: Direct

Name: phoP [H]

Synonym: BCZK1789

Alternate gene names: 52143445

Gene position: 1915803-1916492 (Clockwise)

Preceding gene: 52143446

Following gene: 52143444

Centisome position: 36.14

GC content: 33.62

Gene sequence:

>690_bases
ATGCCAACAATTTTAGTTTTAGAAGATGAAATGCCTATTCGTAGTTTTATCGTCTTAAATTTGAAACGTGCTGGATTTTA
TGTATTAGAAGCAAGTACTGGAGAAGAAGCGTTACAGATTTTATGTGAACATACTGTTGATGTAGCATTGCTTGATGTAA
TGTTACCAGGAATGGATGGTTTTCAAGTTTGTAAAACGATTCGGAAAGAAAATAAAAAAATAGGAATTATTATGTTAACT
GCGCGCGTACAAAATGAAGATAAGGTACAAGGGTTAGGAATTGGTGCAGATGATTATATTGCAAAGCCGTTTAGTCCAGT
GGAACTAACTGCACGTATACAATCGTTACTAAGAAGAATAGAAGTACATGATGAAAAAGCGAATACTATTATATCTGGCC
CGTTTTCTTTAAATATAATAGAAGAAAGATTATATAAAAGCGGACAACTAGTCGAATTAACCCCTACAGAGTATATGATA
TTACAGTATTTAATGAATCAGGCTTCAAAGCCAGTTTCACGTGATGAAATTTTAAATATGATTTGGGGAACGAATTATGT
AGGTGAGACGAAAGTAGTAGATGTAAATATGAGGCGGTTACGTCAAAAGATAGAATGTAATCCATCAGAACCTGAATTTA
TTCTTACTGTGTGGGGAAAAGGATATGTGTGGAAGGAAAGTATAAGATGA

Upstream 100 bases:

>100_bases
TCTCACGTATATGCTGTACCGAAACAACCACATTTTGAAAAAGTGAAAGCATATGTGAAGCCGCTAGCGGATTATCAACA
AGAGTAGGGAGGTGGAAATG

Downstream 100 bases:

>100_bases
AAAGAAAAGTGACTTTATATTTTATGACGGTCATTATACTTATGCTTGTATTATTTGAAGTCGTATTTTCAGTCTCCGTT
TATCGATATTATTATAACGG

Product: alkaline phosphatase synthesis response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MPTILVLEDEMPIRSFIVLNLKRAGFYVLEASTGEEALQILCEHTVDVALLDVMLPGMDGFQVCKTIRKENKKIGIIMLT
ARVQNEDKVQGLGIGADDYIAKPFSPVELTARIQSLLRRIEVHDEKANTIISGPFSLNIIEERLYKSGQLVELTPTEYMI
LQYLMNQASKPVSRDEILNMIWGTNYVGETKVVDVNMRRLRQKIECNPSEPEFILTVWGKGYVWKESIR

Sequences:

>Translated_229_residues
MPTILVLEDEMPIRSFIVLNLKRAGFYVLEASTGEEALQILCEHTVDVALLDVMLPGMDGFQVCKTIRKENKKIGIIMLT
ARVQNEDKVQGLGIGADDYIAKPFSPVELTARIQSLLRRIEVHDEKANTIISGPFSLNIIEERLYKSGQLVELTPTEYMI
LQYLMNQASKPVSRDEILNMIWGTNYVGETKVVDVNMRRLRQKIECNPSEPEFILTVWGKGYVWKESIR
>Mature_228_residues
PTILVLEDEMPIRSFIVLNLKRAGFYVLEASTGEEALQILCEHTVDVALLDVMLPGMDGFQVCKTIRKENKKIGIIMLTA
RVQNEDKVQGLGIGADDYIAKPFSPVELTARIQSLLRRIEVHDEKANTIISGPFSLNIIEERLYKSGQLVELTPTEYMIL
QYLMNQASKPVSRDEILNMIWGTNYVGETKVVDVNMRRLRQKIECNPSEPEFILTVWGKGYVWKESIR

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=226, Percent_Identity=36.283185840708, Blast_Score=169, Evalue=1e-43,
Organism=Escherichia coli, GI1786599, Length=221, Percent_Identity=41.1764705882353, Blast_Score=165, Evalue=3e-42,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=35.2422907488987, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=33.7777777777778, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=32.8828828828829, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI87082012, Length=219, Percent_Identity=35.1598173515982, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=34.3478260869565, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=34.9775784753363, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1790860, Length=220, Percent_Identity=32.2727272727273, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=31.8385650224215, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1790552, Length=221, Percent_Identity=33.4841628959276, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=33.1877729257642, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI1787229, Length=235, Percent_Identity=28.936170212766, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=28.3898305084746, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1788550, Length=115, Percent_Identity=33.0434782608696, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1790299, Length=139, Percent_Identity=30.2158273381295, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1790437, Length=134, Percent_Identity=29.1044776119403, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788713, Length=136, Percent_Identity=28.6764705882353, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26089; Mature: 25958

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTILVLEDEMPIRSFIVLNLKRAGFYVLEASTGEEALQILCEHTVDVALLDVMLPGMDG
CCEEEEEECCCCCCEEEEEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCH
FQVCKTIRKENKKIGIIMLTARVQNEDKVQGLGIGADDYIAKPFSPVELTARIQSLLRRI
HHHHHHHHHCCCEEEEEEEEEEECCCCCEEEECCCCCHHHCCCCCCHHHHHHHHHHHHHH
EVHDEKANTIISGPFSLNIIEERLYKSGQLVELTPTEYMILQYLMNQASKPVSRDEILNM
HCCCCCCCEEEECCEEEHHHHHHHHCCCCEEEECCHHHHHHHHHHHHCCCCCCHHHHHHH
IWGTNYVGETKVVDVNMRRLRQKIECNPSEPEFILTVWGKGYVWKESIR
HHCCCCCCCEEEEEHHHHHHHHHHCCCCCCCCEEEEECCCCEEECCCCC
>Mature Secondary Structure 
PTILVLEDEMPIRSFIVLNLKRAGFYVLEASTGEEALQILCEHTVDVALLDVMLPGMDG
CEEEEEECCCCCCEEEEEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCH
FQVCKTIRKENKKIGIIMLTARVQNEDKVQGLGIGADDYIAKPFSPVELTARIQSLLRRI
HHHHHHHHHCCCEEEEEEEEEEECCCCCEEEECCCCCHHHCCCCCCHHHHHHHHHHHHHH
EVHDEKANTIISGPFSLNIIEERLYKSGQLVELTPTEYMILQYLMNQASKPVSRDEILNM
HCCCCCCCEEEECCEEEHHHHHHHHCCCCEEEECCHHHHHHHHHHHHCCCCCCHHHHHHH
IWGTNYVGETKVVDVNMRRLRQKIECNPSEPEFILTVWGKGYVWKESIR
HHCCCCCCCEEEEEHHHHHHHHHHCCCCCCCCEEEEECCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]